Danio rerio

8 known processes

zgc:103580

zgc:103580

(Aliases: saa)

zgc:103580 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.111
immune system process GO:0002376 241 0.101
nuclear transport GO:0051169 4 0.077
single organism metabolic process GO:0044710 217 0.076
cellular nitrogen compound metabolic process GO:0034641 290 0.070
regulation of nucleocytoplasmic transport GO:0046822 2 0.068
response to chemical GO:0042221 320 0.064
proteasomal protein catabolic process GO:0010498 2 0.057
nitrogen compound metabolic process GO:0006807 319 0.056
negative regulation of cellular process GO:0048523 283 0.055
ubiquitin dependent protein catabolic process GO:0006511 3 0.054
positive regulation of transport GO:0051050 2 0.052
organic acid metabolic process GO:0006082 31 0.050
regulation of cytokine production GO:0001817 3 0.049
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.048
multicellular organism growth GO:0035264 4 0.048
regulation of multicellular organism growth GO:0040014 4 0.048
response to amino acid GO:0043200 2 0.048
cellular amino acid metabolic process GO:0006520 7 0.046
regulation of cellular amino acid metabolic process GO:0006521 0 0.045
establishment of protein localization to organelle GO:0072594 4 0.044
regulation of cellular amine metabolic process GO:0033238 0 0.043
cellular amine metabolic process GO:0044106 2 0.042
amine metabolic process GO:0009308 2 0.042
modification dependent macromolecule catabolic process GO:0043632 3 0.041
vasculature development GO:0001944 278 0.041
cellular ketone metabolic process GO:0042180 11 0.040
biosynthetic process GO:0009058 294 0.040
regulation of biological quality GO:0065008 263 0.039
nucleocytoplasmic transport GO:0006913 4 0.039
single organism transport GO:0044765 206 0.039
cellular response to chemical stimulus GO:0070887 157 0.039
regulation of binding GO:0051098 3 0.038
oxoacid metabolic process GO:0043436 31 0.037
production of molecular mediator of immune response GO:0002440 2 0.036
regulation of meiotic cell cycle GO:0051445 1 0.035
centrosome organization GO:0051297 1 0.035
meiotic nuclear division GO:0007126 4 0.035
modification dependent protein catabolic process GO:0019941 3 0.035
phagocytosis GO:0006909 3 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.035
protein metabolic process GO:0019538 183 0.034
cellular protein catabolic process GO:0044257 4 0.034
defense response GO:0006952 47 0.034
regulation of inflammatory response GO:0050727 2 0.033
nucleobase containing compound metabolic process GO:0006139 274 0.033
positive regulation of cellular process GO:0048522 201 0.033
regulation of protein complex assembly GO:0043254 3 0.033
hormone biosynthetic process GO:0042446 3 0.033
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.033
regulation of cytoplasmic transport GO:1903649 4 0.033
small molecule metabolic process GO:0044281 77 0.033
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.033
regionalization GO:0003002 274 0.032
regulation of response to stimulus GO:0048583 269 0.032
positive regulation of biological process GO:0048518 253 0.032
regulation of metabolic process GO:0019222 359 0.032
regulation of cellular ketone metabolic process GO:0010565 7 0.030
establishment of localization GO:0051234 244 0.030
cellular component assembly involved in morphogenesis GO:0010927 107 0.030
regulation of cell death GO:0010941 103 0.030
dorsal ventral pattern formation GO:0009953 125 0.030
glucose homeostasis GO:0042593 1 0.029
protein acetylation GO:0006473 2 0.029
response to other organism GO:0051707 97 0.029
negative regulation of biological process GO:0048519 304 0.029
internal protein amino acid acetylation GO:0006475 2 0.029
stem cell proliferation GO:0072089 4 0.029
cellular component assembly GO:0022607 170 0.029
system process GO:0003008 185 0.029
single organism localization GO:1902578 225 0.028
positive regulation of cytokine production GO:0001819 2 0.028
regulation of protein targeting GO:1903533 2 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
heterocycle metabolic process GO:0046483 290 0.028
aging GO:0007568 2 0.028
hematopoietic or lymphoid organ development GO:0048534 191 0.028
interspecies interaction between organisms GO:0044419 4 0.027
embryo development ending in birth or egg hatching GO:0009792 271 0.027
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.027
regulation of synapse organization GO:0050807 3 0.027
positive regulation of cell cycle GO:0045787 3 0.027
multi organism process GO:0051704 134 0.026
regulation of cell shape GO:0008360 1 0.026
organic cyclic compound metabolic process GO:1901360 301 0.026
regulation of stem cell proliferation GO:0072091 2 0.026
growth GO:0040007 174 0.026
positive regulation of myeloid cell differentiation GO:0045639 2 0.025
regulation of protein import into nucleus GO:0042306 2 0.025
post embryonic organ development GO:0048569 4 0.025
positive regulation of protein complex assembly GO:0031334 2 0.025
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.025
cellular component morphogenesis GO:0032989 336 0.025
single organism nuclear import GO:1902593 3 0.024
microtubule organizing center organization GO:0031023 1 0.024
immune system development GO:0002520 191 0.024
protein import into nucleus GO:0006606 3 0.024
maintenance of location GO:0051235 4 0.024
positive regulation of immune effector process GO:0002699 3 0.024
muscle structure development GO:0061061 196 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.024
regulation of cell activation GO:0050865 1 0.024
carboxylic acid metabolic process GO:0019752 22 0.024
protein targeting to nucleus GO:0044744 3 0.024
hatching GO:0035188 4 0.023
regulation of mrna splicing via spliceosome GO:0048024 3 0.023
regulation of signal transduction GO:0009966 225 0.023
camera type eye development GO:0043010 222 0.023
response to external biotic stimulus GO:0043207 97 0.023
regulation of cellular metabolic process GO:0031323 320 0.023
vacuolar transport GO:0007034 2 0.023
positive regulation of cytoskeleton organization GO:0051495 3 0.023
response to drug GO:0042493 3 0.023
regulation of chromosome segregation GO:0051983 1 0.022
protein import GO:0017038 3 0.022
transport GO:0006810 220 0.022
protein heterooligomerization GO:0051291 1 0.022
negative regulation of defense response GO:0031348 2 0.022
b cell activation GO:0042113 2 0.022
response to biotic stimulus GO:0009607 97 0.022
adult behavior GO:0030534 2 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
cellular response to organic substance GO:0071310 105 0.022
protein polymerization GO:0051258 4 0.022
regulation of transcription dna templated GO:0006355 213 0.021
liver development GO:0001889 96 0.021
programmed cell death GO:0012501 119 0.021
organelle organization GO:0006996 227 0.021
cellular component biogenesis GO:0044085 178 0.021
regulation of developmental process GO:0050793 247 0.021
cellular macromolecule metabolic process GO:0044260 391 0.021
bmp signaling pathway GO:0030509 52 0.021
single organism organelle organization GO:1902589 199 0.021
regulation of protein localization to nucleus GO:1900180 2 0.021
response to external stimulus GO:0009605 264 0.021
regulation of signaling GO:0023051 235 0.020
digestive system development GO:0055123 289 0.020
localization of cell GO:0051674 244 0.020
multi organism cellular process GO:0044764 2 0.020
carbohydrate homeostasis GO:0033500 1 0.020
regulation of synapse assembly GO:0051963 3 0.020
epithelial cell morphogenesis GO:0003382 2 0.020
spermatid development GO:0007286 2 0.020
lamellipodium assembly GO:0030032 1 0.020
protein localization to nucleus GO:0034504 3 0.020
internal peptidyl lysine acetylation GO:0018393 2 0.020
cellular component movement GO:0006928 335 0.020
cell projection organization GO:0030030 284 0.020
viral process GO:0016032 1 0.020
hemopoiesis GO:0030097 183 0.020
cellular aromatic compound metabolic process GO:0006725 295 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
phagocytosis engulfment GO:0006911 1 0.020
response to antibiotic GO:0046677 1 0.019
cellular response to estrogen stimulus GO:0071391 24 0.019
regulation of protein polymerization GO:0032271 2 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
regulation of reproductive process GO:2000241 4 0.019
immunoglobulin production GO:0002377 1 0.019
i kappab kinase nf kappab signaling GO:0007249 4 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
cell migration GO:0016477 237 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
regulation of stem cell differentiation GO:2000736 4 0.018
regulation of reactive oxygen species metabolic process GO:2000377 2 0.018
chordate embryonic development GO:0043009 271 0.018
cytokinesis GO:0000910 3 0.018
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.018
regulation of production of molecular mediator of immune response GO:0002700 1 0.018
tissue remodeling GO:0048771 4 0.018
cell projection morphogenesis GO:0048858 244 0.018
regulation of sodium ion transport GO:0002028 2 0.018
locomotion GO:0040011 313 0.018
regulation of primary metabolic process GO:0080090 311 0.018
mitochondrion organization GO:0007005 4 0.018
organic substance transport GO:0071702 58 0.018
endoplasmic reticulum unfolded protein response GO:0030968 2 0.018
spermatid differentiation GO:0048515 2 0.018
establishment of protein localization to plasma membrane GO:0090002 1 0.018
gtp metabolic process GO:0046039 4 0.018
blood circulation GO:0008015 87 0.018
blood vessel morphogenesis GO:0048514 216 0.017
actin polymerization or depolymerization GO:0008154 2 0.017
response to stress GO:0006950 263 0.017
cellular amide metabolic process GO:0043603 4 0.017
response to organic cyclic compound GO:0014070 51 0.017
regulation of protein transport GO:0051223 3 0.017
meiotic cell cycle process GO:1903046 3 0.017
negative regulation of catabolic process GO:0009895 3 0.017
gene expression GO:0010467 252 0.017
epithelial cell differentiation GO:0030855 116 0.017
cell aging GO:0007569 2 0.017
cognition GO:0050890 1 0.017
cell surface receptor signaling pathway GO:0007166 325 0.017
sensory organ development GO:0007423 393 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
cellular response to stress GO:0033554 62 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.017
nuclear import GO:0051170 3 0.017
determination of bilateral symmetry GO:0009855 204 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
regulation of wound healing GO:0061041 2 0.017
regulation of metal ion transport GO:0010959 4 0.017
hepaticobiliary system development GO:0061008 98 0.017
female sex differentiation GO:0046660 4 0.016
regulation of gtpase activity GO:0043087 2 0.016
positive regulation of signaling GO:0023056 56 0.016
positive regulation of catabolic process GO:0009896 4 0.016
protein acylation GO:0043543 3 0.016
stem cell maintenance GO:0019827 4 0.016
positive regulation of leukocyte mediated immunity GO:0002705 1 0.016
regulation of rna metabolic process GO:0051252 224 0.016
immunoglobulin mediated immune response GO:0016064 3 0.016
organelle assembly GO:0070925 110 0.016
embryonic skeletal system morphogenesis GO:0048704 93 0.016
regulation of leukocyte mediated immunity GO:0002703 1 0.016
meiotic chromosome segregation GO:0045132 3 0.016
gtp catabolic process GO:0006184 2 0.016
specification of symmetry GO:0009799 204 0.016
lysosomal transport GO:0007041 2 0.016
neuroblast proliferation GO:0007405 2 0.015
myeloid cell development GO:0061515 32 0.015
cell death GO:0008219 121 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
nuclear envelope organization GO:0006998 2 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
muscle cell differentiation GO:0042692 139 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
response to alkaloid GO:0043279 2 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
protein stabilization GO:0050821 2 0.015
response to topologically incorrect protein GO:0035966 2 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
cellular response to topologically incorrect protein GO:0035967 2 0.015
membrane invagination GO:0010324 1 0.015
negative regulation of myeloid cell differentiation GO:0045638 1 0.015
positive regulation of protein polymerization GO:0032273 2 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
transcription dna templated GO:0006351 181 0.015
membrane fusion GO:0061025 2 0.015
regulation of cell communication GO:0010646 232 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
proteolysis GO:0006508 38 0.015
nucleus organization GO:0006997 7 0.015
mononuclear cell proliferation GO:0032943 1 0.015
hormone transport GO:0009914 2 0.015
positive regulation of secretion GO:0051047 1 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
regulation of dna replication GO:0006275 3 0.014
signal transduction GO:0007165 455 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
heart development GO:0007507 313 0.014
smooth muscle contraction GO:0006939 2 0.014
lipid storage GO:0019915 1 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
establishment of localization in cell GO:0051649 77 0.014
exocytosis GO:0006887 1 0.014
protein localization to plasma membrane GO:0072659 1 0.014
cortical actin cytoskeleton organization GO:0030866 1 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
regulation of molecular function GO:0065009 70 0.014
response to carbohydrate GO:0009743 3 0.014
regulation of mrna processing GO:0050684 3 0.014
nephron epithelium morphogenesis GO:0072088 1 0.014
cellular protein metabolic process GO:0044267 129 0.014
somatic muscle development GO:0007525 4 0.014
response to ketone GO:1901654 1 0.014
cortical cytoskeleton organization GO:0030865 1 0.014
response to organic substance GO:0010033 153 0.014
response to hexose GO:0009746 3 0.014
regulation of hormone secretion GO:0046883 2 0.013
angiogenesis GO:0001525 158 0.013
regulation of localization GO:0032879 104 0.013
cellular component disassembly GO:0022411 1 0.013
secondary metabolic process GO:0019748 3 0.013
autophagy GO:0006914 4 0.013
macromolecular complex assembly GO:0065003 35 0.013
calcium ion import GO:0070509 4 0.013
regulation of microtubule cytoskeleton organization GO:0070507 3 0.013
hormone secretion GO:0046879 2 0.013
positive regulation of muscle cell differentiation GO:0051149 1 0.013
cellular biosynthetic process GO:0044249 286 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
hydrogen peroxide metabolic process GO:0042743 2 0.013
response to wounding GO:0009611 116 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
positive regulation of cell communication GO:0010647 56 0.013
multicellular organismal macromolecule metabolic process GO:0044259 2 0.013
negative regulation of cytokine production GO:0001818 1 0.013
actin filament based movement GO:0030048 1 0.013
cell substrate adhesion GO:0031589 4 0.013
striated muscle cell differentiation GO:0051146 129 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
lamellipodium organization GO:0097581 1 0.013
female gonad development GO:0008585 4 0.013
response to monosaccharide GO:0034284 3 0.013
protein homooligomerization GO:0051260 3 0.013
somitogenesis GO:0001756 87 0.013
cell morphogenesis GO:0000902 289 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.012
leukocyte mediated cytotoxicity GO:0001909 1 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
regulation of circadian rhythm GO:0042752 4 0.012
response to hydrogen peroxide GO:0042542 3 0.012
positive regulation of neuron apoptotic process GO:0043525 1 0.012
regulation of myotube differentiation GO:0010830 2 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
nucleic acid templated transcription GO:0097659 181 0.012
collagen metabolic process GO:0032963 2 0.012
olfactory lobe development GO:0021988 4 0.012
negative regulation of neural precursor cell proliferation GO:2000178 1 0.012
post embryonic morphogenesis GO:0009886 4 0.012
antimicrobial humoral response GO:0019730 2 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
developmental growth GO:0048589 166 0.012
regulation of cell matrix adhesion GO:0001952 1 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
apoptotic process GO:0006915 116 0.012
sensory system development GO:0048880 76 0.012
centrosome cycle GO:0007098 1 0.012
positive regulation of synapse assembly GO:0051965 1 0.012
peptide metabolic process GO:0006518 1 0.012
negative regulation of epithelial cell migration GO:0010633 1 0.012
oocyte maturation GO:0001556 4 0.012
death GO:0016265 121 0.012
actin mediated cell contraction GO:0070252 1 0.012
renal tubule morphogenesis GO:0061333 1 0.012
axonogenesis GO:0007409 152 0.012
cell cycle arrest GO:0007050 1 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
cell motility GO:0048870 244 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
negative regulation of gene expression GO:0010629 65 0.012
regulation of cellular response to growth factor stimulus GO:0090287 35 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
negative regulation of multi organism process GO:0043901 3 0.011
lateral inhibition GO:0046331 1 0.011
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
single organism membrane fusion GO:0044801 2 0.011
circulatory system process GO:0003013 87 0.011
positive regulation of cell division GO:0051781 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
complement activation GO:0006956 3 0.011
androgen biosynthetic process GO:0006702 1 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
regulation of cellular response to oxidative stress GO:1900407 2 0.011
endosomal transport GO:0016197 2 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
positive regulation of cell activation GO:0050867 1 0.011
negative regulation of protein kinase b signaling GO:0051898 2 0.011
positive regulation of jak stat cascade GO:0046427 2 0.011
protein complex biogenesis GO:0070271 30 0.011
regulation of apoptotic process GO:0042981 98 0.011
stem cell division GO:0017145 1 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
locomotor rhythm GO:0045475 3 0.011
actin filament polymerization GO:0030041 2 0.011
cellular response to hypoxia GO:0071456 1 0.011
entrainment of circadian clock GO:0009649 2 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
anterior posterior pattern specification GO:0009952 152 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.011
regulation of neuronal synaptic plasticity GO:0048168 1 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
embryonic organ development GO:0048568 381 0.011
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.011
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.011
muscle organ development GO:0007517 101 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
somite development GO:0061053 96 0.011
cellular response to unfolded protein GO:0034620 2 0.011
peptide transport GO:0015833 1 0.011
rna biosynthetic process GO:0032774 181 0.011
regulation of blood pressure GO:0008217 1 0.011
response to inorganic substance GO:0010035 38 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.011
leukocyte proliferation GO:0070661 1 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
immune response GO:0006955 28 0.011
protein complex localization GO:0031503 1 0.011
embryonic skeletal system development GO:0048706 97 0.011
negative regulation of immune response GO:0050777 2 0.011
regulation of immune system process GO:0002682 34 0.011
regulation of cellular component organization GO:0051128 86 0.011
somatic stem cell maintenance GO:0035019 1 0.010
long chain fatty acid transport GO:0015909 1 0.010
somatic cell dna recombination GO:0016444 1 0.010
stem cell differentiation GO:0048863 117 0.010
alcohol biosynthetic process GO:0046165 2 0.010
neuron development GO:0048666 262 0.010
negative regulation of synapse assembly GO:0051964 2 0.010
reactive oxygen species metabolic process GO:0072593 6 0.010
positive regulation of neuron death GO:1901216 1 0.010
response to glucose GO:0009749 3 0.010
negative regulation of kinase activity GO:0033673 4 0.010
b cell mediated immunity GO:0019724 3 0.010
nucleobase containing compound biosynthetic process GO:0034654 205 0.010
cytoplasm organization GO:0007028 4 0.010
myeloid cell differentiation GO:0030099 86 0.010
embryonic cranial skeleton morphogenesis GO:0048701 90 0.010
protein complex disassembly GO:0043241 1 0.010
negative regulation of metabolic process GO:0009892 86 0.010
protein complex assembly GO:0006461 30 0.010
pyruvate metabolic process GO:0006090 1 0.010
axon development GO:0061564 166 0.010

zgc:103580 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
nervous system disease DOID:863 0 0.035
myopathy DOID:423 0 0.021
muscular disease DOID:0080000 0 0.021
musculoskeletal system disease DOID:17 0 0.021
muscle tissue disease DOID:66 0 0.021
cardiovascular system disease DOID:1287 0 0.017
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
disease of metabolism DOID:0014667 0 0.012
connective tissue disease DOID:65 0 0.011