IMP
Process View
The network for 'sterol import' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
sterol import
The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
| Name | Description | Probability | Func Analog Organism |
|---|
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Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.799 | |
| ALB | albumin | 0.660 | |
| HP | haptoglobin | 0.621 | |
| APOA1 | apolipoprotein A-I | 0.153 | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.140 | |
| RRAGC | Ras-related GTP binding C | 0.100 | |
| APOC1 | apolipoprotein C-I | 0.089 | |
| LAMTOR2 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 | 0.064 | |
| A2M | alpha-2-macroglobulin | 0.050 | |
| APOC3 | apolipoprotein C-III | 0.046 | |
| C7orf59 | chromosome 7 open reading frame 59 | 0.043 | |
| NCF2 | neutrophil cytosolic factor 2 | 0.043 | |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.030 | |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | 0.027 | |
| FGA | fibrinogen alpha chain | 0.022 | |
| APOC2 | apolipoprotein C-II | 0.020 | |
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.018 | |
| WASL | Wiskott-Aldrich syndrome-like | 0.018 | |
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.017 | |
| AHSG | alpha-2-HS-glycoprotein | 0.016 | |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | 0.015 | |
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.014 | |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 | 0.014 | |
| BAIAP2 | BAI1-associated protein 2 | 0.014 | |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.013 | |
| PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.013 | |
| LRRK2 | leucine-rich repeat kinase 2 | 0.012 | |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.012 | |
| PLTP | phospholipid transfer protein | 0.012 | |
| RRAGA | Ras-related GTP binding A | 0.011 | |
| APOA2 | apolipoprotein A-II | 0.011 | |
| TRIP10 | thyroid hormone receptor interactor 10 | 0.010 |
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Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Dab1 | disabled homolog 1 (Drosophila) | 0.971 | |
| Apoe | apolipoprotein E | 0.937 | |
| Rac1 | RAS-related C3 botulinum substrate 1 | 0.266 | |
| Flt1 | FMS-like tyrosine kinase 1 | 0.153 | |
| Scd1 | stearoyl-Coenzyme A desaturase 1 | 0.137 | |
| Cav1 | caveolin 1, caveolae protein | 0.083 | |
| Lrp8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.056 | |
| Ldlr | low density lipoprotein receptor | 0.055 | |
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.053 | |
| Soat1 | sterol O-acyltransferase 1 | 0.049 | |
| Sqle | squalene epoxidase | 0.048 | |
| Vldlr | very low density lipoprotein receptor | 0.046 | |
| Reln | reelin | 0.045 | |
| Agtr1a | angiotensin II receptor, type 1a | 0.044 | |
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.042 | |
| Lss | lanosterol synthase | 0.038 | |
| Il1r1 | interleukin 1 receptor, type I | 0.033 | |
| Apoa4 | apolipoprotein A-IV | 0.031 | |
| Efemp2 | epidermal growth factor-containing fibulin-like extracellular matrix protein 2 | 0.031 | |
| Apob | apolipoprotein B | 0.031 | |
| Mtap1b | microtubule-associated protein 1B | 0.031 | |
| Npc1 | Niemann Pick type C1 | 0.029 | |
| Lox | lysyl oxidase | 0.028 | |
| Lcat | lecithin cholesterol acyltransferase | 0.028 | |
| Slc12a6 | solute carrier family 12, member 6 | 0.027 | |
| Ppp3r1 | protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) | 0.026 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.025 | |
| Lpin1 | lipin 1 | 0.025 | |
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.025 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.024 | |
| Cd47 | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) | 0.024 | |
| Ghr | growth hormone receptor | 0.023 | |
| Gjb2 | gap junction protein, beta 2 | 0.022 | |
| Hsd11b1 | hydroxysteroid 11-beta dehydrogenase 1 | 0.022 | |
| Aldob | aldolase B, fructose-bisphosphate | 0.022 | |
| Apoa2 | apolipoprotein A-II | 0.021 | |
| Dhcr24 | 24-dehydrocholesterol reductase | 0.021 | |
| Rragc | Ras-related GTP binding C | 0.020 | |
| Abhd5 | abhydrolase domain containing 5 | 0.019 | |
| Ahsg | alpha-2-HS-glycoprotein | 0.018 | |
| Hpx | hemopexin | 0.018 | |
| Fabp4 | fatty acid binding protein 4, adipocyte | 0.018 | |
| Cyp51 | cytochrome P450, family 51 | 0.018 | |
| Gba | glucosidase, beta, acid | 0.017 | |
| Crkl | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.017 | |
| Kcnma1 | potassium large conductance calcium-activated channel, subfamily M, alpha member 1 | 0.017 | |
| Slc2a4 | solute carrier family 2 (facilitated glucose transporter), member 4 | 0.016 | |
| Man2a1 | mannosidase 2, alpha 1 | 0.016 | |
| Fgb | fibrinogen beta chain | 0.015 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.015 | |
| Tlr2 | toll-like receptor 2 | 0.015 | |
| Ttr | transthyretin | 0.015 | |
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.015 | |
| Dhcr7 | 7-dehydrocholesterol reductase | 0.014 | |
| Gns | glucosamine (N-acetyl)-6-sulfatase | 0.014 | |
| Kcnj10 | potassium inwardly-rectifying channel, subfamily J, member 10 | 0.014 | |
| Mvd | mevalonate (diphospho) decarboxylase | 0.014 | |
| Stard4 | StAR-related lipid transfer (START) domain containing 4 | 0.014 | |
| Hsd17b7 | hydroxysteroid (17-beta) dehydrogenase 7 | 0.014 | |
| Timp3 | tissue inhibitor of metalloproteinase 3 | 0.013 | |
| Elovl4 | elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4 | 0.013 | |
| Tgfbr1 | transforming growth factor, beta receptor I | 0.013 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.013 | |
| Agtr2 | angiotensin II receptor, type 2 | 0.012 | |
| Rnf111 | ring finger 111 | 0.012 | |
| Klf15 | Kruppel-like factor 15 | 0.012 | |
| Sc5d | sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae) | 0.012 | |
| Apom | apolipoprotein M | 0.012 | |
| Elavl4 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) | 0.011 | |
| Pkia | protein kinase inhibitor, alpha | 0.011 | |
| Cdc42se1 | CDC42 small effector 1 | 0.011 | |
| Arhgef7 | Rho guanine nucleotide exchange factor (GEF7) | 0.011 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.011 | |
| Adamts1 | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 | 0.011 | |
| Sptlc2 | serine palmitoyltransferase, long chain base subunit 2 | 0.010 | |
| Aacs | acetoacetyl-CoA synthetase | 0.010 | |
| Bpnt1 | bisphosphate 3'-nucleotidase 1 | 0.010 |