Danio rerio

0 known processes

xpc

xeroderma pigmentosum, complementation group C

(Aliases: wu:fb12d09,zgc:113032,wu:fb12d05)

xpc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular nitrogen compound metabolic process GO:0034641 290 0.341
Mouse
nitrogen compound metabolic process GO:0006807 319 0.260
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.230
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.148
Mouse
heterocycle metabolic process GO:0046483 290 0.144
Mouse
rna metabolic process GO:0016070 219 0.141
chromosome organization GO:0051276 31 0.134
cellular macromolecule metabolic process GO:0044260 391 0.113
Mouse
nucleic acid metabolic process GO:0090304 244 0.099
Mouse
organelle organization GO:0006996 227 0.098
gene expression GO:0010467 252 0.095
regulation of rna metabolic process GO:0051252 224 0.087
dna metabolic process GO:0006259 27 0.086
Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.082
response to stress GO:0006950 263 0.081
Mouse
regulation of gene expression GO:0010468 265 0.079
regulation of macromolecule metabolic process GO:0060255 317 0.079
regulation of cellular metabolic process GO:0031323 320 0.079
nucleic acid templated transcription GO:0097659 181 0.078
entrainment of circadian clock GO:0009649 2 0.074
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.074
regulation of circadian rhythm GO:0042752 4 0.073
nucleobase containing compound metabolic process GO:0006139 274 0.073
Mouse
single organism organelle organization GO:1902589 199 0.066
cellular response to radiation GO:0071478 4 0.066
protein polyubiquitination GO:0000209 4 0.062
cellular response to light stimulus GO:0071482 4 0.062
regulation of metabolic process GO:0019222 359 0.060
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.056
blood vessel morphogenesis GO:0048514 216 0.049
heterocycle biosynthetic process GO:0018130 215 0.049
regulation of macromolecule biosynthetic process GO:0010556 225 0.049
meiotic nuclear division GO:0007126 4 0.048
regulation of rna biosynthetic process GO:2001141 213 0.047
regulation of nitrogen compound metabolic process GO:0051171 251 0.047
single organism metabolic process GO:0044710 217 0.047
Mouse
response to abiotic stimulus GO:0009628 122 0.046
Mouse
signal transduction GO:0007165 455 0.046
regulation of signaling GO:0023051 235 0.045
regulation of cytokine production GO:0001817 3 0.044
blood vessel development GO:0001568 246 0.044
cellular response to stress GO:0033554 62 0.042
Mouse
response to external stimulus GO:0009605 264 0.042
maintenance of location GO:0051235 4 0.042
response to chemical GO:0042221 320 0.042
rna localization GO:0006403 4 0.041
transcription dna templated GO:0006351 181 0.041
response to nutrient GO:0007584 3 0.041
rna biosynthetic process GO:0032774 181 0.041
larval development GO:0002164 2 0.040
cellular response to external stimulus GO:0071496 2 0.040
regulation of primary metabolic process GO:0080090 311 0.039
tube morphogenesis GO:0035239 349 0.038
negative regulation of biological process GO:0048519 304 0.035
Mouse
female sex differentiation GO:0046660 4 0.034
chromatin modification GO:0016568 21 0.033
protein modification process GO:0036211 100 0.032
regulation of nucleic acid templated transcription GO:1903506 213 0.031
stem cell maintenance GO:0019827 4 0.030
ribonucleoside monophosphate catabolic process GO:0009158 4 0.030
atp catabolic process GO:0006200 4 0.030
cellular component biogenesis GO:0044085 178 0.030
meiosis i GO:0007127 1 0.030
positive regulation of cell cycle GO:0045787 3 0.030
aging GO:0007568 2 0.030
protein metabolic process GO:0019538 183 0.029
cellular nitrogen compound biosynthetic process GO:0044271 218 0.029
regulation of binding GO:0051098 3 0.027
digestive system development GO:0055123 289 0.027
cellular protein modification process GO:0006464 100 0.027
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.027
negative regulation of macromolecule metabolic process GO:0010605 76 0.027
regulation of transcription dna templated GO:0006355 213 0.027
covalent chromatin modification GO:0016569 20 0.027
response to radiation GO:0009314 51 0.026
Mouse
regulation of stem cell differentiation GO:2000736 4 0.026
cytokinesis GO:0000910 3 0.026
macromolecule modification GO:0043412 111 0.026
negative regulation of rna biosynthetic process GO:1902679 45 0.025
purine nucleoside monophosphate catabolic process GO:0009128 4 0.025
cell motility GO:0048870 244 0.025
b cell mediated immunity GO:0019724 3 0.025
cellular response to dna damage stimulus GO:0006974 24 0.025
Mouse
positive regulation of cellular component biogenesis GO:0044089 3 0.025
cellular protein metabolic process GO:0044267 129 0.025
lipid storage GO:0019915 1 0.024
negative regulation of transcription dna templated GO:0045892 45 0.024
amine metabolic process GO:0009308 2 0.023
regulation of production of molecular mediator of immune response GO:0002700 1 0.023
response to uv GO:0009411 3 0.023
Mouse
sister chromatid cohesion GO:0007062 2 0.023
regulation of response to stimulus GO:0048583 269 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.023
cellular component movement GO:0006928 335 0.023
positive regulation of dna metabolic process GO:0051054 1 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.023
cell substrate adhesion GO:0031589 4 0.022
immunoglobulin mediated immune response GO:0016064 3 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
negative regulation of biosynthetic process GO:0009890 55 0.021
nucleoside monophosphate catabolic process GO:0009125 4 0.021
fertilization GO:0009566 3 0.021
regulation of reproductive process GO:2000241 4 0.021
regulation of response to nutrient levels GO:0032107 1 0.021
cellular amine metabolic process GO:0044106 2 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
response to drug GO:0042493 3 0.020
regulation of cell cycle GO:0051726 52 0.020
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
dna catabolic process GO:0006308 1 0.020
nucleobase containing compound biosynthetic process GO:0034654 205 0.020
negative regulation of metabolic process GO:0009892 86 0.020
negative regulation of stem cell differentiation GO:2000737 2 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
cell cycle g1 s phase transition GO:0044843 1 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
negative regulation of gene expression GO:0010629 65 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.019
toll like receptor signaling pathway GO:0002224 4 0.019
regulation of synapse assembly GO:0051963 3 0.019
negative regulation of cellular biosynthetic process GO:0031327 55 0.019
segmentation GO:0035282 97 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
localization of cell GO:0051674 244 0.018
regulation of dna replication GO:0006275 3 0.018
dna repair GO:0006281 6 0.018
Mouse
entrainment of circadian clock by photoperiod GO:0043153 1 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
regulation of response to cytokine stimulus GO:0060759 3 0.018
positive regulation of immune effector process GO:0002699 3 0.018
digestive tract development GO:0048565 265 0.018
glucose homeostasis GO:0042593 1 0.018
intracellular signal transduction GO:0035556 85 0.018
regulation of mrna splicing via spliceosome GO:0048024 3 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
cellular component morphogenesis GO:0032989 336 0.018
regulation of signal transduction GO:0009966 225 0.017
nuclear transport GO:0051169 4 0.017
development of primary female sexual characteristics GO:0046545 4 0.017
response to biotic stimulus GO:0009607 97 0.017
cellular component assembly GO:0022607 170 0.017
positive regulation of biological process GO:0048518 253 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
cellular biosynthetic process GO:0044249 286 0.017
rna transport GO:0050658 2 0.017
recombinational repair GO:0000725 1 0.017
cellular ketone metabolic process GO:0042180 11 0.017
negative regulation of nucleic acid templated transcription GO:1903507 45 0.017
multicellular organism growth GO:0035264 4 0.017
gastrulation GO:0007369 208 0.017
regulation of protein catabolic process GO:0042176 1 0.016
cellular response to oxygen levels GO:0071453 1 0.016
convergent extension GO:0060026 118 0.016
negative regulation of cellular process GO:0048523 283 0.016
Mouse
vasculature development GO:0001944 278 0.016
cell migration GO:0016477 237 0.016
female gonad development GO:0008585 4 0.016
exocytosis GO:0006887 1 0.016
regulation of cell activation GO:0050865 1 0.016
positive regulation of secretion GO:0051047 1 0.016
positive regulation of map kinase activity GO:0043406 3 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
microtubule organizing center organization GO:0031023 1 0.016
angiogenesis GO:0001525 158 0.016
cellular response to starvation GO:0009267 1 0.015
g2 dna damage checkpoint GO:0031572 3 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
regulation of protein complex assembly GO:0043254 3 0.015
positive regulation of stress activated mapk cascade GO:0032874 3 0.015
regulation of cell communication GO:0010646 232 0.015
positive regulation of cytokine production GO:0001819 2 0.015
cellular response to nutrient levels GO:0031669 2 0.015
cell projection morphogenesis GO:0048858 244 0.015
intracellular mrna localization GO:0008298 1 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
cellular response to decreased oxygen levels GO:0036294 1 0.015
protein autoubiquitination GO:0051865 3 0.015
macromolecule localization GO:0033036 54 0.015
regulation of protein transport GO:0051223 3 0.015
nucleic acid transport GO:0050657 2 0.015
meiotic cell cycle process GO:1903046 3 0.015
steroid hormone secretion GO:0035929 1 0.015
cell projection organization GO:0030030 284 0.015
hormone transport GO:0009914 2 0.015
organic substance biosynthetic process GO:1901576 289 0.014
regulation of microtubule cytoskeleton organization GO:0070507 3 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
biosynthetic process GO:0009058 294 0.014
cellular response to hypoxia GO:0071456 1 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
digestive tract morphogenesis GO:0048546 231 0.014
telomere organization GO:0032200 1 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
apoptotic process GO:0006915 116 0.014
meiotic chromosome segregation GO:0045132 3 0.014
peptide transport GO:0015833 1 0.014
regionalization GO:0003002 274 0.014
multi organism process GO:0051704 134 0.014
mononuclear cell proliferation GO:0032943 1 0.014
eye development GO:0001654 277 0.014
leukocyte proliferation GO:0070661 1 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
lymphocyte proliferation GO:0046651 1 0.014
cell part morphogenesis GO:0032990 246 0.014
positive regulation of cell activation GO:0050867 1 0.014
nuclear export GO:0051168 1 0.014
positive regulation of catabolic process GO:0009896 4 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.014
oxoacid metabolic process GO:0043436 31 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
regulation of synapse organization GO:0050807 3 0.014
cellular component disassembly GO:0022411 1 0.014
negative regulation of dna metabolic process GO:0051053 4 0.014
regulation of protein ubiquitination GO:0031396 3 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
response to glucose GO:0009749 3 0.013
single organism nuclear import GO:1902593 3 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.013
establishment of rna localization GO:0051236 3 0.013
embryonic organ development GO:0048568 381 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
type i interferon production GO:0032606 2 0.013
response to monosaccharide GO:0034284 3 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
cell morphogenesis GO:0000902 289 0.013
negative regulation of defense response GO:0031348 2 0.013
peptidyl serine modification GO:0018209 2 0.013
positive regulation of protein kinase b signaling GO:0051897 1 0.013
membrane invagination GO:0010324 1 0.013
positive regulation of transport GO:0051050 2 0.013
germ line stem cell maintenance GO:0030718 2 0.013
rna 3 end processing GO:0031123 2 0.012
anterior posterior pattern specification GO:0009952 152 0.012
regulation of leukocyte mediated immunity GO:0002703 1 0.012
oocyte anterior posterior axis specification GO:0007314 4 0.012
retinal rod cell development GO:0046548 4 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.012
type b pancreatic cell development GO:0003323 4 0.012
spermatid differentiation GO:0048515 2 0.012
response to hydrogen peroxide GO:0042542 3 0.012
organic acid metabolic process GO:0006082 31 0.012
response to amino acid GO:0043200 2 0.012
stem cell division GO:0017145 1 0.012
cytoskeleton organization GO:0007010 96 0.012
photoreceptor cell outer segment organization GO:0035845 9 0.012
regulation of cell differentiation GO:0045595 142 0.012
germ line stem cell division GO:0042078 1 0.012
locomotion GO:0040011 313 0.012
protein homooligomerization GO:0051260 3 0.012
regulation of phospholipase activity GO:0010517 2 0.012
response to external biotic stimulus GO:0043207 97 0.012
gtp catabolic process GO:0006184 2 0.012
regulation of translational initiation GO:0006446 1 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
Mouse
macroautophagy GO:0016236 1 0.012
chemosensory behavior GO:0007635 1 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
macromolecular complex disassembly GO:0032984 1 0.012
negative regulation of dna replication GO:0008156 2 0.012
mesenchymal cell differentiation GO:0048762 87 0.012
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
positive regulation of programmed cell death GO:0043068 29 0.011
centrosome organization GO:0051297 1 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
protein stabilization GO:0050821 2 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
protein import into nucleus GO:0006606 3 0.011
neurotransmitter transport GO:0006836 2 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
Mouse
positive regulation of leukocyte mediated immunity GO:0002705 1 0.011
microtubule based process GO:0007017 60 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
regulation of programmed cell death GO:0043067 101 0.011
cilium organization GO:0044782 71 0.011
regeneration GO:0031099 91 0.011
regulation of dna recombination GO:0000018 2 0.011
death GO:0016265 121 0.011
organelle fission GO:0048285 23 0.011
response to other organism GO:0051707 97 0.011
system process GO:0003008 185 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
maternal determination of anterior posterior axis embryo GO:0008358 4 0.011
activation of mapk activity GO:0000187 3 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
regulation of biological quality GO:0065008 263 0.011
endocrine process GO:0050886 2 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
chromatin organization GO:0006325 22 0.011
mitochondrion organization GO:0007005 4 0.011
protein localization to plasma membrane GO:0072659 1 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
regulation of myotube differentiation GO:0010830 2 0.011
cellular response to organic substance GO:0071310 105 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of cytokine mediated signaling pathway GO:0001959 3 0.011
protein localization to nucleus GO:0034504 3 0.011
negative regulation of protein complex assembly GO:0031333 1 0.010
negative regulation of mitosis GO:0045839 3 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
regulation of jun kinase activity GO:0043506 3 0.010
somitogenesis GO:0001756 87 0.010
mrna transport GO:0051028 2 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
regulation of jak stat cascade GO:0046425 3 0.010
positive regulation of histone modification GO:0031058 1 0.010
tube closure GO:0060606 1 0.010
positive regulation of secretion by cell GO:1903532 1 0.010
negative regulation of kinase activity GO:0033673 4 0.010
response to corticosteroid GO:0031960 1 0.010
protein targeting to nucleus GO:0044744 3 0.010
specification of axis polarity GO:0065001 4 0.010
protein localization GO:0008104 40 0.010
cell surface receptor signaling pathway GO:0007166 325 0.010
protein complex disassembly GO:0043241 1 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
regulation of calcium ion transport GO:0051924 2 0.010
negative regulation of rna metabolic process GO:0051253 48 0.010
carbohydrate homeostasis GO:0033500 1 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
developmental growth involved in morphogenesis GO:0060560 86 0.010

xpc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
disease of metabolism DOID:0014667 0 0.019
inherited metabolic disorder DOID:655 0 0.019
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
nervous system disease DOID:863 0 0.013