The network for 'positive regulation of activation of membrane attack complex' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of activation of membrane attack complex

Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.

Drosophila melanogaster
Name Description Probability Func Analog Organism
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.826
Lyz2 lysozyme 2 0.791
Itih4 inter alpha-trypsin inhibitor, heavy chain 4 0.757
C9 complement component 9 0.706
Hc hemolytic complement 0.517
1300017J02Rik RIKEN cDNA 1300017J02 gene 0.444
Il10 interleukin 10 0.432
Lrg1 leucine-rich alpha-2-glycoprotein 1 0.428
Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 0.418
Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N 0.406
Proc protein C 0.390
Apcs serum amyloid P-component 0.375
Apoe apolipoprotein E 0.372
Ifng interferon gamma 0.367
Plg plasminogen 0.331
Fas Fas (TNF receptor superfamily member 6) 0.300
Tnf tumor necrosis factor 0.296
Itih1 inter-alpha trypsin inhibitor, heavy chain 1 0.270
Fgg fibrinogen gamma chain 0.247
Cd28 CD28 antigen 0.244
Serpina10 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 0.240
Saa4 serum amyloid A 4 0.234
Slc27a5 solute carrier family 27 (fatty acid transporter), member 5 0.230
Pzp pregnancy zone protein 0.225
C1ra complement component 1, r subcomponent A 0.222
Gc group specific component 0.209
Ahsg alpha-2-HS-glycoprotein 0.205
1100001G20Rik RIKEN cDNA 1100001G20 gene 0.195
Creb3l3 cAMP responsive element binding protein 3-like 3 0.194
Hpx hemopexin 0.181
Hp haptoglobin 0.180
Itih3 inter-alpha trypsin inhibitor, heavy chain 3 0.168
Ikbkg inhibitor of kappaB kinase gamma 0.166
Rag2 recombination activating gene 2 0.164
Kng1 kininogen 1 0.159
F7 coagulation factor VII 0.153
Mug2 murinoglobulin 2 0.152
Apof apolipoprotein F 0.151
Lipc lipase, hepatic 0.150
Ces3a carboxylesterase 3A 0.142
Foxp3 forkhead box P3 0.142
Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 0.141
C8a complement component 8, alpha polypeptide 0.137
F9 coagulation factor IX 0.125
C3 complement component 3 0.123
Rab27a RAB27A, member RAS oncogene family 0.121
F12 coagulation factor XII (Hageman factor) 0.117
Hrg histidine-rich glycoprotein 0.113
Stat3 signal transducer and activator of transcription 3 0.111
Cp ceruloplasmin 0.109
Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide 0.107
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.100
Alb albumin 0.098
Gfi1 growth factor independent 1 0.094
Il2 interleukin 2 0.093
Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 0.091
F2 coagulation factor II 0.089
Cfb complement factor B 0.086
F11 coagulation factor XI 0.082
Il27ra interleukin 27 receptor, alpha 0.082
Rag1 recombination activating gene 1 0.079
Tlr2 toll-like receptor 2 0.075
Fga fibrinogen alpha chain 0.075
Serpina3m serine (or cysteine) peptidase inhibitor, clade A, member 3M 0.074
Fcgr2b Fc receptor, IgG, low affinity IIb 0.072
C2 complement component 2 (within H-2S) 0.072
Mbl1 mannose-binding lectin (protein A) 1 0.071
Saa2 serum amyloid A 2 0.071
Cd19 CD19 antigen 0.070
Serpinf2 serine (or cysteine) peptidase inhibitor, clade F, member 2 0.069
C8b complement component 8, beta polypeptide 0.069
F10 coagulation factor X 0.069
Lyst lysosomal trafficking regulator 0.066
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.066
Ambp alpha 1 microglobulin/bikunin 0.065
Dpys dihydropyrimidinase 0.064
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.063
Cfi complement component factor i 0.062
Mup3 major urinary protein 3 0.061
Azgp1 alpha-2-glycoprotein 1, zinc 0.058
Cyp2c70 cytochrome P450, family 2, subfamily c, polypeptide 70 0.058
Nlrp3 NLR family, pyrin domain containing 3 0.058
Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 0.057
Aadac arylacetamide deacetylase (esterase) 0.055
Lcn2 lipocalin 2 0.053
Hao1 hydroxyacid oxidase 1, liver 0.052
Stx11 syntaxin 11 0.052
Fgb fibrinogen beta chain 0.052
Akr1c6 aldo-keto reductase family 1, member C6 0.052
Lbp lipopolysaccharide binding protein 0.050
Cfh complement component factor h 0.049
Gckr glucokinase regulatory protein 0.048
Rdh7 retinol dehydrogenase 7 0.046
Cps1 carbamoyl-phosphate synthetase 1 0.046
Ces1c carboxylesterase 1C 0.046
Cpn2 carboxypeptidase N, polypeptide 2 0.045
Hal histidine ammonia lyase 0.045
Apoa1 apolipoprotein A-I 0.044
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.043
Serpind1 serine (or cysteine) peptidase inhibitor, clade D, member 1 0.043
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism