IMP
Process View
The network for 'negative regulation of sodium ion transmembrane transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of sodium ion transmembrane transport
Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport.
| Name | Description | Probability | Func Analog Organism |
|---|
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 1.000 | |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.998 | |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.984 | |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.983 | |
| SMAD4 | SMAD family member 4 | 0.982 | |
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.946 | |
| SMAD1 | SMAD family member 1 | 0.938 | |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.877 | |
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.805 | |
| RNF11 | ring finger protein 11 | 0.718 | |
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.702 | |
| SMAD5 | SMAD family member 5 | 0.683 | |
| ANKRD13A | ankyrin repeat domain 13A | 0.680 | |
| CXXC5 | CXXC finger protein 5 | 0.674 | |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.377 | |
| SNX9 | sorting nexin 9 | 0.364 | |
| EZR | ezrin | 0.345 | |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.302 | |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta | 0.300 | |
| SMAD3 | SMAD family member 3 | 0.197 | |
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.171 | |
| SMAD7 | SMAD family member 7 | 0.163 | |
| SMAD2 | SMAD family member 2 | 0.163 | |
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha | 0.136 | |
| RHOA | ras homolog gene family, member A | 0.134 | |
| TRAF4 | TNF receptor-associated factor 4 | 0.117 | |
| ING2 | inhibitor of growth family, member 2 | 0.111 | |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.093 | |
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.075 | |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.074 | |
| RNF168 | ring finger protein 168 | 0.070 | |
| SCNN1B | sodium channel, nonvoltage-gated 1, beta | 0.069 | |
| STAMBP | STAM binding protein | 0.057 | |
| ARRDC3 | arrestin domain containing 3 | 0.055 | |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.053 | |
| UBQLN2 | ubiquilin 2 | 0.047 | |
| SMAD6 | SMAD family member 6 | 0.043 | |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 0.043 | |
| CCDC127 | coiled-coil domain containing 127 | 0.040 | |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.039 | |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.039 | |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 | 0.030 | |
| GRIA4 | glutamate receptor, ionotrophic, AMPA 4 | 0.028 | |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) | 0.027 | |
| SKIL | SKI-like oncogene | 0.026 | |
| MTMR4 | myotubularin related protein 4 | 0.025 | |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.025 | |
| PDZK1 | PDZ domain containing 1 | 0.023 | |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.022 | |
| SOX7 | SRY (sex determining region Y)-box 7 | 0.019 | |
| MYO6 | myosin VI | 0.019 | |
| SLC9A3R2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.018 | |
| EPAS1 | endothelial PAS domain protein 1 | 0.017 | |
| POU5F1 | POU class 5 homeobox 1 | 0.017 | |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) | 0.017 | |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.016 | |
| PHF20L1 | PHD finger protein 20-like 1 | 0.015 | |
| SGK3 | serum/glucocorticoid regulated kinase family, member 3 | 0.014 | |
| GATAD2B | GATA zinc finger domain containing 2B | 0.014 | |
| YY1 | YY1 transcription factor | 0.014 | |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 | 0.013 | |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.013 | |
| DOCK9 | dedicator of cytokinesis 9 | 0.012 | |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.012 | |
| DEDD | death effector domain containing | 0.012 | |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.012 | |
| ERCC6 | excision repair cross-complementing rodent repair deficiency, complementation group 6 | 0.012 | |
| MKL2 | MKL/myocardin-like 2 | 0.011 | |
| CSNK1D | casein kinase 1, delta | 0.011 | |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.011 | |
| OPTN | optineurin | 0.011 | |
| SRI | sorcin | 0.011 | |
| DTX1 | deltex homolog 1 (Drosophila) | 0.011 | |
| YAP1 | Yes-associated protein 1 | 0.010 | |
| GMEB1 | glucocorticoid modulatory element binding protein 1 | 0.010 | |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.010 | |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.010 | |
| DLG4 | discs, large homolog 4 (Drosophila) | 0.010 | |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.010 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Slc34a1 | solute carrier family 34 (sodium phosphate), member 1 | 1.000 | |
| Ywhab | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.897 | |
| Slc17a1 | solute carrier family 17 (sodium phosphate), member 1 | 0.366 | |
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.254 | |
| Flt1 | FMS-like tyrosine kinase 1 | 0.133 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.107 | |
| Ramp2 | receptor (calcitonin) activity modifying protein 2 | 0.095 | |
| Bspry | B-box and SPRY domain containing | 0.090 | |
| Pdzk1 | PDZ domain containing 1 | 0.089 | |
| Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.083 | |
| Vamp2 | vesicle-associated membrane protein 2 | 0.081 | |
| Pdzd3 | PDZ domain containing 3 | 0.056 | |
| Cuedc1 | CUE domain containing 1 | 0.056 | |
| Slc27a1 | solute carrier family 27 (fatty acid transporter), member 1 | 0.049 | |
| Epas1 | endothelial PAS domain protein 1 | 0.045 | |
| BC020535 | cDNA sequence BC020535 | 0.043 | |
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.039 | |
| Fxyd1 | FXYD domain-containing ion transport regulator 1 | 0.038 | |
| Sox18 | SRY-box containing gene 18 | 0.033 | |
| Plin4 | perilipin 4 | 0.033 | |
| Tenc1 | tensin like C1 domain-containing phosphatase | 0.032 | |
| Mapt | microtubule-associated protein tau | 0.032 | |
| Cftr | cystic fibrosis transmembrane conductance regulator homolog | 0.029 | |
| Mtap2 | microtubule-associated protein 2 | 0.027 | |
| Slc9a3r2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.026 | |
| Kcnk3 | potassium channel, subfamily K, member 3 | 0.026 | |
| Casr | calcium-sensing receptor | 0.025 | |
| Prdx6 | peroxiredoxin 6 | 0.024 | |
| Lamb2 | laminin, beta 2 | 0.023 | |
| Rasip1 | Ras interacting protein 1 | 0.023 | |
| Tef | thyrotroph embryonic factor | 0.023 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.022 | |
| Pdgfb | platelet derived growth factor, B polypeptide | 0.022 | |
| Arap3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | 0.022 | |
| Acvrl1 | activin A receptor, type II-like 1 | 0.021 | |
| Cldn5 | claudin 5 | 0.021 | |
| Pygm | muscle glycogen phosphorylase | 0.021 | |
| Kdr | kinase insert domain protein receptor | 0.020 | |
| Sox17 | SRY-box containing gene 17 | 0.020 | |
| Rab17 | RAB17, member RAS oncogene family | 0.020 | |
| Robo4 | roundabout homolog 4 (Drosophila) | 0.019 | |
| Slc9a3r1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.019 | |
| Esam | endothelial cell-specific adhesion molecule | 0.019 | |
| Nfic | nuclear factor I/C | 0.019 | |
| Atp1b2 | ATPase, Na+/K+ transporting, beta 2 polypeptide | 0.019 | |
| Card10 | caspase recruitment domain family, member 10 | 0.019 | |
| Kank3 | KN motif and ankyrin repeat domains 3 | 0.018 | |
| Jup | junction plakoglobin | 0.017 | |
| Cdh4 | cadherin 4 | 0.017 | |
| Egfl7 | EGF-like domain 7 | 0.017 | |
| Fhl2 | four and a half LIM domains 2 | 0.017 | |
| Sparcl1 | SPARC-like 1 | 0.017 | |
| Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.016 | |
| Sox13 | SRY-box containing gene 13 | 0.015 | |
| Flii | flightless I homolog (Drosophila) | 0.015 | |
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.015 | |
| Mep1a | meprin 1 alpha | 0.014 | |
| Shank3 | SH3/ankyrin domain gene 3 | 0.014 | |
| Zfp651 | zinc finger protein 651 | 0.014 | |
| Plp1 | proteolipid protein (myelin) 1 | 0.014 | |
| Cdh5 | cadherin 5 | 0.014 | |
| Limch1 | LIM and calponin homology domains 1 | 0.013 | |
| Caskin2 | CASK-interacting protein 2 | 0.013 | |
| Aspdh | aspartate dehydrogenase domain containing | 0.013 | |
| Ppara | peroxisome proliferator activated receptor alpha | 0.013 | |
| Ltbp4 | latent transforming growth factor beta binding protein 4 | 0.012 | |
| Tnxb | tenascin XB | 0.012 | |
| Sema3b | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.012 | |
| Slc34a3 | solute carrier family 34 (sodium phosphate), member 3 | 0.012 | |
| Slc22a1 | solute carrier family 22 (organic cation transporter), member 1 | 0.012 | |
| Cyp2d26 | cytochrome P450, family 2, subfamily d, polypeptide 26 | 0.012 | |
| Tek | endothelial-specific receptor tyrosine kinase | 0.012 | |
| Ushbp1 | Usher syndrome 1C binding protein 1 | 0.011 | |
| Hnf4a | hepatic nuclear factor 4, alpha | 0.011 | |
| Cdh13 | cadherin 13 | 0.011 | |
| Dnajb5 | DnaJ (Hsp40) homolog, subfamily B, member 5 | 0.011 | |
| Eng | endoglin | 0.011 | |
| Col4a3 | collagen, type IV, alpha 3 | 0.011 | |
| Proc | protein C | 0.011 | |
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.011 | |
| Kcnb1 | potassium voltage gated channel, Shab-related subfamily, member 1 | 0.010 | |
| Fgf13 | fibroblast growth factor 13 | 0.010 |