The network for 'small molecule metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

small molecule metabolic process

The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.

Name Description Probability Func Analog Organism
sem-5 Protein SEM-5 0.482
pkg-1 Protein PKG-1 0.438
F53F10.2 Protein F53F10.2 0.428
egl-15 Protein EGL-15 0.398
got-1.2 Protein GOT-1.2 0.386
ant-1.1 Protein ANT-1.1 0.384
hsp-1 Protein HSP-1 0.377
nhr-45 Protein NHR-45 0.366
lin-5 Protein LIN-5 0.328
lin-2 Protein LIN-2 0.323
atp-2 Protein ATP-2 0.316
pdl-1 Protein PDL-1 0.309
ucr-1 Protein UCR-1 0.298
pmt-1 Protein PMT-1 0.292
gst-13 Protein GST-13 0.269
apl-1 Protein APL-1 0.264
elo-1 Protein ELO-1 0.264
sma-6 Protein SMA-6 0.253
CELE_T05B11.1 Protein T05B11.1 0.250
got-2.2 Protein GOT-2.2 0.250
CELE_F59C6.5 Protein F59C6.5 0.250
lag-1 Protein LAG-1 0.248
ZK370.8 Protein ZK370.8 0.248
har-1 Protein HAR-1 0.247
itr-1 Protein ITR-1 0.246
klp-15 Protein KLP-15 0.243
flh-2 Protein FLH-2 0.241
CELE_C12D8.1 Protein C12D8.1 0.239
mei-1 Protein MEI-1 0.237
CELE_T01B11.2 Protein T01B11.2 0.233
atp-5 Protein ATP-5 0.233
tars-1 Protein TARS-1 0.228
egl-44 Protein EGL-44 0.226
CELE_M05D6.5 Protein M05D6.5 0.224
etr-1 Protein ETR-1 0.224
eat-16 Protein EAT-16 0.219
goa-1 Protein GOA-1 0.218
egl-18 Protein EGL-18 0.218
patr-1 Protein PATR-1 0.217
plc-1 Protein PLC-1 0.215
sams-4 Protein SAMS-4 0.214
ina-1 Protein INA-1 0.213
dpyd-1 Protein DPYD-1 0.210
ahcy-1 Protein AHCY-1 0.209
unc-23 Protein UNC-23 0.208
F01G4.6 Protein F01G4.6 0.205
hsp-70 Protein HSP-70 0.203
sams-3 Protein SAMS-3 0.202
cts-1 Protein CTS-1 0.202
glp-1 Protein GLP-1 0.199
vab-3 Protein VAB-3 0.197
iff-2 Protein IFF-2 0.197
sto-4 Protein STO-4 0.197
mel-11 Protein MEL-11 0.197
lin-7 Protein LIN-7 0.197
fat-4 Protein FAT-4 0.194
gars-1 Protein GARS-1 0.194
R07H5.8 Protein R07H5.8 0.193
ugt-22 Protein UGT-22 0.192
tag-320 Protein TAG-320 0.192
sur-5 Protein SUR-5 0.191
hmg-5 Protein HMG-5 0.189
sup-17 Protein SUP-17 0.187
ZK484.1 Protein ZK484.1 0.186
tax-6 Protein TAX-6 0.185
F58F12.1 Protein F58F12.1 0.185
inx-8 Protein INX-8 0.184
gei-18 Protein GEI-18 0.183
spd-2 Protein SPD-2 0.182
zfp-1 Protein ZFP-1 0.182
pha-4 Protein PHA-4 0.182
elo-2 Protein ELO-2 0.181
pptr-2 Protein PPTR-2 0.181
plc-3 Protein PLC-3 0.180
egl-13 Protein EGL-13 0.180
icl-1 Protein ICL-1 0.180
sdhb-1 Protein SDHB-1 0.180
CELE_F27D4.1 Protein F27D4.1 0.179
cku-70 Protein CKU-70 0.178
unc-45 Protein UNC-45 0.177
C39D10.7 Protein C39D10.7 0.176
F48A11.4 Protein F48A11.4 0.176
ace-1 Protein ACE-1 0.176
D1081.8 Protein D1081.8 0.175
gdh-1 Protein GDH-1 0.175
cyp-35C1 Protein CYP-35C1 0.175
F17A9.4 Protein F17A9.4 0.174
cyc-1 Protein CYC-1 0.173
acp-6 Protein ACP-6 0.173
alh-3 Protein ALH-3 0.172
C35B1.5 Protein C35B1.5 0.172
hsp-16.2 Protein HSP-16.2 0.171
CELE_D1054.8 Protein D1054.8 0.170
rfp-1 Protein RFP-1 0.170
pxf-1 Protein PXF-1 0.170
unc-57 Protein UNC-57 0.170
acox-1 Protein ACOX-1 0.169
alh-4 Protein ALH-4 0.166
atg-18 Protein ATG-18 0.166
vpr-1 Protein VPR-1 0.165
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Danio rerio
Name Description Probability Func Analog Organism
pwp2h PWP2 periodic tryptophan protein homolog (yeast) 0.696
gpia glucose phosphate isomerase a 0.685
mao monoamine oxidase 0.658
pparg peroxisome proliferator activated receptor gamma 0.607
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.604
pcna proliferating cell nuclear antigen 0.601
ache acetylcholinesterase 0.601
got2b glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2) 0.588
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.555
tal1 T-cell acute lymphocytic leukemia 1 0.538
atp1b3b ATPase, Na+/K+ transporting, beta 3b polypeptide 0.532
acta1b actin, alpha 1b, skeletal muscle 0.528
acox1 acyl-Coenzyme A oxidase 1, palmitoyl 0.513
apoeb apolipoprotein Eb 0.510
aox3 aldehyde oxidase 3 0.503
aldocb aldolase C, fructose-bisphosphate, b 0.500
otpa orthopedia homolog a 0.491
oxtl oxytocin-like 0.480
sox9b SRY-box containing gene 9b 0.477
pax8 paired box gene 8 0.468
adra2a adrenergic, alpha-2A-, receptor 0.466
pdhb pyruvate dehydrogenase (lipoamide) beta 0.461
sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.456
hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.446
gata6 GATA-binding protein 6 0.443
kal1a Kallmann syndrome 1a sequence 0.443
hs6st2 heparan sulfate 6-O-sulfotransferase 2 0.442
robo3 roundabout homolog 3 0.436
hs6st1a heparan sulfate 6-O-sulfotransferase 1a 0.433
mtp microsomal triglyceride transfer protein 0.429
fzd7b frizzled homolog 7b 0.425
gnat2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.417
cyp3a65 cytochrome P450, family 3, subfamily A, polypeptide 65 0.413
apoa4 apolipoprotein A-IV 0.411
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.410
idh1 isocitrate dehydrogenase 1 (NADP+), soluble 0.402
lef1 lymphocyte enhancer binding factor 1 0.402
epas1b endothelial PAS domain protein 1b 0.402
drd2b dopamine receptor D2b 0.400
rag2 recombination activating gene 2 0.398
ckbb creatine kinase, brain b 0.394
tars threonyl-tRNA synthetase 0.390
LOC799612 prolactin 2 0.386
gclc glutamate-cysteine ligase, catalytic subunit 0.385
psen1 presenilin 1 0.382
si:ch211-209p5.2 si:ch211-209p5.2 0.382
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.379
uqcrc1 ubiquinol-cytochrome c reductase core protein I 0.378
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.376
fgfr3 fibroblast growth factor receptor 3 0.373
ttna titin a 0.370
rho rhodopsin 0.367
tgif1 TGFB-induced factor homeobox 1 0.361
rag1 recombination activating gene 1 0.360
ncor1 nuclear receptor co-repressor 1 0.359
bida BH3 interacting domain death agonist 0.349
zgc:158138 zgc:158138 0.348
acsl4a acyl-CoA synthetase long-chain family member 4a 0.346
jag1b jagged 1b 0.343
ptgs2a prostaglandin-endoperoxide synthase 2a 0.342
cx43 connexin 43 0.339
kita kit receptor a 0.334
elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.325
gc3 guanylyl cyclase 3 0.321
ptgesl prostaglandin E synthase 2-like 0.320
dnmt4 DNA (cytosine-5-)-methyltransferase 4 0.319
rxrab retinoid x receptor, alpha b 0.319
slc4a2b solute carrier family 4, anion exchanger, member 2b 0.319
klf4 Kruppel-like factor 4 0.317
aldh8a1 aldehyde dehydrogenase 8 family, member A1 0.315
nrp2b neuropilin 2b 0.314
cbr1l carbonyl reductase 1-like 0.313
dlx5a distal-less homeobox gene 5a 0.312
zbtb4 zinc finger and BTB domain containing 4 0.307
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.306
mga MAX gene associated 0.302
aldh9a1a aldehyde dehydrogenase 9 family, member A1a 0.300
hspd1 heat shock 60kD protein 1 (chaperonin) 0.299
mdh1a malate dehydrogenase 1a, NAD (soluble) 0.298
pah phenylalanine hydroxylase 0.294
aldh7a1 aldehyde dehydrogenase 7 family, member A1 0.292
sox11b SRY-box containing gene 11b 0.290
atp2b1a ATPase, Ca++ transporting, plasma membrane 1a 0.288
dldh dihydrolipoamide dehydrogenase 0.286
uqcrc2b ubiquinol-cytochrome c reductase core protein IIb 0.285
dpyd dihydropyrimidine dehydrogenase 0.285
hccs holocytochrome c synthase 0.285
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.284
ndufa8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8 0.277
si:dkey-228g21.4 si:dkey-228g21.4 0.276
efnb2a ephrin B2a 0.273
zgc:111961 zgc:111961 0.273
ucp1 uncoupling protein 1 0.272
bdnf brain-derived neurotrophic factor 0.271
nr1i2 nuclear receptor subfamily 1, group I, member 2 0.270
bms1l BMS1-like, ribosome assembly protein (yeast) 0.267
pax7a paired box gene 7a 0.267
gria2b glutamate receptor, ionotropic, AMPA 2b 0.266
gadd45bb growth arrest and DNA-damage-inducible, beta b 0.265
hadha hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit 0.264
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.996
GstE6 Glutathione S transferase E6 0.954
Rac1 CG2248 gene product from transcript CG2248-RA 0.930
tkv thickveins 0.925
ik2 IkappaB kinase-like 2 0.890
ATPsyn-gamma ATP synthase-gamma chain 0.878
drk downstream of receptor kinase 0.870
Ced-12 CG5336 gene product from transcript CG5336-RA 0.857
eIF-4E Eukaryotic initiation factor 4E 0.847
shi shibire 0.846
Rho1 CG8416 gene product from transcript CG8416-RB 0.845
Tsc1 CG6147 gene product from transcript CG6147-RA 0.844
Idh Isocitrate dehydrogenase 0.829
mbc myoblast city 0.825
Cortactin CG3637 gene product from transcript CG3637-RA 0.820
Cam Calmodulin 0.801
gro groucho 0.774
rols rolling pebbles 0.755
Rheb CG1081 gene product from transcript CG1081-RA 0.751
Mad Mothers against dpp 0.732
porin CG6647 gene product from transcript CG6647-RA 0.719
CG7920 CG7920 gene product from transcript CG7920-RA 0.713
Plc21C Phospholipase C at 21C 0.709
Got2 Glutamate oxaloacetate transaminase 2 0.708
bsk basket 0.676
Pk61C Protein kinase 61C 0.669
CG6543 CG6543 gene product from transcript CG6543-RA 0.667
E(z) Enhancer of zeste 0.667
rl rolled 0.662
bs blistered 0.660
sgl sugarless 0.659
Argk Arginine kinase 0.649
Egfr Epidermal growth factor receptor 0.646
dos daughter of sevenless 0.645
unc-104 CG8566 gene product from transcript CG8566-RB 0.644
Pka-C1 cAMP-dependent protein kinase 1 0.636
ttk tramtrack 0.636
dm diminutive 0.629
Tpi Triose phosphate isomerase 0.629
loco locomotion defects 0.627
wit wishful thinking 0.615
Vps35 Vacuolar protein sorting 35 0.613
Eno Enolase 0.612
Tctp Translationally controlled tumor protein 0.609
Mer Merlin 0.604
InR Insulin-like receptor 0.603
Rac2 CG8556 gene product from transcript CG8556-RA 0.595
Fatp Fatty acid (long chain) transport protein 0.587
EfTuM Elongation factor Tu mitochondrial 0.585
Khc Kinesin heavy chain 0.583
N Notch 0.583
cno canoe 0.577
zip zipper 0.565
shot short stop 0.561
CG2064 CG2064 gene product from transcript CG2064-RA 0.552
Ada2b CG9638 gene product from transcript CG9638-RA 0.551
TER94 CG2331 gene product from transcript CG2331-RA 0.545
SNF1A SNF1A/AMP-activated protein kinase 0.541
rap retina aberrant in pattern 0.538
Pten CG5671 gene product from transcript CG5671-RB 0.535
l(2)03709 lethal (2) 03709 0.535
pbl pebble 0.533
blw bellwether 0.532
Hs6st Heparan sulfate 6-O-sulfotransferase 0.527
sxc super sex combs 0.526
Jafrac1 thioredoxin peroxidase 1 0.525
hth homothorax 0.524
Mmp1 Matrix metalloproteinase 1 0.519
Adh Alcohol dehydrogenase 0.519
dys dysfusion 0.513
CG11876 CG11876 gene product from transcript CG11876-RA 0.505
alpha-Est7 alpha-Esterase-7 0.505
rhea CG6831 gene product from transcript CG6831-RA 0.500
rpr reaper 0.499
CG8155 CG8155 gene product from transcript CG8155-RA 0.499
tub tube 0.497
Pak PAK-kinase 0.496
stai stathmin 0.495
Ino80 CG31212 gene product from transcript CG31212-RA 0.492
par-6 CG5884 gene product from transcript CG5884-RA 0.483
geminin CG3183 gene product from transcript CG3183-RA 0.477
Cctgamma CG8977 gene product from transcript CG8977-RC 0.473
Caki Calcium/calmodulin-dependent protein kinase 0.472
CG8036 CG8036 gene product from transcript CG8036-RB 0.471
Sod Superoxide dismutase 0.469
Hn Henna 0.460
dco discs overgrown 0.459
srp serpent 0.458
rictor rapamycin-insensitive companion of Tor 0.457
toc toucan 0.455
Xbp1 X box binding protein-1 0.454
Vha68-2 CG3762 gene product from transcript CG3762-RA 0.453
Ugt35a UDP-glycosyltransferase 35a 0.451
G-oalpha47A G protein oalpha 47A 0.450
Rab2 Rab-protein 2 0.449
LanA Laminin A 0.448
Arf79F ADP ribosylation factor 79F 0.448
PyK Pyruvate kinase 0.446
GstD4 Glutathione S transferase D4 0.445
Atg1 Autophagy-specific gene 1 0.445
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism