IMP
Process View
aflatoxin catabolic process
The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "aflatoxin catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Gstm1 | glutathione S-transferase, mu 1 | 0.090 | ||
| Hsd3b7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 0.089 | ||
| Ces1d | carboxylesterase 1D | 0.037 | ||
| Gstt1 | glutathione S-transferase, theta 1 | 0.032 | ||
| Cbr1 | carbonyl reductase 1 | 0.017 | ||
| Gsto1 | glutathione S-transferase omega 1 | 0.016 | ||
| Pgls | 6-phosphogluconolactonase | 0.014 | ||
| Tmem205 | transmembrane protein 205 | 0.011 |