IMP
Process View
The network for 'vitamin d3 metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
vitamin d3 metabolic process
The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol.
| Name | Description | Probability | Func Analog Organism |
|---|
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Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CYP3A7 | cytochrome P450, family 3, subfamily A, polypeptide 7 | 0.977 | |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.711 | |
| CYP3A43 | cytochrome P450, family 3, subfamily A, polypeptide 43 | 0.651 | |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 | 0.483 | |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 | 0.289 | |
| MASP2 | mannan-binding lectin serine peptidase 2 | 0.029 | |
| SMAD9 | SMAD family member 9 | 0.023 | |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 | 0.016 | |
| AADAC | arylacetamide deacetylase (esterase) | 0.012 | |
| F9 | coagulation factor IX | 0.012 | |
| C8A | complement component 8, alpha polypeptide | 0.012 |
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Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Cyp2c29 | cytochrome P450, family 2, subfamily c, polypeptide 29 | 0.999 | |
| Cyp2b9 | cytochrome P450, family 2, subfamily b, polypeptide 9 | 0.998 | |
| Otc | ornithine transcarbamylase | 0.996 | |
| Cyp2c38 | cytochrome P450, family 2, subfamily c, polypeptide 38 | 0.991 | |
| Cyp2c39 | cytochrome P450, family 2, subfamily c, polypeptide 39 | 0.989 | |
| Cyp3a11 | cytochrome P450, family 3, subfamily a, polypeptide 11 | 0.987 | |
| Cps1 | carbamoyl-phosphate synthetase 1 | 0.985 | |
| Cyp2a12 | cytochrome P450, family 2, subfamily a, polypeptide 12 | 0.977 | |
| Cyp3a25 | cytochrome P450, family 3, subfamily a, polypeptide 25 | 0.964 | |
| Cyp4a14 | cytochrome P450, family 4, subfamily a, polypeptide 14 | 0.960 | |
| Nr1i2 | nuclear receptor subfamily 1, group I, member 2 | 0.956 | |
| Ugt2b1 | UDP glucuronosyltransferase 2 family, polypeptide B1 | 0.941 | |
| Cyp2c54 | cytochrome P450, family 2, subfamily c, polypeptide 54 | 0.905 | |
| Ces2a | carboxylesterase 2A | 0.844 | |
| Sult1d1 | sulfotransferase family 1D, member 1 | 0.833 | |
| Cyp3a44 | cytochrome P450, family 3, subfamily a, polypeptide 44 | 0.826 | |
| Crp | C-reactive protein, pentraxin-related | 0.815 | |
| G6pc | glucose-6-phosphatase, catalytic | 0.763 | |
| Upp2 | uridine phosphorylase 2 | 0.721 | |
| Ugt2b34 | UDP glucuronosyltransferase 2 family, polypeptide B34 | 0.683 | |
| Fmo3 | flavin containing monooxygenase 3 | 0.681 | |
| Cyp2c68 | cytochrome P450, family 2, subfamily c, polypeptide 68 | 0.674 | |
| Akr1d1 | aldo-keto reductase family 1, member D1 | 0.667 | |
| Sult1b1 | sulfotransferase family 1B, member 1 | 0.642 | |
| Cyp2g1 | cytochrome P450, family 2, subfamily g, polypeptide 1 | 0.627 | |
| Cml2 | camello-like 2 | 0.621 | |
| Hsd3b2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 | 0.595 | |
| Serpina6 | serine (or cysteine) peptidase inhibitor, clade A, member 6 | 0.594 | |
| Hsd3b3 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 | 0.577 | |
| Cyp2c50 | cytochrome P450, family 2, subfamily c, polypeptide 50 | 0.566 | |
| Ugt2a3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | 0.555 | |
| Cyp7a1 | cytochrome P450, family 7, subfamily a, polypeptide 1 | 0.551 | |
| Azgp1 | alpha-2-glycoprotein 1, zinc | 0.546 | |
| Slc10a1 | solute carrier family 10 (sodium/bile acid cotransporter family), member 1 | 0.543 | |
| Gsta2 | glutathione S-transferase, alpha 2 (Yc2) | 0.534 | |
| Keg1 | kidney expressed gene 1 | 0.528 | |
| Ces1g | carboxylesterase 1G | 0.511 | |
| Abcc2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.483 | |
| Cyp2b10 | cytochrome P450, family 2, subfamily b, polypeptide 10 | 0.483 | |
| Cyp2d9 | cytochrome P450, family 2, subfamily d, polypeptide 9 | 0.472 | |
| Aadac | arylacetamide deacetylase (esterase) | 0.463 | |
| Cyp2c37 | cytochrome P450, family 2. subfamily c, polypeptide 37 | 0.462 | |
| Nr5a2 | nuclear receptor subfamily 5, group A, member 2 | 0.455 | |
| Pik3c2g | phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide | 0.447 | |
| Slc22a1 | solute carrier family 22 (organic cation transporter), member 1 | 0.423 | |
| Hpd | 4-hydroxyphenylpyruvic acid dioxygenase | 0.422 | |
| Bche | butyrylcholinesterase | 0.411 | |
| Aldob | aldolase B, fructose-bisphosphate | 0.406 | |
| Cyp1a2 | cytochrome P450, family 1, subfamily a, polypeptide 2 | 0.399 | |
| Hrg | histidine-rich glycoprotein | 0.399 | |
| Slco1b2 | solute carrier organic anion transporter family, member 1b2 | 0.398 | |
| Pigr | polymeric immunoglobulin receptor | 0.382 | |
| Fmo5 | flavin containing monooxygenase 5 | 0.373 | |
| Inmt | indolethylamine N-methyltransferase | 0.369 | |
| Iyd | iodotyrosine deiodinase | 0.358 | |
| Cyp2d10 | cytochrome P450, family 2, subfamily d, polypeptide 10 | 0.349 | |
| Pck1 | phosphoenolpyruvate carboxykinase 1, cytosolic | 0.346 | |
| Acot12 | acyl-CoA thioesterase 12 | 0.345 | |
| Rdh7 | retinol dehydrogenase 7 | 0.343 | |
| Cyp3a13 | cytochrome P450, family 3, subfamily a, polypeptide 13 | 0.332 | |
| F13b | coagulation factor XIII, beta subunit | 0.330 | |
| Slc2a2 | solute carrier family 2 (facilitated glucose transporter), member 2 | 0.329 | |
| Cyp2c55 | cytochrome P450, family 2, subfamily c, polypeptide 55 | 0.326 | |
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.313 | |
| Agmat | agmatine ureohydrolase (agmatinase) | 0.307 | |
| Adh7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 0.307 | |
| Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.306 | |
| BC089597 | cDNA sequence BC089597 | 0.284 | |
| Slc27a5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.281 | |
| Baat | bile acid-Coenzyme A: amino acid N-acyltransferase | 0.277 | |
| Apoc3 | apolipoprotein C-III | 0.275 | |
| Akr1c6 | aldo-keto reductase family 1, member C6 | 0.260 | |
| Slc12a1 | solute carrier family 12, member 1 | 0.252 | |
| Cyp3a41b | cytochrome P450, family 3, subfamily a, polypeptide 41B | 0.250 | |
| Lce1i | late cornified envelope 1I | 0.235 | |
| Ces2e | carboxylesterase 2E | 0.232 | |
| Cfhr1 | complement factor H-related 1 | 0.230 | |
| Gsta3 | glutathione S-transferase, alpha 3 | 0.223 | |
| Sult2a2 | sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2 | 0.218 | |
| Pon1 | paraoxonase 1 | 0.207 | |
| Mup19 | major urinary protein 19 | 0.193 | |
| Defb1 | defensin beta 1 | 0.193 | |
| AB056442 | cDNA sequence AB056442 | 0.193 | |
| Olfr67 | olfactory receptor 67 | 0.192 | |
| Mug2 | murinoglobulin 2 | 0.188 | |
| Gstm3 | glutathione S-transferase, mu 3 | 0.186 | |
| Ces1d | carboxylesterase 1D | 0.182 | |
| Acox2 | acyl-Coenzyme A oxidase 2, branched chain | 0.181 | |
| Dct | dopachrome tautomerase | 0.180 | |
| Ces1e | carboxylesterase 1E | 0.179 | |
| Glyat | glycine-N-acyltransferase | 0.179 | |
| Prlr | prolactin receptor | 0.178 | |
| Ces1c | carboxylesterase 1C | 0.174 | |
| Cyp2c70 | cytochrome P450, family 2, subfamily c, polypeptide 70 | 0.170 | |
| Ugt2b36 | UDP glucuronosyltransferase 2 family, polypeptide B36 | 0.168 | |
| Cyp4a31 | cytochrome P450, family 4, subfamily a, polypeptide 31 | 0.166 | |
| Vsig4 | V-set and immunoglobulin domain containing 4 | 0.166 | |
| Tmprss15 | transmembrane protease, serine 15 | 0.165 | |
| Krtap6-1 | keratin associated protein 6-1 | 0.164 | |
| Cyp2b13 | cytochrome P450, family 2, subfamily b, polypeptide 13 | 0.161 |
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Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| LOC293989 | cytochrome P450-like | 0.539 | |
| Cyp3a18 | cytochrome P450, family 3, subfamily a, polypeptide 18 | 0.359 | |
| Ugt2b | UDP glycosyltransferase 2 family, polypeptide B | 0.208 | |
| Ugt2b1 | UDP glucuronosyltransferase 2 family, polypeptide B1 | 0.163 | |
| Cyp1a1 | cytochrome P450, family 1, subfamily a, polypeptide 1 | 0.098 | |
| Abcb11 | ATP-binding cassette, subfamily B (MDR/TAP), member 11 | 0.090 | |
| Sult1c3 | sulfotransferase family, cytosolic, 1C, member 3 | 0.073 | |
| Sult1b1 | sulfotransferase family, cytosolic, 1B, member 1 | 0.066 | |
| Ugt2b5 | UDP glucuronosyltransferase 2 family, polypeptide B5 | 0.048 | |
| Cyp3a2 | cytochrome P450, family 3, subfamily a, polypeptide 2 | 0.038 | |
| LOC100365112 | carboxylesterase-like | 0.037 | |
| Cyp2b1 | cytochrome P450, family 2, subfamily b, polypeptide 1 | 0.031 | |
| Cyp2c13 | cytochrome P450, family 2, subfamily c, polypeptide 13 | 0.030 | |
| Akr1c18 | aldo-keto reductase family 1, member C18 | 0.029 | |
| Sult1c2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.028 | |
| Cyp2a2 | cytochrome P450, family 2, subfamily a, polypeptide 2 | 0.027 | |
| Cyp2c11 | cytochrome P450, subfamily 2, polypeptide 11 | 0.027 | |
| Si | sucrase-isomaltase (alpha-glucosidase) | 0.024 | |
| Ces1f | carboxylesterase 1F | 0.022 | |
| Sult2a1 | sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 0.021 | |
| Cyp2c22 | cytochrome P450, family 2, subfamily c, polypeptide 22 | 0.020 | |
| Sult1e1 | sulfotransferase family 1E, estrogen-preferring, member 1 | 0.019 | |
| Apob | apolipoprotein B | 0.019 | |
| Fut9 | fucosyltransferase 9 (alpha (1,3) fucosyltransferase) | 0.019 | |
| Kl | Klotho | 0.018 | |
| ND4 | NADH dehydrogenase subunit 4 | 0.018 | |
| Pfkfb1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 0.017 | |
| LOC494499 | LOC494499 protein | 0.016 | |
| LOC100361547 | Cytochrome P450, family 2, subfamily c, polypeptide 7-like | 0.016 | |
| LOC100360403 | ATP-binding cassette, sub-family C, member 9-like | 0.015 | |
| Nr0b2 | nuclear receptor subfamily 0, group B, member 2 | 0.015 | |
| Dpyd | dihydropyrimidine dehydrogenase | 0.015 | |
| Adhfe1 | alcohol dehydrogenase, iron containing, 1 | 0.014 | |
| Selp | selectin P | 0.014 | |
| Cyp4f1 | cytochrome P450, family 4, subfamily f, polypeptide 1 | 0.014 | |
| Spink1 | serine peptidase inhibitor, Kazal type 1 | 0.014 | |
| Cyp2d4 | cytochrome P450, family 2, subfamily d, polypeptide 4 | 0.013 | |
| Slc6a17 | solute carrier family 6 (neurotransmitter transporter), member 17 | 0.013 | |
| Cyp3a9 | cytochrome P450, family 3, subfamily a, polypeptide 9 | 0.013 | |
| Ugt2b37 | UDP-glucuronosyltransferase 2 family, member 37 | 0.012 | |
| Slc9a3 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 | 0.012 | |
| Cyp2d2 | cytochrome P450, family 2, subfamily d, polypeptide 2 | 0.012 | |
| Cyp4b1 | cytochrome P450, family 4, subfamily b, polypeptide 1 | 0.012 | |
| Pigr | polymeric immunoglobulin receptor | 0.012 | |
| Cyp2c12 | cytochrome P450, family 2, subfamily c, polypeptide 12 | 0.011 | |
| Klrh1 | killer cell lectin-like receptor subfamily H, member 1 | 0.011 | |
| Slco1a1 | solute carrier organic anion transporter family, member 1a1 | 0.011 | |
| Hsd3b5 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 | 0.011 | |
| Cyp1a2 | cytochrome P450, family 1, subfamily a, polypeptide 2 | 0.011 | |
| Gabra1 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 0.011 | |
| Sult2al1 | sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1 | 0.010 | |
| Cdcp1 | CUB domain containing protein 1 | 0.010 | |
| Txnrd2 | thioredoxin reductase 2 | 0.010 | |
| As3mt | arsenic (+3 oxidation state) methyltransferase | 0.010 |