IMP
Process View
The network for 'general adaptation syndrome' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
general adaptation syndrome
General adaptation syndrome is the set of changes in various organ systems of the body, especially the pituitary-endocrine system, in response to a wide range of strong external stimuli, both physiological and psychological. It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses.
| Name | Description | Probability | Func Analog Organism |
|---|
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Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Fosb | FBJ osteosarcoma oncogene B | 0.281 | |
| Fos | FBJ osteosarcoma oncogene | 0.227 | |
| Jun | Jun oncogene | 0.201 | |
| Egr1 | early growth response 1 | 0.195 | |
| Gabrq | gamma-aminobutyric acid (GABA) A receptor, subunit theta | 0.195 | |
| Dusp1 | dual specificity phosphatase 1 | 0.192 | |
| Cd247 | CD247 antigen | 0.170 | |
| Gpr27 | G protein-coupled receptor 27 | 0.126 | |
| Ikzf4 | IKAROS family zinc finger 4 | 0.123 | |
| Mmp24 | matrix metallopeptidase 24 | 0.085 | |
| Btg2 | B-cell translocation gene 2, anti-proliferative | 0.078 | |
| Wnt2b | wingless related MMTV integration site 2b | 0.077 | |
| Atf3 | activating transcription factor 3 | 0.067 | |
| Cux2 | cut-like homeobox 2 | 0.064 | |
| Ppyr1 | pancreatic polypeptide receptor 1 | 0.062 | |
| Lhb | luteinizing hormone beta | 0.061 | |
| Rhbdf1 | rhomboid family 1 (Drosophila) | 0.061 | |
| Mc5r | melanocortin 5 receptor | 0.055 | |
| Kcnb1 | potassium voltage gated channel, Shab-related subfamily, member 1 | 0.053 | |
| Htr6 | 5-hydroxytryptamine (serotonin) receptor 6 | 0.051 | |
| Cckbr | cholecystokinin B receptor | 0.048 | |
| Rtbdn | retbindin | 0.044 | |
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.044 | |
| Junb | Jun-B oncogene | 0.042 | |
| Klk4 | kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) | 0.041 | |
| Kcnh1 | potassium voltage-gated channel, subfamily H (eag-related), member 1 | 0.041 | |
| Nr4a2 | nuclear receptor subfamily 4, group A, member 2 | 0.041 | |
| Cacng5 | calcium channel, voltage-dependent, gamma subunit 5 | 0.039 | |
| Foxf1a | forkhead box F1a | 0.038 | |
| Kcnk4 | potassium channel, subfamily K, member 4 | 0.037 | |
| Smyd1 | SET and MYND domain containing 1 | 0.037 | |
| Npy5r | neuropeptide Y receptor Y5 | 0.037 | |
| Cyr61 | cysteine rich protein 61 | 0.036 | |
| Kcna6 | potassium voltage-gated channel, shaker-related, subfamily, member 6 | 0.033 | |
| Adra2a | adrenergic receptor, alpha 2a | 0.033 | |
| Prkcc | protein kinase C, gamma | 0.033 | |
| Shc3 | src homology 2 domain-containing transforming protein C3 | 0.032 | |
| Thrb | thyroid hormone receptor beta | 0.032 | |
| Tnni2 | troponin I, skeletal, fast 2 | 0.032 | |
| Drd2 | dopamine receptor D2 | 0.032 | |
| Kcnj12 | potassium inwardly-rectifying channel, subfamily J, member 12 | 0.031 | |
| Nog | noggin | 0.031 | |
| Matn1 | matrilin 1, cartilage matrix protein | 0.030 | |
| Angpt1 | angiopoietin 1 | 0.029 | |
| Adm | adrenomedullin | 0.029 | |
| Sntb1 | syntrophin, basic 1 | 0.028 | |
| Zfp787 | zinc finger protein 787 | 0.027 | |
| Mchr1 | melanin-concentrating hormone receptor 1 | 0.027 | |
| Zfp36 | zinc finger protein 36 | 0.027 | |
| Pthlh | parathyroid hormone-like peptide | 0.026 | |
| Th | tyrosine hydroxylase | 0.026 | |
| Slc16a8 | solute carrier family 16 (monocarboxylic acid transporters), member 8 | 0.026 | |
| Plcb1 | phospholipase C, beta 1 | 0.026 | |
| Rorb | RAR-related orphan receptor beta | 0.026 | |
| Kcnd1 | potassium voltage-gated channel, Shal-related family, member 1 | 0.026 | |
| Tacr1 | tachykinin receptor 1 | 0.026 | |
| Tek | endothelial-specific receptor tyrosine kinase | 0.026 | |
| Rgs9 | regulator of G-protein signaling 9 | 0.025 | |
| Csrnp1 | cysteine-serine-rich nuclear protein 1 | 0.025 | |
| Gsx1 | GS homeobox 1 | 0.025 | |
| Wnt10b | wingless related MMTV integration site 10b | 0.025 | |
| Chrm1 | cholinergic receptor, muscarinic 1, CNS | 0.025 | |
| Adora2a | adenosine A2a receptor | 0.024 | |
| Kcna2 | potassium voltage-gated channel, shaker-related subfamily, member 2 | 0.024 | |
| Tac2 | tachykinin 2 | 0.024 | |
| Kcnj4 | potassium inwardly-rectifying channel, subfamily J, member 4 | 0.023 | |
| Htr7 | 5-hydroxytryptamine (serotonin) receptor 7 | 0.023 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.023 | |
| Des | desmin | 0.023 | |
| Fosl2 | fos-like antigen 2 | 0.023 | |
| Gpr3 | G-protein coupled receptor 3 | 0.022 | |
| Tgfa | transforming growth factor alpha | 0.022 | |
| Htr2c | 5-hydroxytryptamine (serotonin) receptor 2C | 0.022 | |
| Cbln1 | cerebellin 1 precursor protein | 0.022 | |
| Nhedc2 | Na+/H+ exchanger domain containing 2 | 0.022 | |
| Klf4 | Kruppel-like factor 4 (gut) | 0.022 | |
| Crhr1 | corticotropin releasing hormone receptor 1 | 0.022 | |
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.022 | |
| Cacna1a | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.022 | |
| Fxyd7 | FXYD domain-containing ion transport regulator 7 | 0.021 | |
| Htr1b | 5-hydroxytryptamine (serotonin) receptor 1B | 0.021 | |
| Spry4 | sprouty homolog 4 (Drosophila) | 0.021 | |
| Treml1 | triggering receptor expressed on myeloid cells-like 1 | 0.021 | |
| Fam163b | family with sequence similarity 163, member B | 0.021 | |
| Nrg3 | neuregulin 3 | 0.021 | |
| Adcy8 | adenylate cyclase 8 | 0.021 | |
| Mybpc3 | myosin binding protein C, cardiac | 0.020 | |
| Fgf16 | fibroblast growth factor 16 | 0.020 | |
| Esrrb | estrogen related receptor, beta | 0.020 | |
| Adrb1 | adrenergic receptor, beta 1 | 0.020 | |
| Avp | arginine vasopressin | 0.019 | |
| Tgfbr3 | transforming growth factor, beta receptor III | 0.019 | |
| Ier2 | immediate early response 2 | 0.019 | |
| Lepr | leptin receptor | 0.019 | |
| Rtn4r | reticulon 4 receptor | 0.019 | |
| St8sia5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 | 0.019 | |
| Cox4i2 | cytochrome c oxidase subunit IV isoform 2 | 0.019 | |
| Vipr2 | vasoactive intestinal peptide receptor 2 | 0.019 | |
| Pcdh12 | protocadherin 12 | 0.018 | |
| Npas2 | neuronal PAS domain protein 2 | 0.018 |