Danio rerio

149 known processes

zic2a

zic family member 2 (odd-paired homolog, Drosophila), a

(Aliases: wu:fb26a03,zic2,fb26a03,cb851,zic2.1)

zic2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.978
cell proliferation in forebrain GO:0021846 3 0.944
cell proliferation in hindbrain GO:0021534 4 0.939
Zebrafish
embryonic organ development GO:0048568 381 0.935
brain development GO:0007420 293 0.930
camera type eye morphogenesis GO:0048593 108 0.929
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.926
Fly
neural crest cell differentiation GO:0014033 72 0.921
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.912
forebrain morphogenesis GO:0048853 6 0.910
Zebrafish
anterior posterior axis specification GO:0009948 20 0.893
Zebrafish
eye development GO:0001654 277 0.892
forebrain development GO:0030900 96 0.885
camera type eye development GO:0043010 222 0.882
tube morphogenesis GO:0035239 349 0.875
embryonic camera type eye development GO:0031076 29 0.861
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.856
neural tube development GO:0021915 62 0.854
regulation of signaling GO:0023051 235 0.839
pituitary gland development GO:0021983 16 0.833
nucleobase containing compound biosynthetic process GO:0034654 205 0.832
negative regulation of cellular process GO:0048523 283 0.815
cellular macromolecule metabolic process GO:0044260 391 0.812
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.798
eye morphogenesis GO:0048592 144 0.788
regulation of macromolecule biosynthetic process GO:0010556 225 0.784
diencephalon development GO:0021536 58 0.774
primary neural tube formation GO:0014020 1 0.774
Mouse
neuron fate commitment GO:0048663 26 0.773
Worm
regulation of metabolic process GO:0019222 359 0.730
mesenchymal cell development GO:0014031 78 0.712
regulation of macromolecule metabolic process GO:0060255 317 0.711
sensory organ morphogenesis GO:0090596 200 0.700
forebrain anterior posterior pattern specification GO:0021797 3 0.689
negative regulation of biological process GO:0048519 304 0.686
neuron differentiation GO:0030182 353 0.684
Mouse Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.683
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.674
regulation of cell differentiation GO:0045595 142 0.674
regulation of primary metabolic process GO:0080090 311 0.668
signal transduction GO:0007165 455 0.666
cell proliferation in midbrain GO:0033278 4 0.661
hindbrain development GO:0030902 91 0.660
Zebrafish
cellular biosynthetic process GO:0044249 286 0.656
anterior posterior pattern specification GO:0009952 152 0.654
Zebrafish
transcription dna templated GO:0006351 181 0.653
forebrain regionalization GO:0021871 4 0.643
regulation of nitrogen compound metabolic process GO:0051171 251 0.636
cellular macromolecule biosynthetic process GO:0034645 224 0.627
nucleic acid templated transcription GO:0097659 181 0.626
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.606
wnt signaling pathway GO:0016055 80 0.602
Zebrafish
regionalization GO:0003002 274 0.601
regulation of rna biosynthetic process GO:2001141 213 0.598
regulation of cell communication GO:0010646 232 0.595
cell surface receptor signaling pathway GO:0007166 325 0.584
negative regulation of biosynthetic process GO:0009890 55 0.573
regulation of response to stimulus GO:0048583 269 0.561
positive regulation of biological process GO:0048518 253 0.549
Mouse Fly
dorsal ventral pattern formation GO:0009953 125 0.543
mesenchymal cell differentiation GO:0048762 87 0.524
neural crest cell development GO:0014032 62 0.519
organic cyclic compound biosynthetic process GO:1901362 223 0.515
morphogenesis of an epithelium GO:0002009 333 0.505
cellular nitrogen compound metabolic process GO:0034641 290 0.497
transcription from rna polymerase ii promoter GO:0006366 80 0.490
Fly
cellular component morphogenesis GO:0032989 336 0.482
Mouse
regulation of multicellular organismal process GO:0051239 277 0.482
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.472
retina morphogenesis in camera type eye GO:0060042 79 0.470
forebrain neuron fate commitment GO:0021877 1 0.449
retina development in camera type eye GO:0060041 146 0.448
regulation of gene expression GO:0010468 265 0.448
cell motility GO:0048870 244 0.447
Fly
ventricular system development GO:0021591 12 0.421
Zebrafish
embryonic skeletal system development GO:0048706 97 0.417
embryonic viscerocranium morphogenesis GO:0048703 52 0.415
positive regulation of gene expression GO:0010628 71 0.413
Mouse Fly
skeletal system development GO:0001501 181 0.397
neuron fate specification GO:0048665 20 0.395
Worm
dna templated transcription initiation GO:0006352 1 0.390
Worm
forebrain dorsal ventral pattern formation GO:0021798 1 0.389
response to stress GO:0006950 263 0.385
regulation of cellular metabolic process GO:0031323 320 0.376
diencephalon morphogenesis GO:0048852 5 0.375
cell part morphogenesis GO:0032990 246 0.358
Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.354
Mouse Fly
nucleobase containing compound metabolic process GO:0006139 274 0.348
negative regulation of transcription dna templated GO:0045892 45 0.345
anterior head development GO:0097065 2 0.345
cellular component assembly involved in morphogenesis GO:0010927 107 0.344
cellular response to chemical stimulus GO:0070887 157 0.343
cell projection morphogenesis GO:0048858 244 0.331
Mouse
regulation of transcription dna templated GO:0006355 213 0.326
adenohypophysis development GO:0021984 15 0.321
localization of cell GO:0051674 244 0.319
Fly
midbrain hindbrain boundary development GO:0030917 23 0.316
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.316
regulation of oligodendrocyte differentiation GO:0048713 1 0.305
behavior GO:0007610 74 0.300
Worm
sensory organ development GO:0007423 393 0.291
stem cell development GO:0048864 82 0.289
stem cell differentiation GO:0048863 117 0.289
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.287
determination of left right symmetry GO:0007368 179 0.284
Zebrafish
generation of neurons GO:0048699 385 0.281
Mouse Worm
rna biosynthetic process GO:0032774 181 0.277
segment polarity determination GO:0007367 1 0.274
response to organic substance GO:0010033 153 0.273
midbrain development GO:0030901 28 0.270
inner ear development GO:0048839 126 0.265
connective tissue development GO:0061448 99 0.263
abducens nucleus development GO:0021742 2 0.261
regulation of biological quality GO:0065008 263 0.260
Worm
embryonic organ morphogenesis GO:0048562 274 0.252
heart field specification GO:0003128 1 0.249
epithelial tube formation GO:0072175 19 0.248
neuron projection guidance GO:0097485 86 0.246
Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.246
brain morphogenesis GO:0048854 18 0.245
Zebrafish
ear morphogenesis GO:0042471 64 0.244
embryonic camera type eye morphogenesis GO:0048596 19 0.240
nuclear transport GO:0051169 4 0.235
biosynthetic process GO:0009058 294 0.233
cell fate commitment GO:0045165 99 0.226
Worm
cell fate specification GO:0001708 68 0.225
Worm
ectodermal placode formation GO:0060788 26 0.220
organic substance biosynthetic process GO:1901576 289 0.214
cartilage development GO:0051216 96 0.213
negative regulation of nucleic acid templated transcription GO:1903507 45 0.208
positive regulation of transcription dna templated GO:0045893 57 0.202
Mouse Fly
single organism reproductive process GO:0044702 40 0.198
Worm Fly
regulation of rna metabolic process GO:0051252 224 0.195
axis specification GO:0009798 43 0.195
Zebrafish
gene expression GO:0010467 252 0.190
inner ear morphogenesis GO:0042472 63 0.188
kidney development GO:0001822 92 0.184
aromatic compound biosynthetic process GO:0019438 217 0.175
mesoderm morphogenesis GO:0048332 51 0.171
negative regulation of metabolic process GO:0009892 86 0.171
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.167
negative regulation of rna biosynthetic process GO:1902679 45 0.165
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.163
Mouse Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.162
Mouse Fly
mesenchyme development GO:0060485 127 0.159
fin development GO:0033333 77 0.158
otic vesicle morphogenesis GO:0071600 34 0.156
embryonic cranial skeleton morphogenesis GO:0048701 90 0.155
rostrocaudal neural tube patterning GO:0021903 29 0.154
metencephalon development GO:0022037 27 0.153
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.151
multi organism process GO:0051704 134 0.148
Worm Fly
negative regulation of cellular metabolic process GO:0031324 77 0.144
spinal cord development GO:0021510 46 0.143
Zebrafish
cardioblast migration GO:0003260 7 0.140
neuron development GO:0048666 262 0.140
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.139
pancreas development GO:0031016 84 0.134
protein import into nucleus GO:0006606 3 0.133
oligodendrocyte differentiation GO:0048709 23 0.132
heterocycle biosynthetic process GO:0018130 215 0.130
ear development GO:0043583 127 0.130
digestive system development GO:0055123 289 0.129
Fly
regulation of wnt signaling pathway GO:0030111 53 0.128
negative regulation of cellular biosynthetic process GO:0031327 55 0.127
nitrogen compound metabolic process GO:0006807 319 0.125
determination of pancreatic left right asymmetry GO:0035469 11 0.125
appendage development GO:0048736 80 0.125
retinal pigment epithelium development GO:0003406 8 0.124
dorsal ventral axis specification GO:0009950 14 0.119
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.118
Mouse Fly
positive regulation of rna biosynthetic process GO:1902680 57 0.116
Mouse Fly
heart formation GO:0060914 13 0.111
embryonic eye morphogenesis GO:0048048 30 0.105
negative regulation of rna metabolic process GO:0051253 48 0.100
ectodermal placode development GO:0071696 37 0.100
otic vesicle development GO:0071599 42 0.099
fourth ventricle development GO:0021592 8 0.097
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.096
protein acylation GO:0043543 3 0.095
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.094
neural tube patterning GO:0021532 33 0.094
convergent extension GO:0060026 118 0.094
heterocycle metabolic process GO:0046483 290 0.094
cellular response to organic substance GO:0071310 105 0.091
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 6 0.091
regulation of endodermal cell fate specification GO:0042663 15 0.091
palate development GO:0060021 8 0.088
cell migration GO:0016477 237 0.088
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.087
embryonic pectoral fin morphogenesis GO:0035118 24 0.085
pectoral fin development GO:0033339 50 0.084
cellular response to growth factor stimulus GO:0071363 39 0.084
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.081
regulation of developmental process GO:0050793 247 0.080
cellular component movement GO:0006928 335 0.078
Mouse Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.076
Mouse Fly
nephron morphogenesis GO:0072028 2 0.076
tube closure GO:0060606 1 0.073
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.073
canonical wnt signaling pathway GO:0060070 48 0.072
Zebrafish
response to chemical GO:0042221 320 0.071
Mouse
embryonic epithelial tube formation GO:0001838 17 0.070
protein targeting to nucleus GO:0044744 3 0.069
determination of liver left right asymmetry GO:0071910 11 0.069
anterior commissure morphogenesis GO:0021960 3 0.069
mammillary body development GO:0021767 4 0.068
tube formation GO:0035148 25 0.067
peripheral nervous system development GO:0007422 55 0.066
regulation of embryonic development GO:0045995 47 0.065
regulation of signal transduction GO:0009966 225 0.064
nucleocytoplasmic transport GO:0006913 4 0.064
regulation of cell proliferation GO:0042127 37 0.063
hepaticobiliary system development GO:0061008 98 0.063
regulation of cell migration GO:0030334 40 0.063
development of primary female sexual characteristics GO:0046545 4 0.062
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.062
Mouse
retinal cell programmed cell death GO:0046666 2 0.062
regulation of cell activation GO:0050865 1 0.061
germ cell migration GO:0008354 8 0.061
Fly
positive regulation of non canonical wnt signaling pathway GO:2000052 3 0.060
cell migration to the midline involved in heart development GO:0003318 12 0.060
thalamus development GO:0021794 6 0.058
forebrain generation of neurons GO:0021872 14 0.058
ectodermal placode morphogenesis GO:0071697 32 0.058
neural tube formation GO:0001841 16 0.058
segmentation GO:0035282 97 0.057
convergent extension involved in organogenesis GO:0060029 10 0.056
positive regulation of cellular process GO:0048522 201 0.056
Mouse Fly
determination of left right asymmetry in nervous system GO:0035545 4 0.056
gastrulation GO:0007369 208 0.055
pectoral fin morphogenesis GO:0035138 29 0.055
skeletal system morphogenesis GO:0048705 102 0.054
single organism nuclear import GO:1902593 3 0.054
eye photoreceptor cell development GO:0042462 30 0.054
cerebellum morphogenesis GO:0021587 10 0.054
regulation of protein localization to nucleus GO:1900180 2 0.053
neural crest cell migration GO:0001755 42 0.053
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.052
intracellular transport GO:0046907 32 0.051
regulation of endodermal cell differentiation GO:1903224 15 0.051
epithelial tube morphogenesis GO:0060562 148 0.051
regulation of cell motility GO:2000145 46 0.050
ameboidal type cell migration GO:0001667 143 0.050
rna metabolic process GO:0016070 219 0.050
muscle structure development GO:0061061 196 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.049
Mouse Fly
response to endogenous stimulus GO:0009719 83 0.049
single organism organelle organization GO:1902589 199 0.048
thermosensory behavior GO:0040040 1 0.048
positive regulation of rna metabolic process GO:0051254 59 0.048
Mouse Fly
neuron projection development GO:0031175 180 0.047
Mouse
neural crest formation GO:0014029 14 0.047
multicellular organism growth GO:0035264 4 0.046
rhombomere 6 development GO:0021572 4 0.046
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.046
neural plate regionalization GO:0060897 10 0.046
rhombomere development GO:0021546 19 0.046
larval development GO:0002164 2 0.046
Worm
protein metabolic process GO:0019538 183 0.046
macromolecule biosynthetic process GO:0009059 227 0.045
forebrain neuron development GO:0021884 7 0.045
head development GO:0060322 303 0.045
response to wounding GO:0009611 116 0.045
kupffer s vesicle development GO:0070121 50 0.045
nuclear import GO:0051170 3 0.045
negative regulation of response to stimulus GO:0048585 104 0.044
protein modification process GO:0036211 100 0.044
reproductive process GO:0022414 40 0.044
Worm Fly
regulation of inner ear receptor cell differentiation GO:2000980 1 0.044
neural precursor cell proliferation GO:0061351 20 0.043
regulation of binding GO:0051098 3 0.043
maintenance of location GO:0051235 4 0.043
Worm
pons development GO:0021548 11 0.042
bmp signaling pathway GO:0030509 52 0.042
determination of bilateral symmetry GO:0009855 204 0.042
Zebrafish
developmental growth GO:0048589 166 0.041
digestive tract development GO:0048565 265 0.041
Fly
cartilage morphogenesis GO:0060536 13 0.041
nucleic acid metabolic process GO:0090304 244 0.041
phosphorus metabolic process GO:0006793 109 0.040
positive regulation of biosynthetic process GO:0009891 68 0.040
Mouse Fly
midbrain hindbrain boundary morphogenesis GO:0021555 5 0.040
regulation of stem cell proliferation GO:0072091 2 0.039
regulation of axon guidance GO:1902667 8 0.039
embryonic pattern specification GO:0009880 44 0.039
cell morphogenesis involved in differentiation GO:0000904 195 0.039
Mouse
neuron projection morphogenesis GO:0048812 161 0.039
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.039
Mouse Fly
fin regeneration GO:0031101 51 0.039
organic cyclic compound metabolic process GO:1901360 301 0.039
locomotion GO:0040011 313 0.039
Mouse Worm Fly
sensory epithelium regeneration GO:0070654 14 0.039
neuroepithelial cell differentiation GO:0060563 26 0.038
organ formation GO:0048645 17 0.037
compound eye development GO:0048749 2 0.037
cell projection organization GO:0030030 284 0.037
Mouse
bone morphogenesis GO:0060349 11 0.037
neural crest cell fate commitment GO:0014034 5 0.036
cellular protein modification process GO:0006464 100 0.036
response to growth factor GO:0070848 39 0.036
developmental process involved in reproduction GO:0003006 27 0.036
Worm
pigmentation GO:0043473 85 0.036
Mouse
photoreceptor cell development GO:0042461 40 0.035
central nervous system myelin formation GO:0032289 1 0.035
photoreceptor cell fate commitment GO:0046552 1 0.034
phosphate containing compound metabolic process GO:0006796 108 0.034
rhombomere 5 development GO:0021571 4 0.034
thrombocyte differentiation GO:0002574 4 0.033
regulation of locomotion GO:0040012 55 0.033
regulation of transcription involved in cell fate commitment GO:0060850 1 0.033
erk1 and erk2 cascade GO:0070371 4 0.032
positive regulation of developmental process GO:0051094 50 0.032
intramembranous ossification GO:0001957 3 0.032
liver development GO:0001889 96 0.031
regulation of protein targeting GO:1903533 2 0.031
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.031
embryonic digestive tract morphogenesis GO:0048557 3 0.031
heart looping GO:0001947 94 0.031
specification of symmetry GO:0009799 204 0.030
Zebrafish
telencephalon development GO:0021537 14 0.029
tissue regeneration GO:0042246 74 0.029
programmed cell death GO:0012501 119 0.029
response to carbohydrate GO:0009743 3 0.029
negative regulation of phosphate metabolic process GO:0045936 13 0.028
gland development GO:0048732 143 0.028
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.028
positive regulation of stem cell proliferation GO:2000648 1 0.028
positive regulation of cell communication GO:0010647 56 0.027
renal system development GO:0072001 94 0.027
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.027
nephron tubule epithelial cell differentiation GO:0072160 1 0.026
regulation of anterior head development GO:2000742 2 0.026
cell proliferation GO:0008283 80 0.026
immune system process GO:0002376 241 0.026
mesodermal cell fate specification GO:0007501 12 0.026
spinal cord association neuron differentiation GO:0021527 1 0.026
regulation of glial cell differentiation GO:0045685 4 0.025
determination of dorsal ventral asymmetry GO:0048262 34 0.025
homeostatic process GO:0042592 142 0.025
locomotory behavior GO:0007626 34 0.025
atrioventricular valve morphogenesis GO:0003181 6 0.025
response to fibroblast growth factor GO:0071774 22 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.025
negative regulation of gene expression GO:0010629 65 0.024
macromolecule modification GO:0043412 111 0.024
response to external stimulus GO:0009605 264 0.024
Mouse
establishment of protein localization to organelle GO:0072594 4 0.024
oligodendrocyte cell fate specification GO:0021778 4 0.024
lipid storage GO:0019915 1 0.024
Worm
forebrain neuron differentiation GO:0021879 14 0.023
regeneration GO:0031099 91 0.023
positive regulation of wnt signaling pathway GO:0030177 13 0.023
cell differentiation in spinal cord GO:0021515 40 0.023
axon extension involved in axon guidance GO:0048846 10 0.023
hard palate development GO:0060022 4 0.022
morphogenesis of embryonic epithelium GO:0016331 30 0.022
nephron epithelium morphogenesis GO:0072088 1 0.022
skin development GO:0043588 54 0.022
regulation of protein import into nucleus GO:0042306 2 0.022
renal tubule morphogenesis GO:0061333 1 0.022
epidermal cell fate specification GO:0009957 4 0.021
adult behavior GO:0030534 2 0.021
mesodermal cell fate commitment GO:0001710 14 0.021
regulation of biosynthetic process GO:0009889 250 0.021
cell morphogenesis GO:0000902 289 0.021
Mouse
embryonic heart tube development GO:0035050 133 0.020
locus ceruleus development GO:0021703 3 0.020
negative regulation of phosphorus metabolic process GO:0010563 13 0.020
neural plate pattern specification GO:0060896 12 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
embryonic appendage morphogenesis GO:0035113 30 0.020
aging GO:0007568 2 0.020
gliogenesis GO:0042063 45 0.019
phosphorylation GO:0016310 69 0.019
limbic system development GO:0021761 16 0.019
ventral spinal cord interneuron fate commitment GO:0060579 3 0.019
pancreatic a cell development GO:0003322 2 0.019
determination of heart left right asymmetry GO:0061371 117 0.018
protein import GO:0017038 3 0.018
regulation of catalytic activity GO:0050790 55 0.018
endodermal cell fate determination GO:0007493 2 0.018
otic placode formation GO:0043049 23 0.018
regulation of phosphorylation GO:0042325 26 0.017
wound healing GO:0042060 90 0.017
cellular protein metabolic process GO:0044267 129 0.017
response to oxygen containing compound GO:1901700 55 0.017
regulation of phosphorus metabolic process GO:0051174 43 0.017
digestive tract morphogenesis GO:0048546 231 0.017
regulation of nervous system development GO:0051960 90 0.017
regulation of canonical wnt signaling pathway GO:0060828 34 0.017
optic placode formation GO:0001743 4 0.017
negative regulation of wnt signaling pathway GO:0030178 30 0.017
endocardial progenitor cell migration to the midline involved in heart field formation GO:0003262 4 0.017
cerebellar cortex development GO:0021695 5 0.017
optic placode formation involved in camera type eye formation GO:0046619 3 0.017
iris morphogenesis GO:0061072 1 0.016
mesodermal cell differentiation GO:0048333 21 0.016
negative regulation of cell differentiation GO:0045596 46 0.016
endodermal cell differentiation GO:0035987 19 0.016
regulation of gastrulation GO:0010470 24 0.016
response to monosaccharide GO:0034284 3 0.016
epithelial to mesenchymal transition GO:0001837 21 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.016
cell migration involved in heart formation GO:0060974 10 0.016
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.015
proximal distal pattern formation GO:0009954 1 0.015
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
central nervous system neuron differentiation GO:0021953 74 0.015
cerebellum development GO:0021549 17 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
myeloid cell differentiation GO:0030099 86 0.014
regulation of catenin import into nucleus GO:0035412 2 0.014
olfactory lobe development GO:0021988 4 0.014
regulation of programmed cell death GO:0043067 101 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
brain segmentation GO:0035284 6 0.014
morphogenesis of an epithelial sheet GO:0002011 49 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
gastrulation with mouth forming second GO:0001702 44 0.014
anterior posterior axon guidance GO:0033564 5 0.014
specification of organ identity GO:0010092 2 0.014
cellular component biogenesis GO:0044085 178 0.014
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.013
regulation of cellular response to growth factor stimulus GO:0090287 35 0.013
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
spinal cord dorsal ventral patterning GO:0021513 5 0.013
otic vesicle formation GO:0030916 27 0.013
abducens nerve development GO:0021560 1 0.013
hypothalamus development GO:0021854 14 0.013
erythrocyte homeostasis GO:0034101 55 0.013
somite specification GO:0001757 12 0.013
positive regulation of response to stimulus GO:0048584 80 0.013
cell cell signaling involved in cell fate commitment GO:0045168 12 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
semicircular canal development GO:0060872 24 0.013
regulation of cartilage development GO:0061035 7 0.013
neural crest cell fate specification GO:0014036 5 0.013
chordate embryonic development GO:0043009 271 0.013
fin morphogenesis GO:0033334 53 0.013
neural plate anterior posterior regionalization GO:0021999 8 0.013
convergent extension involved in axis elongation GO:0060028 26 0.013
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.013
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.012
nephron development GO:0072006 31 0.012
peptide transport GO:0015833 1 0.012
regulation of biomineral tissue development GO:0070167 2 0.012
single organism metabolic process GO:0044710 217 0.012
lateral inhibition GO:0046331 1 0.012
dopaminergic neuron differentiation GO:0071542 14 0.012
cardiac chamber morphogenesis GO:0003206 12 0.012
positive regulation of glial cell differentiation GO:0045687 1 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.012
Fly
sequestering of metal ion GO:0051238 3 0.012
death GO:0016265 121 0.012
positive regulation of cell cycle GO:0045787 3 0.012
protein localization to nucleus GO:0034504 3 0.012
formation of primary germ layer GO:0001704 62 0.012
axon extension GO:0048675 45 0.012
developmental growth involved in morphogenesis GO:0060560 86 0.012
posterior lateral line system development GO:0048915 46 0.012
notochord development GO:0030903 54 0.012
regulation of chondrocyte differentiation GO:0032330 1 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.011
spinal cord anterior posterior patterning GO:0021512 1 0.011
inner ear receptor cell development GO:0060119 20 0.011
cellular response to stress GO:0033554 62 0.011
sympathetic nervous system development GO:0048485 3 0.011
limb development GO:0060173 8 0.011
ventral spinal cord interneuron specification GO:0021521 3 0.011
regulation of cellular component movement GO:0051270 55 0.011
fibril organization GO:0097435 1 0.011
angioblast cell migration GO:0035476 9 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
endodermal digestive tract morphogenesis GO:0061031 2 0.011
gall bladder development GO:0061010 1 0.011
chemotaxis GO:0006935 104 0.011
Mouse
hepatic duct development GO:0061011 2 0.011
immune system development GO:0002520 191 0.011
positive regulation of cell division GO:0051781 2 0.011
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.011

zic2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.296
Human
sensory system disease DOID:0050155 0 0.069
disease of anatomical entity DOID:7 0 0.069
eye and adnexa disease DOID:1492 0 0.069
nervous system disease DOID:863 0 0.069
eye disease DOID:5614 0 0.069
bone development disease DOID:0080006 0 0.034
bone disease DOID:0080001 0 0.034
dysostosis DOID:1934 0 0.034
musculoskeletal system disease DOID:17 0 0.034
connective tissue disease DOID:65 0 0.034
microphthalmia DOID:10629 0 0.017
osteochondrodysplasia DOID:2256 0 0.014
cleidocranial dysplasia DOID:13994 0 0.014