Danio rerio

0 known processes

zfand2a

zinc finger, AN1-type domain 2A

(Aliases: zgc:77923,MGC66295,zgc:66295)

zfand2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular protein catabolic process GO:0044257 4 0.226
ubiquitin dependent protein catabolic process GO:0006511 3 0.175
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.174
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.169
modification dependent protein catabolic process GO:0019941 3 0.120
protein polyubiquitination GO:0000209 4 0.105
positive regulation of catabolic process GO:0009896 4 0.090
modification dependent macromolecule catabolic process GO:0043632 3 0.089
signal transduction GO:0007165 455 0.087
proteasomal protein catabolic process GO:0010498 2 0.087
microtubule organizing center organization GO:0031023 1 0.084
centrosome cycle GO:0007098 1 0.078
positive regulation of cellular catabolic process GO:0031331 3 0.074
centrosome organization GO:0051297 1 0.074
regulation of signaling GO:0023051 235 0.069
i kappab kinase nf kappab signaling GO:0007249 4 0.063
regulation of cell communication GO:0010646 232 0.060
meiotic nuclear division GO:0007126 4 0.060
aging GO:0007568 2 0.058
intracellular signal transduction GO:0035556 85 0.058
regulation of signal transduction GO:0009966 225 0.051
regulation of response to stimulus GO:0048583 269 0.051
response to stress GO:0006950 263 0.051
cell cycle g1 s phase transition GO:0044843 1 0.050
organelle fusion GO:0048284 3 0.049
maintenance of location GO:0051235 4 0.049
protein metabolic process GO:0019538 183 0.048
embryo development ending in birth or egg hatching GO:0009792 271 0.047
regulation of protein catabolic process GO:0042176 1 0.047
response to uv GO:0009411 3 0.045
meiotic cell cycle process GO:1903046 3 0.045
positive regulation of biological process GO:0048518 253 0.043
single organism membrane fusion GO:0044801 2 0.041
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.040
lipid storage GO:0019915 1 0.039
regulation of cellular protein catabolic process GO:1903362 1 0.038
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.038
negative regulation of cellular process GO:0048523 283 0.038
organelle organization GO:0006996 227 0.038
regulation of cell activation GO:0050865 1 0.036
mitochondrion organization GO:0007005 4 0.036
regulation of nucleoside metabolic process GO:0009118 2 0.035
regulation of cytokine production GO:0001817 3 0.035
nitrogen compound metabolic process GO:0006807 319 0.034
regulation of metabolic process GO:0019222 359 0.034
regulation of cellular metabolic process GO:0031323 320 0.034
guanosine containing compound metabolic process GO:1901068 4 0.034
regulation of programmed cell death GO:0043067 101 0.033
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.033
determination of bilateral symmetry GO:0009855 204 0.032
female gonad development GO:0008585 4 0.032
mitotic dna damage checkpoint GO:0044773 4 0.031
mitotic dna integrity checkpoint GO:0044774 4 0.031
apoptotic process GO:0006915 116 0.031
positive regulation of transport GO:0051050 2 0.031
larval development GO:0002164 2 0.030
nuclear transport GO:0051169 4 0.030
transport GO:0006810 220 0.030
establishment of protein localization to organelle GO:0072594 4 0.029
regulation of macromolecule metabolic process GO:0060255 317 0.029
meiosis i GO:0007127 1 0.029
g1 s transition of mitotic cell cycle GO:0000082 1 0.028
regulation of primary metabolic process GO:0080090 311 0.028
regulation of transcription dna templated GO:0006355 213 0.028
cellular protein metabolic process GO:0044267 129 0.028
female sex differentiation GO:0046660 4 0.028
nucleocytoplasmic transport GO:0006913 4 0.027
membrane fusion GO:0061025 2 0.027
autophagy GO:0006914 4 0.027
gtp catabolic process GO:0006184 2 0.027
negative regulation of cell communication GO:0010648 96 0.027
multicellular organism growth GO:0035264 4 0.026
positive regulation of cellular process GO:0048522 201 0.026
peptide transport GO:0015833 1 0.026
nucleobase containing compound metabolic process GO:0006139 274 0.026
positive regulation of map kinase activity GO:0043406 3 0.026
heterocycle metabolic process GO:0046483 290 0.026
cell death GO:0008219 121 0.026
regulation of biosynthetic process GO:0009889 250 0.025
cellular response to dna damage stimulus GO:0006974 24 0.025
single organism transport GO:0044765 206 0.025
guanosine containing compound catabolic process GO:1901069 2 0.025
positive regulation of nucleoside metabolic process GO:0045979 1 0.025
negative regulation of biological process GO:0048519 304 0.024
protein k48 linked ubiquitination GO:0070936 1 0.024
regulation of multicellular organism growth GO:0040014 4 0.024
regulation of purine nucleotide catabolic process GO:0033121 2 0.024
hematopoietic or lymphoid organ development GO:0048534 191 0.024
homeostatic process GO:0042592 142 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
positive regulation of gtp catabolic process GO:0033126 1 0.024
double strand break repair GO:0006302 3 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.024
embryonic organ development GO:0048568 381 0.024
cell cycle GO:0007049 93 0.023
positive regulation of cytokine production GO:0001819 2 0.023
death GO:0016265 121 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
proteolysis GO:0006508 38 0.023
gtp metabolic process GO:0046039 4 0.023
regulation of gene expression GO:0010468 265 0.023
development of primary female sexual characteristics GO:0046545 4 0.022
positive regulation of apoptotic signaling pathway GO:2001235 1 0.022
amine metabolic process GO:0009308 2 0.022
regulation of gtp catabolic process GO:0033124 2 0.022
regulation of protein complex assembly GO:0043254 3 0.022
organic cyclic compound metabolic process GO:1901360 301 0.022
kidney development GO:0001822 92 0.022
regulation of binding GO:0051098 3 0.022
nuclear export GO:0051168 1 0.022
positive regulation of protein complex assembly GO:0031334 2 0.021
cytokinesis GO:0000910 3 0.021
negative regulation of signaling GO:0023057 96 0.021
hemopoiesis GO:0030097 183 0.021
aromatic compound biosynthetic process GO:0019438 217 0.021
regulation of intracellular signal transduction GO:1902531 57 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.021
meiotic chromosome segregation GO:0045132 3 0.021
negative regulation of nuclear division GO:0051784 3 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
single organism localization GO:1902578 225 0.020
specification of symmetry GO:0009799 204 0.020
cellular amine metabolic process GO:0044106 2 0.020
establishment of localization GO:0051234 244 0.020
macromolecule biosynthetic process GO:0009059 227 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.020
cellular response to starvation GO:0009267 1 0.020
gene expression GO:0010467 252 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
ovulation cycle GO:0042698 2 0.020
cellular component movement GO:0006928 335 0.020
positive regulation of cell cycle GO:0045787 3 0.020
nuclear import GO:0051170 3 0.020
regulation of nucleotide catabolic process GO:0030811 2 0.020
regulation of reproductive process GO:2000241 4 0.019
morphogenesis of an epithelium GO:0002009 333 0.019
head development GO:0060322 303 0.019
negative regulation of mapk cascade GO:0043409 4 0.019
rna biosynthetic process GO:0032774 181 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
positive regulation of metabolic process GO:0009893 108 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
regulation of response to stress GO:0080134 36 0.019
regulation of hormone secretion GO:0046883 2 0.019
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
immune system development GO:0002520 191 0.019
regulation of gtpase activity GO:0043087 2 0.019
single fertilization GO:0007338 3 0.018
positive regulation of immune effector process GO:0002699 3 0.018
stem cell proliferation GO:0072089 4 0.018
single organism nuclear import GO:1902593 3 0.018
signal transduction in absence of ligand GO:0038034 1 0.018
regulation of metal ion transport GO:0010959 4 0.018
cellular nitrogen compound metabolic process GO:0034641 290 0.018
programmed cell death GO:0012501 119 0.018
cellular response to topologically incorrect protein GO:0035967 2 0.018
b cell activation GO:0042113 2 0.018
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.018
phagocytosis GO:0006909 3 0.017
brain development GO:0007420 293 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
positive regulation of gtpase activity GO:0043547 1 0.017
regulation of apoptotic process GO:0042981 98 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
cellular response to external stimulus GO:0071496 2 0.017
regulation of protein transport GO:0051223 3 0.017
renal system development GO:0072001 94 0.017
cell cycle process GO:0022402 53 0.017
regulation of ph GO:0006885 3 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
developmental programmed cell death GO:0010623 4 0.017
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.017
cell migration GO:0016477 237 0.017
nucleic acid metabolic process GO:0090304 244 0.016
protein import GO:0017038 3 0.016
central nervous system development GO:0007417 387 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
determination of left right symmetry GO:0007368 179 0.016
regulation of biological quality GO:0065008 263 0.016
protein localization to plasma membrane GO:0072659 1 0.016
spindle assembly GO:0051225 2 0.016
vasculature development GO:0001944 278 0.016
cellular protein modification process GO:0006464 100 0.016
system process GO:0003008 185 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
sensory organ development GO:0007423 393 0.016
single organism metabolic process GO:0044710 217 0.016
biosynthetic process GO:0009058 294 0.016
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.015
protein import into nucleus GO:0006606 3 0.015
regulation of cell death GO:0010941 103 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
transcription dna templated GO:0006351 181 0.015
fertilization GO:0009566 3 0.015
urogenital system development GO:0001655 97 0.015
response to topologically incorrect protein GO:0035966 2 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
locomotor rhythm GO:0045475 3 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
positive regulation of secretion GO:0051047 1 0.015
regulation of protein metabolic process GO:0051246 56 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
cellular response to radiation GO:0071478 4 0.015
negative regulation of mitosis GO:0045839 3 0.015
glucose homeostasis GO:0042593 1 0.015
rna metabolic process GO:0016070 219 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
negative regulation of map kinase activity GO:0043407 2 0.015
golgi vesicle transport GO:0048193 3 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
negative regulation of apoptotic process GO:0043066 55 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
negative regulation of signal transduction GO:0009968 94 0.014
tissue remodeling GO:0048771 4 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.014
spindle assembly involved in mitosis GO:0090307 1 0.014
regulation of intracellular ph GO:0051453 1 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
b cell differentiation GO:0030183 1 0.014
mitotic cell cycle GO:0000278 64 0.014
endosome organization GO:0007032 2 0.014
lateral inhibition GO:0046331 1 0.014
negative regulation of secretion by cell GO:1903531 2 0.014
phosphorus metabolic process GO:0006793 109 0.014
response to nutrient GO:0007584 3 0.014
regionalization GO:0003002 274 0.013
leukocyte proliferation GO:0070661 1 0.013
adult behavior GO:0030534 2 0.013
atp catabolic process GO:0006200 4 0.013
single organism organelle organization GO:1902589 199 0.013
inositol lipid mediated signaling GO:0048017 2 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
intrinsic apoptotic signaling pathway GO:0097193 20 0.013
positive regulation of lipid metabolic process GO:0045834 1 0.013
transmembrane transport GO:0055085 120 0.013
positive regulation of cell activation GO:0050867 1 0.013
regulation of protein targeting GO:1903533 2 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
protein secretion GO:0009306 1 0.013
cellular component assembly GO:0022607 170 0.013
primary neural tube formation GO:0014020 1 0.013
positive regulation of signal transduction GO:0009967 56 0.013
regulation of cell cycle GO:0051726 52 0.013
regulation of response to cytokine stimulus GO:0060759 3 0.013
mitotic recombination GO:0006312 2 0.013
negative regulation of cytokine production GO:0001818 1 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
regulation of molecular function GO:0065009 70 0.013
telomere organization GO:0032200 1 0.013
positive regulation of neuron death GO:1901216 1 0.013
protein modification process GO:0036211 100 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
cellular biosynthetic process GO:0044249 286 0.013
telomere maintenance GO:0000723 1 0.013
positive regulation of inflammatory response GO:0050729 1 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
cellular localization GO:0051641 97 0.013
mitotic cell cycle process GO:1903047 48 0.013
cell death in response to oxidative stress GO:0036473 2 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
regulation of inflammatory response GO:0050727 2 0.013
er nucleus signaling pathway GO:0006984 2 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
secondary metabolic process GO:0019748 3 0.013
compound eye development GO:0048749 2 0.013
oxoacid metabolic process GO:0043436 31 0.013
b cell mediated immunity GO:0019724 3 0.012
response to drug GO:0042493 3 0.012
regulation of rna metabolic process GO:0051252 224 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
positive regulation of neuron apoptotic process GO:0043525 1 0.012
steroid hormone secretion GO:0035929 1 0.012
organic substance biosynthetic process GO:1901576 289 0.012
cell matrix adhesion GO:0007160 4 0.012
macromolecule modification GO:0043412 111 0.012
cellular response to nutrient levels GO:0031669 2 0.012
eye development GO:0001654 277 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
immune response GO:0006955 28 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of organ growth GO:0046620 3 0.012
microtubule cytoskeleton organization GO:0000226 33 0.012
cell cycle arrest GO:0007050 1 0.012
cellular transition metal ion homeostasis GO:0046916 3 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
endosomal transport GO:0016197 2 0.012
hormone transport GO:0009914 2 0.012
immune system process GO:0002376 241 0.012
regulation of cellular ph GO:0030641 1 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
apoptotic process involved in development GO:1902742 2 0.012
glial cell migration GO:0008347 3 0.012
interspecies interaction between organisms GO:0044419 4 0.012
catecholamine metabolic process GO:0006584 2 0.012
rna localization GO:0006403 4 0.012
protein localization to nucleus GO:0034504 3 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
positive regulation of striated muscle tissue development GO:0045844 1 0.012
ovarian follicle development GO:0001541 2 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
carbohydrate homeostasis GO:0033500 1 0.012
negative regulation of intracellular signal transduction GO:1902532 22 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
protein targeting to nucleus GO:0044744 3 0.012
immunoglobulin mediated immune response GO:0016064 3 0.012
locomotion GO:0040011 313 0.012
hormone secretion GO:0046879 2 0.012
protein homooligomerization GO:0051260 3 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
negative regulation of response to cytokine stimulus GO:0060761 2 0.012
lymphocyte proliferation GO:0046651 1 0.012
nephron morphogenesis GO:0072028 2 0.011
negative regulation of cell death GO:0060548 60 0.011
response to fluid shear stress GO:0034405 2 0.011
ion transmembrane transport GO:0034220 91 0.011
cellular component morphogenesis GO:0032989 336 0.011
organelle assembly GO:0070925 110 0.011
small molecule metabolic process GO:0044281 77 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
response to unfolded protein GO:0006986 2 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
gland development GO:0048732 143 0.011
tube morphogenesis GO:0035239 349 0.011
regulation of catalytic activity GO:0050790 55 0.011
apoptotic signaling pathway GO:0097190 23 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
regulation of mitochondrion organization GO:0010821 1 0.011
recombinational repair GO:0000725 1 0.011
protein polymerization GO:0051258 4 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
cellular component disassembly GO:0022411 1 0.011
protein acetylation GO:0006473 2 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
positive regulation of muscle organ development GO:0048636 1 0.011
cell substrate adhesion GO:0031589 4 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
mononuclear cell proliferation GO:0032943 1 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
localization of cell GO:0051674 244 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
microtubule based process GO:0007017 60 0.011
response to radiation GO:0009314 51 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
stem cell division GO:0017145 1 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
heart morphogenesis GO:0003007 156 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.011
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.011
multi organism cellular process GO:0044764 2 0.011
regulation of mitotic cell cycle GO:0007346 25 0.011
cell cell recognition GO:0009988 1 0.011
protein acylation GO:0043543 3 0.011
calcium ion import GO:0070509 4 0.011
endocrine hormone secretion GO:0060986 2 0.011
entrainment of circadian clock GO:0009649 2 0.010
oligopeptide transport GO:0006857 1 0.010
response to glucocorticoid GO:0051384 1 0.010
camera type eye development GO:0043010 222 0.010
cytoskeleton organization GO:0007010 96 0.010
cellular ketone metabolic process GO:0042180 11 0.010
negative regulation of reproductive process GO:2000242 3 0.010
establishment of localization in cell GO:0051649 77 0.010
negative regulation of multi organism process GO:0043901 3 0.010
response to ketone GO:1901654 1 0.010
catechol containing compound metabolic process GO:0009712 2 0.010
heart looping GO:0001947 94 0.010
multi organism process GO:0051704 134 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
mitochondrial transport GO:0006839 2 0.010
heart development GO:0007507 313 0.010
nik nf kappab signaling GO:0038061 1 0.010
cellular response to stress GO:0033554 62 0.010
osteoclast differentiation GO:0030316 1 0.010
regulation of circadian rhythm GO:0042752 4 0.010
regulation of organelle assembly GO:1902115 4 0.010
regulation of stem cell differentiation GO:2000736 4 0.010

zfand2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
musculoskeletal system disease DOID:17 0 0.026
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.015
nervous system disease DOID:863 0 0.011
disease of metabolism DOID:0014667 0 0.011
muscular disease DOID:0080000 0 0.010