IMP
Process View
The network for 'renal tubular secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
renal tubular secretion
Secretion of substances from peritubular capillaries into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs.
| Name | Description | Probability | Func Analog Organism |
|---|
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| NCR2 | natural cytotoxicity triggering receptor 2 | 0.630 | |
| SLC28A1 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 | 0.627 | |
| SLC34A1 | solute carrier family 34 (sodium phosphate), member 1 | 0.553 | |
| PRODH2 | proline dehydrogenase (oxidase) 2 | 0.464 | |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter, GABA), member 13 | 0.335 | |
| SLC12A3 | solute carrier family 12 (sodium/chloride transporters), member 3 | 0.289 | |
| CST9L | cystatin 9-like | 0.271 | |
| SLC22A8 | solute carrier family 22 (organic anion transporter), member 8 | 0.185 | |
| SLC17A1 | solute carrier family 17 (sodium phosphate), member 1 | 0.144 | |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 | 0.133 | |
| CRYBB3 | crystallin, beta B3 | 0.106 | |
| PKLR | pyruvate kinase, liver and RBC | 0.088 | |
| GLYAT | glycine-N-acyltransferase | 0.077 | |
| SLC6A12 | solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 | 0.068 | |
| MASP2 | mannan-binding lectin serine peptidase 2 | 0.063 | |
| AIRE | autoimmune regulator | 0.063 | |
| CRYAA | crystallin, alpha A | 0.063 | |
| SLC17A3 | solute carrier family 17 (sodium phosphate), member 3 | 0.060 | |
| C8A | complement component 8, alpha polypeptide | 0.055 | |
| AGXT | alanine-glyoxylate aminotransferase | 0.055 | |
| CCIN | calicin | 0.051 | |
| SLC22A6 | solute carrier family 22 (organic anion transporter), member 6 | 0.050 | |
| TREH | trehalase (brush-border membrane glycoprotein) | 0.049 | |
| SHBG | sex hormone-binding globulin | 0.048 | |
| RTP3 | receptor (chemosensory) transporter protein 3 | 0.047 | |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) | 0.046 | |
| CCL1 | chemokine (C-C motif) ligand 1 | 0.044 | |
| FTCD | formiminotransferase cyclodeaminase | 0.044 | |
| RDH16 | retinol dehydrogenase 16 (all-trans) | 0.044 | |
| C8B | complement component 8, beta polypeptide | 0.044 | |
| DBH | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | 0.043 | |
| GBA3 | glucosidase, beta, acid 3 (cytosolic) | 0.041 | |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 | 0.040 | |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) | 0.040 | |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 | 0.039 | |
| HPX | hemopexin | 0.038 | |
| NR5A1 | nuclear receptor subfamily 5, group A, member 1 | 0.038 | |
| SERPINA10 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 | 0.037 | |
| UPB1 | ureidopropionase, beta | 0.035 | |
| C21orf62 | chromosome 21 open reading frame 62 | 0.035 | |
| GCGR | glucagon receptor | 0.035 | |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 | 0.035 | |
| CYP8B1 | cytochrome P450, family 8, subfamily B, polypeptide 1 | 0.035 | |
| FOXN1 | forkhead box N1 | 0.034 | |
| DPYS | dihydropyrimidinase | 0.032 | |
| BAAT | bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) | 0.031 | |
| HNF1B | HNF1 homeobox B | 0.031 | |
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.030 | |
| BTNL3 | butyrophilin-like 3 | 0.030 | |
| ALPI | alkaline phosphatase, intestinal | 0.029 | |
| HPD | 4-hydroxyphenylpyruvate dioxygenase | 0.029 | |
| GPR31 | G protein-coupled receptor 31 | 0.029 | |
| PROZ | protein Z, vitamin K-dependent plasma glycoprotein | 0.027 | |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) | 0.027 | |
| HABP2 | hyaluronan binding protein 2 | 0.026 | |
| FUT5 | fucosyltransferase 5 (alpha (1,3) fucosyltransferase) | 0.026 | |
| SYT11 | synaptotagmin XI | 0.025 | |
| DDC | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 0.025 | |
| CYP11B2 | cytochrome P450, family 11, subfamily B, polypeptide 2 | 0.025 | |
| DRD2 | dopamine receptor D2 | 0.025 | |
| XDH | xanthine dehydrogenase | 0.024 | |
| KCNJ1 | potassium inwardly-rectifying channel, subfamily J, member 1 | 0.024 | |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) | 0.024 | |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.024 | |
| LPA | lipoprotein, Lp(a) | 0.024 | |
| TEX13A | testis expressed 13A | 0.023 | |
| SPATA21 | spermatogenesis associated 21 | 0.023 | |
| ESRRB | estrogen-related receptor beta | 0.023 | |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | 0.023 | |
| TM4SF5 | transmembrane 4 L six family member 5 | 0.022 | |
| HOXC8 | homeobox C8 | 0.022 | |
| BPI | bactericidal/permeability-increasing protein | 0.022 | |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 | 0.022 | |
| VIL1 | villin 1 | 0.022 | |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | 0.022 | |
| XPNPEP2 | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound | 0.022 | |
| IFNA6 | interferon, alpha 6 | 0.022 | |
| C9 | complement component 9 | 0.022 | |
| CHRND | cholinergic receptor, nicotinic, delta | 0.022 | |
| RTDR1 | rhabdoid tumor deletion region gene 1 | 0.021 | |
| GUCA2B | guanylate cyclase activator 2B (uroguanylin) | 0.021 | |
| CLCNKB | chloride channel Kb | 0.021 | |
| SLC13A2 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 | 0.021 | |
| GGTLC1 | gamma-glutamyltransferase light chain 1 | 0.021 | |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) | 0.021 | |
| LASS2 | LAG1 homolog, ceramide synthase 2 | 0.021 | |
| AFM | afamin | 0.020 | |
| NR1I3 | nuclear receptor subfamily 1, group I, member 3 | 0.020 | |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | 0.020 | |
| HAO2 | hydroxyacid oxidase 2 (long chain) | 0.020 | |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 | 0.020 | |
| FETUB | fetuin B | 0.020 | |
| CPN2 | carboxypeptidase N, polypeptide 2 | 0.019 | |
| ABCB11 | ATP-binding cassette, sub-family B (MDR/TAP), member 11 | 0.019 | |
| G6PC | glucose-6-phosphatase, catalytic subunit | 0.019 | |
| NAT8B | N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) | 0.019 | |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.019 | |
| UNC93A | unc-93 homolog A (C. elegans) | 0.018 | |
| SLC22A2 | solute carrier family 22 (organic cation transporter), member 2 | 0.018 | |
| AQP7 | aquaporin 7 | 0.018 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Cyp2c54 | cytochrome P450, family 2, subfamily c, polypeptide 54 | 0.921 | |
| G6pc | glucose-6-phosphatase, catalytic | 0.906 | |
| Cyp4a14 | cytochrome P450, family 4, subfamily a, polypeptide 14 | 0.892 | |
| Cyp2c38 | cytochrome P450, family 2, subfamily c, polypeptide 38 | 0.862 | |
| Keg1 | kidney expressed gene 1 | 0.840 | |
| Alb | albumin | 0.839 | |
| Cyp3a11 | cytochrome P450, family 3, subfamily a, polypeptide 11 | 0.837 | |
| Akr1c6 | aldo-keto reductase family 1, member C6 | 0.777 | |
| Cyp2c29 | cytochrome P450, family 2, subfamily c, polypeptide 29 | 0.760 | |
| Ugt2b1 | UDP glucuronosyltransferase 2 family, polypeptide B1 | 0.755 | |
| Cps1 | carbamoyl-phosphate synthetase 1 | 0.741 | |
| Slc22a2 | solute carrier family 22 (organic cation transporter), member 2 | 0.674 | |
| Hsd3b2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 | 0.674 | |
| Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.654 | |
| Pigr | polymeric immunoglobulin receptor | 0.649 | |
| Cyp2a12 | cytochrome P450, family 2, subfamily a, polypeptide 12 | 0.623 | |
| Crp | C-reactive protein, pentraxin-related | 0.579 | |
| Cyp2c39 | cytochrome P450, family 2, subfamily c, polypeptide 39 | 0.538 | |
| Azgp1 | alpha-2-glycoprotein 1, zinc | 0.500 | |
| Cyp2b10 | cytochrome P450, family 2, subfamily b, polypeptide 10 | 0.482 | |
| Slc22a1 | solute carrier family 22 (organic cation transporter), member 1 | 0.479 | |
| Hpd | 4-hydroxyphenylpyruvic acid dioxygenase | 0.417 | |
| Cyp2b13 | cytochrome P450, family 2, subfamily b, polypeptide 13 | 0.401 | |
| Cml2 | camello-like 2 | 0.398 | |
| Cyp2c50 | cytochrome P450, family 2, subfamily c, polypeptide 50 | 0.397 | |
| Mup5 | major urinary protein 5 | 0.339 | |
| Cyp3a13 | cytochrome P450, family 3, subfamily a, polypeptide 13 | 0.326 | |
| Krtap6-1 | keratin associated protein 6-1 | 0.321 | |
| Cyp2b9 | cytochrome P450, family 2, subfamily b, polypeptide 9 | 0.300 | |
| Baat | bile acid-Coenzyme A: amino acid N-acyltransferase | 0.286 | |
| Hgd | homogentisate 1, 2-dioxygenase | 0.278 | |
| Inmt | indolethylamine N-methyltransferase | 0.274 | |
| Cyp2d9 | cytochrome P450, family 2, subfamily d, polypeptide 9 | 0.271 | |
| Cyp4b1 | cytochrome P450, family 4, subfamily b, polypeptide 1 | 0.266 | |
| Adh7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 0.250 | |
| Upp2 | uridine phosphorylase 2 | 0.249 | |
| Nr1i3 | nuclear receptor subfamily 1, group I, member 3 | 0.249 | |
| Apoh | apolipoprotein H | 0.248 | |
| Cyp7a1 | cytochrome P450, family 7, subfamily a, polypeptide 1 | 0.238 | |
| Slc22a18 | solute carrier family 22 (organic cation transporter), member 18 | 0.236 | |
| Cyp2g1 | cytochrome P450, family 2, subfamily g, polypeptide 1 | 0.197 | |
| Slc17a1 | solute carrier family 17 (sodium phosphate), member 1 | 0.191 | |
| Timd2 | T-cell immunoglobulin and mucin domain containing 2 | 0.182 | |
| Serpina6 | serine (or cysteine) peptidase inhibitor, clade A, member 6 | 0.172 | |
| Cyp8b1 | cytochrome P450, family 8, subfamily b, polypeptide 1 | 0.172 | |
| Slc10a1 | solute carrier family 10 (sodium/bile acid cotransporter family), member 1 | 0.159 | |
| F9 | coagulation factor IX | 0.157 | |
| Otc | ornithine transcarbamylase | 0.145 | |
| Fmo3 | flavin containing monooxygenase 3 | 0.142 | |
| Cyp3a25 | cytochrome P450, family 3, subfamily a, polypeptide 25 | 0.140 | |
| Hamp | hepcidin antimicrobial peptide | 0.131 | |
| Ppl | periplakin | 0.126 | |
| Ugt2a3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | 0.124 | |
| Slc27a5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.124 | |
| Aadac | arylacetamide deacetylase (esterase) | 0.118 | |
| F13b | coagulation factor XIII, beta subunit | 0.110 | |
| C9 | complement component 9 | 0.109 | |
| Dmgdh | dimethylglycine dehydrogenase precursor | 0.101 | |
| Hsd3b3 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 | 0.101 | |
| Akr1d1 | aldo-keto reductase family 1, member D1 | 0.100 | |
| Abcc2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.099 | |
| Slc6a20b | solute carrier family 6 (neurotransmitter transporter), member 20B | 0.098 | |
| Pon1 | paraoxonase 1 | 0.092 | |
| Tat | tyrosine aminotransferase | 0.091 | |
| Sult1d1 | sulfotransferase family 1D, member 1 | 0.091 | |
| Pck1 | phosphoenolpyruvate carboxykinase 1, cytosolic | 0.088 | |
| Inhbc | inhibin beta-C | 0.086 | |
| Pik3c2g | phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide | 0.084 | |
| Gsta2 | glutathione S-transferase, alpha 2 (Yc2) | 0.084 | |
| Slc17a3 | solute carrier family 17 (sodium phosphate), member 3 | 0.081 | |
| Ces1d | carboxylesterase 1D | 0.080 | |
| Fmo1 | flavin containing monooxygenase 1 | 0.075 | |
| Apoc4 | apolipoprotein C-IV | 0.075 | |
| Cyp2c70 | cytochrome P450, family 2, subfamily c, polypeptide 70 | 0.073 | |
| Cyp2j5 | cytochrome P450, family 2, subfamily j, polypeptide 5 | 0.071 | |
| Vnn3 | vanin 3 | 0.070 | |
| Bche | butyrylcholinesterase | 0.064 | |
| Ugt3a2 | UDP glycosyltransferases 3 family, polypeptide A2 | 0.063 | |
| Krt6b | keratin 6B | 0.063 | |
| Slc2a2 | solute carrier family 2 (facilitated glucose transporter), member 2 | 0.063 | |
| Tdo2 | tryptophan 2,3-dioxygenase | 0.062 | |
| Cfhr1 | complement factor H-related 1 | 0.062 | |
| Afm | afamin | 0.061 | |
| Cyp4a31 | cytochrome P450, family 4, subfamily a, polypeptide 31 | 0.059 | |
| Dct | dopachrome tautomerase | 0.059 | |
| Slco1b2 | solute carrier organic anion transporter family, member 1b2 | 0.056 | |
| Hc | hemolytic complement | 0.056 | |
| Krtap4-16 | keratin associated protein 4-16 | 0.054 | |
| Serpina1c | serine (or cysteine) peptidase inhibitor, clade A, member 1C | 0.053 | |
| Acsm2 | acyl-CoA synthetase medium-chain family member 2 | 0.052 | |
| Cyp1a2 | cytochrome P450, family 1, subfamily a, polypeptide 2 | 0.051 | |
| Cyp4a12a | cytochrome P450, family 4, subfamily a, polypeptide 12a | 0.050 | |
| Hrg | histidine-rich glycoprotein | 0.049 | |
| Krtap5-1 | keratin associated protein 5-1 | 0.048 | |
| Ces1g | carboxylesterase 1G | 0.048 | |
| BC089597 | cDNA sequence BC089597 | 0.046 | |
| Lce1i | late cornified envelope 1I | 0.046 | |
| Olfr67 | olfactory receptor 67 | 0.045 | |
| Hoga1 | 4-hydroxy-2-oxoglutarate aldolase 1 | 0.044 | |
| Serpina3k | serine (or cysteine) peptidase inhibitor, clade A, member 3K | 0.043 |