The network for 'positive regulation of gastrulation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of gastrulation

Any process that activates or increases the frequency, rate or extent of gastrulation.

Drosophila melanogaster
Name Description Probability Func Analog Organism
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
osr1 odd-skipped related 1 (Drosophila) 0.913
tbx5a T-box 5a 0.831
foxa3 forkhead box A3 0.212
efnb2a ephrin B2a 0.205
foxj1a forkhead box J1a 0.203
shhb sonic hedgehog b 0.198
osr2 odd-skipped related 2 (Drosophila) 0.188
foxn4 forkhead box N4 0.182
jag1b jagged 1b 0.180
sox2 SRY-box containing gene 2 0.178
foxa1 forkhead box A1 0.176
cdh2 cadherin 2, neuronal 0.172
hnf1ba HNF1 homeobox Ba 0.171
etv2 ets variant gene 2 0.155
bmp4 bone morphogenetic protein 4 0.153
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.147
wt1b wilms tumor 1b 0.139
notch3 notch homolog 3 0.135
notch1a notch homolog 1a 0.130
pcdh18b protocadherin 18b 0.130
nkx2.2a NK2 transcription factor related 2a 0.128
lhx5 LIM homeobox 5 0.119
dlx3b distal-less homeobox gene 3b 0.118
raraa retinoic acid receptor, alpha a 0.114
rfx2 regulatory factor X, 2 (influences HLA class II expression) 0.107
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.100
jag2 jagged 2 0.095
twist2 twist2 0.091
nkd1 naked cuticle homolog 1 (Drosophila) 0.089
lmx1b.2 LIM homeobox transcription factor 1, beta 2 0.087
foxb1.2 forkhead box B1.2 0.085
gsc goosecoid 0.082
fli1a friend leukemia integration 1a 0.081
scube2 signal peptide, CUB domain, EGF-like 2 0.080
wnt1 wingless-type MMTV integration site family, member 1 0.078
hnf1bb HNF1 homeobox Bb 0.077
mecom MDS1 and EVI1 complex locus 0.074
wnt9a wingless-type MMTV integration site family, member 9A 0.073
dld deltaD 0.069
foxj1b forkhead box J1b 0.067
gata6 GATA-binding protein 6 0.066
nkx6.1 NK6 transcription factor related, locus 1 (Drosophila) 0.063
foxc1a forkhead box C1a 0.062
dact2 dapper homolog 2, antagonist of beta-catenin (xenopus) 0.060
col2a1a collagen type II, alpha-1a 0.059
ascl1a achaete-scute complex-like 1a (Drosophila) 0.058
dcc deleted in colorectal carcinoma 0.058
shha sonic hedgehog a 0.058
hhex hematopoietically expressed homeobox 0.057
meis3 myeloid ecotropic viral integration site 3 0.056
neurod4 neurogenic differentiation 4 0.055
gh1 growth hormone 1 0.054
bmper BMP binding endothelial regulator 0.054
barhl2 BarH-like 2 0.051
gyltl1b glycosyltransferase-like 1b 0.050
th tyrosine hydroxylase 0.048
dlc deltaC 0.047
kdrl kinase insert domain receptor like 0.046
irx1b iroquois homeobox protein 1, b 0.045
dla deltaA 0.044
gata2a GATA-binding protein 2a 0.044
pitx2 paired-like homeodomain transcription factor 2 0.043
elavl3 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) 0.043
myod1 myogenic differentiation 1 0.042
eya1 eyes absent homolog 1 0.042
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.042
tshb thyroid stimulating hormone, beta subunit 0.041
epha4a eph receptor A4a 0.041
emx1 empty spiracles homeobox 1 0.040
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.039
twist1a twist1a 0.039
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.039
wif1 wnt inhibitory factor 1 0.039
dbx1a developing brain homeobox 1a 0.038
foxd3 forkhead box D3 0.037
pea3 ETS-domain transcription factor pea3 0.037
lhx2b LIM homeobox 2b 0.037
hoxc4a homeo box C4a 0.037
dlx2a distal-less homeobox gene 2a 0.036
neo1 neogenin 1 0.035
six4b sine oculis homeobox homolog 4b 0.035
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.034
ascl1b achaete-scute complex-like 1b (Drosophila) 0.033
hoxb1a homeo box B1a 0.033
olig2 oligodendrocyte lineage transcription factor 2 0.033
sim1a single-minded homolog 1a (Drosophila) 0.032
pkd2 polycystic kidney disease 2 0.032
her9 hairy-related 9 0.032
pbx4 pre-B-cell leukemia transcription factor 4 0.032
hoxd3a homeo box D3a 0.031
nkx2.3 NK2 transcription factor related 3 0.030
ptch1 patched 1 0.030
gbx2 gastrulation brain homeo box 2 0.028
pcdh18a protocadherin 18a 0.028
gata1a GATA binding protein 1a 0.028
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.027
foxp2 forkhead box P2 0.027
ptgs1 prostaglandin-endoperoxide synthase 1 0.027
dkk1b dickkopf 1b 0.027
fgf3 fibroblast growth factor 3 0.027
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Homo sapiens
Name Description Probability Func Analog Organism
NOTCH3 notch 3 0.455
JAG1 jagged 1 0.199
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.117
EIF3L eukaryotic translation initiation factor 3, subunit L 0.103
EEF2 eukaryotic translation elongation factor 2 0.063
FZD1 frizzled homolog 1 (Drosophila) 0.058
MAML1 mastermind-like 1 (Drosophila) 0.056
EIF3D eukaryotic translation initiation factor 3, subunit D 0.051
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.049
PRPF6 PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) 0.030
EIF3F eukaryotic translation initiation factor 3, subunit F 0.028
RPL3 ribosomal protein L3 0.028
RPL8 ribosomal protein L8 0.020
VHL von Hippel-Lindau tumor suppressor 0.019
SPEN spen homolog, transcriptional regulator (Drosophila) 0.016
WDR83 WD repeat domain 83 0.015
DYNLL1 dynein, light chain, LC8-type 1 0.015
DGCR14 DiGeorge syndrome critical region gene 14 0.013
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.013
RPL27A ribosomal protein L27a 0.012
XIAP X-linked inhibitor of apoptosis 0.012
NOTCH2 notch 2 0.011
EIF3H eukaryotic translation initiation factor 3, subunit H 0.011
QARS glutaminyl-tRNA synthetase 0.010
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Otx2 orthodenticle homolog 2 (Drosophila) 0.986
Pax6 paired box gene 6 0.928
Shh sonic hedgehog 0.890
Pax2 paired box gene 2 0.830
Pax3 paired box gene 3 0.641
Foxc1 forkhead box C1 0.586
Lhx1 LIM homeobox protein 1 0.490
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.413
Neurod1 neurogenic differentiation 1 0.362
Isl1 ISL1 transcription factor, LIM/homeodomain 0.324
Gli3 GLI-Kruppel family member GLI3 0.309
Foxg1 forkhead box G1 0.274
En1 engrailed 1 0.262
Pitx2 paired-like homeodomain transcription factor 2 0.228
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.201
Foxa2 forkhead box A2 0.201
Neurog2 neurogenin 2 0.187
Ptf1a pancreas specific transcription factor, 1a 0.178
Pou4f2 POU domain, class 4, transcription factor 2 0.173
Emx2 empty spiracles homolog 2 (Drosophila) 0.170
Emx1 empty spiracles homolog 1 (Drosophila) 0.170
Hand2 heart and neural crest derivatives expressed transcript 2 0.159
Lhx9 LIM homeobox protein 9 0.159
Fgf8 fibroblast growth factor 8 0.134
Hoxa1 homeobox A1 0.106
Hoxd11 homeobox D11 0.101
Tbx1 T-box 1 0.101
Gbx2 gastrulation brain homeobox 2 0.097
Hoxd13 homeobox D13 0.082
Tcfap2a transcription factor AP-2, alpha 0.068
Msx1 homeobox, msh-like 1 0.067
Foxc2 forkhead box C2 0.061
Hoxd3 homeobox D3 0.052
Insm1 insulinoma-associated 1 0.048
Pax8 paired box gene 8 0.046
Gsc goosecoid homeobox 0.042
Wt1 Wilms tumor 1 homolog 0.041
Gdnf glial cell line derived neurotrophic factor 0.039
Hmx1 H6 homeobox 1 0.038
Onecut1 one cut domain, family member 1 0.038
Fgfr2 fibroblast growth factor receptor 2 0.037
Dlx2 distal-less homeobox 2 0.037
Pax9 paired box gene 9 0.037
Dlx1 distal-less homeobox 1 0.036
Pdx1 pancreatic and duodenal homeobox 1 0.035
Hes5 hairy and enhancer of split 5 (Drosophila) 0.035
Lmx1b LIM homeobox transcription factor 1 beta 0.035
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.033
Chd7 chromodomain helicase DNA binding protein 7 0.030
Pitx1 paired-like homeodomain transcription factor 1 0.029
Sox2 SRY-box containing gene 2 0.029
Sox11 SRY-box containing gene 11 0.029
Nkx2-1 NK2 homeobox 1 0.028
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.028
T brachyury 0.028
Hmx3 H6 homeobox 3 0.027
Prrx2 paired related homeobox 2 0.027
Gata4 GATA binding protein 4 0.027
Eya1 eyes absent 1 homolog (Drosophila) 0.027
Lmx1a LIM homeobox transcription factor 1 alpha 0.026
Dlx5 distal-less homeobox 5 0.025
Lhx3 LIM homeobox protein 3 0.024
Col22a1 collagen, type XXII, alpha 1 0.024
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.023
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.022
Lhx5 LIM homeobox protein 5 0.021
Zic2 zinc finger protein of the cerebellum 2 0.021
Hand1 heart and neural crest derivatives expressed transcript 1 0.021
Hoxb1 homeobox B1 0.020
Nr2e1 nuclear receptor subfamily 2, group E, member 1 0.019
Tlx3 T-cell leukemia, homeobox 3 0.019
Evx1 even skipped homeotic gene 1 homolog 0.019
Pou4f3 POU domain, class 4, transcription factor 3 0.019
Dab1 disabled homolog 1 (Drosophila) 0.018
Mecom MDS1 and EVI1 complex locus 0.018
Nkx1-2 NK1 transcription factor related, locus 2 (Drosophila) 0.017
Hoxa2 homeobox A2 0.017
Foxb1 forkhead box B1 0.017
Neurog3 neurogenin 3 0.017
Emid2 EMI domain containing 2 0.017
Gli2 GLI-Kruppel family member GLI2 0.017
Tcfap2b transcription factor AP-2 beta 0.017
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.016
Hoxa11 homeobox A11 0.016
Nkx6-1 NK6 homeobox 1 0.016
Arx aristaless related homeobox 0.016
Bnc1 basonuclin 1 0.016
Foxa1 forkhead box A1 0.015
Phox2b paired-like homeobox 2b 0.015
Tcf21 transcription factor 21 0.015
Nkx3-2 NK3 homeobox 2 0.014
Zic1 zinc finger protein of the cerebellum 1 0.014
Hoxd1 homeobox D1 0.014
Prph2 peripherin 2 0.014
Atoh1 atonal homolog 1 (Drosophila) 0.013
Otx1 orthodenticle homolog 1 (Drosophila) 0.013
Uncx UNC homeobox 0.013
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.013
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.013
Pou3f3 POU domain, class 3, transcription factor 3 0.013
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism