IMP
Process View
leukocyte tethering or rolling
Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection).
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "leukocyte tethering or rolling"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Olr1701 | olfactory receptor 1701 | 0.157 | ||
| Hnrnpab | heterogeneous nuclear ribonucleoprotein A/B | 0.129 | ||
| Atp1b3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.067 | ||
| Cd48 | Cd48 molecule | 0.055 | ||
| Olr1469 | olfactory receptor Olr1469 | 0.038 | ||
| Selp | selectin P | 0.036 | Mouse | |
| Vim | vimentin | 0.034 | ||
| Anxa4 | annexin A4 | 0.032 | ||
| Sele | selectin E | 0.030 | Human | |
| Ahnak | AHNAK nucleoprotein | 0.027 | ||
| Csf3 | colony stimulating factor 3 (granulocyte) | 0.025 | ||
| Cyp11a1 | cytochrome P450, family 11, subfamily a, polypeptide 1 | 0.025 | ||
| Cmtm6 | CKLF-like MARVEL transmembrane domain containing 6 | 0.023 | ||
| Obp3 | alpha-2u globulin PGCL4 | 0.023 | ||
| Sept2 | septin 2 | 0.021 | ||
| Plscr2 | phospholipid scramblase 2 | 0.020 | ||
| Rbms1 | RNA binding motif, single stranded interacting protein 1 | 0.020 | ||
| Adam17 | ADAM metallopeptidase domain 17 | 0.019 | ||
| Cyp4a8 | cytochrome P450, family 4, subfamily a, polypeptide 8 | 0.019 | ||
| Fermt2 | fermitin family homolog 2 (Drosophila) | 0.018 | ||
| Capn2 | calpain 2 | 0.018 | ||
| Mdfic | MyoD family inhibitor domain containing | 0.017 | ||
| Ctnna1 | catenin (cadherin associated protein), alpha 1 | 0.017 | ||
| Plod1 | procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 | 0.017 | ||
| Tas2r105 | taste receptor, type 2, member 105 | 0.016 | ||
| Mmp7 | matrix metallopeptidase 7 | 0.015 | ||
| Reg3g | regenerating islet-derived 3 gamma | 0.015 | ||
| Anxa5 | annexin A5 | 0.015 | ||
| Mgea5 | meningioma expressed antigen 5 (hyaluronidase) | 0.014 | ||
| Plat | plasminogen activator, tissue | 0.014 | ||
| Ddx21 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 | 0.014 | ||
| Btg1 | B-cell translocation gene 1, anti-proliferative | 0.014 | ||
| Rrad | Ras-related associated with diabetes | 0.014 | ||
| Grk4 | G protein-coupled receptor kinase 4 | 0.013 | ||
| Marcks | myristoylated alanine rich protein kinase C substrate | 0.012 | ||
| Csf2rb | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.012 | ||
| Cd151 | CD151 molecule (Raph blood group) | 0.012 | ||
| Clec2d | C-type lectin domain family 2, member d | 0.012 | ||
| Ptn | pleiotrophin | 0.011 | ||
| Olr1362 | olfactory receptor 1362 | 0.011 | ||
| Tmod3 | tropomodulin 3 | 0.011 | ||
| Rcn2 | reticulocalbin 2, EF-hand calcium binding domain | 0.011 | ||
| F2r | coagulation factor II (thrombin) receptor | 0.011 | ||
| Gulp1 | GULP, engulfment adaptor PTB domain containing 1 | 0.011 | ||
| Lipogenin | Lipogenin | 0.011 | ||
| Crybb3 | crystallin, beta B3 | 0.010 | ||
| Prss23 | protease, serine, 23 | 0.010 | ||
| Emp1 | epithelial membrane protein 1 | 0.010 |