Danio rerio

104 known processes

zeb2a

zinc finger E-box binding homeobox 2a

(Aliases: si:dkey-52o2.2,wu:fc92g08,MGC175265,sip1a)

zeb2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ morphogenesis GO:0048562 274 0.891
tube morphogenesis GO:0035239 349 0.733
embryonic organ development GO:0048568 381 0.731
convergent extension GO:0060026 118 0.681
chordate embryonic development GO:0043009 271 0.659
signal transduction GO:0007165 455 0.646
morphogenesis of an epithelium GO:0002009 333 0.534
larval development GO:0002164 2 0.518
gastrulation GO:0007369 208 0.492
negative regulation of cell communication GO:0010648 96 0.418
skeletal system development GO:0001501 181 0.397
negative regulation of cellular process GO:0048523 283 0.387
digestive tract development GO:0048565 265 0.358
eye development GO:0001654 277 0.338
neural tube formation GO:0001841 16 0.338
Mouse
determination of heart left right asymmetry GO:0061371 117 0.337
localization of cell GO:0051674 244 0.333
negative regulation of biological process GO:0048519 304 0.318
immune system process GO:0002376 241 0.308
Fly
digestive system development GO:0055123 289 0.292
mesenchymal cell development GO:0014031 78 0.285
central nervous system development GO:0007417 387 0.281
Mouse
regulation of signal transduction GO:0009966 225 0.279
determination of left right symmetry GO:0007368 179 0.278
hemopoiesis GO:0030097 183 0.276
negative regulation of signaling GO:0023057 96 0.271
regulation of signaling GO:0023051 235 0.270
embryonic skeletal system morphogenesis GO:0048704 93 0.269
convergent extension involved in gastrulation GO:0060027 71 0.265
neural tube development GO:0021915 62 0.254
Mouse
nucleic acid templated transcription GO:0097659 181 0.254
Human Mouse Fly
regulation of developmental process GO:0050793 247 0.245
Zebrafish Mouse
regulation of cell communication GO:0010646 232 0.244
negative regulation of signal transduction GO:0009968 94 0.241
retina development in camera type eye GO:0060041 146 0.240
regulation of stem cell proliferation GO:0072091 2 0.232
organic substance biosynthetic process GO:1901576 289 0.222
Human Mouse Fly
regulation of metabolic process GO:0019222 359 0.219
Human Mouse Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.215
Human Mouse Fly
cellular response to chemical stimulus GO:0070887 157 0.203
regulation of neural precursor cell proliferation GO:2000177 3 0.196
epithelial tube morphogenesis GO:0060562 148 0.176
Mouse
regionalization GO:0003002 274 0.174
response to chemical GO:0042221 320 0.172
camera type eye development GO:0043010 222 0.169
enzyme linked receptor protein signaling pathway GO:0007167 106 0.167
head development GO:0060322 303 0.167
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.166
nucleic acid metabolic process GO:0090304 244 0.166
Human Mouse Fly
regulation of response to stimulus GO:0048583 269 0.164
cellular component assembly involved in morphogenesis GO:0010927 107 0.160
negative regulation of response to stimulus GO:0048585 104 0.157
myeloid cell differentiation GO:0030099 86 0.151
regulation of cellular metabolic process GO:0031323 320 0.148
Human Mouse Fly
cilium assembly GO:0042384 58 0.146
skeletal system morphogenesis GO:0048705 102 0.144
cellular nitrogen compound biosynthetic process GO:0044271 218 0.139
Human Mouse Fly
positive regulation of epithelial cell proliferation GO:0050679 1 0.138
cellular component morphogenesis GO:0032989 336 0.134
regulation of epithelial cell proliferation GO:0050678 3 0.130
response to other organism GO:0051707 97 0.128
Fly
neuron projection morphogenesis GO:0048812 161 0.124
Fly
liver development GO:0001889 96 0.121
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.121
Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.120
Fly
neural crest formation GO:0014029 14 0.119
positive regulation of cellular process GO:0048522 201 0.119
Human Mouse
ameboidal type cell migration GO:0001667 143 0.117
cell part morphogenesis GO:0032990 246 0.112
Fly
regulation of biological quality GO:0065008 263 0.111
muscle structure development GO:0061061 196 0.109
sensory organ morphogenesis GO:0090596 200 0.108
regulation of gene expression GO:0010468 265 0.108
Human Mouse Fly
mesenchyme development GO:0060485 127 0.107
specification of symmetry GO:0009799 204 0.107
positive regulation of cell communication GO:0010647 56 0.105
Mouse
primary neural tube formation GO:0014020 1 0.103
Mouse
determination of bilateral symmetry GO:0009855 204 0.102
muscle cell development GO:0055001 115 0.102
heart development GO:0007507 313 0.101
regulation of macromolecule metabolic process GO:0060255 317 0.098
Human Mouse Fly
neuron differentiation GO:0030182 353 0.096
Fly
somatic muscle development GO:0007525 4 0.091
positive regulation of catabolic process GO:0009896 4 0.091
mesenchymal cell differentiation GO:0048762 87 0.090
positive regulation of metabolic process GO:0009893 108 0.090
Human Mouse
organic cyclic compound metabolic process GO:1901360 301 0.088
Human Mouse Fly
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.087
regulation of primary metabolic process GO:0080090 311 0.082
Human Mouse Fly
regulation of multicellular organism growth GO:0040014 4 0.082
embryonic skeletal system development GO:0048706 97 0.081
muscle cell differentiation GO:0042692 139 0.081
aromatic compound biosynthetic process GO:0019438 217 0.080
Human Mouse Fly
cell motility GO:0048870 244 0.080
cell substrate adhesion GO:0031589 4 0.080
digestive tract morphogenesis GO:0048546 231 0.079
vasculature development GO:0001944 278 0.079
response to organic substance GO:0010033 153 0.074
system process GO:0003008 185 0.074
epithelial tube formation GO:0072175 19 0.073
Mouse
response to external stimulus GO:0009605 264 0.073
Fly
definitive hemopoiesis GO:0060216 18 0.073
inositol lipid mediated signaling GO:0048017 2 0.073
cellular biosynthetic process GO:0044249 286 0.072
Human Mouse Fly
lipid storage GO:0019915 1 0.072
tube closure GO:0060606 1 0.071
Mouse
regulation of cell proliferation GO:0042127 37 0.071
cellular macromolecule metabolic process GO:0044260 391 0.071
Human Mouse Fly
muscle tissue development GO:0060537 110 0.069
striated muscle cell differentiation GO:0051146 129 0.068
connective tissue development GO:0061448 99 0.066
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.066
cell migration to the midline involved in heart development GO:0003318 12 0.066
embryonic cranial skeleton morphogenesis GO:0048701 90 0.064
extrinsic apoptotic signaling pathway GO:0097191 3 0.064
neuron remodeling GO:0016322 1 0.064
positive regulation of biological process GO:0048518 253 0.064
Human Mouse
gene expression GO:0010467 252 0.062
Human Mouse Fly
leukocyte differentiation GO:0002521 25 0.062
regulation of intracellular signal transduction GO:1902531 57 0.061
Mouse
muscle cell migration GO:0014812 4 0.060
organonitrogen compound biosynthetic process GO:1901566 47 0.060
aging GO:0007568 2 0.060
negative regulation of synapse assembly GO:0051964 2 0.060
regulation of autophagy GO:0010506 3 0.059
generation of neurons GO:0048699 385 0.058
Fly
somite development GO:0061053 96 0.058
multicellular organism growth GO:0035264 4 0.058
chemotaxis GO:0006935 104 0.057
Fly
morphogenesis of embryonic epithelium GO:0016331 30 0.056
Mouse
neural crest cell differentiation GO:0014033 72 0.056
Mouse
growth GO:0040007 174 0.055
neuromuscular process controlling balance GO:0050885 3 0.055
cell migration involved in gastrulation GO:0042074 79 0.054
cilium organization GO:0044782 71 0.054
cellular response to endogenous stimulus GO:0071495 68 0.054
hepaticobiliary system development GO:0061008 98 0.054
actin cytoskeleton organization GO:0030036 63 0.054
forebrain anterior posterior pattern specification GO:0021797 3 0.054
positive regulation of myeloid cell differentiation GO:0045639 2 0.053
embryonic epithelial tube formation GO:0001838 17 0.052
Mouse
regulation of transcription dna templated GO:0006355 213 0.051
Human Mouse Fly
rna polyadenylation GO:0043631 2 0.051
gland development GO:0048732 143 0.050
Fly
stem cell proliferation GO:0072089 4 0.050
brain development GO:0007420 293 0.050
Mouse
female sex differentiation GO:0046660 4 0.050
transmission of nerve impulse GO:0019226 19 0.049
muscle fiber development GO:0048747 52 0.049
behavior GO:0007610 74 0.049
stem cell differentiation GO:0048863 117 0.049
locomotion GO:0040011 313 0.048
development of primary female sexual characteristics GO:0046545 4 0.048
embryonic heart tube morphogenesis GO:0003143 108 0.048
regulation of macromolecule biosynthetic process GO:0010556 225 0.048
Human Mouse Fly
response to external biotic stimulus GO:0043207 97 0.048
Fly
axon ensheathment GO:0008366 18 0.048
regulation of multicellular organismal development GO:2000026 223 0.048
Zebrafish Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.047
Fly
striated muscle tissue development GO:0014706 110 0.047
neuroblast proliferation GO:0007405 2 0.047
cartilage development GO:0051216 96 0.046
nucleobase containing compound biosynthetic process GO:0034654 205 0.046
Human Mouse Fly
cell projection assembly GO:0030031 64 0.046
regulation of cellular biosynthetic process GO:0031326 245 0.046
Human Mouse Fly
myotube differentiation GO:0014902 45 0.045
regulation of cell matrix adhesion GO:0001952 1 0.045
positive regulation of cellular metabolic process GO:0031325 94 0.045
Human Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.045
embryonic viscerocranium morphogenesis GO:0048703 52 0.044
heart morphogenesis GO:0003007 156 0.043
heart looping GO:0001947 94 0.043
neuron development GO:0048666 262 0.043
Fly
regulation of purine nucleotide catabolic process GO:0033121 2 0.043
olfactory lobe development GO:0021988 4 0.042
autophagy GO:0006914 4 0.042
cellular protein metabolic process GO:0044267 129 0.041
Mouse
regulation of protein complex assembly GO:0043254 3 0.041
cell surface receptor signaling pathway GO:0007166 325 0.040
neuronal stem cell maintenance GO:0097150 2 0.040
eye morphogenesis GO:0048592 144 0.040
regulation of cell death GO:0010941 103 0.039
negative regulation of cell proliferation GO:0008285 8 0.039
cellular response to organic substance GO:0071310 105 0.039
positive regulation of cellular catabolic process GO:0031331 3 0.038
camera type eye morphogenesis GO:0048593 108 0.038
phagocytosis GO:0006909 3 0.038
negative regulation of axon guidance GO:1902668 1 0.037
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.037
Human Mouse Fly
negative regulation of macromolecule metabolic process GO:0010605 76 0.037
Human Mouse Fly
motor neuron axon guidance GO:0008045 23 0.037
Fly
nose development GO:0043584 3 0.036
establishment of monopolar cell polarity GO:0061162 2 0.036
regulation of immune system process GO:0002682 34 0.036
cardioblast migration GO:0003260 7 0.036
regulation of catalytic activity GO:0050790 55 0.036
Mouse
multicellular organism reproduction GO:0032504 35 0.036
Fly
negative regulation of myeloid cell differentiation GO:0045638 1 0.036
epithelial cell differentiation GO:0030855 116 0.035
Mouse
regulation of erythrocyte differentiation GO:0045646 2 0.035
axis specification GO:0009798 43 0.035
pharyngeal system development GO:0060037 18 0.035
positive regulation of cell cycle GO:0045787 3 0.034
response to biotic stimulus GO:0009607 97 0.034
Fly
ovulation cycle GO:0042698 2 0.034
regulation of mesenchymal cell proliferation GO:0010464 1 0.034
protein targeting to nucleus GO:0044744 3 0.034
cellular component assembly GO:0022607 170 0.034
positive regulation of rna metabolic process GO:0051254 59 0.034
Human Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.033
Human Mouse Fly
mesenchymal cell proliferation GO:0010463 1 0.033
female gonad development GO:0008585 4 0.033
mesoderm development GO:0007498 88 0.033
Fly
positive regulation of protein kinase b signaling GO:0051897 1 0.033
neural crest cell development GO:0014032 62 0.032
Mouse
regulation of nucleotide catabolic process GO:0030811 2 0.032
sensory organ development GO:0007423 393 0.032
regulation of dna templated transcription in response to stress GO:0043620 0 0.032
macromolecular complex assembly GO:0065003 35 0.032
phosphorylation GO:0016310 69 0.032
Mouse
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.031
cellular amine metabolic process GO:0044106 2 0.031
positive regulation of neural precursor cell proliferation GO:2000179 1 0.031
organic cyclic compound biosynthetic process GO:1901362 223 0.031
Human Mouse Fly
dorsal convergence GO:0060030 14 0.031
cell projection morphogenesis GO:0048858 244 0.031
Fly
cell proliferation GO:0008283 80 0.031
Mouse
phosphate containing compound metabolic process GO:0006796 108 0.031
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.030
Human Mouse Fly
cytoskeleton organization GO:0007010 96 0.030
positive regulation of gtp catabolic process GO:0033126 1 0.030
stem cell development GO:0048864 82 0.030
regulation of embryonic development GO:0045995 47 0.030
Zebrafish
protein modification process GO:0036211 100 0.030
Mouse
angiogenesis GO:0001525 158 0.029
response to endogenous stimulus GO:0009719 83 0.029
protein complex biogenesis GO:0070271 30 0.029
cellular nitrogen compound metabolic process GO:0034641 290 0.029
Human Mouse Fly
negative regulation of protein phosphorylation GO:0001933 4 0.029
guanosine containing compound metabolic process GO:1901068 4 0.029
negative chemotaxis GO:0050919 1 0.028
myelination GO:0042552 18 0.028
positive regulation of cytoskeleton organization GO:0051495 3 0.028
protein metabolic process GO:0019538 183 0.028
Mouse
biosynthetic process GO:0009058 294 0.028
Human Mouse Fly
rna biosynthetic process GO:0032774 181 0.028
Human Mouse Fly
heterocycle metabolic process GO:0046483 290 0.028
Human Mouse Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.028
Human Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.028
maintenance of location GO:0051235 4 0.027
axonogenesis GO:0007409 152 0.027
Fly
negative regulation of developmental process GO:0051093 65 0.027
developmental growth GO:0048589 166 0.027
regulation of gtpase activity GO:0043087 2 0.026
transcription dna templated GO:0006351 181 0.026
Human Mouse Fly
stem cell maintenance GO:0019827 4 0.026
cranial nerve development GO:0021545 42 0.026
positive regulation of molecular function GO:0044093 33 0.026
Mouse
anterior posterior axis specification GO:0009948 20 0.026
compound eye development GO:0048749 2 0.026
neuronal action potential GO:0019228 18 0.026
axis elongation GO:0003401 31 0.026
spinal cord development GO:0021510 46 0.026
amine metabolic process GO:0009308 2 0.026
positive regulation of neuron death GO:1901216 1 0.026
single organism organelle organization GO:1902589 199 0.026
small molecule metabolic process GO:0044281 77 0.025
regulation of nucleic acid templated transcription GO:1903506 213 0.025
Human Mouse Fly
anterior posterior pattern specification GO:0009952 152 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
regulation of growth GO:0040008 42 0.025
single organism metabolic process GO:0044710 217 0.025
Mouse
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.025
pancreas development GO:0031016 84 0.025
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.025
antimicrobial humoral response GO:0019730 2 0.025
Fly
cellular response to extracellular stimulus GO:0031668 2 0.024
protein homotrimerization GO:0070207 1 0.024
developmental cell growth GO:0048588 52 0.024
forebrain development GO:0030900 96 0.024
Mouse
regulation of cellular protein catabolic process GO:1903362 1 0.024
regulation of synapse assembly GO:0051963 3 0.024
cellular response to starvation GO:0009267 1 0.024
phosphorus metabolic process GO:0006793 109 0.023
Mouse
cilium morphogenesis GO:0060271 85 0.023
long chain fatty acid metabolic process GO:0001676 1 0.023
positive regulation of neuron apoptotic process GO:0043525 1 0.023
negative regulation of chemotaxis GO:0050922 4 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
Zebrafish Mouse
response to fluid shear stress GO:0034405 2 0.023
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.023
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.023
cell cell adhesion involved in gastrulation GO:0070586 4 0.022
Zebrafish
single organism nuclear import GO:1902593 3 0.022
taxis GO:0042330 109 0.022
Fly
macroautophagy GO:0016236 1 0.022
developmental growth involved in morphogenesis GO:0060560 86 0.022
cell proliferation in forebrain GO:0021846 3 0.022
Mouse
immune system development GO:0002520 191 0.022
Fly
regulation of cellular component size GO:0032535 30 0.022
multicellular organismal signaling GO:0035637 22 0.022
phosphatidylinositol mediated signaling GO:0048015 2 0.022
transcription from rna polymerase ii promoter GO:0006366 80 0.022
Human Mouse Fly
organelle organization GO:0006996 227 0.022
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
regulation of hydrolase activity GO:0051336 28 0.021
convergent extension involved in organogenesis GO:0060029 10 0.021
regulation of nucleoside metabolic process GO:0009118 2 0.021
positive regulation of protein complex assembly GO:0031334 2 0.021
synaptic target recognition GO:0008039 1 0.021
cellular response to external stimulus GO:0071496 2 0.021
wnt signaling pathway GO:0016055 80 0.021
Mouse
epithelial to mesenchymal transition GO:0001837 21 0.020
inner ear development GO:0048839 126 0.020
response to stress GO:0006950 263 0.020
Mouse
blood vessel morphogenesis GO:0048514 216 0.020
negative regulation of epithelial cell proliferation GO:0050680 1 0.020
cellular protein modification process GO:0006464 100 0.020
Mouse
regulation of cell growth GO:0001558 29 0.020
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.020
homeostasis of number of cells GO:0048872 62 0.020
regulation of apoptotic process GO:0042981 98 0.020
regulation of protein polymerization GO:0032271 2 0.019
ensheathment of neurons GO:0007272 18 0.019
positive regulation of signal transduction GO:0009967 56 0.019
Mouse
actin filament polymerization GO:0030041 2 0.019
insulin like growth factor receptor signaling pathway GO:0048009 4 0.019
regulation of nervous system development GO:0051960 90 0.019
regulation of carbohydrate metabolic process GO:0006109 4 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
bone morphogenesis GO:0060349 11 0.019
regulation of biosynthetic process GO:0009889 250 0.019
Human Mouse Fly
regulation of gtp catabolic process GO:0033124 2 0.019
axonal defasciculation GO:0007414 2 0.019
negative regulation of metabolic process GO:0009892 86 0.019
Human Mouse Fly
cellular response to nutrient levels GO:0031669 2 0.018
axon development GO:0061564 166 0.018
Fly
central nervous system neuron differentiation GO:0021953 74 0.018
cell migration GO:0016477 237 0.018
olfactory bulb development GO:0021772 4 0.018
positive regulation of nucleotide catabolic process GO:0030813 1 0.018
homeostatic process GO:0042592 142 0.018
cellular ketone metabolic process GO:0042180 11 0.018
gtp metabolic process GO:0046039 4 0.018
negative regulation of chromosome organization GO:2001251 1 0.017
positive regulation of signaling GO:0023056 56 0.017
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.017
Human Mouse Fly
forebrain neuron fate commitment GO:0021877 1 0.017
keratinocyte differentiation GO:0030216 0 0.017
axon guidance GO:0007411 86 0.017
Fly
regulation of cell differentiation GO:0045595 142 0.017
Mouse
retina vasculature development in camera type eye GO:0061298 2 0.017
protein dephosphorylation GO:0006470 3 0.017
reproductive process GO:0022414 40 0.017
Fly
regulation of wnt signaling pathway GO:0030111 53 0.017
Mouse
dorsal ventral pattern formation GO:0009953 125 0.017
protein complex assembly GO:0006461 30 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
germ cell migration GO:0008354 8 0.017
Fly
guanosine containing compound catabolic process GO:1901069 2 0.016
regulation of binding GO:0051098 3 0.016
regulation of protein targeting GO:1903533 2 0.016
regulation of oocyte development GO:0060281 3 0.016
nephron tubule morphogenesis GO:0072078 1 0.016
tube formation GO:0035148 25 0.016
Mouse
somitogenesis GO:0001756 87 0.016
specification of organ position GO:0010159 3 0.016
negative regulation of cell differentiation GO:0045596 46 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
tissue migration GO:0090130 37 0.015
Mouse
nitrogen compound metabolic process GO:0006807 319 0.015
Human Mouse Fly
cell morphogenesis GO:0000902 289 0.015
regulation of response to extracellular stimulus GO:0032104 1 0.015
cell projection organization GO:0030030 284 0.015
Fly
olfactory placode formation GO:0030910 1 0.015
regulation of cell activation GO:0050865 1 0.015
actin filament based process GO:0030029 64 0.015
aorta development GO:0035904 4 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
cellular component biogenesis GO:0044085 178 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
cellular response to organonitrogen compound GO:0071417 5 0.015
ovulation cycle process GO:0022602 2 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
Human Mouse Fly
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
protein polymerization GO:0051258 4 0.014
protein import GO:0017038 3 0.014
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.014
negative regulation of protein transport GO:0051224 3 0.014
ovarian follicle development GO:0001541 2 0.014
intracellular signal transduction GO:0035556 85 0.014
Mouse
regulation of behavior GO:0050795 24 0.014
cell maturation GO:0048469 23 0.014
neuron death GO:0070997 21 0.014
cranial nerve morphogenesis GO:0021602 15 0.014
positive regulation of protein polymerization GO:0032273 2 0.014
negative regulation of bmp signaling pathway GO:0030514 13 0.014
regulation of heart contraction GO:0008016 32 0.014
cell proliferation in midbrain GO:0033278 4 0.014
regulation of cytokine mediated signaling pathway GO:0001959 3 0.014
ras protein signal transduction GO:0007265 7 0.014
protein deacetylation GO:0006476 3 0.014
negative regulation of feeding behavior GO:2000252 2 0.014
multicellular organismal response to stress GO:0033555 2 0.014
canonical wnt signaling pathway GO:0060070 48 0.014
programmed cell death GO:0012501 119 0.014
blood circulation GO:0008015 87 0.014
regulation of activin receptor signaling pathway GO:0032925 5 0.014
cellular response to growth factor stimulus GO:0071363 39 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.014
anterior posterior axon guidance GO:0033564 5 0.014
regulation of cellular protein metabolic process GO:0032268 52 0.014
Mouse
purine containing compound metabolic process GO:0072521 29 0.013
regulation of rna metabolic process GO:0051252 224 0.013
Human Mouse Fly
camp biosynthetic process GO:0006171 11 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
Human Mouse
circulatory system process GO:0003013 87 0.013
myeloid cell homeostasis GO:0002262 56 0.013
skeletal muscle organ development GO:0060538 78 0.013
organelle assembly GO:0070925 110 0.013
cell death GO:0008219 121 0.013
axon midline choice point recognition GO:0016199 4 0.013
regulation of phosphate metabolic process GO:0019220 43 0.013
Mouse
skeletal muscle tissue development GO:0007519 67 0.013
multi organism process GO:0051704 134 0.013
Fly
regulation of organ morphogenesis GO:2000027 35 0.013
striated muscle cell development GO:0055002 108 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
Human Mouse Fly
convergent extension involved in axis elongation GO:0060028 26 0.013
venous blood vessel development GO:0060841 9 0.013
macromolecule deacylation GO:0098732 3 0.013
carbohydrate homeostasis GO:0033500 1 0.013
dna templated transcription initiation GO:0006352 1 0.013
pericardium development GO:0060039 1 0.013
forebrain cell migration GO:0021885 1 0.013
commissural neuron axon guidance GO:0071679 3 0.013
response to corticosteroid GO:0031960 1 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
organ regeneration GO:0031100 1 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
Mouse
epidermal cell differentiation GO:0009913 36 0.012
muscle organ development GO:0007517 101 0.012
neuron projection development GO:0031175 180 0.012
Fly
positive regulation of map kinase activity GO:0043406 3 0.012
Mouse
glial cell proliferation GO:0014009 4 0.012
lamellipodium organization GO:0097581 1 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
dorsal aorta development GO:0035907 4 0.012
negative regulation of wnt signaling pathway GO:0030178 30 0.012
glial cell migration GO:0008347 3 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
regulation of protein metabolic process GO:0051246 56 0.012
Mouse
negative regulation of intracellular transport GO:0032387 3 0.012
epidermis morphogenesis GO:0048730 4 0.012
negative regulation of cellular metabolic process GO:0031324 77 0.012
Human Mouse Fly
regulation of anatomical structure size GO:0090066 33 0.012
neuron projection guidance GO:0097485 86 0.012
Fly
establishment of protein localization to organelle GO:0072594 4 0.012
forebrain morphogenesis GO:0048853 6 0.012
negative regulation of defense response GO:0031348 2 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
Human Mouse
forebrain neuron development GO:0021884 7 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
neuron projection regeneration GO:0031102 16 0.012
forebrain regionalization GO:0021871 4 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
ventral spinal cord development GO:0021517 35 0.011
ribonucleotide biosynthetic process GO:0009260 20 0.011
neutrophil differentiation GO:0030223 6 0.011
organic acid metabolic process GO:0006082 31 0.011
response to glucocorticoid GO:0051384 1 0.011
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.011
embryonic heart tube development GO:0035050 133 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
Human Mouse
startle response GO:0001964 4 0.011
negative regulation of epithelial cell migration GO:0010633 1 0.011

zeb2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.087
nervous system disease DOID:863 0 0.023
large intestine cancer DOID:5672 0 0.021
gastrointestinal system cancer DOID:3119 0 0.021
intestinal cancer DOID:10155 0 0.021
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.021
colorectal cancer DOID:9256 0 0.021
cardiovascular system disease DOID:1287 0 0.020
epilepsy syndrome DOID:1826 0 0.013
central nervous system disease DOID:331 0 0.013
brain disease DOID:936 0 0.013
musculoskeletal system disease DOID:17 0 0.012