IMP
Process View
The network for 'semaphorin plexin signaling pathway involved in outflow tract morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
semaphorin plexin signaling pathway involved in outflow tract morphogenesis
A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand that contributes to outflow tract morphogenesis.
| Name | Description | Probability | Func Analog Organism |
|---|
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Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Otx2 | orthodenticle homolog 2 (Drosophila) | 1.000 | |
| Pax6 | paired box gene 6 | 1.000 | |
| Shh | sonic hedgehog | 1.000 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.999 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.997 | |
| Pax3 | paired box gene 3 | 0.997 | |
| Neurod1 | neurogenic differentiation 1 | 0.995 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.994 | |
| Foxc2 | forkhead box C2 | 0.992 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.992 | |
| Msx1 | homeobox, msh-like 1 | 0.990 | |
| Fgf8 | fibroblast growth factor 8 | 0.987 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.984 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.965 | |
| Hoxa1 | homeobox A1 | 0.941 | |
| Neurod4 | neurogenic differentiation 4 | 0.935 | |
| Foxc1 | forkhead box C1 | 0.933 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.926 | |
| Gata4 | GATA binding protein 4 | 0.922 | |
| Gsc | goosecoid homeobox | 0.921 | |
| Neurog2 | neurogenin 2 | 0.919 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.917 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.903 | |
| Prrx1 | paired related homeobox 1 | 0.903 | |
| Onecut1 | one cut domain, family member 1 | 0.879 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.873 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.866 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.854 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.846 | |
| En1 | engrailed 1 | 0.838 | |
| Nhlh1 | nescient helix loop helix 1 | 0.835 | |
| Ptf1a | pancreas specific transcription factor, 1a | 0.786 | |
| Tbx1 | T-box 1 | 0.762 | |
| Lhx3 | LIM homeobox protein 3 | 0.743 | |
| Bmp4 | bone morphogenetic protein 4 | 0.735 | |
| Pdx1 | pancreatic and duodenal homeobox 1 | 0.730 | |
| Sox9 | SRY-box containing gene 9 | 0.722 | |
| Hoxd13 | homeobox D13 | 0.665 | |
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.665 | |
| Sox11 | SRY-box containing gene 11 | 0.654 | |
| Chrd | chordin | 0.644 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.627 | |
| Insm1 | insulinoma-associated 1 | 0.626 | |
| Msx2 | homeobox, msh-like 2 | 0.619 | |
| Mecom | MDS1 and EVI1 complex locus | 0.610 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.603 | |
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.600 | |
| Pou4f2 | POU domain, class 4, transcription factor 2 | 0.596 | |
| Foxg1 | forkhead box G1 | 0.595 | |
| Gpr50 | G-protein-coupled receptor 50 | 0.587 | |
| Prrx2 | paired related homeobox 2 | 0.578 | |
| Alx3 | aristaless-like homeobox 3 | 0.576 | |
| Neurog1 | neurogenin 1 | 0.575 | |
| Lhx9 | LIM homeobox protein 9 | 0.574 | |
| Six6 | sine oculis-related homeobox 6 homolog (Drosophila) | 0.566 | |
| Hoxa2 | homeobox A2 | 0.550 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.529 | |
| Dlx5 | distal-less homeobox 5 | 0.529 | |
| Smo | smoothened homolog (Drosophila) | 0.528 | |
| Hoxd3 | homeobox D3 | 0.528 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.528 | |
| Lhx5 | LIM homeobox protein 5 | 0.525 | |
| Mab21l2 | mab-21-like 2 (C. elegans) | 0.514 | |
| Dlx2 | distal-less homeobox 2 | 0.513 | |
| Six3 | sine oculis-related homeobox 3 homolog (Drosophila) | 0.508 | |
| Sox2 | SRY-box containing gene 2 | 0.507 | |
| Fgf15 | fibroblast growth factor 15 | 0.497 | |
| Pax2 | paired box gene 2 | 0.490 | |
| Neurog3 | neurogenin 3 | 0.444 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.426 | |
| Ednra | endothelin receptor type A | 0.412 | |
| Hoxb1 | homeobox B1 | 0.396 | |
| Efna2 | ephrin A2 | 0.384 | |
| Ebf3 | early B-cell factor 3 | 0.381 | |
| Pax9 | paired box gene 9 | 0.374 | |
| Nkx3-2 | NK3 homeobox 2 | 0.349 | |
| Tlx3 | T-cell leukemia, homeobox 3 | 0.347 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.346 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.341 | |
| Hoxd1 | homeobox D1 | 0.340 | |
| Ntf3 | neurotrophin 3 | 0.317 | |
| Gata1 | GATA binding protein 1 | 0.317 | |
| Myf5 | myogenic factor 5 | 0.311 | |
| Hba-x | hemoglobin X, alpha-like embryonic chain in Hba complex | 0.302 | |
| Dlx6 | distal-less homeobox 6 | 0.301 | |
| En2 | engrailed 2 | 0.300 | |
| Hmx1 | H6 homeobox 1 | 0.299 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.298 | |
| Foxd2 | forkhead box D2 | 0.294 | |
| Mesp1 | mesoderm posterior 1 | 0.291 | |
| Hoxc5 | homeobox C5 | 0.261 | |
| Pax1 | paired box gene 1 | 0.259 | |
| Arx | aristaless related homeobox | 0.253 | |
| Hoxa10 | homeobox A10 | 0.251 | |
| Nkx1-2 | NK1 transcription factor related, locus 2 (Drosophila) | 0.232 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.230 | |
| Dlx1 | distal-less homeobox 1 | 0.222 | |
| Shox2 | short stature homeobox 2 | 0.219 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.212 | |
| T | brachyury | 0.212 |