The network for 'retinal cone cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

retinal cone cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell.

Rattus norvegicus
Name Description Probability Func Analog Organism
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
pax2a paired box gene 2a 0.871
tbx2b T-box 2b 0.855
flh floating head 0.747
tbx2a T-box gene 2a 0.282
pax6b paired box gene 6b 0.275
bmp4 bone morphogenetic protein 4 0.226
bmp2b bone morphogenetic protein 2b 0.211
raraa retinoic acid receptor, alpha a 0.202
otx2 orthodenticle homolog 2 0.168
otx5 orthodenticle homolog 5 0.138
rx3 retinal homeobox gene 3 0.116
foxg1a forkhead box G1a 0.116
rxraa retinoid X receptor, alpha a 0.110
hmx4 H6 family homeobox 4 0.109
tfap2a transcription factor AP-2 alpha 0.098
ahi1 Abelson helper integration site 1 0.097
fezf2 FEZ family zinc finger 2 0.092
vent ventral expressed homeobox 0.092
nr2e3 nuclear receptor subfamily 2, group E, member 3 0.086
her1 hairy-related 1 0.085
neurog1 neurogenin 1 0.082
atoh7 atonal homolog 7 0.081
hoxb2a homeo box B2a 0.078
ift88 intraflagellar transport 88 homolog 0.078
chd chordin 0.076
isl1 islet1 0.074
crx cone-rod homeobox 0.073
meis2.2 myeloid ecotropic viral integration site 2.2 0.071
foxi1 forkhead box I1 0.068
rx2 retinal homeobox gene 2 0.065
irx7 iroquois homeobox protein 7 0.063
tbx5a T-box 5a 0.062
notch1a notch homolog 1a 0.059
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.056
barhl2 BarH-like 2 0.056
gbx2 gastrulation brain homeo box 2 0.055
pde6c phosphodiesterase 6C, cGMP-specific, cone, alpha prime 0.052
six3a sine oculis homeobox homolog 3a 0.050
six3b sine oculis homeobox homolog 3b 0.048
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.043
dlx2a distal-less homeobox gene 2a 0.043
rxrga retinoid x receptor, gamma a 0.042
gdnf glial cell derived neurotrophic factor 0.041
dla deltaA 0.040
tbx20 T-box 20 0.037
ndr2 nodal-related 2 0.037
rorab RAR-related orphan receptor A, paralog b 0.036
gucy2f guanylate cyclase 2F, retinal 0.035
spry1 sprouty homolog 1 (Drosophila) 0.035
irx4b iroquois homeobox protein 4b 0.035
ptf1a pancreas specific transcription factor, 1a 0.034
nkx2.1a NK2 homeobox 1a 0.034
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.033
clrn1 clarin 1 0.033
tbx18 T-box 18 0.032
fgf3 fibroblast growth factor 3 0.032
cyp26a1 cytochrome P450, subfamily XXVIA, polypeptide 1 0.032
eomesa eomesodermin homolog a 0.030
gfi1.2 growth factor independent 1.2 0.029
kif17 kinesin family member 17 0.029
tbx16 T-box gene 16 0.029
eya1 eyes absent homolog 1 0.028
eng2b engrailed 2b 0.028
pcdh8 protocadherin 8 0.028
rx1 retinal homeobox gene 1 0.027
nkx2.3 NK2 transcription factor related 3 0.027
msxe muscle segment homeobox E 0.026
otpb orthopedia homolog b 0.026
gja3 gap junction protein, alpha 3 0.025
shha sonic hedgehog a 0.025
nkx2.5 NK2 transcription factor related 5 0.025
notch1b notch homolog 1b 0.024
neurod neurogenic differentiation 0.024
slc6a8 solute carrier family 6 (neurotransmitter transporter, creatine), member 8 0.024
vsx2 visual system homeobox 2 0.024
bbc3 BCL2 binding component 3 0.024
evx1 even-skipped homeobox 1 0.024
mitfa microphthalmia-associated transcription factor a 0.024
pnx posterior neuron-specific homeobox 0.023
gli1 GLI-Kruppel family member 1 0.023
lhx1a LIM homeobox 1a 0.023
rarab retinoic acid receptor, alpha b 0.023
jag2 jagged 2 0.023
vsx1 visual system homeobox 1 homolog, chx10-like 0.022
mib mind bomb 0.022
lhx3 LIM homeobox 3 0.021
isl2a islet2a 0.021
dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.021
slc25a37 solute carrier family 25, member 37 0.021
myo7aa myosin VIIAa 0.021
mab21l2 mab-21-like 2 0.020
pax8 paired box gene 8 0.020
tll1 tolloid-like 1 0.020
tbx6 T-box gene 6 0.019
ncam1b neural cell adhesion molecule 1b 0.019
her7 hairy and enhancer of split related-7 0.019
crb2a crumbs homolog 2a 0.019
msxc muscle segment homeobox C 0.019
nr1d2b nuclear receptor subfamily 1, group D, member 2b 0.019
dcc deleted in colorectal carcinoma 0.018
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Drosophila melanogaster
Name Description Probability Func Analog Organism
ey eyeless 0.835
dac dachshund 0.724
ato atonal 0.426
Dll Distal-less 0.343
ara araucan 0.325
toy twin of eyeless 0.320
Lim1 CG11354 gene product from transcript CG11354-RA 0.290
eyg eyegone 0.244
sens senseless 0.239
Poxn Pox neuro 0.235
sv shaven 0.222
pb proboscipedia 0.205
amos absent MD neurons and olfactory sensilla 0.190
lz lozenge 0.170
so sine oculis 0.165
E(spl) Enhancer of split 0.158
nub nubbin 0.148
Optix CG18455 gene product from transcript CG18455-RA 0.121
Eip93F CG18389 gene product from transcript CG18389-RB 0.103
AP-2 CG7807 gene product from transcript CG7807-RB 0.097
Dfd Deformed 0.092
danr distal antenna-related 0.085
oc ocelliless 0.082
tutl turtle 0.077
mira miranda 0.076
dan distal antenna 0.075
insc inscuteable 0.066
robo3 CG5423 gene product from transcript CG5423-RA 0.065
ro rough 0.063
ss spineless 0.062
klu klumpfuss 0.060
en engrailed 0.058
sca scabrous 0.056
sim single-minded 0.055
stan starry night 0.053
Tom Twin of m4 0.047
Ser Serrate 0.044
org-1 optomotor-blind-related-gene-1 0.043
caup caupolican 0.040
Awh Arrowhead 0.039
Uba2 Smt3 activating enzyme 2 0.035
disco disconnected 0.033
Ubx Ultrabithorax 0.033
B-H1 BarH1 0.031
al aristaless 0.029
lab labial 0.028
rn rotund 0.026
comm commissureless 0.025
Antp Antennapedia 0.023
ds dachsous 0.023
gsb gooseberry 0.023
zfh2 Zn finger homeodomain 2 0.022
dy dusky 0.022
argos CG4531 gene product from transcript CG4531-RA 0.021
ab abrupt 0.021
ik2 IkappaB kinase-like 2 0.020
Dip1 Dorsal interacting protein 1 0.020
y yellow 0.019
B-H2 BarH2 0.018
drl derailed 0.018
Zn72D CG5215 gene product from transcript CG5215-RB 0.018
eya eyes absent 0.018
ase asense 0.018
dsf dissatisfaction 0.018
HLHm7 E(spl) region transcript m7 0.018
phyl phyllopod 0.017
Doc2 Dorsocross2 0.016
CadN Cadherin-N 0.015
fj four-jointed 0.015
ptc patched 0.015
Snoo Sno oncogene 0.015
ac achaete 0.015
C15 CG7937 gene product from transcript CG7937-RA 0.015
vnd ventral nervous system defective 0.014
bi bifid 0.014
spdo sanpodo 0.014
Hs3st-B Heparan sulfate 3-O sulfotransferase-B 0.014
ct cut 0.014
m4 E(spl) region transcript m4 0.013
HLHmdelta E(spl) region transcript mdelta 0.013
gcm glial cells missing 0.013
malpha E(spl) region transcript malpha 0.013
pk prickle 0.013
bab2 CG9102 gene product from transcript CG9102-RA 0.013
nab CG33545 gene product from transcript CG33545-RC 0.012
Notum CG13076 gene product from transcript CG13076-RB 0.012
m6 E(spl) region transcript m6 0.012
Hr46 Hormone receptor-like in 46 0.012
CG32333 CG32333 gene product from transcript CG32333-RA 0.012
grim CG4345 gene product from transcript CG4345-RA 0.012
bab1 bric a brac 1 0.012
Rdl Resistant to dieldrin 0.011
svp seven up 0.011
vvl ventral veins lacking 0.011
iHog interference Hedgehog 0.011
Cam Calmodulin 0.011
salm spalt major 0.011
CG11093 CG11093 gene product from transcript CG11093-RB 0.011
HLHmbeta E(spl) region transcript mbeta 0.011
dve defective proventriculus 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Pax2 paired box gene 2 0.962
Otx2 orthodenticle homolog 2 (Drosophila) 0.903
Thra thyroid hormone receptor alpha 0.861
Crb2 crumbs homolog 2 (Drosophila) 0.855
Rho rhodopsin 0.773
Nr2e1 nuclear receptor subfamily 2, group E, member 1 0.759
Sox2 SRY-box containing gene 2 0.747
Duox2 dual oxidase 2 0.593
Pax6 paired box gene 6 0.585
Atxn1 ataxin 1 0.489
Tbx5 T-box 5 0.479
Gucy2d guanylate cyclase 2d 0.455
Thrb thyroid hormone receptor beta 0.438
Reln reelin 0.436
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.419
Scn5a sodium channel, voltage-gated, type V, alpha 0.339
Neurod1 neurogenic differentiation 1 0.288
Trpm1 transient receptor potential cation channel, subfamily M, member 1 0.269
Pou4f2 POU domain, class 4, transcription factor 2 0.231
Lhx3 LIM homeobox protein 3 0.226
Pcp2 Purkinje cell protein 2 (L7) 0.215
Myo6 myosin VI 0.214
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.201
ND6 NADH dehydrogenase subunit 6 0.182
Crx cone-rod homeobox containing gene 0.182
Eya1 eyes absent 1 homolog (Drosophila) 0.175
Tyr tyrosinase 0.173
Gja5 gap junction protein, alpha 5 0.150
Tbx3 T-box 3 0.147
Pitx2 paired-like homeodomain transcription factor 2 0.143
Pex5l peroxisomal biogenesis factor 5-like 0.143
Emx2 empty spiracles homolog 2 (Drosophila) 0.136
Dlx5 distal-less homeobox 5 0.125
Rbp3 retinol binding protein 3, interstitial 0.120
Gucy2e guanylate cyclase 2e 0.112
Igl immunoglobulin lambda chain complex 0.106
Emx1 empty spiracles homolog 1 (Drosophila) 0.100
Pten phosphatase and tensin homolog 0.092
Ghr growth hormone receptor 0.092
Tshz1 teashirt zinc finger family member 1 0.091
Insm1 insulinoma-associated 1 0.087
Cbl Casitas B-lineage lymphoma 0.083
Otx1 orthodenticle homolog 1 (Drosophila) 0.081
Kcnc1 potassium voltage gated channel, Shaw-related subfamily, member 1 0.080
Aipl1 aryl hydrocarbon receptor-interacting protein-like 1 0.074
Drd2 dopamine receptor D2 0.071
Rax retina and anterior neural fold homeobox 0.068
Lhx1 LIM homeobox protein 1 0.067
Zeb1 zinc finger E-box binding homeobox 1 0.066
Isl1 ISL1 transcription factor, LIM/homeodomain 0.066
Prph2 peripherin 2 0.064
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.064
Opn1mw opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan) 0.062
Rorb RAR-related orphan receptor beta 0.062
Cplx4 complexin 4 0.061
Tshr thyroid stimulating hormone receptor 0.059
Hcn1 hyperpolarization-activated, cyclic nucleotide-gated K+ 1 0.055
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.051
AI118078 expressed sequence AI118078 0.050
Cacna2d4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 0.048
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.047
Lepr leptin receptor 0.047
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.046
Gnb3 guanine nucleotide binding protein (G protein), beta 3 0.046
Opn1sw opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) 0.045
BC027072 cDNA sequence BC027072 0.044
Rap2c RAP2C, member of RAS oncogene family 0.044
Cacna1f calcium channel, voltage-dependent, alpha 1F subunit 0.043
Vsx2 visual system homeobox 2 0.041
Tbx10 T-box 10 0.041
Gata3 GATA binding protein 3 0.041
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.041
Pdc phosducin 0.040
Gdf5 growth differentiation factor 5 0.040
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.038
Mab21l2 mab-21-like 2 (C. elegans) 0.038
Neurod4 neurogenic differentiation 4 0.037
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.037
Abca4 ATP-binding cassette, sub-family A (ABC1), member 4 0.037
Ptf1a pancreas specific transcription factor, 1a 0.036
Rac1 RAS-related C3 botulinum substrate 1 0.036
Pax8 paired box gene 8 0.036
Ppard peroxisome proliferator activator receptor delta 0.035
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.034
Atoh7 atonal homolog 7 (Drosophila) 0.034
Pde6h phosphodiesterase 6H, cGMP-specific, cone, gamma 0.032
Cbln1 cerebellin 1 precursor protein 0.031
Rgs7 regulator of G protein signaling 7 0.030
Chd7 chromodomain helicase DNA binding protein 7 0.030
Tulp1 tubby like protein 1 0.030
Cav1 caveolin 1, caveolae protein 0.029
Tgfb1 transforming growth factor, beta 1 0.029
Guca1b guanylate cyclase activator 1B 0.029
Rarb retinoic acid receptor, beta 0.029
Shh sonic hedgehog 0.029
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.028
Guca1a guanylate cyclase activator 1a (retina) 0.028
Gpd2 glycerol phosphate dehydrogenase 2, mitochondrial 0.028
Arr3 arrestin 3, retinal 0.028
Fto fat mass and obesity associated 0.027
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism