Danio rerio

38 known processes

zic1

zic family member 1 (odd-paired homolog, Drosophila)

(Aliases: MGC136736,opl,zgc:136736,wu:fj51c06,MGC76803)

zic1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell proliferation in forebrain GO:0021846 3 0.990
Zebrafish
determination of left right symmetry GO:0007368 179 0.962
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.954
Mouse Fly
cell proliferation in hindbrain GO:0021534 4 0.948
forebrain anterior posterior pattern specification GO:0021797 3 0.906
larval development GO:0002164 2 0.891
Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.889
Zebrafish Mouse Fly
regulation of inner ear receptor cell differentiation GO:2000980 1 0.881
nucleobase containing compound biosynthetic process GO:0034654 205 0.879
Zebrafish Mouse Worm Fly
hindbrain development GO:0030902 91 0.875
regulation of biosynthetic process GO:0009889 250 0.865
Zebrafish Mouse Fly
regulation of cell differentiation GO:0045595 142 0.859
retina morphogenesis in camera type eye GO:0060042 79 0.859
embryonic organ morphogenesis GO:0048562 274 0.851
Zebrafish
regulation of gene expression GO:0010468 265 0.846
Zebrafish Mouse Fly
forebrain morphogenesis GO:0048853 6 0.833
heterocycle biosynthetic process GO:0018130 215 0.816
Zebrafish Mouse Worm Fly
regulation of smoothened signaling pathway GO:0008589 18 0.809
Zebrafish Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.804
Zebrafish Mouse Fly
forebrain neuron fate commitment GO:0021877 1 0.796
ventricular system development GO:0021591 12 0.779
sensory organ development GO:0007423 393 0.775
digestive system development GO:0055123 289 0.761
Fly
cell migration GO:0016477 237 0.759
Fly
neuron fate commitment GO:0048663 26 0.741
Worm
neuron projection morphogenesis GO:0048812 161 0.734
nucleic acid metabolic process GO:0090304 244 0.727
Zebrafish Mouse Worm Fly
neuron differentiation GO:0030182 353 0.721
Worm
positive regulation of rna biosynthetic process GO:1902680 57 0.709
Mouse Fly
negative regulation of cellular process GO:0048523 283 0.699
Zebrafish
specification of symmetry GO:0009799 204 0.696
Zebrafish
positive regulation of cellular process GO:0048522 201 0.693
Mouse Fly
cell proliferation in midbrain GO:0033278 4 0.691
Zebrafish
forebrain neuron development GO:0021884 7 0.669
heart morphogenesis GO:0003007 156 0.667
tube morphogenesis GO:0035239 349 0.666
Zebrafish
diencephalon development GO:0021536 58 0.659
Zebrafish
abducens nucleus development GO:0021742 2 0.655
camera type eye morphogenesis GO:0048593 108 0.652
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.645
Zebrafish Mouse Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.625
Zebrafish Mouse Worm Fly
regulation of cellular metabolic process GO:0031323 320 0.621
Zebrafish Mouse Fly
determination of bilateral symmetry GO:0009855 204 0.615
Zebrafish
neural precursor cell proliferation GO:0061351 20 0.607
cellular macromolecule metabolic process GO:0044260 391 0.603
Zebrafish Mouse Worm Fly
neuroblast proliferation GO:0007405 2 0.602
central nervous system development GO:0007417 387 0.599
forebrain regionalization GO:0021871 4 0.599
embryonic viscerocranium morphogenesis GO:0048703 52 0.593
Zebrafish
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.586
positive regulation of rna metabolic process GO:0051254 59 0.576
Mouse Fly
negative regulation of transcription dna templated GO:0045892 45 0.557
Zebrafish
developmental growth GO:0048589 166 0.556
stem cell development GO:0048864 82 0.527
Zebrafish
embryonic heart tube development GO:0035050 133 0.523
axis specification GO:0009798 43 0.516
Zebrafish
neuron projection development GO:0031175 180 0.515
embryonic heart tube morphogenesis GO:0003143 108 0.511
cell fate commitment GO:0045165 99 0.502
Worm
organic cyclic compound biosynthetic process GO:1901362 223 0.491
Zebrafish Mouse Worm Fly
regulation of signaling GO:0023051 235 0.489
Zebrafish Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.461
Zebrafish Mouse Worm Fly
neuron fate specification GO:0048665 20 0.460
Worm
stem cell proliferation GO:0072089 4 0.449
signal transduction GO:0007165 455 0.448
Zebrafish Mouse Fly
negative regulation of gene expression GO:0010629 65 0.447
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.442
Zebrafish Mouse Worm Fly
transcription dna templated GO:0006351 181 0.436
Zebrafish Mouse Worm Fly
epithelial cell differentiation GO:0030855 116 0.422
heart development GO:0007507 313 0.418
smoothened signaling pathway GO:0007224 30 0.414
Zebrafish Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.410
Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.409
Mouse Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.408
Zebrafish Mouse Worm Fly
heart looping GO:0001947 94 0.406
embryonic camera type eye development GO:0031076 29 0.403
regulation of macromolecule biosynthetic process GO:0010556 225 0.396
Zebrafish Mouse Fly
fourth ventricle development GO:0021592 8 0.395
biosynthetic process GO:0009058 294 0.393
Zebrafish Mouse Worm Fly
heterocycle metabolic process GO:0046483 290 0.391
Zebrafish Mouse Worm Fly
nucleobase containing compound metabolic process GO:0006139 274 0.383
Zebrafish Mouse Worm Fly
negative regulation of nucleic acid templated transcription GO:1903507 45 0.380
Zebrafish
dorsal ventral pattern formation GO:0009953 125 0.377
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.376
Zebrafish Mouse Worm Fly
connective tissue development GO:0061448 99 0.373
regionalization GO:0003002 274 0.366
Zebrafish
generation of neurons GO:0048699 385 0.363
Worm
macromolecule biosynthetic process GO:0009059 227 0.361
Zebrafish Mouse Worm Fly
response to stress GO:0006950 263 0.360
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.357
Fly
cell fate specification GO:0001708 68 0.351
Worm
determination of heart left right asymmetry GO:0061371 117 0.349
cell projection morphogenesis GO:0048858 244 0.346
forebrain development GO:0030900 96 0.341
death GO:0016265 121 0.334
morphogenesis of an epithelium GO:0002009 333 0.333
Zebrafish
morphogenesis of embryonic epithelium GO:0016331 30 0.330
Zebrafish
rna biosynthetic process GO:0032774 181 0.329
Zebrafish Mouse Worm Fly
olfactory lobe development GO:0021988 4 0.329
regulation of rna metabolic process GO:0051252 224 0.328
Zebrafish Mouse Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.317
localization of cell GO:0051674 244 0.315
Fly
regulation of cell communication GO:0010646 232 0.315
Zebrafish Mouse
skeletal system morphogenesis GO:0048705 102 0.315
Zebrafish
positive regulation of biosynthetic process GO:0009891 68 0.311
Mouse Fly
regeneration GO:0031099 91 0.304
regulation of developmental process GO:0050793 247 0.301
mechanoreceptor differentiation GO:0042490 37 0.294
cell surface receptor signaling pathway GO:0007166 325 0.291
Zebrafish Mouse Fly
mesenchymal cell development GO:0014031 78 0.290
Zebrafish
epithelial tube formation GO:0072175 19 0.289
Zebrafish
primary neural tube formation GO:0014020 1 0.283
embryonic organ development GO:0048568 381 0.279
Zebrafish
enzyme linked receptor protein signaling pathway GO:0007167 106 0.276
Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.274
Mouse Fly
forebrain neuron differentiation GO:0021879 14 0.274
taxis GO:0042330 109 0.274
central nervous system neuron differentiation GO:0021953 74 0.269
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.268
Fly
cell projection organization GO:0030030 284 0.268
positive regulation of macromolecule metabolic process GO:0010604 93 0.267
Mouse Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.265
eye morphogenesis GO:0048592 144 0.262
midbrain development GO:0030901 28 0.262
Zebrafish
neural tube development GO:0021915 62 0.261
Zebrafish
ventral spinal cord interneuron fate commitment GO:0060579 3 0.259
regulation of response to stimulus GO:0048583 269 0.256
Zebrafish Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.253
Zebrafish Mouse Fly
neuron fate determination GO:0048664 2 0.251
camera type eye development GO:0043010 222 0.251
embryonic skeletal system morphogenesis GO:0048704 93 0.246
Zebrafish
embryonic cranial skeleton morphogenesis GO:0048701 90 0.245
Zebrafish
positive regulation of transcription dna templated GO:0045893 57 0.239
Mouse Fly
positive regulation of metabolic process GO:0009893 108 0.239
Mouse Fly
digestive tract development GO:0048565 265 0.232
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.229
Zebrafish Mouse Fly
regulation of stem cell proliferation GO:0072091 2 0.228
dna templated transcription initiation GO:0006352 1 0.227
Worm
positive regulation of multicellular organismal process GO:0051240 52 0.225
brain development GO:0007420 293 0.219
sensory organ morphogenesis GO:0090596 200 0.217
mesodermal cell fate commitment GO:0001710 14 0.216
embryonic skeletal system development GO:0048706 97 0.214
Zebrafish
diencephalon morphogenesis GO:0048852 5 0.209
adenohypophysis development GO:0021984 15 0.207
eye development GO:0001654 277 0.207
negative regulation of macromolecule metabolic process GO:0010605 76 0.205
Zebrafish
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.204
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.203
growth GO:0040007 174 0.201
maintenance of location GO:0051235 4 0.197
Worm
axon guidance GO:0007411 86 0.196
forebrain generation of neurons GO:0021872 14 0.193
cranial nerve development GO:0021545 42 0.183
central nervous system neuron development GO:0021954 29 0.183
chemotaxis GO:0006935 104 0.183
cell motility GO:0048870 244 0.182
Fly
neuromast development GO:0048884 46 0.182
multicellular organism growth GO:0035264 4 0.180
regulation of primary metabolic process GO:0080090 311 0.178
Zebrafish Mouse Fly
rostrocaudal neural tube patterning GO:0021903 29 0.175
positive regulation of cellular metabolic process GO:0031325 94 0.169
Mouse Fly
system process GO:0003008 185 0.166
appendage development GO:0048736 80 0.163
neuroblast differentiation GO:0014016 1 0.162
reproductive process GO:0022414 40 0.159
Worm Fly
cell part morphogenesis GO:0032990 246 0.158
locomotion GO:0040011 313 0.154
Worm Fly
neural tube patterning GO:0021532 33 0.153
behavior GO:0007610 74 0.151
Mouse Worm
aromatic compound biosynthetic process GO:0019438 217 0.150
Zebrafish Mouse Worm Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.150
Zebrafish
mesenchymal cell differentiation GO:0048762 87 0.149
Zebrafish
cell cell signaling GO:0007267 52 0.149
positive regulation of nervous system development GO:0051962 25 0.149
regulation of metabolic process GO:0019222 359 0.144
Zebrafish Mouse Fly
oligodendrocyte cell fate specification GO:0021778 4 0.144
regulation of macromolecule metabolic process GO:0060255 317 0.143
Zebrafish Mouse Fly
immune system process GO:0002376 241 0.142
limbic system development GO:0021761 16 0.142
mesenchyme development GO:0060485 127 0.135
Zebrafish
regulation of nervous system development GO:0051960 90 0.134
negative regulation of neurogenesis GO:0050768 20 0.133
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.133
Mouse Fly
protein modification process GO:0036211 100 0.132
organic substance biosynthetic process GO:1901576 289 0.130
Zebrafish Mouse Worm Fly
pancreas development GO:0031016 84 0.128
cellular biosynthetic process GO:0044249 286 0.128
Zebrafish Mouse Worm Fly
response to organic substance GO:0010033 153 0.127
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.127
regulation of neurogenesis GO:0050767 87 0.126
embryonic camera type eye morphogenesis GO:0048596 19 0.125
organelle organization GO:0006996 227 0.125
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.124
Fly
positive regulation of stem cell proliferation GO:2000648 1 0.124
forebrain dorsal ventral pattern formation GO:0021798 1 0.123
protein metabolic process GO:0019538 183 0.123
cellular component morphogenesis GO:0032989 336 0.122
brain morphogenesis GO:0048854 18 0.122
palate development GO:0060021 8 0.121
cardiocyte differentiation GO:0035051 44 0.121
positive regulation of developmental process GO:0051094 50 0.121
negative regulation of cell development GO:0010721 26 0.119
head development GO:0060322 303 0.118
skeletal system development GO:0001501 181 0.118
Zebrafish
chordate embryonic development GO:0043009 271 0.117
Zebrafish
negative regulation of cellular metabolic process GO:0031324 77 0.116
Zebrafish
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.115
Zebrafish
regulation of mechanoreceptor differentiation GO:0045631 1 0.114
rna metabolic process GO:0016070 219 0.113
Zebrafish Mouse Worm Fly
neuron projection guidance GO:0097485 86 0.111
mammillary body development GO:0021767 4 0.110
regulation of endodermal cell fate specification GO:0042663 15 0.109
negative regulation of rna metabolic process GO:0051253 48 0.107
Zebrafish
mesoderm development GO:0007498 88 0.107
primitive hemopoiesis GO:0060215 27 0.107
ectodermal placode morphogenesis GO:0071697 32 0.105
muscle structure development GO:0061061 196 0.105
pituitary gland development GO:0021983 16 0.105
endodermal cell fate determination GO:0007493 2 0.104
multicellular organism reproduction GO:0032504 35 0.104
Worm Fly
gabaergic neuron differentiation GO:0097154 2 0.103
gland development GO:0048732 143 0.102
phosphate containing compound metabolic process GO:0006796 108 0.101
axon development GO:0061564 166 0.100
fin development GO:0033333 77 0.100
neuron development GO:0048666 262 0.099
compound eye development GO:0048749 2 0.099
endoderm development GO:0007492 49 0.099
auditory receptor cell fate commitment GO:0009912 4 0.099
gastrulation GO:0007369 208 0.098
olfactory bulb development GO:0021772 4 0.098
embryonic pectoral fin morphogenesis GO:0035118 24 0.097
striated muscle tissue development GO:0014706 110 0.097
regulation of multicellular organismal development GO:2000026 223 0.097
kidney development GO:0001822 92 0.095
inner ear receptor cell fate commitment GO:0060120 4 0.093
ear morphogenesis GO:0042471 64 0.093
negative regulation of biological process GO:0048519 304 0.092
Zebrafish
cranial nerve morphogenesis GO:0021602 15 0.092
neural nucleus development GO:0048857 15 0.091
negative regulation of cellular component organization GO:0051129 16 0.091
forebrain midbrain boundary formation GO:0021905 1 0.091
regulation of apoptotic process GO:0042981 98 0.088
negative regulation of neuron differentiation GO:0045665 10 0.087
pectoral fin morphogenesis GO:0035138 29 0.087
homeostatic process GO:0042592 142 0.087
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.087
Zebrafish
regulation of neural precursor cell proliferation GO:2000177 3 0.087
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.087
mitotic cell cycle GO:0000278 64 0.087
epithelial tube morphogenesis GO:0060562 148 0.086
Zebrafish
negative regulation of nervous system development GO:0051961 22 0.086
skin development GO:0043588 54 0.085
endocrine system development GO:0035270 65 0.085
pancreatic a cell development GO:0003322 2 0.084
vasculogenesis GO:0001570 41 0.084
negative regulation of biosynthetic process GO:0009890 55 0.083
Zebrafish
tissue regeneration GO:0042246 74 0.083
spinal cord development GO:0021510 46 0.082
Zebrafish Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.081
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.081
cellular response to organic substance GO:0071310 105 0.080
mesodermal cell fate specification GO:0007501 12 0.079
facial nucleus development GO:0021754 7 0.078
programmed cell death GO:0012501 119 0.078
regulation of transcription involved in cell fate commitment GO:0060850 1 0.077
positive regulation of cell cycle GO:0045787 3 0.077
epithelial cell development GO:0002064 42 0.075
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.075
Fly
apoptotic process GO:0006915 116 0.075
hematopoietic or lymphoid organ development GO:0048534 191 0.074
blood vessel morphogenesis GO:0048514 216 0.074
dopaminergic neuron differentiation GO:0071542 14 0.074
regulation of transcription dna templated GO:0006355 213 0.073
Zebrafish Mouse Fly
gastrulation with mouth forming second GO:0001702 44 0.073
negative regulation of cell differentiation GO:0045596 46 0.073
negative regulation of cellular biosynthetic process GO:0031327 55 0.073
Zebrafish
neuron migration GO:0001764 22 0.073
phosphorus metabolic process GO:0006793 109 0.072
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.071
Zebrafish
renal system development GO:0072001 94 0.071
pharyngeal muscle development GO:0043282 4 0.071
retinal cell programmed cell death GO:0046666 2 0.071
cellular component movement GO:0006928 335 0.070
Fly
cellular protein metabolic process GO:0044267 129 0.069
sex differentiation GO:0007548 5 0.068
Worm
negative regulation of cell death GO:0060548 60 0.068
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.068
Mouse Fly
midbrain hindbrain boundary development GO:0030917 23 0.067
lens morphogenesis in camera type eye GO:0002089 7 0.066
neural tube formation GO:0001841 16 0.066
Zebrafish
immune system development GO:0002520 191 0.066
positive regulation of biological process GO:0048518 253 0.066
Mouse Fly
angiogenesis GO:0001525 158 0.065
retina development in camera type eye GO:0060041 146 0.064
cell projection assembly GO:0030031 64 0.063
axon extension GO:0048675 45 0.062
regulation of cell proliferation GO:0042127 37 0.061
Zebrafish
positive regulation of neural precursor cell proliferation GO:2000179 1 0.061
telencephalon development GO:0021537 14 0.061
cellular response to chemical stimulus GO:0070887 157 0.061
peripheral nervous system neuron differentiation GO:0048934 28 0.060
regulation of growth GO:0040008 42 0.060
positive regulation of cell differentiation GO:0045597 30 0.060
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.060
negative regulation of metabolic process GO:0009892 86 0.059
Zebrafish
mesodermal cell differentiation GO:0048333 21 0.059
axonogenesis GO:0007409 152 0.058
pons development GO:0021548 11 0.057
nerve development GO:0021675 45 0.056
urogenital system development GO:0001655 97 0.056
anterior commissure morphogenesis GO:0021960 3 0.056
proximal distal pattern formation GO:0009954 1 0.056
cell proliferation GO:0008283 80 0.055
negative regulation of gliogenesis GO:0014014 1 0.055
negative regulation of rna biosynthetic process GO:1902679 45 0.055
Zebrafish
cardiac muscle cell differentiation GO:0055007 30 0.053
ectodermal placode formation GO:0060788 26 0.053
regulation of phosphorus metabolic process GO:0051174 43 0.052
regulation of oligodendrocyte differentiation GO:0048713 1 0.052
regulation of multicellular organism growth GO:0040014 4 0.052
hemopoiesis GO:0030097 183 0.052
metencephalon development GO:0022037 27 0.052
protein complex biogenesis GO:0070271 30 0.051
regulation of cell migration GO:0030334 40 0.050
negative regulation of wnt signaling pathway GO:0030178 30 0.049
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.049
negative regulation of multicellular organismal process GO:0051241 69 0.049
regulation of cell development GO:0060284 100 0.048
regulation of programmed cell death GO:0043067 101 0.048
regulation of rna biosynthetic process GO:2001141 213 0.047
Zebrafish Mouse Fly
hair cell differentiation GO:0035315 32 0.047
positive regulation of molecular function GO:0044093 33 0.047
determination of pancreatic left right asymmetry GO:0035469 11 0.046
appendage morphogenesis GO:0035107 56 0.045
negative regulation of signal transduction GO:0009968 94 0.045
cell morphogenesis GO:0000902 289 0.044
gene expression GO:0010467 252 0.044
Zebrafish Mouse Worm Fly
central nervous system neuron axonogenesis GO:0021955 18 0.044
neuroblast fate commitment GO:0014017 1 0.044
cartilage development GO:0051216 96 0.043
peripheral nervous system development GO:0007422 55 0.043
hepaticobiliary system development GO:0061008 98 0.043
anterior posterior axis specification GO:0009948 20 0.043
Zebrafish
regulation of catalytic activity GO:0050790 55 0.041
digestive tract morphogenesis GO:0048546 231 0.041
single organism localization GO:1902578 225 0.041
Mouse
sympathetic nervous system development GO:0048485 3 0.041
inner ear development GO:0048839 126 0.040
cardioblast migration GO:0003260 7 0.040
tube closure GO:0060606 1 0.040
nephron morphogenesis GO:0072028 2 0.040
regulation of cell death GO:0010941 103 0.040
central nervous system projection neuron axonogenesis GO:0021952 15 0.039
tube formation GO:0035148 25 0.039
Zebrafish
germ cell migration GO:0008354 8 0.039
Fly
regulation of bmp signaling pathway GO:0030510 39 0.039
eye photoreceptor cell development GO:0042462 30 0.039
regulation of locomotion GO:0040012 55 0.039
establishment of mitotic spindle orientation GO:0000132 10 0.038
positive regulation of gene expression GO:0010628 71 0.038
Mouse Fly
regulation of binding GO:0051098 3 0.037
negative regulation of programmed cell death GO:0043069 58 0.037
embryonic epithelial tube formation GO:0001838 17 0.037
Zebrafish
retinal pigment epithelium development GO:0003406 8 0.037
positive regulation of cell communication GO:0010647 56 0.037
macromolecule modification GO:0043412 111 0.036
cellular aromatic compound metabolic process GO:0006725 295 0.036
Zebrafish Mouse Worm Fly
inner ear morphogenesis GO:0042472 63 0.036
glial cell migration GO:0008347 3 0.036
vasculature development GO:0001944 278 0.036
heart jogging GO:0003146 40 0.036
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.036
single organism organelle organization GO:1902589 199 0.036
epithelium regeneration GO:1990399 14 0.035
gliogenesis GO:0042063 45 0.035
astrocyte differentiation GO:0048708 1 0.035
cellular protein modification process GO:0006464 100 0.035
lipid storage GO:0019915 1 0.035
Worm
negative regulation of apoptotic process GO:0043066 55 0.035
spinal cord motor neuron differentiation GO:0021522 26 0.035
wound healing GO:0042060 90 0.035
autonomic nervous system development GO:0048483 19 0.034
definitive hemopoiesis GO:0060216 18 0.034
ventral spinal cord development GO:0021517 35 0.034
formation of primary germ layer GO:0001704 62 0.033
convergent extension involved in organogenesis GO:0060029 10 0.033
olfactory placode development GO:0071698 12 0.033
embryonic hemopoiesis GO:0035162 53 0.033
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.032
canonical wnt signaling pathway GO:0060070 48 0.032
Zebrafish
cell migration to the midline involved in heart development GO:0003318 12 0.032
regulation of biological quality GO:0065008 263 0.032
Worm
nitrogen compound metabolic process GO:0006807 319 0.032
Zebrafish Mouse Worm Fly
liver development GO:0001889 96 0.032
neuron projection regeneration GO:0031102 16 0.031
brain segmentation GO:0035284 6 0.031
fin morphogenesis GO:0033334 53 0.031
glandular epithelial cell differentiation GO:0002067 9 0.031
blood vessel development GO:0001568 246 0.031
negative regulation of axon guidance GO:1902668 1 0.031
positive regulation of signaling GO:0023056 56 0.031
kupffer s vesicle development GO:0070121 50 0.030
regulation of cell cycle GO:0051726 52 0.030
endothelial cell differentiation GO:0045446 20 0.030
erythrocyte homeostasis GO:0034101 55 0.030
muscle cell differentiation GO:0042692 139 0.029
gamete generation GO:0007276 33 0.029
Fly
iris morphogenesis GO:0061072 1 0.028
regulation of epithelial cell proliferation GO:0050678 3 0.028
regulation of protein metabolic process GO:0051246 56 0.028
hematopoietic progenitor cell differentiation GO:0002244 23 0.028
renal tubule morphogenesis GO:0061333 1 0.027
stem cell fate determination GO:0048867 1 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.027
myeloid cell homeostasis GO:0002262 56 0.027
dorsal ventral axis specification GO:0009950 14 0.027
regulation of canonical wnt signaling pathway GO:0060828 34 0.027
cellular response to endogenous stimulus GO:0071495 68 0.027
multi organism process GO:0051704 134 0.027
Worm Fly
cell fate determination GO:0001709 7 0.026
ectodermal placode development GO:0071696 37 0.026
regulation of cartilage development GO:0061035 7 0.026
cytoskeleton organization GO:0007010 96 0.026
neural crest cell development GO:0014032 62 0.026
Zebrafish
regulation of phosphorylation GO:0042325 26 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.025
circulatory system process GO:0003013 87 0.025
regulation of gastrulation GO:0010470 24 0.025
developmental process involved in reproduction GO:0003006 27 0.025
Worm
skeletal muscle organ development GO:0060538 78 0.025
nephron development GO:0072006 31 0.025
ventral spinal cord interneuron specification GO:0021521 3 0.025
inner ear receptor cell differentiation GO:0060113 29 0.025
neuroblast fate determination GO:0007400 1 0.025
bmp signaling pathway GO:0030509 52 0.024
regulation of cell projection organization GO:0031344 44 0.024
development of primary sexual characteristics GO:0045137 5 0.024
Worm
endodermal cell fate commitment GO:0001711 18 0.024
positive regulation of neuron migration GO:2001224 2 0.024
trigeminal nerve development GO:0021559 3 0.024
thalamus development GO:0021794 6 0.023
cartilage morphogenesis GO:0060536 13 0.023
protein phosphorylation GO:0006468 47 0.023
regulation of embryonic development GO:0045995 47 0.023
cellular response to retinoic acid GO:0071300 1 0.022
epiboly GO:0090504 41 0.022
regulation of neuron differentiation GO:0045664 56 0.022
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.022
positive regulation of jun kinase activity GO:0043507 2 0.022
heart formation GO:0060914 13 0.022
granulocyte differentiation GO:0030851 8 0.022
response to chemical GO:0042221 320 0.022
auditory receptor cell fate determination GO:0042668 2 0.022
pharyngeal system development GO:0060037 18 0.022
cell cycle GO:0007049 93 0.022
axon regeneration GO:0031103 14 0.021
pectoral fin development GO:0033339 50 0.021
regulation of endodermal cell differentiation GO:1903224 15 0.021
nephron epithelium development GO:0072009 16 0.021
muscle tissue development GO:0060537 110 0.021
anterior posterior axon guidance GO:0033564 5 0.021
type b pancreatic cell development GO:0003323 4 0.021
developmental cell growth GO:0048588 52 0.021
ameboidal type cell migration GO:0001667 143 0.021
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.021
cell cell signaling involved in cell fate commitment GO:0045168 12 0.021
endothelium development GO:0003158 25 0.020
reproductive structure development GO:0048608 5 0.020
Worm
kidney epithelium development GO:0072073 23 0.020
cellular component assembly GO:0022607 170 0.020
response to external stimulus GO:0009605 264 0.020
negative regulation of neural precursor cell proliferation GO:2000178 1 0.020
convergent extension GO:0060026 118 0.020
stem cell maintenance GO:0019827 4 0.020
regulation of anatomical structure size GO:0090066 33 0.020
regulation of anatomical structure morphogenesis GO:0022603 130 0.020
hindbrain morphogenesis GO:0021575 22 0.020
cellular response to stress GO:0033554 62 0.020
endodermal cell differentiation GO:0035987 19 0.019
photoreceptor cell fate commitment GO:0046552 1 0.019
morphogenesis of an epithelial sheet GO:0002011 49 0.019
positive regulation of cell development GO:0010720 25 0.019
ear development GO:0043583 127 0.019
regulation of axon extension GO:0030516 24 0.019
neurological system process GO:0050877 62 0.019
embryonic limb morphogenesis GO:0030326 2 0.019
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 3 0.018
striated muscle cell differentiation GO:0051146 129 0.018
reproductive system development GO:0061458 5 0.018
Worm
positive regulation of cell proliferation GO:0008284 15 0.018
sensory epithelium regeneration GO:0070654 14 0.018
pancreatic d cell differentiation GO:0003311 2 0.018
determination of left right asymmetry in nervous system GO:0035545 4 0.018

zic1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.241
congenital nervous system abnormality DOID:2490 0 0.237
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.035