The network for 'protein localization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

protein localization

Any process in which a protein is transported to, or maintained in, a specific location.

Caenorhabditis elegans
Name Description Probability Func Analog Organism
sas-4 Protein SAS-4 0.845
osm-5 Protein OSM-5 0.730
egl-18 Protein EGL-18 0.710
sem-5 Protein SEM-5 0.662
pha-4 Protein PHA-4 0.599
pas-2 Protein PAS-2 0.537
che-13 Protein CHE-13 0.503
par-5 Protein PAR-5 0.500
zyg-8 Protein ZYG-8 0.450
daf-19 Protein DAF-19 0.446
unc-83 Protein UNC-83 0.421
flh-1 Protein FLH-1 0.419
D1081.8 Protein D1081.8 0.417
egl-8 Protein EGL-8 0.403
rab-5 Protein RAB-5 0.400
glp-1 Protein GLP-1 0.395
goa-1 Protein GOA-1 0.378
osm-6 Protein OSM-6 0.370
vab-3 Protein VAB-3 0.347
imb-2 Protein IMB-2 0.343
npp-19 Protein NPP-19 0.319
elt-6 Protein ELT-6 0.317
pdl-1 Protein PDL-1 0.316
dsh-2 Protein DSH-2 0.315
dcr-1 Protein DCR-1 0.306
spc-1 Protein SPC-1 0.304
apr-1 Protein APR-1 0.300
npp-7 Protein NPP-7 0.294
ina-1 Protein INA-1 0.288
klp-7 Protein KLP-7 0.287
arl-13 Protein ARL-13 0.287
W04D2.6 Protein W04D2.6 0.280
nphp-4 Protein NPHP-4 0.274
mpk-1 Protein MPK-1 0.265
egl-44 Protein EGL-44 0.265
mtm-1 Protein MTM-1 0.260
akt-1 Protein AKT-1 0.251
hlh-1 Protein HLH-1 0.246
let-607 Protein LET-607 0.242
che-2 Protein CHE-2 0.241
sma-9 Protein SMA-9 0.240
spr-5 Protein SPR-5 0.236
ftt-2 Protein FTT-2 0.232
mig-15 Protein MIG-15 0.229
daf-3 Protein DAF-3 0.226
vha-1 Protein VHA-1 0.224
ran-4 Protein RAN-4 0.222
knl-1 Protein KNL-1 0.218
dpff-1 Protein DPFF-1 0.217
egl-30 Protein EGL-30 0.217
unc-10 Protein UNC-10 0.215
cdc-42 Protein CDC-42 0.214
jbts-14 Protein JBTS-14 0.210
unc-9 Protein UNC-9 0.209
baf-1 Protein BAF-1 0.208
egl-13 Protein EGL-13 0.206
F59E12.9 Protein F59E12.9 0.204
calu-1 Protein CALU-1 0.204
hcp-1 Protein HCP-1 0.201
hsp-1 Protein HSP-1 0.201
spdl-1 Protein SPDL-1 0.201
gei-17 Protein GEI-17 0.200
sma-1 Protein SMA-1 0.200
dnj-10 Protein DNJ-10 0.199
cul-2 Protein CUL-2 0.197
sad-1 Protein SAD-1 0.196
rpt-3 Protein RPT-3 0.195
sqv-4 Protein SQV-4 0.194
unc-6 Protein UNC-6 0.194
pry-1 Protein PRY-1 0.192
ada-2 Protein ADA-2 0.191
hcp-4 Protein HCP-4 0.189
F52G3.1 Protein F52G3.1 0.189
CELE_C25A1.12 Protein C25A1.12 0.189
eps-8 Protein EPS-8 0.188
sago-2 Protein SAGO-2 0.187
ubq-1 Protein UBQ-1 0.187
sar-1 Protein SAR-1 0.186
CELE_F47G4.4 Protein F47G4.4 0.185
T27A3.2 Protein T27A3.2 0.184
csnk-1 Protein CSNK-1 0.181
unc-73 Protein UNC-73 0.181
par-3 Protein PAR-3 0.181
dpf-3 Protein DPF-3 0.181
hsr-9 Protein HSR-9 0.180
mel-28 Protein MEL-28 0.180
T24H7.3 Protein T24H7.3 0.179
rol-3 Protein ROL-3 0.179
wdfy-2 Protein WDFY-2 0.178
Y71F9AL.9 Protein Y71F9AL.9 0.178
nphp-1 Protein NPHP-1 0.177
osm-3 Protein OSM-3 0.176
lin-23 Protein LIN-23 0.175
let-60 Protein LET-60 0.175
ajm-1 Protein AJM-1 0.175
mep-1 Protein MEP-1 0.174
unc-78 Protein UNC-78 0.174
eff-1 Protein EFF-1 0.174
chc-1 Protein CHC-1 0.173
egl-46 Protein EGL-46 0.172
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Danio rerio
Name Description Probability Func Analog Organism
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.799
pkd2 polycystic kidney disease 2 0.649
alcamb activated leukocyte cell adhesion molecule b 0.465
notch1a notch homolog 1a 0.405
eif3ha eukaryotic translation initiation factor 3, subunit H, a 0.353
egr1 early growth response 1 0.346
copa coatomer protein complex, subunit alpha 0.340
cdh1 cadherin 1, epithelial 0.322
rag1 recombination activating gene 1 0.307
igf1ra insulin-like growth factor 1a receptor 0.286
kif17 kinesin family member 17 0.271
twist1a twist1a 0.269
flot2a flotillin 2a 0.262
prkcz protein kinase C, zeta 0.255
gdf6a growth differentiation factor 6a 0.253
foxa2 forkhead box A2 0.252
crb2a crumbs homolog 2a 0.250
tp53 tumor protein p53 0.248
cxcr4b chemokine (C-X-C motif), receptor 4b 0.241
snai1a snail homolog 1a (Drosophila) 0.218
cav1 caveolin 1 0.203
musk muscle, skeletal, receptor tyrosine kinase 0.202
wnt10a wingless-type MMTV integration site family, member 10a 0.196
cltca clathrin, heavy polypeptide a (Hc) 0.185
slc4a4a solute carrier family 4, member 4a 0.183
robo2 roundabout homolog 2 0.177
bmp2b bone morphogenetic protein 2b 0.162
nanos3 nanos homolog 3 0.160
rab1a RAB1A, member RAS oncogene family 0.157
gpia glucose phosphate isomerase a 0.157
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.155
rarab retinoic acid receptor, alpha b 0.154
hnf1ba HNF1 homeobox Ba 0.153
flr fleer 0.152
ef1a elongation factor 1-alpha 0.147
pcna proliferating cell nuclear antigen 0.144
scrib scribbled homolog (Drosophila) 0.143
fgf10a fibroblast growth factor 10a 0.140
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.138
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.136
cnn2 calponin 2 0.128
lama2 laminin, alpha 2 0.126
tll1 tolloid-like 1 0.126
hhip hedgehog interacting protein 0.125
cntn1a contactin 1a 0.122
plcg1 phospholipase C, gamma 1 0.121
smad1 MAD homolog 1 (Drosophila) 0.120
lef1 lymphocyte enhancer binding factor 1 0.119
csnk1da casein kinase 1, delta a 0.118
ccnb1 cyclin B1 0.118
dlg1 discs, large (Drosophila) homolog 1 0.117
mmp2 matrix metalloproteinase 2 0.117
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.110
mib mind bomb 0.109
mtp microsomal triglyceride transfer protein 0.108
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.104
jup junction plakoglobin 0.100
lamb2 laminin, beta 2 (laminin S) 0.100
pak2a p21 (CDKN1A)-activated kinase 2a 0.099
fgf3 fibroblast growth factor 3 0.098
nf1a neurofibromin 1a 0.098
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.097
glra4b glycine receptor, alpha 4b 0.097
cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) 0.093
otud5a OTU domain containing 5a 0.093
mapk3 mitogen-activated protein kinase 3 0.091
wnt4a wingless-type MMTV integration site family, member 4a 0.090
dlg2 discs, large (Drosophila) homolog 2 0.089
runx2a runt-related transcription factor 2a 0.089
copb1 coatomer protein complex, subunit beta 1 0.089
mapk4 mitogen-activated protein kinase 4 0.088
sept2 septin 2 0.088
wls wntless homolog (Drosophila) 0.086
ptk2.1 protein tyrosine kinase 2a 0.084
rab11fip4a RAB11 family interacting protein 4 (class II) a 0.083
ssrp1a structure specific recognition protein 1a 0.083
cyfip2 cytoplasmic FMR1 interacting protein 2 0.082
cdh23 cadherin-like 23 0.081
fmr1 fragile X mental retardation 1 0.081
itgb1b.2 integrin, beta 1b.2 0.081
wnt2ba wingless-type MMTV integration site family, member 2Ba 0.081
ptmab prothymosin, alpha b 0.080
krt4 keratin 4 0.080
nkx2.2a NK2 transcription factor related 2a 0.080
gcm2 glial cells missing homolog 2 (Drosophila) 0.079
pomca proopiomelanocortin a 0.079
dag1 dystroglycan 1 0.078
btr12 bloodthirsty-related gene family, member 12 0.078
pwp2h PWP2 periodic tryptophan protein homolog (yeast) 0.077
mmp13a matrix metalloproteinase 13a 0.077
jun jun proto-oncogene 0.076
csrp1a cysteine and glycine-rich protein 1a 0.076
cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.075
myf5 myogenic factor 5 0.075
vcana versican a 0.075
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.074
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.074
bms1l BMS1-like, ribosome assembly protein (yeast) 0.074
casp3a caspase 3, apoptosis-related cysteine protease a 0.074
llgl2 lethal giant larvae homolog 2 (Drosophila) 0.074
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Mad Mothers against dpp 0.987
slmb supernumerary limbs 0.972
Rho1 CG8416 gene product from transcript CG8416-RB 0.952
Moe Moesin 0.923
raps rapsynoid 0.913
TER94 CG2331 gene product from transcript CG2331-RA 0.902
Stat92E Signal-transducer and activator of transcription protein at 92E 0.900
Rab11 Rab-protein 11 0.894
flw flapwing 0.893
baz bazooka 0.878
smt3 CG4494 gene product from transcript CG4494-RA 0.836
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.827
beta-Spec beta Spectrin 0.825
Myb Myb oncogene-like 0.813
shot short stop 0.809
wb wing blister 0.809
gig gigas 0.806
Mer Merlin 0.798
puc puckered 0.795
spas spastin 0.793
ci cubitus interruptus 0.793
eya eyes absent 0.787
bam bag of marbles 0.785
mys myospheroid 0.784
dos daughter of sevenless 0.783
spin spinster 0.777
klar klarsicht 0.769
Pten CG5671 gene product from transcript CG5671-RB 0.759
sqh spaghetti squash 0.753
ovo CG6824 gene product from transcript CG6824-RE 0.747
so sine oculis 0.745
insc inscuteable 0.743
cpb capping protein beta 0.741
dally division abnormally delayed 0.737
Lam Lamin 0.726
chic chickadee 0.725
Rac1 CG2248 gene product from transcript CG2248-RA 0.723
fog folded gastrulation 0.718
Syx7 Syntaxin 7 0.715
Khc Kinesin heavy chain 0.711
RanGap Ran GTPase activating protein 0.695
Atg8a Autophagy-specific gene 8a 0.676
hyd hyperplastic discs 0.668
Tsc1 CG6147 gene product from transcript CG6147-RA 0.664
lin19 lin-19-like 0.660
Src64B Src oncogene at 64B 0.644
LanB2 Laminin B2 0.643
rhea CG6831 gene product from transcript CG6831-RA 0.640
spi spitz 0.627
Jra Jun-related antigen 0.626
cpa capping protein alpha 0.626
LamC Lamin C 0.620
trc tricornered 0.616
aop anterior open 0.610
sina seven in absentia 0.609
l(2)gl lethal (2) giant larvae 0.607
Arp66B Actin-related protein 66B 0.605
Git CG16728 gene product from transcript CG16728-RA 0.602
BicD Bicaudal D 0.601
tum tumbleweed 0.598
eff effete 0.598
Lis-1 Lissencephaly-1 0.597
RASSF8 CG5053 gene product from transcript CG5053-RA 0.592
ninaE neither inactivation nor afterpotential E 0.589
pim pimples 0.588
dco discs overgrown 0.562
Dad Daughters against dpp 0.550
Rheb CG1081 gene product from transcript CG1081-RA 0.545
asp abnormal spindle 0.541
CtBP C-terminal Binding Protein 0.539
PP2A-B' CG7913 gene product from transcript CG7913-RK 0.539
wg wingless 0.539
Rab5 Rab-protein 5 0.538
nmo nemo 0.537
Nrx-IV Neurexin IV 0.533
Pp2A-29B Protein phosphatase 2A at 29B 0.530
Ras85D Ras oncogene at 85D 0.529
G-ialpha65A G protein alphai subunit 65A 0.519
nct nicastrin 0.516
Tab2 TAK1-associated binding protein 2 0.514
Uba1 Ubiquitin activating enzyme 1 0.511
gro groucho 0.508
ATP7 CG1886 gene product from transcript CG1886-RB 0.502
Tm1 Tropomyosin 1 0.500
nwk nervous wreck 0.497
ft fat 0.493
Rab7 Rab-protein 7 0.493
sd scalloped 0.483
GluRIIA Glutamate receptor IIA 0.482
Akt1 CG4006 gene product from transcript CG4006-RA 0.478
Tif-IA CG3278 gene product from transcript CG3278-RA 0.473
EndoGI Endonuclease G inhibitor 0.470
Klp10A CG1453 gene product from transcript CG1453-RA 0.468
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.464
CG32479 CG32479 gene product from transcript CG32479-RA 0.462
Ntf-2 Nuclear transport factor-2 0.461
pnt pointed 0.460
msn misshapen 0.460
Dsor1 Downstream of raf1 0.458
Gp150 CG5820 gene product from transcript CG5820-RA 0.458
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Mapk1 mitogen activated protein kinase 1 0.821
Pfn1 profilin 1 0.752
Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.649
Stip1 stress-induced phosphoprotein 1 0.624
Rab6a RAB6A, member RAS oncogene family 0.614
Jak2 Janus kinase 2 0.596
Gria2 glutamate receptor, ionotropic, AMPA 2 0.483
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.482
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.471
Dlgap3 discs, large (Drosophila) homolog-associated protein 3 0.455
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.446
Hsph1 heat shock 105/110 protein 1 0.404
Stxbp1 syntaxin binding protein 1 0.404
Stx12 syntaxin 12 0.390
Myadm myeloid-associated differentiation marker 0.378
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.369
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.365
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.365
Rhoa ras homolog gene family, member A 0.362
Snap25 synaptosomal-associated protein 25 0.361
Tpm3 tropomyosin 3, gamma 0.358
Anxa5 annexin A5 0.355
Syn1 synapsin I 0.354
Arpc1b actin related protein 2/3 complex, subunit 1B 0.339
Rgs19 regulator of G-protein signaling 19 0.336
Canx calnexin 0.334
Pdcl phosducin-like 0.331
Hfe hemochromatosis 0.330
Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.326
Rhob ras homolog gene family, member B 0.326
Rraga Ras-related GTP binding A 0.321
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.320
Accn1 amiloride-sensitive cation channel 1, neuronal 0.319
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform 0.313
Nrxn1 neurexin 1 0.304
Syt4 synaptotagmin IV 0.299
Pde3a phosphodiesterase 3A, cGMP inhibited 0.296
Il1rl1 interleukin 1 receptor-like 1 0.292
Pea15a phosphoprotein enriched in astrocytes 15A 0.291
Cask calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.286
Arf4 ADP-ribosylation factor 4 0.283
Htr4 5-hydroxytryptamine (serotonin) receptor 4 0.281
Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform 0.279
Atxn1 ataxin 1 0.276
Slit3 slit homolog 3 (Drosophila) 0.272
Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.270
Htr2b 5-hydroxytryptamine (serotonin) receptor 2B 0.268
LOC100362824 caveolin 2-like 0.267
Anxa2 annexin A2 0.265
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.265
Adam17 ADAM metallopeptidase domain 17 0.261
Syngr2 synaptogyrin 2 0.256
Arf1 ADP-ribosylation factor 1 0.255
Cast calpastatin 0.254
Grm7 glutamate receptor, metabotropic 7 0.253
Ndfip2 Nedd4 family interacting protein 2 0.252
Actg1 actin, gamma 1 0.250
Syt3 synaptotagmin III 0.247
Ndfip1 Nedd4 family interacting protein 1 0.247
Dynll1 dynein light chain LC8-type 1 0.247
Nlgn3 neuroligin 3 0.245
Myl7 myosin, light chain 7, regulatory 0.243
Taf10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor 0.242
Eif4h eukaryotic translation initiation factor 4H 0.242
Psmc5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.240
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.240
Epn2 epsin 2 0.236
Nlgn1 neuroligin 1 0.234
Dlg4 discs, large homolog 4 (Drosophila) 0.233
Sdcbp syndecan binding protein 0.230
Gfra2 GDNF family receptor alpha 2 0.228
Inppl1 inositol polyphosphate phosphatase-like 1 0.224
Pdc phosducin 0.223
Ctnnd2 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) 0.218
Picalm phosphatidylinositol binding clathrin assembly protein 0.218
Met met proto-oncogene 0.216
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.215
Tcof1 Treacher Collins-Franceschetti syndrome 1 homolog (human) 0.213
Prrx1 paired related homeobox 1 0.212
Dnm1 dynamin 1 0.206
Gria1 glutamate receptor, ionotropic, AMPA 1 0.206
Pggt1b protein geranylgeranyltransferase type I, beta subunit 0.206
LOC100364854 similar to RIKEN cDNA A430107P09 gene-like 0.201
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.201
Eef2 eukaryotic translation elongation factor 2 0.200
Grm5 glutamate receptor, metabotropic 5 0.200
Cttn cortactin 0.198
Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.195
Ppp2r2c protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform 0.195
Serbp1 Serpine1 mRNA binding protein 1 0.194
Gabarapl2 GABA(A) receptor-associated protein like 2 0.194
Ppp2ca protein phosphatase 2, catalytic subunit, alpha isoform 0.193
Dnm1l dynamin 1-like 0.192
Sema6b sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 0.191
Dnajb1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.191
Slc12a4 solute carrier family 12 (potassium/chloride transporters), member 4 0.191
Zranb2 zinc finger, RAN-binding domain containing 2 0.187
Thop1 thimet oligopeptidase 1 0.187
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.187
Pnma1 paraneoplastic antigen MA1 0.187
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism