Danio rerio

0 known processes

zgc:56518

zgc:56518

zgc:56518 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
hydrogen peroxide metabolic process GO:0042743 2 0.265
cellular nitrogen compound biosynthetic process GO:0044271 218 0.176
larval development GO:0002164 2 0.169
regulation of multicellular organism growth GO:0040014 4 0.116
regulation of biological quality GO:0065008 263 0.103
cellular modified amino acid metabolic process GO:0006575 3 0.100
oxoacid metabolic process GO:0043436 31 0.091
cellular nitrogen compound metabolic process GO:0034641 290 0.086
maintenance of location GO:0051235 4 0.084
organic acid metabolic process GO:0006082 31 0.080
regulation of multicellular organismal process GO:0051239 277 0.079
multicellular organism growth GO:0035264 4 0.072
small molecule catabolic process GO:0044282 3 0.071
regulation of response to stimulus GO:0048583 269 0.070
aging GO:0007568 2 0.070
tube morphogenesis GO:0035239 349 0.061
small molecule metabolic process GO:0044281 77 0.061
single organism metabolic process GO:0044710 217 0.057
neuron differentiation GO:0030182 353 0.052
superoxide metabolic process GO:0006801 2 0.051
response to chemical GO:0042221 320 0.051
reactive oxygen species metabolic process GO:0072593 6 0.050
generation of neurons GO:0048699 385 0.050
cellular aromatic compound metabolic process GO:0006725 295 0.050
regulation of signaling GO:0023051 235 0.048
carboxylic acid metabolic process GO:0019752 22 0.048
carboxylic acid catabolic process GO:0046395 3 0.047
i kappab kinase nf kappab signaling GO:0007249 4 0.045
nitrogen compound metabolic process GO:0006807 319 0.043
heart development GO:0007507 313 0.043
specification of symmetry GO:0009799 204 0.043
heterocycle metabolic process GO:0046483 290 0.043
cellular response to reactive oxygen species GO:0034614 2 0.043
response to stress GO:0006950 263 0.043
response to hydrogen peroxide GO:0042542 3 0.042
cellular macromolecule metabolic process GO:0044260 391 0.042
cellular aldehyde metabolic process GO:0006081 4 0.042
nucleic acid metabolic process GO:0090304 244 0.042
nucleic acid templated transcription GO:0097659 181 0.041
phagocytosis GO:0006909 3 0.041
morphogenesis of an epithelium GO:0002009 333 0.041
transcription dna templated GO:0006351 181 0.040
regulation of reactive oxygen species metabolic process GO:2000377 2 0.040
organonitrogen compound metabolic process GO:1901564 74 0.039
regulation of cytokine production GO:0001817 3 0.039
blood vessel development GO:0001568 246 0.038
cellular response to lipopolysaccharide GO:0071222 3 0.037
regulation of metabolic process GO:0019222 359 0.036
response to external stimulus GO:0009605 264 0.035
regulation of blood pressure GO:0008217 1 0.035
hematopoietic or lymphoid organ development GO:0048534 191 0.035
positive regulation of transport GO:0051050 2 0.035
growth GO:0040007 174 0.035
regulation of signal transduction GO:0009966 225 0.035
negative regulation of cellular process GO:0048523 283 0.034
negative regulation of biological process GO:0048519 304 0.034
dicarboxylic acid metabolic process GO:0043648 1 0.034
cellular response to chemical stimulus GO:0070887 157 0.034
sensory organ development GO:0007423 393 0.033
determination of left right symmetry GO:0007368 179 0.033
nucleobase containing compound metabolic process GO:0006139 274 0.033
regulation of peptidase activity GO:0052547 23 0.032
rna biosynthetic process GO:0032774 181 0.032
adult behavior GO:0030534 2 0.032
organic cyclic compound metabolic process GO:1901360 301 0.032
signal transduction GO:0007165 455 0.032
gene expression GO:0010467 252 0.032
oxidation reduction process GO:0055114 41 0.031
immune system process GO:0002376 241 0.031
determination of bilateral symmetry GO:0009855 204 0.031
alcohol biosynthetic process GO:0046165 2 0.030
cellular component morphogenesis GO:0032989 336 0.030
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.030
stem cell proliferation GO:0072089 4 0.030
cellular response to biotic stimulus GO:0071216 3 0.030
lipid storage GO:0019915 1 0.030
response to inorganic substance GO:0010035 38 0.029
neuron development GO:0048666 262 0.029
neuroblast proliferation GO:0007405 2 0.029
phagocytosis engulfment GO:0006911 1 0.029
cellular amino acid metabolic process GO:0006520 7 0.028
regulation of primary metabolic process GO:0080090 311 0.028
heterocycle biosynthetic process GO:0018130 215 0.028
gland development GO:0048732 143 0.028
regulation of cell communication GO:0010646 232 0.027
cell morphogenesis GO:0000902 289 0.027
angiogenesis GO:0001525 158 0.027
cellular response to superoxide GO:0071451 2 0.027
monocarboxylic acid catabolic process GO:0072329 3 0.027
response to wounding GO:0009611 116 0.027
regulation of gene expression GO:0010468 265 0.027
regulation of nitrogen compound metabolic process GO:0051171 251 0.027
regulation of transcription dna templated GO:0006355 213 0.026
organic cyclic compound biosynthetic process GO:1901362 223 0.026
regulation of response to biotic stimulus GO:0002831 2 0.026
aromatic compound biosynthetic process GO:0019438 217 0.026
mononuclear cell proliferation GO:0032943 1 0.026
ion transport GO:0006811 114 0.026
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.026
positive regulation of biological process GO:0048518 253 0.025
peptide metabolic process GO:0006518 1 0.025
regulation of tube size GO:0035150 2 0.025
regulation of ion transmembrane transporter activity GO:0032412 2 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.024
regulation of macromolecule biosynthetic process GO:0010556 225 0.024
regulation of wound healing GO:0061041 2 0.024
regulation of rna metabolic process GO:0051252 224 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
neurotransmitter transport GO:0006836 2 0.024
response to lipid GO:0033993 60 0.023
nucleoside monophosphate catabolic process GO:0009125 4 0.023
regulation of transmembrane transporter activity GO:0022898 2 0.023
cell part morphogenesis GO:0032990 246 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.022
pyruvate metabolic process GO:0006090 1 0.022
negative regulation of kinase activity GO:0033673 4 0.022
digestive system development GO:0055123 289 0.022
apoptotic process GO:0006915 116 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
cellular macromolecule biosynthetic process GO:0034645 224 0.022
extrinsic apoptotic signaling pathway GO:0097191 3 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.021
regulation of cell activation GO:0050865 1 0.021
transmembrane transport GO:0055085 120 0.021
leukocyte proliferation GO:0070661 1 0.021
embryo development ending in birth or egg hatching GO:0009792 271 0.021
negative regulation of multicellular organismal process GO:0051241 69 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.021
alpha amino acid metabolic process GO:1901605 3 0.021
regulation of binding GO:0051098 3 0.021
response to vitamin GO:0033273 3 0.021
branched chain amino acid metabolic process GO:0009081 1 0.021
positive regulation of cytokine production GO:0001819 2 0.020
protein metabolic process GO:0019538 183 0.020
zymogen activation GO:0031638 3 0.020
developmental growth GO:0048589 166 0.020
amine metabolic process GO:0009308 2 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
internal protein amino acid acetylation GO:0006475 2 0.019
cellular amide metabolic process GO:0043603 4 0.019
heart morphogenesis GO:0003007 156 0.019
cell projection organization GO:0030030 284 0.019
negative regulation of signaling GO:0023057 96 0.019
cellular amino acid biosynthetic process GO:0008652 2 0.019
regulation of cysteine type endopeptidase activity GO:2000116 21 0.019
rna metabolic process GO:0016070 219 0.019
xenobiotic metabolic process GO:0006805 4 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
camera type eye development GO:0043010 222 0.019
response to oxygen radical GO:0000305 2 0.019
wound healing GO:0042060 90 0.019
membrane invagination GO:0010324 1 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.019
cell death GO:0008219 121 0.018
regulation of rna biosynthetic process GO:2001141 213 0.018
embryonic organ development GO:0048568 381 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
negative regulation of leukocyte differentiation GO:1902106 1 0.018
response to uv GO:0009411 3 0.018
energy reserve metabolic process GO:0006112 2 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
digestive tract development GO:0048565 265 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.018
negative regulation of reproductive process GO:2000242 3 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
epithelial tube morphogenesis GO:0060562 148 0.018
urogenital system development GO:0001655 97 0.018
cell projection morphogenesis GO:0048858 244 0.017
response to endogenous stimulus GO:0009719 83 0.017
macromolecule biosynthetic process GO:0009059 227 0.017
regulation of cell differentiation GO:0045595 142 0.017
regulation of biosynthetic process GO:0009889 250 0.017
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.017
protein localization to nucleus GO:0034504 3 0.017
mitochondrial transport GO:0006839 2 0.017
response to organic substance GO:0010033 153 0.017
negative regulation of cell communication GO:0010648 96 0.017
negative regulation of response to stimulus GO:0048585 104 0.017
regulation of blood vessel size GO:0050880 2 0.017
negative regulation of signal transduction GO:0009968 94 0.017
intracellular estrogen receptor signaling pathway GO:0030520 3 0.017
programmed cell death GO:0012501 119 0.017
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.017
cellular protein metabolic process GO:0044267 129 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
establishment of localization GO:0051234 244 0.017
response to nutrient GO:0007584 3 0.017
ion transmembrane transport GO:0034220 91 0.016
anion transmembrane transport GO:0098656 12 0.016
gastrulation GO:0007369 208 0.016
regulation of transporter activity GO:0032409 2 0.016
sensory organ morphogenesis GO:0090596 200 0.016
protein acetylation GO:0006473 2 0.016
positive regulation of map kinase activity GO:0043406 3 0.016
lipid homeostasis GO:0055088 3 0.016
cellular response to stress GO:0033554 62 0.016
negative regulation of biosynthetic process GO:0009890 55 0.016
negative regulation of cytokine production GO:0001818 1 0.015
embryonic heart tube development GO:0035050 133 0.015
regulation of developmental process GO:0050793 247 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
cellular response to oxygen radical GO:0071450 2 0.015
regulation of endopeptidase activity GO:0052548 23 0.015
intracellular signal transduction GO:0035556 85 0.015
organic substance biosynthetic process GO:1901576 289 0.015
cellular amine metabolic process GO:0044106 2 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
embryonic heart tube morphogenesis GO:0003143 108 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
anion transport GO:0006820 38 0.015
homeostatic process GO:0042592 142 0.015
protein acylation GO:0043543 3 0.015
glial cell migration GO:0008347 3 0.015
lymphocyte proliferation GO:0046651 1 0.015
organic acid catabolic process GO:0016054 3 0.015
response to oxidative stress GO:0006979 11 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
cellular protein modification process GO:0006464 100 0.014
regulation of metal ion transport GO:0010959 4 0.014
response to other organism GO:0051707 97 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
blood vessel morphogenesis GO:0048514 216 0.014
regulation of circadian rhythm GO:0042752 4 0.014
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.014
cellular lipid catabolic process GO:0044242 3 0.014
regulation of cellular response to oxidative stress GO:1900407 2 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
response to drug GO:0042493 3 0.014
response to superoxide GO:0000303 2 0.014
regulation of reproductive process GO:2000241 4 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
multicellular organismal macromolecule metabolic process GO:0044259 2 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
multicellular organismal metabolic process GO:0044236 2 0.013
biosynthetic process GO:0009058 294 0.013
regulation of blood coagulation GO:0030193 1 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
cellular component biogenesis GO:0044085 178 0.013
regulation of inflammatory response GO:0050727 2 0.013
response to metal ion GO:0010038 34 0.013
regulation of cell shape GO:0008360 1 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
regulation of filopodium assembly GO:0051489 2 0.013
single organism transport GO:0044765 206 0.013
female gonad development GO:0008585 4 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
positive regulation of cellular process GO:0048522 201 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
cellular component assembly GO:0022607 170 0.013
hemopoiesis GO:0030097 183 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
hepaticobiliary system development GO:0061008 98 0.013
system process GO:0003008 185 0.013
cellular ketone metabolic process GO:0042180 11 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
multi organism process GO:0051704 134 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
single organism localization GO:1902578 225 0.012
skeletal system development GO:0001501 181 0.012
response to vitamin b3 GO:0033552 2 0.012
regulation of cell projection assembly GO:0060491 4 0.012
negative regulation of metabolic process GO:0009892 86 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
cellular response to lipid GO:0071396 39 0.012
cell death in response to oxidative stress GO:0036473 2 0.012
monoamine transport GO:0015844 1 0.012
retinoic acid receptor signaling pathway GO:0048384 16 0.012
regulation of apoptotic process GO:0042981 98 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
response to reactive oxygen species GO:0000302 5 0.012
regulation of ion transport GO:0043269 22 0.012
chemotaxis GO:0006935 104 0.012
response to bacterium GO:0009617 58 0.011
death GO:0016265 121 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
positive regulation of muscle cell differentiation GO:0051149 1 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
heart looping GO:0001947 94 0.011
regulation of hemostasis GO:1900046 1 0.011
eye development GO:0001654 277 0.011
response to external biotic stimulus GO:0043207 97 0.011
central nervous system development GO:0007417 387 0.011
brain development GO:0007420 293 0.011
removal of superoxide radicals GO:0019430 2 0.011
mitochondrion organization GO:0007005 4 0.011
positive regulation of immune effector process GO:0002699 3 0.011
regulation of striated muscle contraction GO:0006942 2 0.011
inner ear development GO:0048839 126 0.011
positive regulation of secretion GO:0051047 1 0.011
spermatid development GO:0007286 2 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
negative regulation of multi organism process GO:0043901 3 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
multicellular organismal response to stress GO:0033555 2 0.011
neuron projection morphogenesis GO:0048812 161 0.011
negative regulation of gene expression GO:0010629 65 0.011
negative regulation of protein transport GO:0051224 3 0.011
regulation of calcium ion transport GO:0051924 2 0.011
nuclear import GO:0051170 3 0.011
phosphorus metabolic process GO:0006793 109 0.010
reactive oxygen species biosynthetic process GO:1903409 1 0.010
establishment of protein localization to organelle GO:0072594 4 0.010
blood circulation GO:0008015 87 0.010
negative regulation of catabolic process GO:0009895 3 0.010
secondary metabolic process GO:0019748 3 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
regulation of protein binding GO:0043393 3 0.010
cellular response to organic substance GO:0071310 105 0.010
positive regulation of cell activation GO:0050867 1 0.010
positive regulation of jnk cascade GO:0046330 3 0.010
regulation of neuronal synaptic plasticity GO:0048168 1 0.010
regulation of intracellular signal transduction GO:1902531 57 0.010
vasculature development GO:0001944 278 0.010
regulation of protein catabolic process GO:0042176 1 0.010
cation transport GO:0006812 81 0.010
negative regulation of endopeptidase activity GO:0010951 10 0.010

zgc:56518 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
disease of metabolism DOID:0014667 0 0.034
inherited metabolic disorder DOID:655 0 0.034
nervous system disease DOID:863 0 0.020
amino acid metabolic disorder DOID:9252 0 0.017
musculoskeletal system disease DOID:17 0 0.011
mitochondrial metabolism disease DOID:700 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
cancer DOID:162 0 0.010