The network for 'regulation of histone h3 k9 methylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of histone h3 k9 methylation

Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.

Drosophila melanogaster
Name Description Probability Func Analog Organism
His1:CG33825 CG33825 gene product from transcript CG33825-RA 0.907
His1:CG33840 CG33840 gene product from transcript CG33840-RA 0.851
His1:CG33834 CG33834 gene product from transcript CG33834-RA 0.851
His1:CG33828 CG33828 gene product from transcript CG33828-RA 0.700
His1:CG33822 CG33822 gene product from transcript CG33822-RA 0.684
His1:CG33819 CG33819 gene product from transcript CG33819-RA 0.672
His1:CG33849 CG33849 gene product from transcript CG33849-RA 0.672
His1:CG33861 CG33861 gene product from transcript CG33861-RA 0.656
His1:CG33858 CG33858 gene product from transcript CG33858-RA 0.656
His1:CG33855 CG33855 gene product from transcript CG33855-RA 0.656
His1:CG33864 CG33864 gene product from transcript CG33864-RA 0.648
His1:CG33831 CG33831 gene product from transcript CG33831-RA 0.624
His1:CG33816 CG33816 gene product from transcript CG33816-RA 0.612
His1:CG33843 CG33843 gene product from transcript CG33843-RA 0.612
His1:CG33813 CG33813 gene product from transcript CG33813-RA 0.612
His1:CG33846 CG33846 gene product from transcript CG33846-RA 0.612
His1:CG33801 CG33801 gene product from transcript CG33801-RA 0.603
His1:CG33804 CG33804 gene product from transcript CG33804-RA 0.600
His1:CG33837 CG33837 gene product from transcript CG33837-RA 0.597
His1:CG33852 CG33852 gene product from transcript CG33852-RA 0.597
His1:CG33807 CG33807 gene product from transcript CG33807-RA 0.579
His1:CG33810 CG33810 gene product from transcript CG33810-RA 0.513
His1:CG31617 CG31617 gene product from transcript CG31617-RA 0.231
IM23 Immune induced molecule 23 0.224
CG33680 CG33680 gene product from transcript CG33680-RA 0.135
woc without children 0.115
ro rough 0.105
Tom Twin of m4 0.076
pzg putzig 0.052
CG17564 CG17564 gene product from transcript CG17564-RB 0.051
CG34116 CG34116 gene product from transcript CG34116-RA 0.027
CG13581 CG13581 gene product from transcript CG13581-RA 0.026
cg combgap 0.026
sens senseless 0.024
RpL37b Ribosomal protein L37b 0.020
CG3287 CG3287 gene product from transcript CG3287-RB 0.019
CG14183 CG14183 gene product from transcript CG14183-RA 0.016
His3:CG31613 CG31613 gene product from transcript CG31613-RA 0.016
beta4GalT7 beta-4-galactosyltransferase 7 0.014
CG17744 CG17744 gene product from transcript CG17744-RA 0.013
His2Av Histone H2A variant 0.013
CSN6 COP9 complex homolog subunit 6 0.013
CG2662 CG2662 gene product from transcript CG2662-RA 0.012
bbx bobby sox 0.012
atms antimeros 0.012
CG18619 CG18619 gene product from transcript CG18619-RD 0.012
Deaf1 Deformed epidermal autoregulatory factor-1 0.011
CG4726 CG4726 gene product from transcript CG4726-RA 0.011
Lar Leukocyte-antigen-related-like 0.011
Ack CG14992 gene product from transcript CG14992-RA 0.011
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
gata1a GATA binding protein 1a 0.585
dnmt7 DNA (cytosine-5-)-methyltransferase 7 0.440
smc2 structural maintenance of chromosomes 2 0.267
pds5b PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) 0.227
dnmt1 DNA (cytosine-5-)-methyltransferase 1 0.220
dnmt5 DNA (cytosine-5-)-methyltransferase 5 0.207
dnmt3 DNA (cytosine-5-)-methyltransferase 3 0.187
runx1 runt-related transcription factor 1 0.178
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.173
rif1 RAP1 interacting factor homolog (yeast) 0.165
ahctf1 AT hook containing transcription factor 1 0.154
pwp2h PWP2 periodic tryptophan protein homolog (yeast) 0.120
pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.104
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.101
pcna proliferating cell nuclear antigen 0.098
cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) 0.079
chtf18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 0.072
LOC567638 hypothetical LOC567638 0.071
zgc:158643 zgc:158643 0.071
hells helicase, lymphoid-specific 0.070
msh2 mutS homolog 2 (E. coli) 0.065
smc3 structural maintenance of chromosomes 3 0.061
dnmt6 DNA (cytosine-5-)-methyltransferase 6 0.060
lmnb1 lamin B1 0.056
msh6 mutS homolog 6 (E. coli) 0.054
sass6 spindle assembly 6 homolog (C. elegans) 0.052
cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.050
chaf1b chromatin assembly factor 1, subunit B 0.049
pola1 polymerase (DNA directed), alpha 1 0.045
atad5a ATPase family, AAA domain containing 5a 0.039
sephs1 selenophosphate synthetase 1 0.038
usp1 ubiquitin specific protease 1 0.036
ikzf1 IKAROS family zinc finger 1 (Ikaros) 0.035
ezh2 enhancer of zeste homolog 2 (Drosophila) 0.034
ssrp1a structure specific recognition protein 1a 0.033
dnmt8 DNA (cytosine-5-)-methyltransferase 8 0.032
setdb1a SET domain, bifurcated 1a 0.030
ncaph non-SMC condensin I complex, subunit H 0.028
dhfr dihydrofolate reductase 0.028
chek2 CHK2 checkpoint homolog (S. pombe) 0.026
rx1 retinal homeobox gene 1 0.026
cbx1a chromobox homolog 1a (HP1 beta homolog Drosophila) 0.025
ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.024
palb2 partner and localizer of BRCA2 0.024
suv39h1b suppressor of variegation 3-9 homolog 1b 0.023
rab11fip4a RAB11 family interacting protein 4 (class II) a 0.022
plk4 polo-like kinase 4 (Drosophila) 0.022
zgc:110113 zgc:110113 0.022
fabp10a fatty acid binding protein 10a, liver basic 0.021
kif15 kinesin family member 15 0.020
stil TAL1 (SCL) interrupting locus 0.020
mpx myeloid-specific peroxidase 0.020
rb1 retinoblastoma 1 0.019
emx3 empty spiracles homeobox 3 0.019
cdc16 cell division cycle 16 homolog (S. cerevisiae) 0.018
zfp36l1a zinc finger protein 36, C3H type-like 1a 0.018
crb2a crumbs homolog 2a 0.018
cabin1 calcineurin binding protein 1 0.018
her2 hairy-related 2 0.017
hirip3 HIRA interacting protein 3 0.017
smc4 structural maintenance of chromosomes 4 0.017
cbx2 chromobox homolog 2 (Drosophila Pc class) 0.017
mybl2 myeloblastosis oncogene-like 2 0.017
fgfrl1a fibroblast growth factor receptor-like 1a 0.017
marcksb myristoylated alanine rich protein kinase C substrate b 0.016
ncapg2 non-SMC condensin II complex, subunit G2 0.016
mre11a meiotic recombination 11 homolog A (S. cerevisiae) 0.016
pxn paxillin 0.015
fbxo9 F-box protein 9 0.015
efna2 ephrin A2 0.014
fgfr1b fibroblast growth factor receptor 1b 0.014
apex1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.014
aurka aurora kinase A 0.013
pnn pinin, desmosome associated protein 0.013
brip1 BRCA1 interacting protein C-terminal helicase 1 0.013
nasp nuclear autoantigenic sperm protein (histone-binding) 0.013
paxip1 PAX interacting (with transcription-activation domain) protein 1 0.013
mcm7 MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) 0.013
setd6 SET domain containing 6 0.012
vsx2 visual system homeobox 2 0.012
gdf11 growth differentiation factor 11 0.012
skiv2l2 superkiller viralicidic activity 2-like 2 0.012
dntt deoxynucleotidyltransferase, terminal 0.012
ncapd2 non-SMC condensin I complex, subunit D2 0.012
mcm6 MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae) 0.012
rx2 retinal homeobox gene 2 0.012
krcp kelch repeat-containing protein 0.012
cbx5 chromobox homolog 5 (HP1 alpha homolog, Drosophila) 0.012
anp32a acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.011
aggf1 angiogenic factor with G patch and FHA domains 1 0.011
nkx2.1a NK2 homeobox 1a 0.011
adnp2b ADNP homeobox 2b 0.011
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.011
pbp phosphatidylethanolamine binding protein 0.011
vgll4l vestigial like 4 like 0.011
slbp stem-loop binding protein 0.011
alp alkaline phosphatase 0.011
mcm3 MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.011
col14a1 collagen, type XIV, alpha 1 0.011
LOC100151531 zinc finger protein Gfi-1b-like 0.011
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
CBX5 chromobox homolog 5 0.489
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.172
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.136
LIN9 lin-9 homolog (C. elegans) 0.075
HIST1H3B histone cluster 1, H3b 0.070
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.046
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.029
MBD1 methyl-CpG binding domain protein 1 0.027
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.016
RB1 retinoblastoma 1 0.016
RBBP5 retinoblastoma binding protein 5 0.015
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.014
SUZ12 suppressor of zeste 12 homolog (Drosophila) 0.013
H2AFX H2A histone family, member X 0.013
TSC22D1 TSC22 domain family, member 1 0.011
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.999
Dnmt3a DNA methyltransferase 3A 0.950
Mtf2 metal response element binding transcription factor 2 0.921
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.899
Trim24 tripartite motif-containing 24 0.884
Jarid2 jumonji, AT rich interactive domain 2 0.597
Emx2 empty spiracles homolog 2 (Drosophila) 0.542
Trim28 tripartite motif-containing 28 0.518
Crebbp CREB binding protein 0.469
Lef1 lymphoid enhancer binding factor 1 0.332
Rbbp4 retinoblastoma binding protein 4 0.307
Gata3 GATA binding protein 3 0.303
Brca2 breast cancer 2 0.262
Esr1 estrogen receptor 1 (alpha) 0.254
Hdac1 histone deacetylase 1 0.239
Setx senataxin 0.238
Ar androgen receptor 0.222
Msx1 homeobox, msh-like 1 0.221
Akap9 A kinase (PRKA) anchor protein (yotiao) 9 0.192
Aebp2 AE binding protein 2 0.184
Ncoa6 nuclear receptor coactivator 6 0.170
Gata1 GATA binding protein 1 0.158
Zfp292 zinc finger protein 292 0.141
Trp63 transformation related protein 63 0.129
Hells helicase, lymphoid specific 0.119
Bptf bromodomain PHD finger transcription factor 0.111
Stk38 serine/threonine kinase 38 0.108
Rb1 retinoblastoma 1 0.108
Fgfr2 fibroblast growth factor receptor 2 0.101
Mll1 myeloid/lymphoid or mixed-lineage leukemia 1 0.101
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.096
Mbtd1 mbt domain containing 1 0.082
Cbx5 chromobox homolog 5 (Drosophila HP1a) 0.074
Prkdc protein kinase, DNA activated, catalytic polypeptide 0.072
Kdm1a lysine (K)-specific demethylase 1A 0.070
Lepr leptin receptor 0.065
Hand1 heart and neural crest derivatives expressed transcript 1 0.060
Hist1h3g histone cluster 1, H3g 0.058
Atm ataxia telangiectasia mutated homolog (human) 0.057
Chaf1a chromatin assembly factor 1, subunit A (p150) 0.057
Med13l mediator complex subunit 13-like 0.056
Fgf10 fibroblast growth factor 10 0.055
Ezh1 enhancer of zeste homolog 1 (Drosophila) 0.053
Cbx1 chromobox homolog 1 (Drosophila HP1 beta) 0.050
Zeb1 zinc finger E-box binding homeobox 1 0.049
Arid2 AT rich interactive domain 2 (ARID, RFX-like) 0.049
Kiss1 KiSS-1 metastasis-suppressor 0.049
Trim33 tripartite motif-containing 33 0.049
Ep300 E1A binding protein p300 0.045
Brd4 bromodomain containing 4 0.045
Wnt9b wingless-type MMTV integration site 9B 0.042
Paxip1 PAX interacting (with transcription-activation domain) protein 1 0.042
Gsk3b glycogen synthase kinase 3 beta 0.041
Ankhd1 ankyrin repeat and KH domain containing 1 0.035
Prlr prolactin receptor 0.035
Sp1 trans-acting transcription factor 1 0.034
Eed embryonic ectoderm development 0.033
Brca1 breast cancer 1 0.033
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.032
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.032
Rag1 recombination activating gene 1 0.032
Chd7 chromodomain helicase DNA binding protein 7 0.031
Dnmt3l DNA (cytosine-5-)-methyltransferase 3-like 0.030
Arid1a AT rich interactive domain 1A (SWI-like) 0.030
Shh sonic hedgehog 0.030
Kdm5a lysine (K)-specific demethylase 5A 0.030
Sin3a transcriptional regulator, SIN3A (yeast) 0.030
Rxra retinoid X receptor alpha 0.029
Csnk2a1 casein kinase 2, alpha 1 polypeptide 0.029
Nipbl Nipped-B homolog (Drosophila) 0.028
Ncoa1 nuclear receptor coactivator 1 0.028
Tnrc6c trinucleotide repeat containing 6C 0.028
Foxn1 forkhead box N1 0.028
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.026
Clk1 CDC-like kinase 1 0.025
Pou5f1 POU domain, class 5, transcription factor 1 0.025
Epc1 enhancer of polycomb homolog 1 (Drosophila) 0.025
Cramp1l Crm, cramped-like (Drosophila) 0.025
Gfi1b growth factor independent 1B 0.024
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.023
Ilf3 interleukin enhancer binding factor 3 0.023
Lhx1 LIM homeobox protein 1 0.023
Dmtf1 cyclin D binding myb-like transcription factor 1 0.022
Pparg peroxisome proliferator activated receptor gamma 0.021
Zfp654 zinc finger protein 654 0.020
Drd2 dopamine receptor D2 0.020
Eya1 eyes absent 1 homolog (Drosophila) 0.020
Lmx1a LIM homeobox transcription factor 1 alpha 0.019
Morc3 microrchidia 3 0.019
Msx2 homeobox, msh-like 2 0.019
Cry1 cryptochrome 1 (photolyase-like) 0.019
Trrap transformation/transcription domain-associated protein 0.019
Srsf4 serine/arginine-rich splicing factor 4 0.019
Casp2 caspase 2 0.019
Chd2 chromodomain helicase DNA binding protein 2 0.019
Hnrnpul1 heterogeneous nuclear ribonucleoprotein U-like 1 0.018
Ptch1 patched homolog 1 0.018
Dhx15 DEAH (Asp-Glu-Ala-His) box polypeptide 15 0.018
Nanog Nanog homeobox 0.018
Trp53 transformation related protein 53 0.018
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Safb scaffold attachment factor B 0.038
Phf12 PHD finger protein 12 0.029
Gtf2i general transcription factor II I 0.019
Pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.013
Ctcf CCCTC-binding factor (zinc finger protein) 0.012
Rfwd3 ring finger and WD repeat domain 3 0.011
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism