|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
1 |
0.995
|
Fly |
|
|
pronuclear migration
|
GO:0035046 |
1 |
0.989
|
Worm |
|
|
larval development
|
GO:0002164 |
2 |
0.986
|
Worm |
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
1 |
0.914
|
Fly |
|
|
cognition
|
GO:0050890 |
1 |
0.868
|
Fly |
|
|
specification of axis polarity
|
GO:0065001 |
4 |
0.863
|
Worm |
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.850
|
Human Yeast Fly |
|
|
midbrain development
|
GO:0030901 |
28 |
0.817
|
Human |
|
|
oocyte axis specification
|
GO:0007309 |
5 |
0.787
|
Fly |
|
|
oxidation reduction process
|
GO:0055114 |
41 |
0.713
|
Yeast |
|
|
generation of neurons
|
GO:0048699 |
385 |
0.704
|
|
|
|
neurological system process
|
GO:0050877 |
62 |
0.700
|
Fly |
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
4 |
0.666
|
|
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.655
|
Human Yeast |
|
|
protein stabilization
|
GO:0050821 |
2 |
0.652
|
Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.648
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.642
|
Fly |
|
|
single organism localization
|
GO:1902578 |
225 |
0.634
|
Zebrafish Mouse Worm |
|
|
mitotic cell cycle embryonic
|
GO:0045448 |
2 |
0.610
|
Fly |
|
|
head development
|
GO:0060322 |
303 |
0.606
|
Human Zebrafish |
|
|
central nervous system development
|
GO:0007417 |
387 |
0.584
|
Human Zebrafish |
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.548
|
Human Yeast |
|
|
fertilization
|
GO:0009566 |
3 |
0.536
|
Worm |
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
4 |
0.522
|
|
|
|
cell fate specification
|
GO:0001708 |
68 |
0.517
|
Worm |
|
|
oocyte development
|
GO:0048599 |
14 |
0.504
|
Fly |
|
|
oocyte construction
|
GO:0007308 |
5 |
0.502
|
Fly |
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.486
|
Human Yeast |
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.471
|
Human Yeast Fly |
|
|
aging
|
GO:0007568 |
2 |
0.462
|
Worm |
|
|
muscle structure development
|
GO:0061061 |
196 |
0.447
|
|
|
|
phagocytosis engulfment
|
GO:0006911 |
1 |
0.417
|
Zebrafish |
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.417
|
Fly |
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.412
|
Human |
|
|
establishment of localization
|
GO:0051234 |
244 |
0.401
|
Zebrafish Mouse Worm |
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
3 |
0.396
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.388
|
Yeast |
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.373
|
Human Yeast Fly |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
3 |
0.367
|
|
|
|
compound eye development
|
GO:0048749 |
2 |
0.362
|
|
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.361
|
Human Yeast |
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.355
|
Human Yeast |
|
|
heart development
|
GO:0007507 |
313 |
0.348
|
Zebrafish |
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.345
|
Fly |
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
43 |
0.338
|
Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
48 |
0.337
|
Yeast Worm |
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.334
|
Human |
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.331
|
Fly |
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.330
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.328
|
Human Yeast |
|
|
single organism biosynthetic process
|
GO:0044711 |
71 |
0.323
|
Yeast |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
43 |
0.322
|
Yeast |
|
|
neural nucleus development
|
GO:0048857 |
15 |
0.312
|
Human |
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.308
|
Human |
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.304
|
Human Yeast |
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
4 |
0.302
|
Yeast |
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.300
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.295
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
4 |
0.294
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.294
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.290
|
Human Yeast |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
4 |
0.290
|
Fly |
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.286
|
Yeast Fly |
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.283
|
Human Yeast |
|
|
establishment of cell polarity
|
GO:0030010 |
18 |
0.281
|
Worm |
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.275
|
Human |
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.265
|
Fly |
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
61 |
0.256
|
Yeast |
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.255
|
Yeast Fly |
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.253
|
Human Yeast Fly |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.246
|
|
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.240
|
Fly |
|
|
nuclear migration
|
GO:0007097 |
3 |
0.239
|
Worm |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.235
|
|
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
3 |
0.230
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.230
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
77 |
0.226
|
Mouse Worm |
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.224
|
|
|
|
behavior
|
GO:0007610 |
74 |
0.215
|
Worm Fly |
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.213
|
Human |
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.212
|
Yeast Fly |
|
|
hatching
|
GO:0035188 |
4 |
0.212
|
Worm |
|
|
regulation of ion transport
|
GO:0043269 |
22 |
0.208
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
24 |
0.208
|
Yeast |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
8 |
0.207
|
Yeast Mouse Fly |
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
29 |
0.206
|
Worm Fly |
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
5 |
0.205
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
4 |
0.203
|
Fly |
|
|
regulation of neurogenesis
|
GO:0050767 |
87 |
0.201
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
2 |
0.201
|
Yeast |
|
|
regulation of molecular function
|
GO:0065009 |
70 |
0.200
|
Yeast |
|
|
cellular component assembly
|
GO:0022607 |
170 |
0.198
|
Yeast |
|
|
ras protein signal transduction
|
GO:0007265 |
7 |
0.198
|
Yeast Fly |
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.195
|
Fly |
|
|
stem cell fate commitment
|
GO:0048865 |
1 |
0.194
|
|
|
|
sensory organ development
|
GO:0007423 |
393 |
0.190
|
|
|
|
axis specification
|
GO:0009798 |
43 |
0.189
|
Worm Fly |
|
|
organophosphate metabolic process
|
GO:0019637 |
37 |
0.184
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
28 |
0.183
|
|
|
|
signal transduction
|
GO:0007165 |
455 |
0.182
|
Yeast Mouse Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
0 |
0.179
|
|
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.177
|
Fly |
|
|
system process
|
GO:0003008 |
185 |
0.176
|
Fly |
|
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.175
|
|
|
|
heparan sulfate proteoglycan biosynthetic process
|
GO:0015012 |
5 |
0.174
|
|
|
|
adult behavior
|
GO:0030534 |
2 |
0.172
|
|
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.172
|
|
|
|
gene expression
|
GO:0010467 |
252 |
0.171
|
Human Fly |
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.171
|
Human Yeast |
|
|
cellular localization
|
GO:0051641 |
97 |
0.171
|
Mouse Worm |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
8 |
0.171
|
|
|
|
oogenesis
|
GO:0048477 |
14 |
0.169
|
Fly |
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.164
|
Human Yeast |
|
|
heart process
|
GO:0003015 |
71 |
0.164
|
|
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.162
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.158
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
15 |
0.158
|
Fly |
|
|
establishment of spindle orientation
|
GO:0051294 |
10 |
0.152
|
Worm |
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.152
|
|
|
|
neuron projection development
|
GO:0031175 |
180 |
0.151
|
|
|
|
response to metal ion
|
GO:0010038 |
34 |
0.148
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
14 |
0.147
|
|
|
|
response to chemical
|
GO:0042221 |
320 |
0.147
|
|
|
|
cell maturation
|
GO:0048469 |
23 |
0.147
|
Fly |
|
|
single fertilization
|
GO:0007338 |
3 |
0.146
|
Worm |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
9 |
0.144
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
2 |
0.143
|
|
|
|
axonogenesis
|
GO:0007409 |
152 |
0.142
|
|
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.141
|
Human |
|
|
establishment of mitotic spindle orientation
|
GO:0000132 |
10 |
0.140
|
Worm |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
5 |
0.140
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
3 |
0.139
|
|
|
|
chromosome segregation
|
GO:0007059 |
12 |
0.136
|
Fly |
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.133
|
|
|
|
chemosensory behavior
|
GO:0007635 |
1 |
0.132
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.132
|
Worm Fly |
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.131
|
Human |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
87 |
0.129
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
2 |
0.128
|
Fly |
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.127
|
Human Fly |
|
|
striated muscle cell differentiation
|
GO:0051146 |
129 |
0.126
|
|
|
|
eye development
|
GO:0001654 |
277 |
0.125
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
11 |
0.125
|
|
|
|
chromosome organization
|
GO:0051276 |
31 |
0.124
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
2 |
0.123
|
|
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.123
|
Human Yeast |
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.122
|
|
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.122
|
Human Yeast |
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.121
|
Human |
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.119
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.118
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
4 |
0.118
|
Worm |
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.118
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.117
|
Worm |
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.116
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
52 |
0.115
|
Worm |
|
|
multi organism process
|
GO:0051704 |
134 |
0.114
|
Yeast Worm Fly |
|
|
regulation of cell development
|
GO:0060284 |
100 |
0.112
|
|
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.111
|
Human |
|
|
camera type eye development
|
GO:0043010 |
222 |
0.111
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
65 |
0.111
|
Human |
|
|
heart contraction
|
GO:0060047 |
71 |
0.110
|
|
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.109
|
Fly |
|
|
developmental maturation
|
GO:0021700 |
34 |
0.109
|
Fly |
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.109
|
|
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.109
|
Human Yeast |
|
|
cell cycle
|
GO:0007049 |
93 |
0.108
|
Yeast Worm Fly |
|
|
asymmetric protein localization
|
GO:0008105 |
6 |
0.103
|
Worm |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.103
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
9 |
0.103
|
|
|
|
membrane invagination
|
GO:0010324 |
1 |
0.102
|
Zebrafish |
|
|
regulation of cell shape
|
GO:0008360 |
1 |
0.102
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.102
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
0 |
0.101
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
7 |
0.101
|
Yeast |
|
|
digestive system development
|
GO:0055123 |
289 |
0.101
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.101
|
Yeast |
|
|
negative regulation of protein transport
|
GO:0051224 |
3 |
0.101
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
43 |
0.101
|
Fly |
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.100
|
Human |
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.100
|
Human |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
3 |
0.099
|
Yeast |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
1 |
0.099
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.098
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
9 |
0.097
|
|
|
|
cell fate commitment
|
GO:0045165 |
99 |
0.097
|
Worm Fly |
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.097
|
Worm |
|
|
membrane repolarization
|
GO:0086009 |
2 |
0.096
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
7 |
0.096
|
Worm |
|
|
microtubule based movement
|
GO:0007018 |
33 |
0.095
|
|
|
|
brain development
|
GO:0007420 |
293 |
0.094
|
Human Zebrafish |
|
|
cell motility
|
GO:0048870 |
244 |
0.094
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.092
|
Fly |
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.091
|
Human |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
5 |
0.090
|
|
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.089
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
55 |
0.088
|
|
|
|
intracellular transport
|
GO:0046907 |
32 |
0.088
|
Mouse |
|
|
nuclear transport
|
GO:0051169 |
4 |
0.087
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
3 |
0.087
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
178 |
0.086
|
Yeast |
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.086
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
2 |
0.085
|
|
|
|
protein acetylation
|
GO:0006473 |
2 |
0.085
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
55 |
0.085
|
Yeast |
|
|
blood vessel morphogenesis
|
GO:0048514 |
216 |
0.083
|
|
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.083
|
Human |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
4 |
0.082
|
|
|
|
cell projection organization
|
GO:0030030 |
284 |
0.082
|
|
|
|
estrogen metabolic process
|
GO:0008210 |
2 |
0.081
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
7 |
0.081
|
|
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.080
|
Fly |
|
|
phosphorylation
|
GO:0016310 |
69 |
0.080
|
Fly |
|
|
rna localization
|
GO:0006403 |
4 |
0.080
|
|
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.078
|
Human Yeast |
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.078
|
|
|
|
reproduction
|
GO:0000003 |
40 |
0.078
|
Yeast Worm Fly |
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.078
|
Fly |
|
|
inner ear development
|
GO:0048839 |
126 |
0.077
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.075
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.074
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.074
|
Fly |
|
|
homeostatic process
|
GO:0042592 |
142 |
0.073
|
|
|
|
microtubule based process
|
GO:0007017 |
60 |
0.073
|
Worm Fly |
|
|
androgen metabolic process
|
GO:0008209 |
2 |
0.072
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
3 |
0.072
|
|
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.072
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
4 |
0.072
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
25 |
0.071
|
Worm |
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
4 |
0.071
|
|
|
|
neuron development
|
GO:0048666 |
262 |
0.071
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
64 |
0.071
|
Yeast Worm Fly |
|
|
g2 dna damage checkpoint
|
GO:0031572 |
3 |
0.070
|
|
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.070
|
|
|
|
membrane organization
|
GO:0061024 |
21 |
0.070
|
Zebrafish |
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.069
|
|
|
|
wound healing
|
GO:0042060 |
90 |
0.069
|
|
|
|
regulation of mrna splicing via spliceosome
|
GO:0048024 |
3 |
0.068
|
|
|
|
oocyte differentiation
|
GO:0009994 |
14 |
0.068
|
Fly |
|
|
single organism reproductive process
|
GO:0044702 |
40 |
0.068
|
Yeast Worm Fly |
|
|
single organism behavior
|
GO:0044708 |
24 |
0.067
|
Fly |
|
|
single organism transport
|
GO:0044765 |
206 |
0.066
|
Zebrafish Mouse |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
55 |
0.065
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
146 |
0.065
|
|
|
|
nuclear import
|
GO:0051170 |
3 |
0.065
|
|
|
|
determination of heart left right asymmetry
|
GO:0061371 |
117 |
0.065
|
|
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.064
|
Worm Fly |
|
|
endomembrane system organization
|
GO:0010256 |
13 |
0.064
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.063
|
|
|
|
thermosensory behavior
|
GO:0040040 |
1 |
0.063
|
Fly |
|
|
receptor mediated endocytosis
|
GO:0006898 |
6 |
0.063
|
Worm |
|
|
cellular lipid metabolic process
|
GO:0044255 |
36 |
0.063
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.063
|
Human Yeast |
|
|
digestive tract development
|
GO:0048565 |
265 |
0.063
|
|
|
|
dephosphorylation
|
GO:0016311 |
11 |
0.062
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
2 |
0.062
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
6 |
0.062
|
Yeast |
|
|
pyruvate metabolic process
|
GO:0006090 |
1 |
0.062
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.061
|
|
|
|
forebrain development
|
GO:0030900 |
96 |
0.061
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.061
|
Yeast |
|
|
rna stabilization
|
GO:0043489 |
4 |
0.060
|
|
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.060
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
18 |
0.060
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
1 |
0.060
|
|
|
|
cell cycle process
|
GO:0022402 |
53 |
0.059
|
Yeast Worm |
|
|
muscle cell differentiation
|
GO:0042692 |
139 |
0.059
|
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.058
|
Yeast |
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.058
|
Human |
|
|
gastrulation
|
GO:0007369 |
208 |
0.058
|
|
|
|
photoreceptor cell morphogenesis
|
GO:0008594 |
1 |
0.057
|
|
|
|
rna transport
|
GO:0050658 |
2 |
0.057
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
4 |
0.057
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
3 |
0.057
|
Yeast |
|
|
myofibril assembly
|
GO:0030239 |
48 |
0.057
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.056
|
|
|
|
centrosome organization
|
GO:0051297 |
1 |
0.056
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
1 |
0.056
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.056
|
Yeast |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
12 |
0.056
|
Yeast |
|
|
vasculature development
|
GO:0001944 |
278 |
0.055
|
|
|
|
eye morphogenesis
|
GO:0048592 |
144 |
0.055
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
8 |
0.055
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
14 |
0.055
|
Fly |
|
|
nuclear export
|
GO:0051168 |
1 |
0.054
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
97 |
0.054
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.053
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
20 |
0.053
|
Worm |
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
48 |
0.053
|
Human |
|
|
cell fate determination
|
GO:0001709 |
7 |
0.053
|
Worm Fly |
|
|
macromolecular complex subunit organization
|
GO:0043933 |
74 |
0.052
|
Yeast |
|
|
regulation of cell death
|
GO:0010941 |
103 |
0.052
|
Yeast |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.052
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
16 |
0.050
|
Yeast |
|
|
mononuclear cell proliferation
|
GO:0032943 |
1 |
0.050
|
|
|
|
spermatid differentiation
|
GO:0048515 |
2 |
0.050
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
2 |
0.050
|
|
|
|
transmembrane transport
|
GO:0055085 |
120 |
0.049
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
2 |
0.048
|
|
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
28 |
0.048
|
Fly |
|
|
axon development
|
GO:0061564 |
166 |
0.048
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
3 |
0.048
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.047
|
Fly |
|
|
mesenchymal cell development
|
GO:0014031 |
78 |
0.047
|
|
|
|
growth
|
GO:0040007 |
174 |
0.047
|
Yeast |
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.047
|
|
|
|
chemotaxis
|
GO:0006935 |
104 |
0.047
|
|
|
|
cellular hormone metabolic process
|
GO:0034754 |
19 |
0.047
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
27 |
0.047
|
Yeast Fly |
|
|
maintenance of location
|
GO:0051235 |
4 |
0.047
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
19 |
0.046
|
|
|
|
regulation of protein binding
|
GO:0043393 |
3 |
0.046
|
|
|
|
cell aging
|
GO:0007569 |
2 |
0.046
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.046
|
|
|
|
muscle tissue development
|
GO:0060537 |
110 |
0.045
|
|
|
|
translational initiation
|
GO:0006413 |
3 |
0.045
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.045
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
18 |
0.045
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
2 |
0.045
|
|
|
|
lipid metabolic process
|
GO:0006629 |
52 |
0.044
|
|
|
|
response to uv
|
GO:0009411 |
3 |
0.044
|
|
|
|
protein import
|
GO:0017038 |
3 |
0.044
|
|
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.043
|
Human |
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.043
|
|
|
|
organism emergence from protective structure
|
GO:0071684 |
4 |
0.043
|
Worm |
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.043
|
Yeast |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
3 |
0.043
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
1 |
0.042
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
32 |
0.042
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
3 |
0.042
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
23 |
0.042
|
|
|
|
regionalization
|
GO:0003002 |
274 |
0.041
|
Worm |
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.041
|
Human Yeast |
|
|
gtp catabolic process
|
GO:0006184 |
2 |
0.041
|
|
|
|
organic substance transport
|
GO:0071702 |
58 |
0.041
|
Mouse |
|
|
organic substance catabolic process
|
GO:1901575 |
28 |
0.041
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
4 |
0.041
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.041
|
|
|
|
localization of cell
|
GO:0051674 |
244 |
0.041
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
21 |
0.040
|
Fly |
|
|
phagocytosis
|
GO:0006909 |
3 |
0.040
|
Zebrafish |
|
|
meiotic cell cycle process
|
GO:1903046 |
3 |
0.040
|
Yeast |
|
|
response to corticosteroid
|
GO:0031960 |
1 |
0.040
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.040
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
24 |
0.040
|
|
|
|
neural crest cell differentiation
|
GO:0014033 |
72 |
0.039
|
|
|
|
protein acylation
|
GO:0043543 |
3 |
0.039
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
4 |
0.039
|
|
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.039
|
|
|
|
pole plasm assembly
|
GO:0007315 |
4 |
0.039
|
|
|
|
regulation of binding
|
GO:0051098 |
3 |
0.039
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
1 |
0.038
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.038
|
Human |
|
|
regulation of localization
|
GO:0032879 |
104 |
0.038
|
|
|
|
reproductive process
|
GO:0022414 |
40 |
0.038
|
Yeast Worm Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
33 |
0.038
|
Worm Fly |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
5 |
0.038
|
Yeast |
|
|
stem cell maintenance
|
GO:0019827 |
4 |
0.037
|
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.037
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
2 |
0.037
|
|
|
|
circulatory system process
|
GO:0003013 |
87 |
0.037
|
|
|
|
gtp metabolic process
|
GO:0046039 |
4 |
0.037
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.037
|
|
|
|
sexual reproduction
|
GO:0019953 |
36 |
0.036
|
Yeast Worm Fly |
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.036
|
Human Yeast |
|
|
establishment of organelle localization
|
GO:0051656 |
45 |
0.036
|
Worm |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
1 |
0.036
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
53 |
0.036
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
4 |
0.035
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
11 |
0.035
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
26 |
0.035
|
Fly |
|
|
establishment of mitotic spindle localization
|
GO:0040001 |
12 |
0.035
|
Worm |
|
|
dna damage checkpoint
|
GO:0000077 |
6 |
0.035
|
Yeast |
|
|
heart looping
|
GO:0001947 |
94 |
0.034
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
4 |
0.034
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
56 |
0.034
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.034
|
|
|
|
heart morphogenesis
|
GO:0003007 |
156 |
0.034
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
4 |
0.034
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
2 |
0.034
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
2 |
0.033
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
22 |
0.033
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.033
|
|
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.033
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
3 |
0.032
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
18 |
0.032
|
Fly |
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
74 |
0.032
|
Yeast |
|
|
single organism intracellular transport
|
GO:1902582 |
25 |
0.032
|
Mouse |
|
|
embryonic heart tube development
|
GO:0035050 |
133 |
0.032
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.032
|
Yeast |
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
4 |
0.032
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
2 |
0.032
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
21 |
0.032
|
Fly |
|
|
startle response
|
GO:0001964 |
4 |
0.032
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
2 |
0.032
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
1 |
0.031
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.031
|
Human |
|
|
striated muscle tissue development
|
GO:0014706 |
110 |
0.031
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
3 |
0.031
|
|
|
|
muscle cell development
|
GO:0055001 |
115 |
0.030
|
|
|
|
cellular response to organic substance
|
GO:0071310 |
105 |
0.030
|
|
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.030
|
|
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.030
|
Human |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
2 |
0.030
|
|
|
|
protein localization
|
GO:0008104 |
40 |
0.030
|
Mouse Worm |
|
|
negative regulation of intracellular transport
|
GO:0032387 |
3 |
0.030
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
15 |
0.030
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
4 |
0.029
|
|
|
|
response to drug
|
GO:0042493 |
3 |
0.029
|
|
|
|
vitamin a biosynthetic process
|
GO:0035238 |
1 |
0.029
|
|
|
|
skeletal system development
|
GO:0001501 |
181 |
0.029
|
|
|
|
spindle localization
|
GO:0051653 |
12 |
0.029
|
Worm |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
46 |
0.029
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
68 |
0.028
|
|
|
|
nucleus localization
|
GO:0051647 |
8 |
0.028
|
Worm |
|
|
embryonic pattern specification
|
GO:0009880 |
44 |
0.028
|
|
|
|
vesicle localization
|
GO:0051648 |
27 |
0.028
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
48 |
0.028
|
Human |
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
45 |
0.027
|
Human |
|
|
response to organic substance
|
GO:0010033 |
153 |
0.027
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.027
|
|
|
|
retina homeostasis
|
GO:0001895 |
12 |
0.027
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
14 |
0.027
|
Fly |
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.027
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
48 |
0.027
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.027
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
51 |
0.027
|
|
|
|
fat soluble vitamin metabolic process
|
GO:0006775 |
4 |
0.027
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
46 |
0.027
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
11 |
0.027
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
68 |
0.026
|
|
|
|
catabolic process
|
GO:0009056 |
32 |
0.026
|
|
|
|
neuron projection guidance
|
GO:0097485 |
86 |
0.026
|
|
|
|
death
|
GO:0016265 |
121 |
0.026
|
Yeast |
|
|
striated muscle cell development
|
GO:0055002 |
108 |
0.026
|
|
|
|
gliogenesis
|
GO:0042063 |
45 |
0.026
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
4 |
0.026
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
2 |
0.026
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
114 |
0.025
|
|
|
|
neuroblast differentiation
|
GO:0014016 |
1 |
0.025
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
42 |
0.025
|
|
|
|
adherens junction organization
|
GO:0034332 |
4 |
0.025
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
55 |
0.025
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
3 |
0.025
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
2 |
0.025
|
|
|
|
metal ion transport
|
GO:0030001 |
58 |
0.025
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
2 |
0.025
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
59 |
0.025
|
Human |
|
|
response to growth factor
|
GO:0070848 |
39 |
0.024
|
|
|
|
axon ensheathment in central nervous system
|
GO:0032291 |
2 |
0.024
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
4 |
0.024
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
1 |
0.024
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
3 |
0.024
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
2 |
0.024
|
|
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.024
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.024
|
Fly |
|
|
germ cell development
|
GO:0007281 |
22 |
0.024
|
Fly |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
148 |
0.024
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
1 |
0.024
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
1 |
0.024
|
|
|
|
cytoplasm organization
|
GO:0007028 |
4 |
0.023
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
85 |
0.023
|
|
|
|
cell junction organization
|
GO:0034330 |
11 |
0.023
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
108 |
0.023
|
|
|
|
lipid storage
|
GO:0019915 |
1 |
0.023
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.023
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
44 |
0.023
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
5 |
0.023
|
Fly |
|
|
response to ketone
|
GO:1901654 |
1 |
0.022
|
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.022
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
67 |
0.022
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
23 |
0.022
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
90 |
0.022
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
2 |
0.022
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
3 |
0.022
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
23 |
0.022
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
2 |
0.022
|
|
|
|
regulation of growth
|
GO:0040008 |
42 |
0.022
|
|
|
|
cellular response to stress
|
GO:0033554 |
62 |
0.022
|
Yeast |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.022
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
4 |
0.022
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.021
|
|
|
|
cell migration
|
GO:0016477 |
237 |
0.021
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.021
|
|
|
|
regulation of photoreceptor cell differentiation
|
GO:0046532 |
2 |
0.021
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
35 |
0.021
|
Worm Fly |
|
|
limbic system development
|
GO:0021761 |
16 |
0.021
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
30 |
0.021
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
1 |
0.021
|
|