Danio rerio

0 known processes

zerg24

potassium voltage-gated channel zerg24

zerg24 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of muscle contraction GO:0006937 3 0.162
central nervous system development GO:0007417 387 0.135
response to chemical GO:0042221 320 0.115
negative regulation of cellular process GO:0048523 283 0.113
regulation of biological quality GO:0065008 263 0.096
negative regulation of biological process GO:0048519 304 0.087
larval development GO:0002164 2 0.085
response to stress GO:0006950 263 0.085
response to drug GO:0042493 3 0.079
nitrogen compound metabolic process GO:0006807 319 0.073
protein metabolic process GO:0019538 183 0.071
aging GO:0007568 2 0.068
regulation of multicellular organismal process GO:0051239 277 0.066
positive regulation of cytokine production GO:0001819 2 0.066
blood vessel morphogenesis GO:0048514 216 0.065
heart contraction GO:0060047 71 0.064
regulation of nitrogen compound metabolic process GO:0051171 251 0.060
blood vessel development GO:0001568 246 0.060
brain development GO:0007420 293 0.059
organic cyclic compound biosynthetic process GO:1901362 223 0.057
organic substance biosynthetic process GO:1901576 289 0.056
cellular component movement GO:0006928 335 0.053
single organism metabolic process GO:0044710 217 0.053
positive regulation of transport GO:0051050 2 0.053
regulation of striated muscle contraction GO:0006942 2 0.052
regulation of metal ion transport GO:0010959 4 0.051
regulation of cell communication GO:0010646 232 0.051
regulation of primary metabolic process GO:0080090 311 0.048
positive regulation of cellular process GO:0048522 201 0.048
ion transport GO:0006811 114 0.046
immune system development GO:0002520 191 0.046
neuron development GO:0048666 262 0.045
blood circulation GO:0008015 87 0.045
cellular nitrogen compound metabolic process GO:0034641 290 0.043
response to wounding GO:0009611 116 0.042
nucleic acid metabolic process GO:0090304 244 0.042
positive regulation of biological process GO:0048518 253 0.041
immune system process GO:0002376 241 0.041
regulation of cytokine production GO:0001817 3 0.040
locomotion GO:0040011 313 0.040
actin filament based movement GO:0030048 1 0.040
neuron differentiation GO:0030182 353 0.040
heart process GO:0003015 71 0.040
organic cyclic compound metabolic process GO:1901360 301 0.039
regulation of actin filament based movement GO:1903115 1 0.039
vasculature development GO:0001944 278 0.039
cellular amide metabolic process GO:0043603 4 0.038
signal transduction GO:0007165 455 0.038
monovalent inorganic cation transport GO:0015672 42 0.037
organonitrogen compound metabolic process GO:1901564 74 0.037
cellular response to chemical stimulus GO:0070887 157 0.037
regulation of signaling GO:0023051 235 0.037
cellular response to external stimulus GO:0071496 2 0.036
positive regulation of stress activated mapk cascade GO:0032874 3 0.035
heterocycle biosynthetic process GO:0018130 215 0.035
regulation of protein ubiquitination GO:0031396 3 0.035
regulation of signal transduction GO:0009966 225 0.034
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.034
organic acid metabolic process GO:0006082 31 0.034
sensory organ development GO:0007423 393 0.034
embryonic organ development GO:0048568 381 0.034
cellular response to biotic stimulus GO:0071216 3 0.034
cellular response to molecule of bacterial origin GO:0071219 3 0.034
biosynthetic process GO:0009058 294 0.033
cellular nitrogen compound biosynthetic process GO:0044271 218 0.033
protein secretion GO:0009306 1 0.033
regulation of blood circulation GO:1903522 32 0.033
cation transmembrane transport GO:0098655 65 0.032
circulatory system process GO:0003013 87 0.032
head development GO:0060322 303 0.032
system process GO:0003008 185 0.032
action potential GO:0001508 19 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
response to other organism GO:0051707 97 0.032
positive regulation of cell cycle GO:0045787 3 0.032
response to external stimulus GO:0009605 264 0.032
regulation of cellular amine metabolic process GO:0033238 0 0.032
regulation of heart contraction GO:0008016 32 0.031
regulation of autophagy GO:0010506 3 0.031
multicellular organismal signaling GO:0035637 22 0.031
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.031
leukocyte proliferation GO:0070661 1 0.031
small molecule metabolic process GO:0044281 77 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.030
negative regulation of protein phosphorylation GO:0001933 4 0.030
regulation of metabolic process GO:0019222 359 0.030
regulation of production of molecular mediator of immune response GO:0002700 1 0.030
heterocycle metabolic process GO:0046483 290 0.030
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.029
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.029
regulation of programmed cell death GO:0043067 101 0.029
regulation of membrane potential GO:0042391 23 0.029
lipid storage GO:0019915 1 0.029
maintenance of location GO:0051235 4 0.029
regulation of cellular metabolic process GO:0031323 320 0.029
cellular response to lipopolysaccharide GO:0071222 3 0.029
membrane repolarization GO:0086009 2 0.028
hemopoiesis GO:0030097 183 0.028
oxoacid metabolic process GO:0043436 31 0.028
cell migration GO:0016477 237 0.028
phagocytosis GO:0006909 3 0.028
amine metabolic process GO:0009308 2 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.027
response to nutrient GO:0007584 3 0.027
stem cell proliferation GO:0072089 4 0.027
nucleobase containing compound biosynthetic process GO:0034654 205 0.027
single organism transport GO:0044765 206 0.027
multicellular organism growth GO:0035264 4 0.027
cell death GO:0008219 121 0.027
cellular macromolecule metabolic process GO:0044260 391 0.027
regulation of macromolecule metabolic process GO:0060255 317 0.027
autophagy GO:0006914 4 0.027
production of molecular mediator of immune response GO:0002440 2 0.027
i kappab kinase nf kappab signaling GO:0007249 4 0.027
regulation of transcription dna templated GO:0006355 213 0.026
neurological system process GO:0050877 62 0.026
sensory perception GO:0007600 39 0.026
peptide metabolic process GO:0006518 1 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
cellular amine metabolic process GO:0044106 2 0.026
cellular component morphogenesis GO:0032989 336 0.026
regulation of apoptotic process GO:0042981 98 0.026
carboxylic acid metabolic process GO:0019752 22 0.025
cell substrate adhesion GO:0031589 4 0.025
regulation of cell activation GO:0050865 1 0.025
death GO:0016265 121 0.025
cellular response to extracellular stimulus GO:0031668 2 0.025
regulation of reactive oxygen species metabolic process GO:2000377 2 0.025
programmed cell death GO:0012501 119 0.025
cellular amino acid metabolic process GO:0006520 7 0.025
response to organic substance GO:0010033 153 0.025
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.024
regulation of protein catabolic process GO:0042176 1 0.024
regulation of rna biosynthetic process GO:2001141 213 0.024
cellular macromolecule biosynthetic process GO:0034645 224 0.024
generation of neurons GO:0048699 385 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
cellular ketone metabolic process GO:0042180 11 0.023
erythrocyte differentiation GO:0030218 54 0.023
response to glucocorticoid GO:0051384 1 0.023
positive regulation of catabolic process GO:0009896 4 0.023
rna metabolic process GO:0016070 219 0.023
regulation of system process GO:0044057 40 0.023
heart development GO:0007507 313 0.023
positive regulation of signaling GO:0023056 56 0.023
regulation of inflammatory response GO:0050727 2 0.023
establishment of localization GO:0051234 244 0.023
protein modification process GO:0036211 100 0.023
positive regulation of cell activation GO:0050867 1 0.023
inorganic cation transmembrane transport GO:0098662 50 0.023
response to carbohydrate GO:0009743 3 0.023
stem cell maintenance GO:0019827 4 0.022
inositol lipid mediated signaling GO:0048017 2 0.022
regulation of macromolecule biosynthetic process GO:0010556 225 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
protein targeting to nucleus GO:0044744 3 0.022
peptide transport GO:0015833 1 0.022
regulation of cell death GO:0010941 103 0.022
cellular protein catabolic process GO:0044257 4 0.021
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
positive regulation of jnk cascade GO:0046330 3 0.021
transcription dna templated GO:0006351 181 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
embryonic hemopoiesis GO:0035162 53 0.021
regulation of cardiac muscle contraction GO:0055117 2 0.021
mononuclear cell proliferation GO:0032943 1 0.021
gene expression GO:0010467 252 0.021
cell part morphogenesis GO:0032990 246 0.021
metal ion transport GO:0030001 58 0.021
nucleobase containing compound metabolic process GO:0006139 274 0.021
regulation of jak stat cascade GO:0046425 3 0.021
regulation of response to stimulus GO:0048583 269 0.021
macromolecule modification GO:0043412 111 0.020
angiogenesis GO:0001525 158 0.020
cellular aromatic compound metabolic process GO:0006725 295 0.020
antimicrobial humoral response GO:0019730 2 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
regulation of gene expression GO:0010468 265 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
cell morphogenesis GO:0000902 289 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
response to biotic stimulus GO:0009607 97 0.020
positive regulation of map kinase activity GO:0043406 3 0.020
tissue remodeling GO:0048771 4 0.020
b cell activation GO:0042113 2 0.020
regulation of rna metabolic process GO:0051252 224 0.019
positive regulation of neuron death GO:1901216 1 0.019
hematopoietic or lymphoid organ development GO:0048534 191 0.019
neuromast development GO:0048884 46 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
somatic muscle development GO:0007525 4 0.019
homeostatic process GO:0042592 142 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
cellular protein modification process GO:0006464 100 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.019
multi organism process GO:0051704 134 0.019
negative regulation of kinase activity GO:0033673 4 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
cellular biosynthetic process GO:0044249 286 0.019
nucleic acid templated transcription GO:0097659 181 0.019
cellular response to starvation GO:0009267 1 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
regulation of developmental process GO:0050793 247 0.018
erythrocyte homeostasis GO:0034101 55 0.018
muscle contraction GO:0006936 18 0.018
stem cell division GO:0017145 1 0.018
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.018
protein heterooligomerization GO:0051291 1 0.018
response to corticosteroid GO:0031960 1 0.018
cellular protein metabolic process GO:0044267 129 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
response to external biotic stimulus GO:0043207 97 0.018
nitric oxide metabolic process GO:0046209 2 0.018
regulation of cell shape GO:0008360 1 0.018
single organism nuclear import GO:1902593 3 0.018
protein import GO:0017038 3 0.018
cellular response to nutrient levels GO:0031669 2 0.018
gastrulation GO:0007369 208 0.017
positive regulation of secretion GO:0051047 1 0.017
eye development GO:0001654 277 0.017
spinal cord development GO:0021510 46 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
regulation of organ growth GO:0046620 3 0.017
mitochondrion organization GO:0007005 4 0.017
gtp catabolic process GO:0006184 2 0.017
regulation of multicellular organism growth GO:0040014 4 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
somite development GO:0061053 96 0.017
nuclear import GO:0051170 3 0.017
regulation of hormone secretion GO:0046883 2 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
myeloid cell homeostasis GO:0002262 56 0.017
guanosine containing compound catabolic process GO:1901069 2 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
nuclear transport GO:0051169 4 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
hormone secretion GO:0046879 2 0.016
negative regulation of cytokine production GO:0001818 1 0.016
regulation of reproductive process GO:2000241 4 0.016
cation homeostasis GO:0055080 33 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.016
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.016
female gonad development GO:0008585 4 0.016
lymphocyte proliferation GO:0046651 1 0.016
female sex differentiation GO:0046660 4 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
regulation of response to biotic stimulus GO:0002831 2 0.016
nitric oxide biosynthetic process GO:0006809 2 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.015
cellular response to organic substance GO:0071310 105 0.015
cell projection organization GO:0030030 284 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.015
cellular response to hypoxia GO:0071456 1 0.015
reactive nitrogen species metabolic process GO:2001057 0 0.015
somitogenesis GO:0001756 87 0.015
response to hexose GO:0009746 3 0.015
alpha amino acid metabolic process GO:1901605 3 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
actin mediated cell contraction GO:0070252 1 0.015
phagocytosis engulfment GO:0006911 1 0.015
regulation of biosynthetic process GO:0009889 250 0.015
negative regulation of cellular catabolic process GO:0031330 3 0.015
intracellular signal transduction GO:0035556 85 0.015
myeloid cell differentiation GO:0030099 86 0.015
chordate embryonic development GO:0043009 271 0.015
negative regulation of secretion by cell GO:1903531 2 0.015
cellular response to xenobiotic stimulus GO:0071466 35 0.015
apoptotic process GO:0006915 116 0.014
positive regulation of immune effector process GO:0002699 3 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
transmembrane transport GO:0055085 120 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
regulation of tube size GO:0035150 2 0.014
neuron neuron synaptic transmission GO:0007270 1 0.014
single organism localization GO:1902578 225 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
determination of bilateral symmetry GO:0009855 204 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
regulation of protein transport GO:0051223 3 0.014
transport GO:0006810 220 0.014
macroautophagy GO:0016236 1 0.014
regulation of leukocyte mediated immunity GO:0002703 1 0.014
gtp metabolic process GO:0046039 4 0.014
regulation of response to stress GO:0080134 36 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
regulation of binding GO:0051098 3 0.014
negative regulation of catabolic process GO:0009895 3 0.014
synaptic transmission cholinergic GO:0007271 4 0.014
muscle tissue development GO:0060537 110 0.014
reactive oxygen species metabolic process GO:0072593 6 0.014
potassium ion transport GO:0006813 10 0.014
response to glucose GO:0009749 3 0.014
camera type eye development GO:0043010 222 0.013
response to alkaloid GO:0043279 2 0.013
homeostasis of number of cells GO:0048872 62 0.013
response to bacterium GO:0009617 58 0.013
digestive tract morphogenesis GO:0048546 231 0.013
protein localization to nucleus GO:0034504 3 0.013
localization of cell GO:0051674 244 0.013
regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307 1 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
post embryonic organ development GO:0048569 4 0.013
compound eye development GO:0048749 2 0.013
cell projection morphogenesis GO:0048858 244 0.013
establishment of protein localization to organelle GO:0072594 4 0.013
neuron projection morphogenesis GO:0048812 161 0.013
protein import into nucleus GO:0006606 3 0.013
positive regulation of cell communication GO:0010647 56 0.013
immunoglobulin mediated immune response GO:0016064 3 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
inorganic ion transmembrane transport GO:0098660 57 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
organelle organization GO:0006996 227 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
sensory system development GO:0048880 76 0.013
phosphatidylinositol mediated signaling GO:0048015 2 0.013
positive regulation of neuron apoptotic process GO:0043525 1 0.013
regulation of ion transmembrane transport GO:0034765 18 0.013
cell motility GO:0048870 244 0.013
b cell mediated immunity GO:0019724 3 0.012
regulation of circadian rhythm GO:0042752 4 0.012
fertilization GO:0009566 3 0.012
muscle system process GO:0003012 20 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.012
muscle organ development GO:0007517 101 0.012
striated muscle cell differentiation GO:0051146 129 0.012
muscle structure development GO:0061061 196 0.012
inner ear development GO:0048839 126 0.012
behavior GO:0007610 74 0.012
axonogenesis GO:0007409 152 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
protein stabilization GO:0050821 2 0.012
lateral line development GO:0048882 66 0.012
cell proliferation GO:0008283 80 0.012
positive regulation of metabolic process GO:0009893 108 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.012
regulation of cell substrate adhesion GO:0010810 1 0.012
specification of symmetry GO:0009799 204 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.012
regulation of blood vessel size GO:0050880 2 0.012
regulation of protein complex assembly GO:0043254 3 0.012
gland development GO:0048732 143 0.011
immune response GO:0006955 28 0.011
cellular response to oxygen levels GO:0071453 1 0.011
response to monosaccharide GO:0034284 3 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
cardiac muscle cell contraction GO:0086003 1 0.011
neuroblast proliferation GO:0007405 2 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
adult behavior GO:0030534 2 0.011
regulation of blood pressure GO:0008217 1 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
astrocyte differentiation GO:0048708 1 0.011
sensory perception of pain GO:0019233 1 0.011
protein acylation GO:0043543 3 0.011
lateral line system development GO:0048925 76 0.011
response to lipid GO:0033993 60 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
muscle cell differentiation GO:0042692 139 0.011
negative regulation of defense response GO:0031348 2 0.011
tube morphogenesis GO:0035239 349 0.011
negative regulation of cell death GO:0060548 60 0.011
regulation of protein targeting GO:1903533 2 0.011
sensory perception of mechanical stimulus GO:0050954 16 0.011
digestive tract development GO:0048565 265 0.011
positive regulation of leukocyte mediated immunity GO:0002705 1 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
positive regulation of gliogenesis GO:0014015 2 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
lateral inhibition GO:0046331 1 0.011
negative regulation of myeloid cell differentiation GO:0045638 1 0.011
negative regulation of protein transport GO:0051224 3 0.011
hormone transport GO:0009914 2 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
convergent extension GO:0060026 118 0.011
liver development GO:0001889 96 0.011
negative regulation of secretion GO:0051048 2 0.011
water homeostasis GO:0030104 4 0.011
regulation of membrane repolarization GO:0060306 1 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
cellular response to stress GO:0033554 62 0.010
phosphorus metabolic process GO:0006793 109 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
negative regulation of metabolic process GO:0009892 86 0.010
regulation of response to nutrient levels GO:0032107 1 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
cognition GO:0050890 1 0.010
sensory perception of sound GO:0007605 9 0.010
hematopoietic stem cell differentiation GO:0060218 20 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
positive regulation of multi organism process GO:0043902 3 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
cardiac conduction GO:0061337 3 0.010
response to ketone GO:1901654 1 0.010
g1 s transition of mitotic cell cycle GO:0000082 1 0.010
response to transition metal nanoparticle GO:1990267 28 0.010
positive regulation of dna metabolic process GO:0051054 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
growth GO:0040007 174 0.010
rna biosynthetic process GO:0032774 181 0.010
cell matrix adhesion GO:0007160 4 0.010
positive regulation of macromolecule metabolic process GO:0010604 93 0.010
hematopoietic progenitor cell differentiation GO:0002244 23 0.010
carbohydrate homeostasis GO:0033500 1 0.010
cardiac muscle contraction GO:0060048 6 0.010

zerg24 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
disease of metabolism DOID:0014667 0 0.019
nervous system disease DOID:863 0 0.015
musculoskeletal system disease DOID:17 0 0.012
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.010