IMP

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Rattus norvegicus

0 genes annotated in rat

primary ciliary dyskinesia

DOID:9562

An autosomal recessive genetic disease that causes a defect in the action of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "primary ciliary dyskinesia" (in gray)

Name	Description	Probability	Func Analog Organism
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.606
Adam5	a disintegrin and metallopeptidase domain 5	0.317
Dnah11	dynein, axonemal, heavy chain 11	0.280
MGC94915	similar to hypothetical protein	0.221
Acaa1b	acetyl-Coenzyme A acyltransferase 1B	0.172
Kif27	kinesin family member 27	0.168
Dnahc6	dynein, axonemal, heavy chain 6	0.138
Tekt4	tektin 4	0.128
Dnah1	dynein, axonemal, heavy chain 1	0.126
Lrrc50	leucine rich repeat containing 50	0.112	Human
LOC500227	hypothetical gene supported by BC079424	0.098
LOC360479	similar to hypothetical protein	0.089
LOC100359800	rCG64478-like	0.086
Tekt1	tektin 1	0.084
Dynlrb2	dynein light chain roadblock-type 2	0.081
RGD1565611	RGD1565611	0.062
Kif1c	kinesin family member 1C	0.060
Wdr38	WD repeat domain 38	0.050
Tmem216	transmembrane protein 216	0.048
RGD1306233	similar to hypothetical protein MGC29761	0.044
Irs3	insulin receptor substrate 3	0.043
Olr1699	olfactory receptor 1699	0.039
Dnah2	dynein, axonemal, heavy chain 2	0.038
Foxj1	forkhead box J1	0.038
RGD1560244	similar to hypothetical protein FLJ34512	0.037
St3gal3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	0.034
Znf76	zinc finger protein 76 (expressed in testis)	0.030
Gnal	guanine nucleotide binding protein, alpha stimulating, olfactory type	0.029
Enah	enabled homolog (Drosophila)	0.026
Olr1606	olfactory receptor 1606	0.024
Tsga10	testis specific 10	0.024
Dnai1	dynein, axonemal, intermediate chain 1	0.024	Human
Cdh4	cadherin 4	0.023
Grpcb	glutamine/glutamic acid-rich protein A	0.022
Fam183b	family with sequence similarity 183, member B	0.020
Olr1347	olfactory receptor 1347	0.020
Ager	advanced glycosylation end product-specific receptor	0.018
Ccdc153	coiled-coil domain containing 153	0.018
RGD1310262	hypothetical LOC304650	0.018
Myo1a	myosin IA	0.016
RGD1562525	similar to cell surface receptor FDFACT	0.015
Fabp9	fatty acid binding protein 9, testis	0.015
Iiig9	IIIG9 protein	0.015
Acan	aggrecan	0.014
LOC100359753	hypothetical protein LOC100359753	0.014
RGD1565493	similar to DKFZP434I092 protein	0.014
Pou5f2	POU domain class 5, transcription factor 2	0.013
Akap14	A kinase (PRKA) anchor protein 14	0.013
Myl3	myosin, light chain 3, alkali; ventricular, skeletal, slow	0.013
Flg	filaggrin	0.012
Ttc25	tetratricopeptide repeat domain 25	0.012
Mfhas1	malignant fibrous histiocytoma amplified sequence 1	0.012
Gsta2	glutathione S-transferase A2	0.012
Ccdc19	coiled-coil domain containing 19	0.012
Lrrc46	leucine rich repeat containing 46	0.011
Morn1	MORN repeat containing 1	0.011
Dnajb13	DnaJ (Hsp40) related, subfamily B, member 13	0.011
Rsb66	Rsb-66 protein	0.011
Prss2	protease, serine, 2	0.011
Plunc	palate, lung, and nasal epithelium associated	0.011
Dnah7	dynein, axonemal, heavy polypeptide 7	0.011
RGD1562658	similar to RIKEN cDNA 1700009P17	0.011
LOC502684	hypothetical protein LOC502684	0.011
LOC494499	LOC494499 protein	0.010
Dnah5	dynein, axonemal, heavy chain 5	0.010	Human