|
|
eye development
|
GO:0001654 |
277 |
0.955
|
|
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.948
|
|
|
|
regionalization
|
GO:0003002 |
274 |
0.904
|
|
|
|
cellular component movement
|
GO:0006928 |
335 |
0.873
|
|
|
|
sensory organ development
|
GO:0007423 |
393 |
0.873
|
|
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.870
|
|
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.865
|
|
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.864
|
|
|
|
cell motility
|
GO:0048870 |
244 |
0.849
|
|
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.843
|
|
|
|
localization of cell
|
GO:0051674 |
244 |
0.821
|
|
|
|
positive regulation of protein deacetylation
|
GO:0090312 |
1 |
0.753
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.749
|
|
|
|
cell migration
|
GO:0016477 |
237 |
0.748
|
|
|
|
brain development
|
GO:0007420 |
293 |
0.746
|
|
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.715
|
|
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.685
|
|
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.669
|
|
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.644
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.629
|
|
|
|
signal transduction
|
GO:0007165 |
455 |
0.607
|
Human Fly |
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.605
|
|
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.591
|
|
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.569
|
|
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.567
|
|
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.561
|
Human Fly |
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.551
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.542
|
|
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.523
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.514
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.508
|
|
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.499
|
Human |
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.488
|
|
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.487
|
Human |
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.471
|
|
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.470
|
|
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.447
|
|
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.444
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.434
|
|
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.432
|
|
|
|
nuclear import
|
GO:0051170 |
3 |
0.423
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.417
|
|
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.414
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
59 |
0.405
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.392
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.385
|
|
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.368
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.364
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.353
|
Fly |
|
|
negative regulation of response to stimulus
|
GO:0048585 |
104 |
0.352
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
114 |
0.351
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.350
|
Human |
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.343
|
|
|
|
neural tube development
|
GO:0021915 |
62 |
0.343
|
|
|
|
gene expression
|
GO:0010467 |
252 |
0.341
|
|
|
|
generation of neurons
|
GO:0048699 |
385 |
0.339
|
Fly |
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.335
|
|
|
|
head development
|
GO:0060322 |
303 |
0.330
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
65 |
0.324
|
|
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.304
|
Human |
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.300
|
|
|
|
regulation of chondrocyte differentiation
|
GO:0032330 |
1 |
0.300
|
|
|
|
gastrulation
|
GO:0007369 |
208 |
0.299
|
|
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.298
|
|
|
|
somite development
|
GO:0061053 |
96 |
0.290
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.288
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
86 |
0.279
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
2 |
0.278
|
|
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.276
|
|
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.276
|
|
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.274
|
Fly |
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.273
|
|
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.273
|
|
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.268
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.262
|
Human |
|
|
embryonic eye morphogenesis
|
GO:0048048 |
30 |
0.257
|
|
|
|
rhombomere formation
|
GO:0021594 |
12 |
0.248
|
|
|
|
cardiac cell fate commitment
|
GO:0060911 |
1 |
0.230
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
4 |
0.229
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
37 |
0.224
|
Human |
|
|
skeletal system development
|
GO:0001501 |
181 |
0.220
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.209
|
|
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.207
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.207
|
Fly |
|
|
response to nutrient
|
GO:0007584 |
3 |
0.205
|
|
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.203
|
|
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.202
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.200
|
|
|
|
primary neural tube formation
|
GO:0014020 |
1 |
0.197
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.194
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.193
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
59 |
0.191
|
|
|
|
regulation of response to stress
|
GO:0080134 |
36 |
0.184
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
143 |
0.178
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
30 |
0.177
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
3 |
0.177
|
|
|
|
protein import
|
GO:0017038 |
3 |
0.174
|
|
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.172
|
Human |
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.171
|
|
|
|
apoptotic process
|
GO:0006915 |
116 |
0.168
|
|
|
|
camera type eye development
|
GO:0043010 |
222 |
0.165
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
36 |
0.161
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
78 |
0.159
|
|
|
|
chromosome organization
|
GO:0051276 |
31 |
0.159
|
|
|
|
regulation of cell development
|
GO:0060284 |
100 |
0.158
|
|
|
|
nephron development
|
GO:0072006 |
31 |
0.157
|
|
|
|
central nervous system development
|
GO:0007417 |
387 |
0.157
|
|
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.155
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.153
|
|
|
|
epidermis development
|
GO:0008544 |
48 |
0.152
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.151
|
|
|
|
neuron development
|
GO:0048666 |
262 |
0.149
|
|
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.148
|
|
|
|
digestive tract development
|
GO:0048565 |
265 |
0.146
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.146
|
|
|
|
immune system development
|
GO:0002520 |
191 |
0.145
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
48 |
0.142
|
|
|
|
neuron migration
|
GO:0001764 |
22 |
0.142
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.139
|
|
|
|
eye morphogenesis
|
GO:0048592 |
144 |
0.139
|
|
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.138
|
|
|
|
heart development
|
GO:0007507 |
313 |
0.138
|
|
|
|
aging
|
GO:0007568 |
2 |
0.136
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
39 |
0.133
|
Human |
|
|
maintenance of location
|
GO:0051235 |
4 |
0.133
|
|
|
|
cell fate specification
|
GO:0001708 |
68 |
0.132
|
|
|
|
rhombomere morphogenesis
|
GO:0021593 |
17 |
0.131
|
|
|
|
vasculature development
|
GO:0001944 |
278 |
0.131
|
|
|
|
hemopoiesis
|
GO:0030097 |
183 |
0.131
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.131
|
|
|
|
digestive system development
|
GO:0055123 |
289 |
0.130
|
|
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.130
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.129
|
|
|
|
regulation of cell activation
|
GO:0050865 |
1 |
0.128
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
1 |
0.126
|
|
|
|
chromatin modification
|
GO:0016568 |
21 |
0.126
|
|
|
|
cell fate commitment
|
GO:0045165 |
99 |
0.126
|
Fly |
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
55 |
0.124
|
|
|
|
somitogenesis
|
GO:0001756 |
87 |
0.123
|
|
|
|
neural crest formation
|
GO:0014029 |
14 |
0.122
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
29 |
0.120
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
231 |
0.120
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
142 |
0.118
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
102 |
0.117
|
|
|
|
rhombomere boundary formation
|
GO:0021654 |
10 |
0.115
|
|
|
|
cell recognition
|
GO:0008037 |
19 |
0.114
|
|
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.113
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
59 |
0.109
|
|
|
|
neuron recognition
|
GO:0008038 |
18 |
0.108
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
50 |
0.108
|
Human |
|
|
appendage development
|
GO:0048736 |
80 |
0.107
|
Fly |
|
|
foregut morphogenesis
|
GO:0007440 |
4 |
0.107
|
|
|
|
wound healing
|
GO:0042060 |
90 |
0.106
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.104
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
3 |
0.103
|
Human |
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
59 |
0.103
|
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.103
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
7 |
0.101
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
44 |
0.101
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
48 |
0.101
|
|
|
|
segmentation
|
GO:0035282 |
97 |
0.100
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
2 |
0.100
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
34 |
0.100
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.100
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
1 |
0.100
|
|
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.099
|
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.098
|
|
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.097
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.097
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.095
|
Human |
|
|
cartilage development
|
GO:0051216 |
96 |
0.094
|
|
|
|
nuclear transport
|
GO:0051169 |
4 |
0.094
|
|
|
|
cellular protein localization
|
GO:0034613 |
20 |
0.093
|
|
|
|
stem cell maintenance
|
GO:0019827 |
4 |
0.093
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.092
|
|
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.090
|
|
|
|
single organism localization
|
GO:1902578 |
225 |
0.089
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.088
|
|
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.088
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
35 |
0.087
|
|
|
|
hindbrain development
|
GO:0030902 |
91 |
0.086
|
|
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.085
|
|
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.085
|
|
|
|
regulation of catenin import into nucleus
|
GO:0035412 |
2 |
0.085
|
|
|
|
camera type eye morphogenesis
|
GO:0048593 |
108 |
0.084
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.084
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
93 |
0.083
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
71 |
0.082
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
57 |
0.082
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.081
|
|
|
|
convergent extension
|
GO:0060026 |
118 |
0.081
|
|
|
|
axonogenesis
|
GO:0007409 |
152 |
0.081
|
|
|
|
regulation of cell death
|
GO:0010941 |
103 |
0.080
|
|
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.079
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.079
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
36 |
0.078
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
216 |
0.078
|
|
|
|
muscle structure development
|
GO:0061061 |
196 |
0.078
|
|
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
1 |
0.078
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
2 |
0.078
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
44 |
0.077
|
|
|
|
cell projection organization
|
GO:0030030 |
284 |
0.077
|
|
|
|
ear morphogenesis
|
GO:0042471 |
64 |
0.077
|
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
45 |
0.074
|
|
|
|
regulation of cell migration
|
GO:0030334 |
40 |
0.073
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.073
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.072
|
|
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.072
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.072
|
|
|
|
heart field specification
|
GO:0003128 |
1 |
0.069
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
83 |
0.069
|
Human |
|
|
inner ear morphogenesis
|
GO:0042472 |
63 |
0.068
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
2 |
0.067
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
22 |
0.066
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
125 |
0.064
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.063
|
|
|
|
death
|
GO:0016265 |
121 |
0.063
|
|
|
|
cell cycle
|
GO:0007049 |
93 |
0.063
|
Human |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
16 |
0.063
|
|
|
|
response to vitamin
|
GO:0033273 |
3 |
0.062
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
7 |
0.062
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
3 |
0.062
|
|
|
|
cell migration involved in heart development
|
GO:0060973 |
22 |
0.061
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
2 |
0.061
|
|
|
|
embryonic camera type eye formation
|
GO:0060900 |
10 |
0.060
|
|
|
|
retinoic acid receptor signaling pathway
|
GO:0048384 |
16 |
0.059
|
|
|
|
aorta development
|
GO:0035904 |
4 |
0.059
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
74 |
0.059
|
|
|
|
lipid storage
|
GO:0019915 |
1 |
0.059
|
|
|
|
regulation of signal transduction by p53 class mediator
|
GO:1901796 |
9 |
0.059
|
|
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.059
|
|
|
|
protein stabilization
|
GO:0050821 |
2 |
0.059
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
8 |
0.058
|
|
|
|
regulation of binding
|
GO:0051098 |
3 |
0.057
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.057
|
Human |
|
|
endoderm formation
|
GO:0001706 |
29 |
0.056
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
68 |
0.056
|
|
|
|
reproduction
|
GO:0000003 |
40 |
0.056
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
46 |
0.056
|
|
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.055
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
53 |
0.055
|
|
|
|
convergent extension involved in organogenesis
|
GO:0060029 |
10 |
0.054
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
22 |
0.054
|
|
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.054
|
|
|
|
cellular localization
|
GO:0051641 |
97 |
0.053
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
139 |
0.053
|
|
|
|
regulation of protein binding
|
GO:0043393 |
3 |
0.053
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
1 |
0.052
|
|
|
|
growth
|
GO:0040007 |
174 |
0.052
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
3 |
0.052
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
2 |
0.052
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
62 |
0.052
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
48 |
0.051
|
|
|
|
notch signaling pathway
|
GO:0007219 |
35 |
0.051
|
Fly |
|
|
outflow tract morphogenesis
|
GO:0003151 |
1 |
0.051
|
|
|
|
heart morphogenesis
|
GO:0003007 |
156 |
0.051
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.050
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
51 |
0.050
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
3 |
0.050
|
|
|
|
rhombomere development
|
GO:0021546 |
19 |
0.049
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
3 |
0.049
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.049
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
79 |
0.049
|
|
|
|
eye field cell fate commitment involved in camera type eye formation
|
GO:0060898 |
3 |
0.048
|
|
|
|
skin development
|
GO:0043588 |
54 |
0.048
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.048
|
|
|
|
heart formation
|
GO:0060914 |
13 |
0.048
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
57 |
0.047
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.047
|
Human |
|
|
radial glial cell differentiation
|
GO:0060019 |
2 |
0.046
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.045
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.045
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
3 |
0.045
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
48 |
0.044
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.044
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
45 |
0.043
|
|
|
|
formation of anatomical boundary
|
GO:0048859 |
14 |
0.043
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
80 |
0.043
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.043
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
9 |
0.042
|
|
|
|
larval development
|
GO:0002164 |
2 |
0.042
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
2 |
0.042
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
22 |
0.042
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
68 |
0.042
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
8 |
0.041
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
1 |
0.041
|
|
|
|
chemotaxis
|
GO:0006935 |
104 |
0.041
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
16 |
0.040
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.040
|
|
|
|
negative regulation of collateral sprouting of intact axon in response to injury
|
GO:0048685 |
2 |
0.040
|
|
|
|
dorsal aorta development
|
GO:0035907 |
4 |
0.040
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
17 |
0.039
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
48 |
0.038
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
2 |
0.038
|
|
|
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
20 |
0.038
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
0 |
0.038
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.038
|
|
|
|
posterior lateral line system development
|
GO:0048915 |
46 |
0.037
|
|
|
|
positive regulation of rac protein signal transduction
|
GO:0035022 |
1 |
0.037
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
6 |
0.037
|
|
|
|
epithelial tube formation
|
GO:0072175 |
19 |
0.037
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
50 |
0.037
|
Human |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
42 |
0.036
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
15 |
0.036
|
|
|
|
cell activation
|
GO:0001775 |
16 |
0.036
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
87 |
0.036
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
2 |
0.036
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
58 |
0.036
|
|
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.036
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
2 |
0.035
|
|
|
|
mesodermal cell fate specification
|
GO:0007501 |
12 |
0.035
|
|
|
|
angioblast cell migration
|
GO:0035476 |
9 |
0.035
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.035
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
6 |
0.034
|
|
|
|
cell migration to the midline involved in heart development
|
GO:0003318 |
12 |
0.034
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
38 |
0.034
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.034
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
35 |
0.033
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
53 |
0.033
|
|
|
|
optic placode formation involved in camera type eye formation
|
GO:0046619 |
3 |
0.033
|
|
|
|
single organism reproductive process
|
GO:0044702 |
40 |
0.033
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
1 |
0.033
|
|
|
|
neuron projection development
|
GO:0031175 |
180 |
0.033
|
|
|
|
single organism transport
|
GO:0044765 |
206 |
0.033
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.033
|
|
|
|
positive regulation of histone deacetylation
|
GO:0031065 |
1 |
0.033
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
69 |
0.033
|
|
|
|
pigmentation
|
GO:0043473 |
85 |
0.032
|
|
|
|
compound eye development
|
GO:0048749 |
2 |
0.032
|
Fly |
|
|
phagocytosis
|
GO:0006909 |
3 |
0.032
|
|
|
|
stem cell division
|
GO:0017145 |
1 |
0.032
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
63 |
0.031
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
21 |
0.031
|
|
|
|
wnt signaling pathway involved in somitogenesis
|
GO:0090244 |
2 |
0.031
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
55 |
0.031
|
|
|
|
tube closure
|
GO:0060606 |
1 |
0.030
|
|
|
|
regulation of collateral sprouting of intact axon in response to injury
|
GO:0048683 |
2 |
0.030
|
|
|
|
multi organism process
|
GO:0051704 |
134 |
0.030
|
Fly |
|
|
cell maturation
|
GO:0048469 |
23 |
0.030
|
|
|
|
response to wounding
|
GO:0009611 |
116 |
0.029
|
|
|
|
forebrain anterior posterior pattern specification
|
GO:0021797 |
3 |
0.029
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
68 |
0.029
|
Human |
|
|
axon guidance
|
GO:0007411 |
86 |
0.029
|
|
|
|
forebrain regionalization
|
GO:0021871 |
4 |
0.029
|
|
|
|
muscle tissue development
|
GO:0060537 |
110 |
0.029
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.029
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.028
|
|
|
|
cell migration in hindbrain
|
GO:0021535 |
7 |
0.028
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
13 |
0.028
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
7 |
0.028
|
|
|
|
ventricular cardiac muscle tissue development
|
GO:0003229 |
3 |
0.028
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
40 |
0.028
|
|
|
|
heart valve development
|
GO:0003170 |
14 |
0.027
|
|
|
|
mesoderm formation
|
GO:0001707 |
43 |
0.027
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
20 |
0.027
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.027
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
146 |
0.027
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.027
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
29 |
0.027
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.027
|
|
|
|
protein deacetylation
|
GO:0006476 |
3 |
0.027
|
|
|
|
axon development
|
GO:0061564 |
166 |
0.027
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
62 |
0.026
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
30 |
0.026
|
|
|
|
inner ear development
|
GO:0048839 |
126 |
0.026
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
3 |
0.026
|
|
|
|
angiogenesis
|
GO:0001525 |
158 |
0.026
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
5 |
0.026
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.026
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
1 |
0.025
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
13 |
0.025
|
|
|
|
establishment of localization
|
GO:0051234 |
244 |
0.025
|
|
|
|
lateral line system development
|
GO:0048925 |
76 |
0.025
|
|
|
|
reproductive process
|
GO:0022414 |
40 |
0.025
|
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.025
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
49 |
0.025
|
|
|
|
lateral line development
|
GO:0048882 |
66 |
0.025
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
24 |
0.025
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
110 |
0.025
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
97 |
0.025
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
179 |
0.025
|
|
|
|
regulation of histone deacetylation
|
GO:0031063 |
2 |
0.025
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
57 |
0.025
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
14 |
0.024
|
|
|
|
hypothalamus cell differentiation
|
GO:0021979 |
4 |
0.024
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
29 |
0.024
|
|
|
|
regulation of locomotion
|
GO:0040012 |
55 |
0.023
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
1 |
0.023
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
5 |
0.023
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
3 |
0.023
|
|
|
|
muscle cell development
|
GO:0055001 |
115 |
0.023
|
|
|
|
response to chemical
|
GO:0042221 |
320 |
0.023
|
Human |
|
|
kidney epithelium development
|
GO:0072073 |
23 |
0.023
|
|
|
|
positive regulation of embryonic development
|
GO:0040019 |
3 |
0.023
|
|
|
|
connective tissue development
|
GO:0061448 |
99 |
0.022
|
|
|
|
female gonad development
|
GO:0008585 |
4 |
0.022
|
|
|
|
regulation of collateral sprouting
|
GO:0048670 |
7 |
0.022
|
|
|
|
protein acetylation
|
GO:0006473 |
2 |
0.022
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
47 |
0.022
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
1 |
0.022
|
|
|
|
retinoic acid metabolic process
|
GO:0042573 |
9 |
0.022
|
|
|
|
intracellular transport
|
GO:0046907 |
32 |
0.022
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.022
|
|
|
|
dorsal aorta morphogenesis
|
GO:0035912 |
3 |
0.022
|
|
|
|
nephron tubule epithelial cell differentiation
|
GO:0072160 |
1 |
0.022
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
1 |
0.022
|
|
|
|
axonal fasciculation
|
GO:0007413 |
11 |
0.022
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
1 |
0.022
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
1 |
0.022
|
|
|
|
ventricular cardiac muscle tissue morphogenesis
|
GO:0055010 |
2 |
0.021
|
|
|
|
organic substance transport
|
GO:0071702 |
58 |
0.021
|
|
|
|
olfactory placode formation
|
GO:0030910 |
1 |
0.021
|
|
|
|
spinal cord radial glial cell differentiation
|
GO:0021531 |
2 |
0.021
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.021
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
3 |
0.021
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
4 |
0.021
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
3 |
0.021
|
|
|
|
neural crest cell development
|
GO:0014032 |
62 |
0.021
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
1 |
0.021
|
|
|
|
negative regulation of stem cell differentiation
|
GO:2000737 |
2 |
0.021
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
2 |
0.020
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.020
|
|
|
|
somite specification
|
GO:0001757 |
12 |
0.020
|
|
|
|
endothelial cell migration
|
GO:0043542 |
19 |
0.020
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
2 |
0.020
|
|
|
|
cell cell signaling
|
GO:0007267 |
52 |
0.020
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
2 |
0.020
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
52 |
0.020
|
|
|
|
cardioblast migration to the midline involved in heart field formation
|
GO:0060975 |
7 |
0.020
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
20 |
0.020
|
|
|
|
negative regulation of signal transduction by p53 class mediator
|
GO:1901797 |
8 |
0.020
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
1 |
0.020
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
20 |
0.020
|
|
|
|
behavior
|
GO:0007610 |
74 |
0.020
|
Fly |
|
|
kidney development
|
GO:0001822 |
92 |
0.020
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
1 |
0.019
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
2 |
0.019
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
54 |
0.019
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.019
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
9 |
0.019
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
7 |
0.019
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
11 |
0.019
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
1 |
0.019
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
2 |
0.019
|
|
|
|
regulation of gastrulation
|
GO:0010470 |
24 |
0.019
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
2 |
0.019
|
|
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
3 |
0.019
|
|
|
|
response to organic substance
|
GO:0010033 |
153 |
0.018
|
Human |
|
|
regulation of skeletal muscle tissue development
|
GO:0048641 |
4 |
0.018
|
|
|
|
posterior lateral line development
|
GO:0048916 |
38 |
0.018
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.018
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
55 |
0.018
|
|
|
|
endothelial cell fate commitment
|
GO:0060839 |
3 |
0.018
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
23 |
0.018
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
12 |
0.018
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
4 |
0.018
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
20 |
0.018
|
|
|
|
skin morphogenesis
|
GO:0043589 |
7 |
0.018
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
4 |
0.018
|
|
|
|
sex determination
|
GO:0007530 |
1 |
0.018
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
39 |
0.018
|
|
|
|
homeostatic process
|
GO:0042592 |
142 |
0.018
|
|
|
|
cardioblast differentiation
|
GO:0010002 |
9 |
0.018
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
2 |
0.018
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
42 |
0.018
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
2 |
0.018
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
25 |
0.018
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
30 |
0.017
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
68 |
0.017
|
|
|
|
nephron epithelium development
|
GO:0072009 |
16 |
0.017
|
|
|
|
b cell activation
|
GO:0042113 |
2 |
0.017
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
3 |
0.017
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
60 |
0.017
|
|
|
|
adult behavior
|
GO:0030534 |
2 |
0.017
|
|
|
|
regulation of cell motility
|
GO:2000145 |
46 |
0.017
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
3 |
0.017
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.017
|
|
|
|
sensory system development
|
GO:0048880 |
76 |
0.017
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
2 |
0.017
|
|
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.017
|
|
|
|
gland development
|
GO:0048732 |
143 |
0.017
|
Human |
|
|
posterior lateral line neuromast primordium migration
|
GO:0048920 |
12 |
0.017
|
|