IMP
Process View
regulation of transcription from rna polymerase ii promoter in response to oxidative stress
Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
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Click on a gene's description to view its network relationships with genes known to be involved in "regulation of transcription from rna polymerase ii promoter in response to oxidative stress"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| EPAS1 | endothelial PAS domain protein 1 | 0.985 | Human Mouse | |
| TRIB3 | tribbles homolog 3 (Drosophila) | 0.980 | ||
| EGLN1 | egl nine homolog 1 (C. elegans) | 0.924 | ||
| VHL | von Hippel-Lindau tumor suppressor | 0.728 | ||
| EGLN3 | egl nine homolog 3 (C. elegans) | 0.678 | ||
| KAT2B | K(lysine) acetyltransferase 2B | 0.621 | ||
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.557 | ||
| AHR | aryl hydrocarbon receptor | 0.536 | ||
| SP1 | Sp1 transcription factor | 0.534 | ||
| SMAD3 | SMAD family member 3 | 0.473 | ||
| ARNT | aryl hydrocarbon receptor nuclear translocator | 0.396 | ||
| PPARA | peroxisome proliferator-activated receptor alpha | 0.352 | ||
| TTR | transthyretin | 0.233 | ||
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.227 | ||
| EP300 | E1A binding protein p300 | 0.151 | ||
| DDIT3 | DNA-damage-inducible transcript 3 | 0.116 | ||
| CLOCK | clock homolog (mouse) | 0.107 | ||
| NCOR2 | nuclear receptor corepressor 2 | 0.106 | ||
| MAFG | v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) | 0.078 | ||
| JUN | jun proto-oncogene | 0.055 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.054 | ||
| BTRC | beta-transducin repeat containing | 0.046 | ||
| SSX4 | synovial sarcoma, X breakpoint 4 | 0.044 | ||
| CREBBP | CREB binding protein | 0.044 | ||
| POLR2C | polymerase (RNA) II (DNA directed) polypeptide C, 33kDa | 0.039 | ||
| NCOA2 | nuclear receptor coactivator 2 | 0.034 | ||
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 | 0.031 | ||
| CREB1 | cAMP responsive element binding protein 1 | 0.028 | ||
| ESR1 | estrogen receptor 1 | 0.024 | ||
| CUL2 | cullin 2 | 0.021 | ||
| MYST3 | MYST histone acetyltransferase (monocytic leukemia) 3 | 0.018 | ||
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.018 | ||
| KEAP1 | kelch-like ECH-associated protein 1 | 0.017 | ||
| NCOA6 | nuclear receptor coactivator 6 | 0.017 | ||
| NAMPT | nicotinamide phosphoribosyltransferase | 0.016 | ||
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor | 0.015 | ||
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like | 0.014 | Human | |
| ATF3 | activating transcription factor 3 | 0.010 |