The network for 'positive regulation of cell death' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cell death

Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.

Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.177
F36G3.1 Protein F36G3.1 0.100
egl-46 Protein EGL-46 0.093
ceh-44 Protein CEH-44 0.090
let-19 Protein LET-19 0.071
bar-1 Protein BAR-1 0.066
hsp-1 Protein HSP-1 0.066
rpl-7 Protein RPL-7 0.065
cam-1 Protein CAM-1 0.065
par-5 Protein PAR-5 0.061
inx-3 Protein INX-3 0.058
act-3 Protein ACT-3 0.053
cst-2 Protein CST-2 0.053
pdfr-1 Protein PDFR-1 0.048
ceh-20 Protein CEH-20 0.046
sem-5 Protein SEM-5 0.046
ZK484.1 Protein ZK484.1 0.045
pat-12 Protein PAT-12 0.045
gpb-2 Protein GPB-2 0.039
dys-1 Protein DYS-1 0.039
vha-17 Protein VHA-17 0.038
clic-1 Protein CLIC-1 0.037
tufm-1 Protein TUFM-1 0.037
vha-8 Protein VHA-8 0.035
zyg-11 Protein ZYG-11 0.035
R90.1 Protein R90.1 0.033
let-60 Protein LET-60 0.033
rme-4 Protein RME-4 0.031
mel-11 Protein MEL-11 0.031
prp-21 Protein PRP-21 0.031
atn-1 Protein ATN-1 0.031
inx-13 Protein INX-13 0.030
pry-1 Protein PRY-1 0.030
glp-1 Protein GLP-1 0.029
atp-2 Protein ATP-2 0.029
flt-1 Protein FLT-1 0.029
rab-5 Protein RAB-5 0.029
fbxa-150 Protein FBXA-150 0.029
arrd-13 Protein ARRD-13 0.029
eat-6 Protein EAT-6 0.029
itsn-1 Protein ITSN-1 0.028
sgt-1 Protein SGT-1 0.028
fbxc-36 Protein FBXC-36 0.028
eor-2 Protein EOR-2 0.027
dyb-1 Protein DYB-1 0.027
K10D6.4 Protein K10D6.4 0.027
gap-2 Protein GAP-2 0.027
ten-1 Protein TEN-1 0.027
fem-1 Protein FEM-1 0.026
hpo-34 Protein HPO-34 0.026
fkh-2 Protein FKH-2 0.026
lmn-1 Protein LMN-1 0.025
F21A10.2 Protein F21A10.2 0.025
eya-1 Protein EYA-1 0.025
vab-1 Protein VAB-1 0.025
cpt-1 Protein CPT-1 0.025
gmeb-1 Protein GMEB-1 0.025
egl-1 Protein EGL-1 0.024
gpb-1 Protein GPB-1 0.024
nud-2 Protein NUD-2 0.024
vha-1 Protein VHA-1 0.024
inf-1 Protein INF-1 0.024
vab-3 Protein VAB-3 0.024
tir-1 Protein TIR-1 0.024
oxi-1 Protein OXI-1 0.024
gex-3 Protein GEX-3 0.023
CELE_C18C4.5 Protein C18C4.5 0.023
stam-1 Protein STAM-1 0.023
hcp-3 Protein HCP-3 0.023
CELE_C01G12.3 Protein C01G12.3 0.023
elks-1 Protein ELKS-1 0.023
pmk-1 Protein PMK-1 0.023
T28C6.7 Protein T28C6.7 0.023
act-5 Protein ACT-5 0.023
sma-6 Protein SMA-6 0.023
dsh-2 Protein DSH-2 0.022
hum-6 Protein HUM-6 0.022
ahcy-1 Protein AHCY-1 0.022
daf-11 Protein DAF-11 0.021
ina-1 Protein INA-1 0.021
F36A2.13 Protein F36A2.13 0.021
CELE_F54F7.6 Protein F54F7.6 0.021
rhi-1 Protein RHI-1 0.021
rpl-18 Protein RPL-18 0.021
cnd-1 Protein CND-1 0.021
uaf-1 Protein UAF-1 0.021
hum-5 Protein HUM-5 0.021
brp-1 Protein BRP-1 0.020
trap-4 Protein TRAP-4 0.020
unc-73 Protein UNC-73 0.020
acs-4 Protein ACS-4 0.020
cts-1 Protein CTS-1 0.020
zyg-1 Protein ZYG-1 0.020
sta-1 Protein STA-1 0.020
CELE_R06A4.2 Protein R06A4.2 0.020
ung-1 Protein UNG-1 0.020
nhr-2 Protein NHR-2 0.020
hmr-1 Protein HMR-1 0.020
smf-2 Protein SMF-2 0.019
cnp-3 Protein CNP-3 0.019
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Danio rerio
Name Description Probability Func Analog Organism
bbc3 BCL2 binding component 3 0.786
mcl1a myeloid cell leukemia sequence 1a 0.691
robo3 roundabout homolog 3 0.640
bmp2b bone morphogenetic protein 2b 0.614
itgb1b.2 integrin, beta 1b.2 0.605
bcl2l1 bcl2-like 1 0.545
evx1 even-skipped homeobox 1 0.499
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.496
fgf8a fibroblast growth factor 8 a 0.470
fos v-fos FBJ murine osteosarcoma viral oncogene homolog 0.466
tp53 tumor protein p53 0.441
cmyb transcription factor cmyb 0.435
socs3a suppressor of cytokine signaling 3a 0.402
egr1 early growth response 1 0.370
tbx1 T-box 1 0.352
adipor1b adiponectin receptor 1b 0.309
jun jun proto-oncogene 0.292
baxa bcl2-associated X protein, a 0.281
ptger2a prostaglandin E receptor 2a (subtype EP2) 0.266
bad BCL2-antagonist of cell death 0.245
junb jun B proto-oncogene 0.245
tcf12 transcription factor 12 0.232
bcl2l10 BCL2-like 10 (apoptosis facilitator) 0.203
mmp2 matrix metalloproteinase 2 0.198
alcama activated leukocyte cell adhesion molecule a 0.194
ptpra protein tyrosine phosphatase, receptor type, A 0.187
gadd45ba growth arrest and DNA-damage-inducible, beta a 0.185
atp6v1ba ATPase, H+ transporting, lysosomal, V1 subunit B, member a 0.184
th tyrosine hydroxylase 0.180
fgfr1a fibroblast growth factor receptor 1a 0.180
znf503 zinc finger protein 503 0.177
epas1b endothelial PAS domain protein 1b 0.175
cav1 caveolin 1 0.174
bida BH3 interacting domain death agonist 0.163
krt4 keratin 4 0.159
adrb2a adrenergic receptor, beta 2a 0.151
junbl jun B proto-oncogene, like 0.149
fn1 fibronectin 1 0.148
nfkbiaa nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a 0.148
socs1 suppressor of cytokine signaling 1 0.142
phlda2 pleckstrin homology-like domain, family A, member 2 0.137
evpl envoplakin 0.134
myca myelocytomatosis oncogene a 0.133
ahr2 aryl hydrocarbon receptor 2 0.132
ikzf1 IKAROS family zinc finger 1 (Ikaros) 0.125
per2 period homolog 2 (Drosophila) 0.124
stc1l stanniocalcin 1, like 0.124
tob1a transducer of ERBB2, 1a 0.123
inhbaa inhibin, beta Aa 0.122
mych myelocytomatosis oncogene homolog 0.122
bambia BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a 0.121
sept7b septin 7b 0.120
znf703 zinc finger protein 703 0.120
xbp1 X-box binding protein 1 0.119
btg1 B-cell translocation gene 1 0.119
cbfb core-binding factor, beta subunit 0.119
atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.117
clu clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) 0.116
btg2 B-cell translocation gene 2 0.111
gnb1b guanine nucleotide binding protein (G protein), beta polypeptide 1b 0.109
mpx myeloid-specific peroxidase 0.109
rpl7a ribosomal protein L7a 0.109
hoxa13a homeo box A13a 0.106
hif1ab hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b 0.106
csnk1da casein kinase 1, delta a 0.102
mibp2 muscle-specific beta 1 integrin binding protein 2 0.101
runx2b runt-related transcription factor 2b 0.100
ldb1a LIM-domain binding factor 1a 0.100
b2m beta-2-microglobulin 0.098
id1 inhibitor of DNA binding 1 0.095
pdlim1 PDZ and LIM domain 1 (elfin) 0.094
casp8 caspase 8, apoptosis-related cysteine peptidase 0.093
klf4a Kruppel-like transcription factor 4a 0.091
LOC559201 similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3) 0.091
hoxd4a homeo box D4a 0.089
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.089
atf3 activating transcription factor 3 0.086
tagln2 transgelin 2 0.085
col10a1 collagen, type X, alpha 1 0.082
ef1a elongation factor 1-alpha 0.081
cx43 connexin 43 0.080
plagl2 pleiomorphic adenoma gene-like 2 0.079
hoxa9b homeo box A9b 0.079
clock clock 0.077
hsp90a.2 heat shock protein 90-alpha 2 0.077
atp1b3b ATPase, Na+/K+ transporting, beta 3b polypeptide 0.076
ndr1 nodal-related 1 0.076
si:ch211-212m21.5 si:ch211-212m21.5 0.076
tph2 tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) 0.076
itgb1a integrin, beta 1a 0.075
itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.074
arl6ip1 ADP-ribosylation factor-like 6 interacting protein 1 0.074
notch1a notch homolog 1a 0.074
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.073
ncf1 neutrophil cytosolic factor 1 0.073
apoeb apolipoprotein Eb 0.072
negr1 neuronal growth regulator 1 0.072
nf1a neurofibromin 1a 0.071
irx5a iroquois homeobox protein 5a 0.071
msxc muscle segment homeobox C 0.070
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Drosophila melanogaster
Name Description Probability Func Analog Organism
wg wingless 0.893
nej nejire 0.838
hep hemipterous 0.805
Atg1 Autophagy-specific gene 1 0.760
rpr reaper 0.692
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.685
Dcp-1 Death caspase-1 0.678
Atpalpha Na pump alpha subunit 0.662
CG11347 CG11347 gene product from transcript CG11347-RE 0.651
ptc patched 0.611
Rac1 CG2248 gene product from transcript CG2248-RA 0.611
Egfr Epidermal growth factor receptor 0.608
slmb supernumerary limbs 0.587
gro groucho 0.550
Mad Mothers against dpp 0.526
sgg shaggy 0.524
Ras85D Ras oncogene at 85D 0.484
Akt1 CG4006 gene product from transcript CG4006-RA 0.469
debcl death executioner Bcl-2 homologue 0.395
sd scalloped 0.365
gig gigas 0.365
trio CG18214 gene product from transcript CG18214-RA 0.360
Fmr1 CG6203 gene product from transcript CG6203-RC 0.343
pyd polychaetoid 0.331
dm diminutive 0.323
Su(H) Suppressor of Hairless 0.314
InR Insulin-like receptor 0.308
Myb Myb oncogene-like 0.301
jar jaguar 0.286
CaMKII Calcium/calmodulin-dependent protein kinase II 0.282
egr eiger 0.269
wts warts 0.263
Rbf Retinoblastoma-family protein 0.256
th thread 0.253
drk downstream of receptor kinase 0.249
Eip74EF Ecdysone-induced protein 74EF 0.245
Rab5 Rab-protein 5 0.244
ed echinoid 0.241
tin tinman 0.233
scny scrawny 0.229
rok Rho-kinase 0.225
Atx2 Ataxin-2 0.222
bchs blue cheese 0.220
shn schnurri 0.220
caz cabeza 0.218
neur neuralized 0.216
milt milton 0.202
gek genghis khan 0.201
Notum CG13076 gene product from transcript CG13076-RB 0.200
p53 CG33336 gene product from transcript CG33336-RB 0.198
Hrb98DE Heterogeneous nuclear ribonucleoprotein at 98DE 0.197
car carnation 0.185
Sdc Syndecan 0.180
tim timeless 0.179
CG9772 CG9772 gene product from transcript CG9772-RB 0.174
key kenny 0.169
ci cubitus interruptus 0.168
crol crooked legs 0.166
Pten CG5671 gene product from transcript CG5671-RB 0.163
loqs loquacious 0.163
tsr twinstar 0.158
bif bifocal 0.157
gcm glial cells missing 0.156
Rac2 CG8556 gene product from transcript CG8556-RA 0.151
cathD CG1548 gene product from transcript CG1548-RA 0.151
rno rhinoceros 0.148
skd skuld 0.146
nkd naked cuticle 0.146
Ser Serrate 0.145
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.136
Adf1 Adh transcription factor 1 0.136
G-salpha60A G protein salpha 60A 0.135
emc extra macrochaetae 0.134
hh hedgehog 0.134
S6k RPS6-p70-protein kinase 0.133
CG5524 CG5524 gene product from transcript CG5524-RA 0.131
Moe Moesin 0.131
Caps Calcium activated protein for secretion 0.130
Trxr-1 Thioredoxin reductase-1 0.129
mid midline 0.129
Sce Sex combs extra 0.126
katanin-60 katanin 60 0.125
beta-Spec beta Spectrin 0.125
X11L CG5675 gene product from transcript CG5675-RB 0.123
lap like-AP180 0.121
Adar Adenosine deaminase acting on RNA 0.121
TBPH CG10327 gene product from transcript CG10327-RC 0.121
robo roundabout 0.121
RASSF8 CG5053 gene product from transcript CG5053-RA 0.119
CadN Cadherin-N 0.118
Trf2 TATA box binding protein-related factor 2 0.117
yki yorkie 0.114
trpml transient receptor potential mucolipin 0.112
unc-13 CG2999 gene product from transcript CG2999-RA 0.111
CRMP Collapsin Response Mediator Protein 0.110
CG10984 CG10984 gene product from transcript CG10984-RC 0.109
SAK Sak kinase 0.109
alpha-Adaptin CG4260 gene product from transcript CG4260-RA 0.109
LanA Laminin A 0.107
hiw highwire 0.107
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Homo sapiens
Name Description Probability Func Analog Organism
TP53 tumor protein p53 1.000
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.000
BCL2 B-cell CLL/lymphoma 2 1.000
CREBBP CREB binding protein 1.000
MDM2 Mdm2 p53 binding protein homolog (mouse) 1.000
EGFR epidermal growth factor receptor 0.999
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.999
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.999
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.999
AR androgen receptor 0.998
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.997
RB1 retinoblastoma 1 0.995
BCL2L1 BCL2-like 1 0.995
XIAP X-linked inhibitor of apoptosis 0.995
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.992
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.992
FHL2 four and a half LIM domains 2 0.990
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.989
CAV1 caveolin 1, caveolae protein, 22kDa 0.988
FAS Fas (TNF receptor superfamily, member 6) 0.988
SMAD3 SMAD family member 3 0.986
JUN jun proto-oncogene 0.983
HIPK2 homeodomain interacting protein kinase 2 0.983
UBC ubiquitin C 0.980
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.974
MAPK14 mitogen-activated protein kinase 14 0.973
APP amyloid beta (A4) precursor protein 0.970
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.966
FN1 fibronectin 1 0.963
DAXX death-domain associated protein 0.962
TRAF2 TNF receptor-associated factor 2 0.959
SMAD1 SMAD family member 1 0.955
ESR1 estrogen receptor 1 0.945
SMAD7 SMAD family member 7 0.945
BIRC3 baculoviral IAP repeat containing 3 0.937
FADD Fas (TNFRSF6)-associated via death domain 0.934
EP300 E1A binding protein p300 0.934
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.923
BAD BCL2-associated agonist of cell death 0.909
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.906
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.904
HDAC2 histone deacetylase 2 0.895
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.879
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.867
BID BH3 interacting domain death agonist 0.865
SMAD2 SMAD family member 2 0.858
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.856
STAT1 signal transducer and activator of transcription 1, 91kDa 0.853
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.851
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.849
CFLAR CASP8 and FADD-like apoptosis regulator 0.845
BAX BCL2-associated X protein 0.845
TRADD TNFRSF1A-associated via death domain 0.845
THBS1 thrombospondin 1 0.842
LRRK2 leucine-rich repeat kinase 2 0.841
BRCA1 breast cancer 1, early onset 0.839
STK3 serine/threonine kinase 3 0.839
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.827
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.826
SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.823
CCR5 chemokine (C-C motif) receptor 5 0.819
ANXA1 annexin A1 0.818
CUL1 cullin 1 0.814
HMGB1 high mobility group box 1 0.809
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.805
C1QA complement component 1, q subcomponent, A chain 0.801
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.799
SQSTM1 sequestosome 1 0.799
SP1 Sp1 transcription factor 0.791
TRAF1 TNF receptor-associated factor 1 0.781
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.779
NCOR2 nuclear receptor corepressor 2 0.777
APC adenomatous polyposis coli 0.772
CTGF connective tissue growth factor 0.772
GADD45A growth arrest and DNA-damage-inducible, alpha 0.766
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.766
TUBA1A tubulin, alpha 1a 0.764
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.763
E2F1 E2F transcription factor 1 0.743
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.741
HBB hemoglobin, beta 0.740
RPL11 ribosomal protein L11 0.734
CDK4 cyclin-dependent kinase 4 0.728
MAPK1 mitogen-activated protein kinase 1 0.725
CXCL9 chemokine (C-X-C motif) ligand 9 0.714
CCND1 cyclin D1 0.714
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.711
RIPK2 receptor-interacting serine-threonine kinase 2 0.709
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.707
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.704
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.704
HNF4A hepatocyte nuclear factor 4, alpha 0.701
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.698
NCOA3 nuclear receptor coactivator 3 0.698
CCL5 chemokine (C-C motif) ligand 5 0.697
HTT huntingtin 0.687
CCL4 chemokine (C-C motif) ligand 4 0.686
MAPT microtubule-associated protein tau 0.682
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.680
TNF tumor necrosis factor 0.674
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Mus musculus
Name Description Probability Func Analog Organism
Tnf tumor necrosis factor 0.999
Pten phosphatase and tensin homolog 0.998
Ctnnb1 catenin (cadherin associated protein), beta 1 0.995
Rarg retinoic acid receptor, gamma 0.989
Rxra retinoid X receptor alpha 0.988
Bcl2 B-cell leukemia/lymphoma 2 0.985
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.984
Gli3 GLI-Kruppel family member GLI3 0.983
Otx2 orthodenticle homolog 2 (Drosophila) 0.983
Gli2 GLI-Kruppel family member GLI2 0.982
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.981
Igh immunoglobulin heavy chain complex 0.979
Apc adenomatosis polyposis coli 0.977
Fgfr2 fibroblast growth factor receptor 2 0.972
Ptgs2 prostaglandin-endoperoxide synthase 2 0.965
Trp53 transformation related protein 53 0.965
Nos3 nitric oxide synthase 3, endothelial cell 0.947
Ren1 renin 1 structural 0.943
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.940
Lyz2 lysozyme 2 0.938
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.935
Tgfb1 transforming growth factor, beta 1 0.934
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.926
Mcl1 myeloid cell leukemia sequence 1 0.923
Mapk14 mitogen-activated protein kinase 14 0.918
Pax2 paired box gene 2 0.915
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.915
Ptch1 patched homolog 1 0.908
Fas Fas (TNF receptor superfamily member 6) 0.907
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.905
Vegfa vascular endothelial growth factor A 0.899
En1 engrailed 1 0.896
Fgfr1 fibroblast growth factor receptor 1 0.887
Skil SKI-like 0.883
Cd44 CD44 antigen 0.882
Nos2 nitric oxide synthase 2, inducible 0.880
Foxc1 forkhead box C1 0.858
Shh sonic hedgehog 0.858
Csf1 colony stimulating factor 1 (macrophage) 0.847
Mmp9 matrix metallopeptidase 9 0.839
Axin1 axin 1 0.829
Ikbkg inhibitor of kappaB kinase gamma 0.829
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.828
Nf1 neurofibromatosis 1 0.810
Tgfb2 transforming growth factor, beta 2 0.806
Klf6 Kruppel-like factor 6 0.805
Sfrp2 secreted frizzled-related protein 2 0.805
Foxc2 forkhead box C2 0.803
Socs1 suppressor of cytokine signaling 1 0.791
Msx2 homeobox, msh-like 2 0.789
Acvr1 activin A receptor, type 1 0.776
Ret ret proto-oncogene 0.776
Zeb1 zinc finger E-box binding homeobox 1 0.761
Ncoa3 nuclear receptor coactivator 3 0.757
Cd19 CD19 antigen 0.753
Zfp36 zinc finger protein 36 0.752
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.745
Casp8 caspase 8 0.744
Spnb2 spectrin beta 2 0.740
Id1 inhibitor of DNA binding 1 0.739
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.739
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.737
Fos FBJ osteosarcoma oncogene 0.736
Egr1 early growth response 1 0.734
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.726
Jun Jun oncogene 0.715
Smad3 MAD homolog 3 (Drosophila) 0.702
Gdnf glial cell line derived neurotrophic factor 0.697
Rara retinoic acid receptor, alpha 0.694
Ntf3 neurotrophin 3 0.693
Notch1 Notch gene homolog 1 (Drosophila) 0.686
Bax BCL2-associated X protein 0.685
Cd40 CD40 antigen 0.680
Socs3 suppressor of cytokine signaling 3 0.678
Rarb retinoic acid receptor, beta 0.671
Sin3a transcriptional regulator, SIN3A (yeast) 0.670
Braf Braf transforming gene 0.664
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.664
Bmp7 bone morphogenetic protein 7 0.663
Sox9 SRY-box containing gene 9 0.663
Bmp4 bone morphogenetic protein 4 0.662
Anxa3 annexin A3 0.657
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.642
Lef1 lymphoid enhancer binding factor 1 0.638
Gja1 gap junction protein, alpha 1 0.636
Tcf4 transcription factor 4 0.634
Thbs1 thrombospondin 1 0.629
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.623
Dok1 docking protein 1 0.615
Il6st interleukin 6 signal transducer 0.608
Wt1 Wilms tumor 1 homolog 0.607
Bcl6 B-cell leukemia/lymphoma 6 0.603
Fst follistatin 0.601
Runx2 runt related transcription factor 2 0.597
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.592
Atm ataxia telangiectasia mutated homolog (human) 0.590
Cycs cytochrome c, somatic 0.586
Dusp1 dual specificity phosphatase 1 0.586
Prrx1 paired related homeobox 1 0.584
Mdm4 transformed mouse 3T3 cell double minute 4 0.582
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Rattus norvegicus
Name Description Probability Func Analog Organism
Egr1 early growth response 1 0.771
Btg2 BTG family, member 2 0.658
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.604
Anxa4 annexin A4 0.589
Fos FBJ osteosarcoma oncogene 0.514
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.501
S100a8 S100 calcium binding protein A8 0.437
Gzmk granzyme K 0.414
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.408
Slit3 slit homolog 3 (Drosophila) 0.405
Ccl4 chemokine (C-C motif) ligand 4 0.391
Jak2 Janus kinase 2 0.381
Asna1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 0.377
Pspn persephin 0.350
Prkcg protein kinase C, gamma 0.343
Anxa5 annexin A5 0.343
Klf4 Kruppel-like factor 4 (gut) 0.339
Anxa2 annexin A2 0.336
Gna15 guanine nucleotide binding protein, alpha 15 0.333
Mrgprf MAS-related GPR, member F 0.331
LOC305103 cell surface glycoprotein gp42 0.328
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.325
Arpc1b actin related protein 2/3 complex, subunit 1B 0.323
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.318
S100a9 S100 calcium binding protein A9 0.315
Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor 0.310
Sycn syncollin 0.310
Ppp1ca protein phosphatase 1, catalytic subunit, alpha isoform 0.301
Rap1b RAP1B, member of RAS oncogene family 0.297
Egr3 early growth response 3 0.292
Pnlip pancreatic lipase 0.291
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.289
Cd247 Cd247 molecule 0.289
Agtr1a angiotensin II receptor, type 1a 0.288
Selp selectin P 0.288
Tlr7 toll-like receptor 7 0.286
Stat6 signal transducer and activator of transcription 6 0.281
Hspa1a heat shock 70kD protein 1A 0.278
Ptafr platelet-activating factor receptor 0.274
Phlda1 pleckstrin homology-like domain, family A, member 1 0.271
Pgk1 phosphoglycerate kinase 1 0.270
Itgam integrin, alpha M 0.267
Ptprc protein tyrosine phosphatase, receptor type, C 0.267
Prap1 proline-rich acidic protein 1 0.262
Egr2 early growth response 2 0.259
Gucy2d guanylate cyclase 2d 0.258
Gria2 glutamate receptor, ionotropic, AMPA 2 0.251
Cd44 Cd44 molecule 0.249
Casp3 caspase 3 0.243
Junb jun B proto-oncogene 0.237
Cd86 CD86 molecule 0.235
Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.234
Casp1 caspase 1 0.233
Fosl1 fos-like antigen 1 0.232
Anxa1 annexin A1 0.231
S100a10 S100 calcium binding protein A10 0.230
Adarb2 adenosine deaminase, RNA-specific, B2 0.227
Hck hemopoietic cell kinase 0.224
Ptch1 patched homolog 1 (Drosophila) 0.220
Stc1 stanniocalcin 1 0.218
Trim47 tripartite motif-containing 47 0.217
Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 0.215
Muc4 mucin 4, cell surface associated 0.214
Faslg Fas ligand (TNF superfamily, member 6) 0.210
Eln elastin 0.209
Vim vimentin 0.207
Flt1 FMS-related tyrosine kinase 1 0.205
Vip vasoactive intestinal peptide 0.205
Tlr4 toll-like receptor 4 0.203
Capn8 calpain 8 0.202
Cd38 CD38 molecule 0.199
Serpinb6a serine (or cysteine) peptidase inhibitor, clade B, member 6a 0.199
Zfp36 zinc finger protein 36 0.198
Tmod3 tropomodulin 3 0.198
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.196
Sst somatostatin 0.195
Hr hairless 0.193
Zfp36l1 zinc finger protein 36, C3H type-like 1 0.193
Cpb1 carboxypeptidase B1 (tissue) 0.192
Kcna6 potassium voltage gated channel, shaker related subfamily, member 6 0.192
Ripk3 receptor-interacting serine-threonine kinase 3 0.190
Cxcl10 chemokine (C-X-C motif) ligand 10 0.190
Ccnl1 cyclin L1 0.189
Matk megakaryocyte-associated tyrosine kinase 0.189
Lepr leptin receptor 0.186
Il2rb interleukin 2 receptor, beta 0.185
Dlx5 distal-less homeobox 5 0.185
Svs1 seminal vesicle secretory protein 1 0.184
Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.184
Rims1 regulating synaptic membrane exocytosis 1 0.181
Ocln occludin 0.180
Ccl5 chemokine (C-C motif) ligand 5 0.180
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.180
Cd4 Cd4 molecule 0.179
Arhgap4 Rho GTPase activating protein 4 0.178
Cd14 CD14 molecule 0.178
Ccnd3 cyclin D3 0.178
Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A 0.177
Vcan versican 0.177
Cd80 Cd80 molecule 0.173
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
EAF1 Eaf1p 0.104
HOG1 Hog1p 0.085
DNM1 Dnm1p 0.080
DCS2 Dcs2p 0.063
EPL1 Epl1p 0.063
LTV1 Ltv1p 0.062
NBP2 Nbp2p 0.059
SEC62 Sec62p 0.056
CPR1 Cpr1p 0.055
GUT2 Gut2p 0.053
DIA2 Dia2p 0.052
PSP2 Psp2p 0.052
CDC34 Cdc34p 0.051
SMP1 Smp1p 0.048
PMT3 Pmt3p 0.047
CDC53 Cdc53p 0.047
SKP1 Skp1p 0.046
MCD4 Mcd4p 0.046
IKI1 Iki1p 0.046
RAD16 Rad16p 0.046
SEC63 Sec63p 0.045
MSK1 Msk1p 0.044
QCR6 Qcr6p 0.044
RPS5 Rps5p 0.044
HSL1 Hsl1p 0.044
EAF7 Eaf7p 0.043
THO2 Tho2p 0.043
ALD6 Ald6p 0.042
LHS1 Lhs1p 0.042
NDE1 Nde1p 0.041
STI1 Sti1p 0.041
PTP2 Ptp2p 0.040
RIP1 Rip1p 0.040
UFO1 Ufo1p 0.040
MDM34 Mdm34p 0.039
OCH1 Och1p 0.039
CCP1 Ccp1p 0.038
MAS1 Mas1p 0.038
BDH1 Bdh1p 0.037
VMA13 Vma13p 0.037
UPS3 Ups3p 0.037
SLT2 Slt2p 0.037
YPL088W hypothetical protein 0.036
SRP54 Srp54p 0.036
YLR257W hypothetical protein 0.036
HOS4 Hos4p 0.036
STE7 Ste7p 0.036
LAG2 Lag2p 0.036
CMK1 Cmk1p 0.036
EAF3 Eaf3p 0.035
HUG1 Hug1p 0.035
CYT1 Cyt1p 0.035
HYP2 Hyp2p 0.035
PBP1 Pbp1p 0.035
IZH3 Izh3p 0.034
SGE1 Sge1p 0.034
WTM2 Wtm2p 0.034
NAP1 Nap1p 0.034
PET9 Pet9p 0.034
HDA2 Hda2p 0.034
SGT1 Sgt1p 0.034
OLA1 Ola1p 0.034
AKL1 Akl1p 0.034
HAL5 Hal5p 0.033
QCR7 Qcr7p 0.033
SNT1 Snt1p 0.033
ATG18 Atg18p 0.033
SIL1 Sil1p 0.033
CKA1 Cka1p 0.032
MSP1 Msp1p 0.032
HSP60 Hsp60p 0.032
ERO1 Ero1p 0.032
ACS2 Acs2p 0.032
SUI1 Sui1p 0.032
MMT2 Mmt2p 0.032
AHP1 Ahp1p 0.032
UBP9 Ubp9p 0.031
TGL4 Tgl4p 0.031
YBR085C-A hypothetical protein 0.031
PCH2 Pch2p 0.031
TEF2 Tef2p 0.031
ZWF1 Zwf1p 0.031
PRK1 Prk1p 0.031
HOR7 Hor7p 0.031
PBS2 Pbs2p 0.030
SLX9 Slx9p 0.030
HOT1 Hot1p 0.030
YAP1802 hypothetical protein 0.030
CCW12 Ccw12p 0.030
EXG2 Exg2p 0.030
YJR085C hypothetical protein 0.030
ECM30 Ecm30p 0.030
COX15 Cox15p 0.030
TEF1 Tef1p 0.029
RPL10 Rpl10p 0.029
SUT1 Sut1p 0.029
NPL4 Npl4p 0.029
RAD55 Rad55p 0.029
SSA4 Ssa4p 0.029
BIT61 Bit61p 0.029