Danio rerio

20 known processes

zic4

zic family member 4

(Aliases: fj36d02,MGC154123,zgc:154123,wu:fj36d02)

zic4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.964
cell fate commitment GO:0045165 99 0.918
Worm
dna templated transcription initiation GO:0006352 1 0.904
Worm
cell proliferation in forebrain GO:0021846 3 0.904
Zebrafish
neural tube development GO:0021915 62 0.864
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.848
Zebrafish Worm Fly
regulation of biosynthetic process GO:0009889 250 0.845
Zebrafish Fly
negative regulation of cellular process GO:0048523 283 0.815
Zebrafish
neuron development GO:0048666 262 0.755
determination of bilateral symmetry GO:0009855 204 0.752
Zebrafish
forebrain morphogenesis GO:0048853 6 0.749
Zebrafish
sensory organ development GO:0007423 393 0.748
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.734
Zebrafish Worm Fly
brain morphogenesis GO:0048854 18 0.721
Zebrafish
larval development GO:0002164 2 0.702
Worm
cell fate specification GO:0001708 68 0.698
Worm
cell migration GO:0016477 237 0.684
Fly
cell proliferation in hindbrain GO:0021534 4 0.680
regulation of cellular metabolic process GO:0031323 320 0.669
Zebrafish Fly
neuron fate specification GO:0048665 20 0.653
Worm
generation of neurons GO:0048699 385 0.646
Worm
regulation of primary metabolic process GO:0080090 311 0.640
Zebrafish Fly
chordate embryonic development GO:0043009 271 0.634
Zebrafish
heterocycle metabolic process GO:0046483 290 0.623
Zebrafish Worm Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.616
Zebrafish Fly
cell proliferation in midbrain GO:0033278 4 0.610
Zebrafish
neuron differentiation GO:0030182 353 0.601
Worm
rna biosynthetic process GO:0032774 181 0.567
Zebrafish Worm Fly
cellular biosynthetic process GO:0044249 286 0.545
Zebrafish Worm Fly
embryonic organ morphogenesis GO:0048562 274 0.532
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.514
Zebrafish Fly
specification of symmetry GO:0009799 204 0.513
Zebrafish
digestive system development GO:0055123 289 0.503
Fly
dorsal ventral pattern formation GO:0009953 125 0.478
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.475
Zebrafish Worm Fly
camera type eye development GO:0043010 222 0.467
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.462
Zebrafish Worm Fly
regulation of gene expression GO:0010468 265 0.462
Zebrafish Fly
positive regulation of biological process GO:0048518 253 0.452
Fly
neuron fate commitment GO:0048663 26 0.445
Worm
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.439
Fly
regulation of biological quality GO:0065008 263 0.431
Worm
regulation of smoothened signaling pathway GO:0008589 18 0.415
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.403
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.401
Zebrafish Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.385
Fly
positive regulation of biosynthetic process GO:0009891 68 0.375
Fly
skeletal system development GO:0001501 181 0.370
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.366
Zebrafish Worm Fly
regulation of response to stimulus GO:0048583 269 0.361
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.361
Zebrafish Worm Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.359
Zebrafish Worm Fly
gene expression GO:0010467 252 0.356
Zebrafish Worm Fly
astrocyte differentiation GO:0048708 1 0.348
ventricular system development GO:0021591 12 0.343
negative regulation of biological process GO:0048519 304 0.335
Zebrafish
embryonic organ development GO:0048568 381 0.325
Zebrafish
neural precursor cell proliferation GO:0061351 20 0.324
cellular macromolecule biosynthetic process GO:0034645 224 0.320
Zebrafish Worm Fly
cell proliferation GO:0008283 80 0.317
regulation of nitrogen compound metabolic process GO:0051171 251 0.315
Zebrafish Fly
morphogenesis of an epithelium GO:0002009 333 0.314
Zebrafish
midbrain development GO:0030901 28 0.313
Zebrafish
regulation of cell communication GO:0010646 232 0.309
Zebrafish
brain development GO:0007420 293 0.308
cellular aromatic compound metabolic process GO:0006725 295 0.304
Zebrafish Worm Fly
determination of heart left right asymmetry GO:0061371 117 0.302
gliogenesis GO:0042063 45 0.298
regulation of multicellular organismal development GO:2000026 223 0.296
neuron projection development GO:0031175 180 0.295
regulation of cellular biosynthetic process GO:0031326 245 0.291
Zebrafish Fly
retina morphogenesis in camera type eye GO:0060042 79 0.279
Zebrafish
transcription dna templated GO:0006351 181 0.275
Zebrafish Worm Fly
lipid storage GO:0019915 1 0.273
Worm
mechanoreceptor differentiation GO:0042490 37 0.272
heart development GO:0007507 313 0.266
retina development in camera type eye GO:0060041 146 0.264
Zebrafish
abducens nucleus development GO:0021742 2 0.263
axon guidance GO:0007411 86 0.261
cell projection organization GO:0030030 284 0.261
tube morphogenesis GO:0035239 349 0.261
Zebrafish
positive regulation of cellular process GO:0048522 201 0.256
Fly
axon development GO:0061564 166 0.255
nucleic acid templated transcription GO:0097659 181 0.255
Zebrafish Worm Fly
embryonic viscerocranium morphogenesis GO:0048703 52 0.254
Zebrafish
signal transduction GO:0007165 455 0.251
Zebrafish Fly
head development GO:0060322 303 0.251
regulation of neurogenesis GO:0050767 87 0.249
rna metabolic process GO:0016070 219 0.246
Zebrafish Worm Fly
cell projection morphogenesis GO:0048858 244 0.239
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.237
Zebrafish Fly
regulation of cell differentiation GO:0045595 142 0.235
neural tube formation GO:0001841 16 0.234
Zebrafish
eye development GO:0001654 277 0.234
Zebrafish
cellular component movement GO:0006928 335 0.234
Fly
regulation of signaling GO:0023051 235 0.230
Zebrafish
stem cell development GO:0048864 82 0.225
Zebrafish
cell part morphogenesis GO:0032990 246 0.224
regulation of rna metabolic process GO:0051252 224 0.224
Zebrafish Fly
negative regulation of gliogenesis GO:0014014 1 0.221
regulation of metabolic process GO:0019222 359 0.219
Zebrafish Fly
regulation of dendrite morphogenesis GO:0048814 3 0.217
locomotion GO:0040011 313 0.216
Worm Fly
neuron projection guidance GO:0097485 86 0.214
stem cell differentiation GO:0048863 117 0.209
Zebrafish
biosynthetic process GO:0009058 294 0.209
Zebrafish Worm Fly
neuron projection morphogenesis GO:0048812 161 0.206
regulation of neuron projection development GO:0010975 40 0.204
heart morphogenesis GO:0003007 156 0.202
determination of left right symmetry GO:0007368 179 0.199
Zebrafish
neural crest cell differentiation GO:0014033 72 0.198
Zebrafish
spinal cord development GO:0021510 46 0.195
Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.193
Zebrafish Worm Fly
fourth ventricle development GO:0021592 8 0.191
positive regulation of gene expression GO:0010628 71 0.190
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.189
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.188
Fly
germ cell migration GO:0008354 8 0.184
Fly
axonogenesis GO:0007409 152 0.183
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.181
embryo development ending in birth or egg hatching GO:0009792 271 0.172
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.166
Zebrafish Worm Fly
embryonic cranial skeleton morphogenesis GO:0048701 90 0.163
Zebrafish
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.161
Zebrafish
neuroblast proliferation GO:0007405 2 0.157
regulation of multicellular organismal process GO:0051239 277 0.157
ameboidal type cell migration GO:0001667 143 0.153
forebrain anterior posterior pattern specification GO:0021797 3 0.151
wnt signaling pathway GO:0016055 80 0.151
Zebrafish
regionalization GO:0003002 274 0.149
Zebrafish
central nervous system neuron axonogenesis GO:0021955 18 0.149
negative regulation of cellular metabolic process GO:0031324 77 0.144
Zebrafish
positive regulation of cellular biosynthetic process GO:0031328 68 0.143
Fly
aromatic compound biosynthetic process GO:0019438 217 0.138
Zebrafish Worm Fly
regulation of nervous system development GO:0051960 90 0.138
regulation of transcription dna templated GO:0006355 213 0.138
Zebrafish Fly
positive regulation of metabolic process GO:0009893 108 0.137
Fly
diencephalon development GO:0021536 58 0.137
Zebrafish
synaptic transmission GO:0007268 35 0.133
behavior GO:0007610 74 0.132
Worm
negative regulation of gene expression GO:0010629 65 0.129
Zebrafish
camera type eye morphogenesis GO:0048593 108 0.128
Zebrafish
hindbrain development GO:0030902 91 0.127
negative regulation of cellular biosynthetic process GO:0031327 55 0.126
Zebrafish
cell motility GO:0048870 244 0.125
Fly
positive regulation of rna metabolic process GO:0051254 59 0.124
Fly
epithelial tube morphogenesis GO:0060562 148 0.121
Zebrafish
forebrain development GO:0030900 96 0.121
Zebrafish
maintenance of location GO:0051235 4 0.120
Worm
cell morphogenesis involved in differentiation GO:0000904 195 0.119
cellular component morphogenesis GO:0032989 336 0.118
ventral spinal cord interneuron fate commitment GO:0060579 3 0.116
regulation of stem cell proliferation GO:0072091 2 0.115
neural crest cell development GO:0014032 62 0.112
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.109
Zebrafish Fly
glial cell differentiation GO:0010001 42 0.108
pancreas development GO:0031016 84 0.107
primary neural tube formation GO:0014020 1 0.103
reproductive process GO:0022414 40 0.102
Worm Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.100
Zebrafish Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.100
Zebrafish Worm Fly
negative regulation of metabolic process GO:0009892 86 0.100
Zebrafish
embryonic skeletal system development GO:0048706 97 0.099
Zebrafish
positive regulation of nucleic acid templated transcription GO:1903508 57 0.095
Fly
regulation of signal transduction GO:0009966 225 0.095
Zebrafish
neuron migration GO:0001764 22 0.095
mesenchymal cell differentiation GO:0048762 87 0.094
Zebrafish
sensory organ morphogenesis GO:0090596 200 0.092
Zebrafish
central nervous system neuron development GO:0021954 29 0.091
appendage development GO:0048736 80 0.091
cell differentiation in spinal cord GO:0021515 40 0.090
glial cell migration GO:0008347 3 0.086
developmental pigmentation GO:0048066 48 0.086
endodermal cell fate determination GO:0007493 2 0.086
negative regulation of nucleic acid templated transcription GO:1903507 45 0.085
Zebrafish
neuron fate determination GO:0048664 2 0.084
cell surface receptor signaling pathway GO:0007166 325 0.084
Zebrafish Fly
system process GO:0003008 185 0.083
epidermal cell fate specification GO:0009957 4 0.082
stem cell proliferation GO:0072089 4 0.082
embryonic heart tube morphogenesis GO:0003143 108 0.078
multicellular organismal reproductive process GO:0048609 35 0.078
Worm Fly
localization of cell GO:0051674 244 0.078
Fly
ventral spinal cord development GO:0021517 35 0.077
inner ear receptor cell differentiation GO:0060113 29 0.077
neuroblast fate determination GO:0007400 1 0.076
regulation of neuron differentiation GO:0045664 56 0.075
fin development GO:0033333 77 0.074
pectoral fin morphogenesis GO:0035138 29 0.074
negative regulation of macromolecule metabolic process GO:0010605 76 0.073
Zebrafish
epithelial tube formation GO:0072175 19 0.073
Zebrafish
morphogenesis of embryonic epithelium GO:0016331 30 0.071
Zebrafish
negative regulation of biosynthetic process GO:0009890 55 0.071
Zebrafish
transmission of nerve impulse GO:0019226 19 0.071
positive regulation of transcription dna templated GO:0045893 57 0.069
Fly
autonomic nervous system development GO:0048483 19 0.069
oligodendrocyte differentiation GO:0048709 23 0.069
embryonic heart tube development GO:0035050 133 0.069
regulation of cell development GO:0060284 100 0.069
embryonic epithelial tube formation GO:0001838 17 0.068
Zebrafish
taxis GO:0042330 109 0.068
cell morphogenesis GO:0000902 289 0.068
heterocycle biosynthetic process GO:0018130 215 0.068
Zebrafish Worm Fly
central nervous system neuron differentiation GO:0021953 74 0.067
canonical wnt signaling pathway GO:0060070 48 0.066
Zebrafish
regulation of neural precursor cell proliferation GO:2000177 3 0.065
embryonic skeletal system morphogenesis GO:0048704 93 0.064
Zebrafish
establishment of localization GO:0051234 244 0.063
ventral spinal cord interneuron differentiation GO:0021514 12 0.062
negative regulation of transcription dna templated GO:0045892 45 0.062
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.061
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.061
Zebrafish
regulation of endodermal cell fate specification GO:0042663 15 0.061
positive regulation of neural precursor cell proliferation GO:2000179 1 0.060
neuroepithelial cell differentiation GO:0060563 26 0.059
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.059
Fly
embryonic pectoral fin morphogenesis GO:0035118 24 0.058
eye morphogenesis GO:0048592 144 0.058
Zebrafish
blood circulation GO:0008015 87 0.056
regulation of heart contraction GO:0008016 32 0.056
melanocyte differentiation GO:0030318 26 0.055
neuronal action potential GO:0019228 18 0.054
regulation of developmental process GO:0050793 247 0.054
response to stress GO:0006950 263 0.054
negative regulation of multicellular organismal process GO:0051241 69 0.054
regeneration GO:0031099 91 0.053
oligodendrocyte cell fate specification GO:0021778 4 0.053
mesenchymal cell development GO:0014031 78 0.053
Zebrafish
hepaticobiliary system development GO:0061008 98 0.053
multicellular organism reproduction GO:0032504 35 0.053
Worm Fly
anterior commissure morphogenesis GO:0021960 3 0.052
circulatory system process GO:0003013 87 0.051
negative regulation of rna biosynthetic process GO:1902679 45 0.050
Zebrafish
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.050
forebrain neuron fate commitment GO:0021877 1 0.050
regulation of wnt signaling pathway GO:0030111 53 0.049
pectoral fin development GO:0033339 50 0.048
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.048
Zebrafish
sympathetic nervous system development GO:0048485 3 0.048
regulation of binding GO:0051098 3 0.048
growth GO:0040007 174 0.048
positive regulation of rna biosynthetic process GO:1902680 57 0.048
Fly
negative regulation of rna metabolic process GO:0051253 48 0.047
Zebrafish
axon ensheathment GO:0008366 18 0.047
limbic system development GO:0021761 16 0.046
response to external stimulus GO:0009605 264 0.046
neuroblast fate commitment GO:0014017 1 0.046
regulation of dendrite development GO:0050773 3 0.046
central nervous system myelination GO:0022010 2 0.046
multi organism process GO:0051704 134 0.044
Worm Fly
nitrogen compound metabolic process GO:0006807 319 0.044
Zebrafish Worm Fly
regulation of glial cell differentiation GO:0045685 4 0.042
neuron neuron synaptic transmission GO:0007270 1 0.041
olfactory lobe development GO:0021988 4 0.041
telencephalon development GO:0021537 14 0.041
forebrain regionalization GO:0021871 4 0.041
atrioventricular valve formation GO:0003190 3 0.040
regulation of blood circulation GO:1903522 32 0.039
response to chemical GO:0042221 320 0.039
ventral spinal cord interneuron specification GO:0021521 3 0.038
macromolecule modification GO:0043412 111 0.038
positive regulation of molecular function GO:0044093 33 0.038
negative regulation of neurogenesis GO:0050768 20 0.038
enzyme linked receptor protein signaling pathway GO:0007167 106 0.037
Fly
nerve development GO:0021675 45 0.037
regulation of localization GO:0032879 104 0.037
stem cell fate determination GO:0048867 1 0.037
peripheral nervous system development GO:0007422 55 0.037
mesenchyme development GO:0060485 127 0.037
Zebrafish
heart looping GO:0001947 94 0.037
inner ear receptor cell development GO:0060119 20 0.036
chemotaxis GO:0006935 104 0.035
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.035
Fly
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.035
Zebrafish
gland development GO:0048732 143 0.034
transport GO:0006810 220 0.034
multicellular organismal signaling GO:0035637 22 0.033
stem cell fate commitment GO:0048865 1 0.033
positive regulation of cell cycle GO:0045787 3 0.033
axon ensheathment in central nervous system GO:0032291 2 0.033
gastrulation with mouth forming second GO:0001702 44 0.033
regulation of endodermal cell differentiation GO:1903224 15 0.033
locomotory behavior GO:0007626 34 0.032
heart contraction GO:0060047 71 0.032
cell migration involved in gastrulation GO:0042074 79 0.032
ear development GO:0043583 127 0.032
regulation of inner ear receptor cell differentiation GO:2000980 1 0.032
myelination GO:0042552 18 0.032
determination of pancreatic left right asymmetry GO:0035469 11 0.032
spinal cord motor neuron differentiation GO:0021522 26 0.031
type b pancreatic cell development GO:0003323 4 0.031
muscle tissue development GO:0060537 110 0.031
central nervous system projection neuron axonogenesis GO:0021952 15 0.031
regulation of system process GO:0044057 40 0.030
pharyngeal muscle development GO:0043282 4 0.030
anterior posterior pattern specification GO:0009952 152 0.030
Zebrafish
cellular protein metabolic process GO:0044267 129 0.030
regulation of cell proliferation GO:0042127 37 0.029
Zebrafish
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.029
skeletal system morphogenesis GO:0048705 102 0.029
Zebrafish
appendage morphogenesis GO:0035107 56 0.029
regulation of anatomical structure morphogenesis GO:0022603 130 0.029
gabaergic neuron differentiation GO:0097154 2 0.029
peptide transport GO:0015833 1 0.028
negative regulation of cell differentiation GO:0045596 46 0.028
facial nerve development GO:0021561 3 0.028
regulation of locomotion GO:0040012 55 0.028
neuroblast differentiation GO:0014016 1 0.028
positive regulation of cellular metabolic process GO:0031325 94 0.028
Fly
wound healing GO:0042060 90 0.027
ectodermal placode morphogenesis GO:0071697 32 0.027
morphogenesis of an epithelial sheet GO:0002011 49 0.027
multicellular organism growth GO:0035264 4 0.027
regulation of oligodendrocyte differentiation GO:0048713 1 0.026
compound eye development GO:0048749 2 0.026
adult behavior GO:0030534 2 0.026
tube closure GO:0060606 1 0.025
positive regulation of map kinase activity GO:0043406 3 0.025
protein metabolic process GO:0019538 183 0.025
cellular component assembly GO:0022607 170 0.025
spinal cord association neuron differentiation GO:0021527 1 0.025
pigmentation GO:0043473 85 0.025
neural nucleus development GO:0048857 15 0.025
apoptotic process involved in morphogenesis GO:0060561 2 0.025
aging GO:0007568 2 0.024
olfactory bulb development GO:0021772 4 0.024
photoreceptor cell fate commitment GO:0046552 1 0.024
dorsal spinal cord development GO:0021516 1 0.024
single organism transport GO:0044765 206 0.024
single organism localization GO:1902578 225 0.023
negative regulation of signaling GO:0023057 96 0.023
neural tube patterning GO:0021532 33 0.023
skin development GO:0043588 54 0.023
nuclear transport GO:0051169 4 0.023
anterior posterior axis specification GO:0009948 20 0.023
Zebrafish
embryonic appendage morphogenesis GO:0035113 30 0.023
heart process GO:0003015 71 0.023
developmental growth GO:0048589 166 0.023
neural retina development GO:0003407 49 0.023
regulation of fatty acid metabolic process GO:0019217 1 0.023
startle response GO:0001964 4 0.023
phagocytosis GO:0006909 3 0.022
positive regulation of transport GO:0051050 2 0.022
digestive tract morphogenesis GO:0048546 231 0.022
liver development GO:0001889 96 0.021
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.021
mammillary body development GO:0021767 4 0.021
cellular localization GO:0051641 97 0.021
regulation of protein complex assembly GO:0043254 3 0.021
regulation of canonical wnt signaling pathway GO:0060828 34 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.021
neurological system process GO:0050877 62 0.021
membrane fusion GO:0061025 2 0.021
lipid localization GO:0010876 11 0.020
Worm
intracellular receptor signaling pathway GO:0030522 30 0.020
regulation of cellular component organization GO:0051128 86 0.020
striated muscle cell development GO:0055002 108 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.020
glial cell development GO:0021782 20 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
embryonic hemopoiesis GO:0035162 53 0.020
positive regulation of nervous system development GO:0051962 25 0.020
protein localization to nucleus GO:0034504 3 0.020
proximal distal pattern formation GO:0009954 1 0.020
pronephros development GO:0048793 69 0.020
endothelial cell development GO:0001885 12 0.019
positive regulation of cell communication GO:0010647 56 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
muscle fiber development GO:0048747 52 0.019
positive regulation of stem cell proliferation GO:2000648 1 0.019
response to external biotic stimulus GO:0043207 97 0.019
endodermal cell fate commitment GO:0001711 18 0.019
pigment cell differentiation GO:0050931 38 0.018
cranial nerve development GO:0021545 42 0.018
neural crest cell migration GO:0001755 42 0.018
gtp metabolic process GO:0046039 4 0.018
endoderm development GO:0007492 49 0.018
ensheathment of neurons GO:0007272 18 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.018
protein import into nucleus GO:0006606 3 0.018
endothelial cell fate commitment GO:0060839 3 0.018
pancreatic a cell development GO:0003322 2 0.018
positive regulation of neuron projection regeneration GO:0070572 3 0.018
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.018
regulation of stem cell differentiation GO:2000736 4 0.017
gtp catabolic process GO:0006184 2 0.017
ear morphogenesis GO:0042471 64 0.017
cardiac chamber formation GO:0003207 4 0.017
response to other organism GO:0051707 97 0.017
regulation of cardiac chamber formation GO:1901210 2 0.017
neuron projection extension GO:1990138 45 0.017
pons development GO:0021548 11 0.017
macromolecule localization GO:0033036 54 0.017
Worm
locomotor rhythm GO:0045475 3 0.017
single organism metabolic process GO:0044710 217 0.016
phosphatidylinositol mediated signaling GO:0048015 2 0.016
vasculogenesis GO:0001570 41 0.016
endocrine pancreas development GO:0031018 27 0.016
positive regulation of jak stat cascade GO:0046427 2 0.016
inner ear development GO:0048839 126 0.016
peripheral nervous system neuron differentiation GO:0048934 28 0.016
muscle cell differentiation GO:0042692 139 0.016
nuclear import GO:0051170 3 0.016
response to wounding GO:0009611 116 0.016
positive regulation of gtp catabolic process GO:0033126 1 0.016
regulation of cell migration GO:0030334 40 0.016
lateral inhibition GO:0046331 1 0.016
cardiac muscle cell differentiation GO:0055007 30 0.016
forebrain neuron differentiation GO:0021879 14 0.016
lymphatic endothelial cell differentiation GO:0060836 1 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
neuromast mantle cell differentiation GO:0048888 1 0.016
mesodermal cell fate specification GO:0007501 12 0.015
metencephalon development GO:0022037 27 0.015
epithelial cell differentiation GO:0030855 116 0.015
facial nucleus development GO:0021754 7 0.015
female sex differentiation GO:0046660 4 0.015
endothelial cell differentiation GO:0045446 20 0.015
programmed cell death GO:0012501 119 0.015
regulation of cellular component movement GO:0051270 55 0.015
protein targeting to nucleus GO:0044744 3 0.015
sympathetic ganglion development GO:0061549 2 0.015
positive regulation of neurogenesis GO:0050769 24 0.015
immune system process GO:0002376 241 0.015
positive regulation of cell proliferation GO:0008284 15 0.015
phosphorus metabolic process GO:0006793 109 0.015
protein import GO:0017038 3 0.014
endocrine system development GO:0035270 65 0.014
kupffer s vesicle development GO:0070121 50 0.014
positive regulation of gliogenesis GO:0014015 2 0.014
stem cell maintenance GO:0019827 4 0.014
cardioblast migration GO:0003260 7 0.014
single organism organelle organization GO:1902589 199 0.014
endoderm formation GO:0001706 29 0.014
convergent extension GO:0060026 118 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
regulation of bmp signaling pathway GO:0030510 39 0.014
bmp signaling pathway GO:0030509 52 0.014
regulation of gtp catabolic process GO:0033124 2 0.014
ectodermal placode development GO:0071696 37 0.014
heart valve morphogenesis GO:0003179 8 0.014
lymphatic endothelial cell fate commitment GO:0060838 1 0.014
tissue regeneration GO:0042246 74 0.014
inner ear morphogenesis GO:0042472 63 0.014
urogenital system development GO:0001655 97 0.014
negative regulation of signal transduction GO:0009968 94 0.013
type b pancreatic cell differentiation GO:0003309 8 0.013
establishment of localization in cell GO:0051649 77 0.013
regulation of cell motility GO:2000145 46 0.013
determination of left right asymmetry in nervous system GO:0035545 4 0.013
rhombomere 4 morphogenesis GO:0021661 5 0.013
cilium morphogenesis GO:0060271 85 0.013
water homeostasis GO:0030104 4 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.013
protein modification process GO:0036211 100 0.013
negative regulation of cell communication GO:0010648 96 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
fin morphogenesis GO:0033334 53 0.013
neuron projection regeneration GO:0031102 16 0.013
tube formation GO:0035148 25 0.013
Zebrafish
multi organism reproductive process GO:0044703 36 0.013
Worm Fly
positive regulation of glial cell differentiation GO:0045687 1 0.013
negative regulation of neuron differentiation GO:0045665 10 0.013
positive regulation of catabolic process GO:0009896 4 0.012
regulation of cell fate commitment GO:0010453 22 0.012
cellular amine metabolic process GO:0044106 2 0.012
developmental process involved in reproduction GO:0003006 27 0.012
Worm
inner ear receptor cell fate commitment GO:0060120 4 0.012
retinal ganglion cell axon guidance GO:0031290 35 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.012
Zebrafish
axon extension GO:0048675 45 0.012
photoreceptor cell fate specification GO:0043704 1 0.012
epiboly GO:0090504 41 0.012
facial nerve morphogenesis GO:0021610 1 0.012
smoothened signaling pathway GO:0007224 30 0.012
Zebrafish
negative regulation of cytokine production GO:0001818 1 0.012
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.012
trigeminal nerve development GO:0021559 3 0.012
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.012
Fly
negative regulation of cell development GO:0010721 26 0.012
aorta development GO:0035904 4 0.012
defense response to fungus GO:0050832 2 0.012
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.012
lens development in camera type eye GO:0002088 22 0.012
cellular component biogenesis GO:0044085 178 0.012
cellular protein modification process GO:0006464 100 0.011
regulation of gtpase activity GO:0043087 2 0.011
intracellular signal transduction GO:0035556 85 0.011
cellular amide metabolic process GO:0043603 4 0.011
cardiac muscle tissue development GO:0048738 48 0.011
lipid metabolic process GO:0006629 52 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
somatic muscle development GO:0007525 4 0.011
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.011

zic4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.072
nervous system disease DOID:863 0 0.049
sensory system disease DOID:0050155 0 0.023
physical disorder DOID:0080015 0 0.016