The network for 'polyamine catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

polyamine catabolic process

The chemical reactions and pathways resulting in the breakdown of polyamines, any organic compound containing two or more amino groups.

Name Description Probability Func Analog Organism
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.839
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.801
C2orf18 chromosome 2 open reading frame 18 0.083
UNC119 unc-119 homolog (C. elegans) 0.013
IGSF21 immunoglobin superfamily, member 21 0.013
NUPR1 nuclear protein, transcriptional regulator, 1 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Gstm1 glutathione S-transferase, mu 1 0.252
Gsta3 glutathione S-transferase, alpha 3 0.208
Selenbp1 selenium binding protein 1 0.086
Ces1d carboxylesterase 1D 0.072
Adh1 alcohol dehydrogenase 1 (class I) 0.071
Sirt3 sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae) 0.056
Gsta4 glutathione S-transferase, alpha 4 0.049
Fmo5 flavin containing monooxygenase 5 0.048
Ces2g carboxylesterase 2G 0.045
Gstm6 glutathione S-transferase, mu 6 0.044
Sult1a1 sulfotransferase family 1A, phenol-preferring, member 1 0.041
Ephx2 epoxide hydrolase 2, cytoplasmic 0.037
Gstt1 glutathione S-transferase, theta 1 0.034
Agmo alkylglycerol monooxygenase 0.031
Pon1 paraoxonase 1 0.031
Rbp4 retinol binding protein 4, plasma 0.030
Fmo1 flavin containing monooxygenase 1 0.028
Ivd isovaleryl coenzyme A dehydrogenase 0.028
Akr1c13 aldo-keto reductase family 1, member C13 0.027
Pcbd1 pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1 0.027
Pxmp2 peroxisomal membrane protein 2 0.026
Cdo1 cysteine dioxygenase 1, cytosolic 0.025
Hpgd hydroxyprostaglandin dehydrogenase 15 (NAD) 0.025
Clu clusterin 0.024
Tst thiosulfate sulfurtransferase, mitochondrial 0.023
Slc16a7 solute carrier family 16 (monocarboxylic acid transporters), member 7 0.021
Gstm2 glutathione S-transferase, mu 2 0.021
Mpzl2 myelin protein zero-like 2 0.020
Amy1 amylase 1, salivary 0.020
Fah fumarylacetoacetate hydrolase 0.019
Slc46a3 solute carrier family 46, member 3 0.018
Sec16b SEC16 homolog B (S. cerevisiae) 0.018
Scd1 stearoyl-Coenzyme A desaturase 1 0.018
Cmbl carboxymethylenebutenolidase-like (Pseudomonas) 0.018
Aox1 aldehyde oxidase 1 0.017
Gstk1 glutathione S-transferase kappa 1 0.017
Alas2 aminolevulinic acid synthase 2, erythroid 0.017
Tmem56 transmembrane protein 56 0.017
Ephx1 epoxide hydrolase 1, microsomal 0.017
Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 0.016
Pafah2 platelet-activating factor acetylhydrolase 2 0.016
Hnmt histamine N-methyltransferase 0.015
Aspa aspartoacylase 0.015
Xylb xylulokinase homolog (H. influenzae) 0.015
Sepp1 selenoprotein P, plasma, 1 0.015
Cyp2j6 cytochrome P450, family 2, subfamily j, polypeptide 6 0.015
Galm galactose mutarotase 0.015
Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.015
Cd36 CD36 antigen 0.015
Klf15 Kruppel-like factor 15 0.015
Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 0.014
Oat ornithine aminotransferase 0.014
Sult1d1 sulfotransferase family 1D, member 1 0.014
Reep6 receptor accessory protein 6 0.014
Vnn1 vanin 1 0.014
Msra methionine sulfoxide reductase A 0.014
Hebp1 heme binding protein 1 0.014
Cyb5 cytochrome b-5 0.013
Slc27a2 solute carrier family 27 (fatty acid transporter), member 2 0.013
Lyplal1 lysophospholipase-like 1 0.013
9030617O03Rik RIKEN cDNA 9030617O03 gene 0.013
Arhgef26 Rho guanine nucleotide exchange factor (GEF) 26 0.012
Pon3 paraoxonase 3 0.012
Alas1 aminolevulinic acid synthase 1 0.012
Retsat retinol saturase (all trans retinol 13,14 reductase) 0.012
Lhpp phospholysine phosphohistidine inorganic pyrophosphate phosphatase 0.012
Rassf6 Ras association (RalGDS/AF-6) domain family member 6 0.012
Abhd14b abhydrolase domain containing 14b 0.012
Gpld1 glycosylphosphatidylinositol specific phospholipase D1 0.012
Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 0.012
Ppp1r3b protein phosphatase 1, regulatory (inhibitor) subunit 3B 0.012
Inmt indolethylamine N-methyltransferase 0.012
Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 0.012
Hyi hydroxypyruvate isomerase homolog (E. coli) 0.012
Ppbp pro-platelet basic protein 0.012
Dhrs3 dehydrogenase/reductase (SDR family) member 3 0.012
Rbm47 RNA binding motif protein 47 0.012
Prdx6 peroxiredoxin 6 0.012
Akr1c14 aldo-keto reductase family 1, member C14 0.011
Gclm glutamate-cysteine ligase, modifier subunit 0.011
Naprt1 nicotinate phosphoribosyltransferase domain containing 1 0.011
Dhrs11 dehydrogenase/reductase (SDR family) member 11 0.011
Adhfe1 alcohol dehydrogenase, iron containing, 1 0.011
Maob monoamine oxidase B 0.011
Dpp4 dipeptidylpeptidase 4 0.011
Prodh proline dehydrogenase 0.011
Aldh2 aldehyde dehydrogenase 2, mitochondrial 0.011
Tesk2 testis-specific kinase 2 0.011
Slc47a1 solute carrier family 47, member 1 0.011
Rab30 RAB30, member RAS oncogene family 0.011
Calml4 calmodulin-like 4 0.011
Fam151b family with sequence similarity 151, member B 0.011
Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 0.010
Galk1 galactokinase 1 0.010
Rsc1a1 regulatory solute carrier protein, family 1, member 1 0.010
Mfsd2a major facilitator superfamily domain containing 2A 0.010
Immp2l IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.010
Aldh1b1 aldehyde dehydrogenase 1 family, member B1 0.010
Pygl liver glycogen phosphorylase 0.010
Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism