The network for 'rho protein signal transduction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

rho protein signal transduction

A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.

Caenorhabditis elegans
Name Description Probability Func Analog Organism
sem-5 Protein SEM-5 0.873
mig-2 Protein MIG-2 0.692
unc-73 Protein UNC-73 0.633
egl-8 Protein EGL-8 0.337
lag-1 Protein LAG-1 0.289
let-60 Protein LET-60 0.267
itr-1 Protein ITR-1 0.255
lat-1 Protein LAT-1 0.245
ced-10 Protein CED-10 0.226
pat-3 Protein PAT-3 0.200
sel-12 Protein SEL-12 0.191
abl-1 Protein ABL-1 0.185
C18F10.7 Protein C18F10.7 0.166
bar-1 Protein BAR-1 0.165
egl-18 Protein EGL-18 0.156
C11E4.6 Protein C11E4.6 0.156
plc-3 Protein PLC-3 0.152
afd-1 Protein AFD-1 0.151
sax-3 Protein SAX-3 0.151
ina-1 Protein INA-1 0.148
CELE_F47G4.4 Protein F47G4.4 0.147
T08G11.1 Protein T08G11.1 0.147
flh-2 Protein FLH-2 0.143
smp-1 Protein SMP-1 0.143
T28B11.1 Protein T28B11.1 0.133
madf-5 Protein MADF-5 0.131
ketn-1 Protein KETN-1 0.121
eor-1 Protein EOR-1 0.121
C06G1.5 Protein C06G1.5 0.117
let-756 Protein LET-756 0.115
pig-1 Protein PIG-1 0.113
zfp-3 Protein ZFP-3 0.112
T23F2.2 Protein T23F2.2 0.105
tag-303 Protein TAG-303 0.104
CELE_F14E5.2 Protein F14E5.2 0.104
sop-3 Protein SOP-3 0.103
pry-1 Protein PRY-1 0.103
alx-1 Protein ALX-1 0.102
egrh-1 Protein EGRH-1 0.096
fzr-1 Protein FZR-1 0.092
R08E3.3 Protein R08E3.3 0.087
vhp-1 Protein VHP-1 0.085
par-3 Protein PAR-3 0.084
mpk-1 Protein MPK-1 0.081
sma-6 Protein SMA-6 0.081
T04F8.6 Protein T04F8.6 0.080
rgs-7 Protein RGS-7 0.078
ten-1 Protein TEN-1 0.077
nmy-2 Protein NMY-2 0.069
sax-2 Protein SAX-2 0.068
pup-2 Protein PUP-2 0.068
klp-7 Protein KLP-7 0.067
dpy-21 Protein DPY-21 0.065
hpk-1 Protein HPK-1 0.065
set-19 Protein SET-19 0.064
pqe-1 Protein PQE-1 0.064
lin-12 Protein LIN-12 0.063
rig-6 Protein RIG-6 0.060
vab-8 Protein VAB-8 0.058
ulp-2 Protein ULP-2 0.058
cah-6 Protein CAH-6 0.057
sel-8 Protein SEL-8 0.057
CELE_F52E1.13 Protein F52E1.13 0.056
eor-2 Protein EOR-2 0.056
cnt-2 Protein CNT-2 0.055
CELE_W07A8.2 Protein W07A8.2 0.055
tmc-2 Protein TMC-2 0.055
sto-4 Protein STO-4 0.055
unc-71 Protein UNC-71 0.054
F35G2.1 Protein F35G2.1 0.054
tes-1 Protein TES-1 0.054
sur-2 Protein SUR-2 0.053
cdf-1 Protein CDF-1 0.053
tbb-4 Protein TBB-4 0.053
R148.3 Protein R148.3 0.053
lin-48 Protein LIN-48 0.052
daf-19 Protein DAF-19 0.051
abts-1 Protein ABTS-1 0.051
egl-46 Protein EGL-46 0.050
inx-18 Protein INX-18 0.050
CELE_Y39B6A.42 Protein Y39B6A.42 0.050
pod-1 Protein POD-1 0.047
aip-1 Protein AIP-1 0.046
eat-20 Protein EAT-20 0.046
cdc-42 Protein CDC-42 0.045
hmg-1.2 Protein HMG-1.2 0.045
dpy-22 Protein DPY-22 0.045
rab-39 Protein RAB-39 0.044
trpa-1 Protein TRPA-1 0.044
CELE_T26A8.1 Protein T26A8.1 0.044
CELE_R09F10.3 Protein R09F10.3 0.044
cyk-4 Protein CYK-4 0.043
lin-59 Protein LIN-59 0.043
ncl-1 Protein NCL-1 0.043
cdh-9 Protein CDH-9 0.043
exc-5 Protein EXC-5 0.043
pqn-89 Protein PQN-89 0.043
tag-343 Protein TAG-343 0.042
pld-1 Protein PLD-1 0.042
zip-5 Protein ZIP-5 0.042
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.478
pvrl1b poliovirus receptor-related 1b 0.463
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.264
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.249
gna13a guanine nucleotide binding protein (G protein), alpha 13a 0.247
itgb1b.2 integrin, beta 1b.2 0.236
si:dkeyp-22b2.3 si:dkeyp-22b2.3 0.196
itgb1b integrin, beta 1b 0.146
celsr1a cadherin EGF LAG seven-pass G-type receptor 1a 0.130
gcm2 glial cells missing homolog 2 (Drosophila) 0.127
bactin1 bactin1 0.126
prickle1a prickle-like 1 (Drosophila) a 0.121
pafah1b1a platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a 0.120
gna11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.105
si:dkey-228g21.4 si:dkey-228g21.4 0.100
tpm4 tropomyosin 4 0.100
s100a10b S100 calcium binding protein A10b 0.098
ctnnb1 catenin (cadherin-associated protein), beta 1 0.091
itgb1a integrin, beta 1a 0.089
cnn2 calponin 2 0.081
gnaia guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a 0.077
pycard PYD and CARD domain containing 0.077
prom1a prominin 1a 0.074
gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.072
col11a1a collagen, type XI, alpha 1a 0.069
cdc42 cell division cycle 42 0.065
adrb2a adrenergic receptor, beta 2a 0.065
gnao1a guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a 0.063
icn ictacalcin 0.062
pkd2 polycystic kidney disease 2 0.059
gnat1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.056
arpc5a actin related protein 2/3 complex, subunit 5A 0.056
appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.056
trpv4 transient receptor potential cation channel, subfamily V, member 4 0.056
gna14 guanine nucleotide binding protein (G protein), alpha 14 0.055
arpc5b actin related protein 2/3 complex, subunit 5B 0.053
zbtb4 zinc finger and BTB domain containing 4 0.053
hoxa4a homeo box A4a 0.052
nkd1 naked cuticle homolog 1 (Drosophila) 0.052
otx2 orthodenticle homolog 2 0.051
guk1 guanylate kinase 1 0.050
f2rl1.2 coagulation factor II (thrombin) receptor-like 1.2 0.050
ccdc151 coiled-coil domain containing 151 0.049
gnai2l guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like 0.049
gnav1 guanine nucleotide binding protein (G protein) alpha v1 0.048
egfra epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) 0.047
glcci1 glucocorticoid induced transcript 1 0.046
s100t S100 calcium binding protein T 0.046
cyt1 type I cytokeratin, enveloping layer 0.046
huwe1 HECT, UBA and WWE domain containing 1 0.044
lifrb leukemia inhibitory factor receptor alpha b 0.044
bglap bone gamma-carboxyglutamate (gla) protein 0.044
col1a1a collagen, type I, alpha 1a 0.043
camk2g1 calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1 0.043
kbp kif1-binding protein 0.043
s100z S100 calcium binding protein Z 0.041
myl9l myosin, light polypeptide 9, like 0.041
pde6c phosphodiesterase 6C, cGMP-specific, cone, alpha prime 0.040
grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.040
acvr1b activin A receptor, type IB 0.040
alcamb activated leukocyte cell adhesion molecule b 0.039
krt8 keratin 8 0.039
s100a10a S100 calcium binding protein A10a 0.039
LOC100332929 guanine nucleotide-binding protein subunit alpha-15-like 0.039
capzb capping protein (actin filament) muscle Z-line, beta 0.039
gnas GNAS complex locus 0.039
mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 0.039
LOC100331639 hypothetical protein LOC100331639 0.039
zgc:101761 zgc:101761 0.038
gnat2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.038
nrip1b nuclear receptor interacting protein 1b 0.038
gnaz guanine nucleotide binding protein (G protein), alpha z polypeptide 0.037
zgc:56085 zgc:56085 0.037
satb2 SATB homeobox 2 0.037
nod1 nucleotide-binding oligomerization domain containing 1 0.037
rcv1 recoverin 0.037
ptger2a prostaglandin E receptor 2a (subtype EP2) 0.037
tp63 tumor protein p63 0.036
lama1 laminin, alpha 1 0.036
rnd3a Rho family GTPase 3a 0.036
plod1a procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a 0.036
col5a2l collagen, type V, alpha 2-like 0.036
crx cone-rod homeobox 0.036
ppp3cb protein phosphatase 3, catalytic subunit, beta isozyme 0.035
sb:cb730 sb:cb730 0.035
msna moesin a 0.035
ptges prostaglandin E synthase 0.034
fgfrl1b fibroblast growth factor receptor-like 1b 0.034
zgc:92392 zgc:92392 0.034
mc3r melanocortin 3 receptor 0.034
anxa1a annexin A1a 0.034
col14a1 collagen, type XIV, alpha 1 0.034
pknox1.2 pbx/knotted 1 homeobox 1.2 0.033
cacnb2a calcium channel, voltage-dependent, beta 2a 0.033
epb4.1l4 erythrocyte protein band 4.1-like 4 0.033
klf2b Kruppel-like factor 2b 0.033
anxa2a annexin A2a 0.032
dclk2 doublecortin-like kinase 2 0.032
itgb1b.1 integrin, beta 1b.1 0.032
igfbp6a insulin-like growth factor binding protein 6a 0.032
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
mbc myoblast city 0.921
plexB plexin B 0.861
trio CG18214 gene product from transcript CG18214-RA 0.860
Pkn Protein kinase related to protein kinase N 0.821
msn misshapen 0.776
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.754
flw flapwing 0.684
RhoGAP93B CG3421 gene product from transcript CG3421-RA 0.519
rok Rho-kinase 0.476
pod1 CG4532 gene product from transcript CG4532-RF 0.442
Rho1 CG8416 gene product from transcript CG8416-RB 0.419
Pten CG5671 gene product from transcript CG5671-RB 0.394
S6k RPS6-p70-protein kinase 0.385
Abi Abelson interacting protein 0.361
LIMK1 LIM-kinase1 0.347
dos daughter of sevenless 0.344
Mkp3 Mitogen-activated protein kinase phosphatase 3 0.324
vav CG7893 gene product from transcript CG7893-RB 0.322
p120ctn Adherens junction protein p120 0.311
Akt1 CG4006 gene product from transcript CG4006-RA 0.310
Mer Merlin 0.296
drk downstream of receptor kinase 0.291
Arf79F ADP ribosylation factor 79F 0.280
Rala Ras-related protein 0.272
Wnk CG7177 gene product from transcript CG7177-RA 0.242
ttk tramtrack 0.231
crb crumbs 0.231
Rac2 CG8556 gene product from transcript CG8556-RA 0.221
CG32772 CG32772 gene product from transcript CG32772-RC 0.221
neuroligin CG13772 gene product from transcript CG13772-RA 0.220
Pk61C Protein kinase 61C 0.215
chic chickadee 0.206
UBL3 CG9038 gene product from transcript CG9038-RC 0.206
CG3573 CG3573 gene product from transcript CG3573-RA 0.198
nwk nervous wreck 0.198
l(2)k16918 lethal (2) k16918 0.194
puc puckered 0.191
Fak56D Focal Adhesion Kinase 0.185
Mtl Mig-2-like 0.182
Ephrin CG1862 gene product from transcript CG1862-RA 0.175
cta concertina 0.175
Hem HEM-protein 0.168
Ced-12 CG5336 gene product from transcript CG5336-RA 0.162
CG4853 CG4853 gene product from transcript CG4853-RA 0.160
Rheb CG1081 gene product from transcript CG1081-RA 0.141
Pak PAK-kinase 0.139
Pak3 CG14895 gene product from transcript CG14895-RA 0.126
Shc SHC-adaptor protein 0.125
gig gigas 0.120
WASp CG1520 gene product from transcript CG1520-RA 0.118
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.117
dia diaphanous 0.117
da daughterless 0.113
Apc APC-like 0.112
RanBPM Ran-binding protein M 0.110
hep hemipterous 0.105
RhoGAPp190 CG32555 gene product from transcript CG32555-RB 0.101
phl pole hole 0.101
synj synaptojanin 0.099
Gug Grunge 0.098
ttv tout-velu 0.097
alpha-Man-IIb CG4606 gene product from transcript CG4606-RA 0.092
unc-104 CG8566 gene product from transcript CG8566-RB 0.090
stnB stoned B 0.089
dock dreadlocks 0.089
mys myospheroid 0.088
stg string 0.085
kst karst 0.084
htl heartless 0.083
bif bifocal 0.082
Vps16A Vacuolar protein sorting 16A 0.081
tkv thickveins 0.081
MTF-1 Metal response element-binding Transcription Factor-1 0.077
oys oysgedart 0.076
jeb jelly belly 0.075
kay kayak 0.075
NetB Netrin-B 0.073
Arf51F ADP ribosylation factor 51F 0.073
shot short stop 0.071
Trim9 CG31721 gene product from transcript CG31721-RB 0.070
hipk homeodomain interacting protein kinase 0.070
mbt mushroom bodies tiny 0.070
CG17233 CG17233 gene product from transcript CG17233-RA 0.070
RhoGEF2 CG9635 gene product from transcript CG9635-RF 0.069
CG11376 CG11376 gene product from transcript CG11376-RA 0.069
csw corkscrew 0.069
Fas3 Fasciclin 3 0.068
Hip1 Huntingtin interacting protein 1 0.068
CG2991 CG2991 gene product from transcript CG2991-RA 0.067
R Roughened 0.067
disco disconnected 0.067
CG3764 CG3764 gene product from transcript CG3764-RA 0.066
kuz kuzbanian 0.065
CG17082 CG17082 gene product from transcript CG17082-RD 0.064
CG17159 CG17159 gene product from transcript CG17159-RF 0.063
l(3)04053 lethal (3) 04053 0.063
Cad87A CG6977 gene product from transcript CG6977-RA 0.063
nerfin-1 nervous fingers 1 0.063
Drl-2 Derailed 2 0.062
RhoL rho-like 0.062
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
EGFR epidermal growth factor receptor 1.000
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.000
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 1.000
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.000
SFN stratifin 1.000
RHOA ras homolog gene family, member A 0.999
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.999
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.998
PTK2 PTK2 protein tyrosine kinase 2 0.998
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.998
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.997
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.997
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.996
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.996
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.996
S100A6 S100 calcium binding protein A6 0.995
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.994
S100A11 S100 calcium binding protein A11 0.993
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.992
SH3KBP1 SH3-domain kinase binding protein 1 0.990
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.986
ABI1 abl-interactor 1 0.986
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.984
SOS1 son of sevenless homolog 1 (Drosophila) 0.980
S100A8 S100 calcium binding protein A8 0.979
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.979
S100B S100 calcium binding protein B 0.977
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.975
GRB7 growth factor receptor-bound protein 7 0.972
PLCG1 phospholipase C, gamma 1 0.970
DSP desmoplakin 0.970
IGF1R insulin-like growth factor 1 receptor 0.968
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.967
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.965
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.963
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.962
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.951
ARRB2 arrestin, beta 2 0.951
FOS FBJ murine osteosarcoma viral oncogene homolog 0.945
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 0.943
GRB2 growth factor receptor-bound protein 2 0.940
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.940
DOCK1 dedicator of cytokinesis 1 0.937
COL1A1 collagen, type I, alpha 1 0.937
TRIP6 thyroid hormone receptor interactor 6 0.932
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.927
COL3A1 collagen, type III, alpha 1 0.925
COL1A2 collagen, type I, alpha 2 0.924
FLOT2 flotillin 2 0.921
BAIAP2 BAI1-associated protein 2 0.920
RICTOR RPTOR independent companion of MTOR, complex 2 0.917
TRAF5 TNF receptor-associated factor 5 0.913
EPHA2 EPH receptor A2 0.912
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.911
ARHGAP1 Rho GTPase activating protein 1 0.903
CCR5 chemokine (C-C motif) receptor 5 0.901
S100A9 S100 calcium binding protein A9 0.895
CAV1 caveolin 1, caveolae protein, 22kDa 0.893
PXN paxillin 0.885
MET met proto-oncogene (hepatocyte growth factor receptor) 0.882
RIN1 Ras and Rab interactor 1 0.880
PKN3 protein kinase N3 0.874
APC adenomatous polyposis coli 0.873
JUP junction plakoglobin 0.868
RND1 Rho family GTPase 1 0.866
SH3BP2 SH3-domain binding protein 2 0.864
BCAR1 breast cancer anti-estrogen resistance 1 0.863
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.860
PKP3 plakophilin 3 0.860
RHOC ras homolog gene family, member C 0.853
ATP7A ATPase, Cu++ transporting, alpha polypeptide 0.845
ITGB4 integrin, beta 4 0.843
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog 0.840
TRADD TNFRSF1A-associated via death domain 0.831
S100A1 S100 calcium binding protein A1 0.830
TSC2 tuberous sclerosis 2 0.828
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.827
SH3RF1 SH3 domain containing ring finger 1 0.824
LIMS1 LIM and senescent cell antigen-like domains 1 0.817
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.813
RPTOR regulatory associated protein of MTOR, complex 1 0.808
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.796
SH3RF3 SH3 domain containing ring finger 3 0.793
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.791
S100A4 S100 calcium binding protein A4 0.790
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.790
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.787
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.780
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.777
BBS10 Bardet-Biedl syndrome 10 0.776
MARK3 MAP/microtubule affinity-regulating kinase 3 0.775
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.765
ERBB2IP erbb2 interacting protein 0.760
SMAD2 SMAD family member 2 0.752
DSG2 desmoglein 2 0.749
PSEN1 presenilin 1 0.715
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.706
RAB5A RAB5A, member RAS oncogene family 0.703
NCKAP1 NCK-associated protein 1 0.702
KCTD10 potassium channel tetramerisation domain containing 10 0.702
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Epha4 Eph receptor A4 0.999
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.996
Efnb2 ephrin B2 0.980
Ret ret proto-oncogene 0.972
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.966
Ntf3 neurotrophin 3 0.960
Plxnb1 plexin B1 0.947
Ephb2 Eph receptor B2 0.946
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.945
Lrp1 low density lipoprotein receptor-related protein 1 0.917
Nf1 neurofibromatosis 1 0.912
Ptk2 PTK2 protein tyrosine kinase 2 0.912
Rac1 RAS-related C3 botulinum substrate 1 0.907
Nos3 nitric oxide synthase 3, endothelial cell 0.901
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.890
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.885
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.884
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.867
Wnt5a wingless-related MMTV integration site 5A 0.860
Lama5 laminin, alpha 5 0.837
Shc1 src homology 2 domain-containing transforming protein C1 0.832
Ctnnb1 catenin (cadherin associated protein), beta 1 0.815
Arrb2 arrestin, beta 2 0.812
Apc adenomatosis polyposis coli 0.806
Dock1 dedicator of cytokinesis 1 0.796
Dlg4 discs, large homolog 4 (Drosophila) 0.793
Myo1f myosin IF 0.792
Lepr leptin receptor 0.770
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.762
Ncf1 neutrophil cytosolic factor 1 0.757
Fzd1 frizzled homolog 1 (Drosophila) 0.744
Rtkn rhotekin 0.741
Ccr2 chemokine (C-C motif) receptor 2 0.726
Nckap1l NCK associated protein 1 like 0.719
Ldb2 LIM domain binding 2 0.717
Vcl vinculin 0.710
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.708
Braf Braf transforming gene 0.700
Sox10 SRY-box containing gene 10 0.686
Ccr1 chemokine (C-C motif) receptor 1 0.685
Grb2 growth factor receptor bound protein 2 0.681
Vav1 vav 1 oncogene 0.673
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.673
Cbl Casitas B-lineage lymphoma 0.668
Gli3 GLI-Kruppel family member GLI3 0.664
Col3a1 collagen, type III, alpha 1 0.654
Plcg1 phospholipase C, gamma 1 0.652
Ephb3 Eph receptor B3 0.648
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.645
Vdr vitamin D receptor 0.635
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.630
Pax8 paired box gene 8 0.629
Pik3cb phosphatidylinositol 3-kinase, catalytic, beta polypeptide 0.628
Selplg selectin, platelet (p-selectin) ligand 0.628
Flii flightless I homolog (Drosophila) 0.623
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.621
Pax1 paired box gene 1 0.616
Mmp15 matrix metallopeptidase 15 0.605
Tgfb1 transforming growth factor, beta 1 0.602
Bcl6b B-cell CLL/lymphoma 6, member B 0.600
Sh3pxd2a SH3 and PX domains 2A 0.599
Ptk7 PTK7 protein tyrosine kinase 7 0.598
Itgal integrin alpha L 0.595
Git1 G protein-coupled receptor kinase-interactor 1 0.592
Mapk3 mitogen-activated protein kinase 3 0.589
Sell selectin, lymphocyte 0.588
Nrg1 neuregulin 1 0.579
Celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) 0.574
Mmp9 matrix metallopeptidase 9 0.573
Dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.569
Ccl5 chemokine (C-C motif) ligand 5 0.568
Cd44 CD44 antigen 0.568
Snai1 snail homolog 1 (Drosophila) 0.567
Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.564
Plxna3 plexin A3 0.563
Eln elastin 0.559
Emp2 epithelial membrane protein 2 0.558
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.558
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.556
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.552
Slfn1 schlafen 1 0.550
Mapkap1 mitogen-activated protein kinase associated protein 1 0.548
Ccl2 chemokine (C-C motif) ligand 2 0.543
Ednrb endothelin receptor type B 0.537
Pcdh12 protocadherin 12 0.535
Abcg1 ATP-binding cassette, sub-family G (WHITE), member 1 0.535
Mrc2 mannose receptor, C type 2 0.530
Fgf8 fibroblast growth factor 8 0.526
Cx3cr1 chemokine (C-X3-C) receptor 1 0.516
S1pr1 sphingosine-1-phosphate receptor 1 0.516
Cd37 CD37 antigen 0.516
Ncor2 nuclear receptor co-repressor 2 0.515
Apbb1ip amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.515
Cttn cortactin 0.510
Sash3 SAM and SH3 domain containing 3 0.509
Ptprc protein tyrosine phosphatase, receptor type, C 0.509
Tnks1bp1 tankyrase 1 binding protein 1 0.504
Aplnr apelin receptor 0.503
Plxna1 plexin A1 0.500
Pdgfb platelet derived growth factor, B polypeptide 0.499
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Col5a2 collagen, type V, alpha 2 0.049
Ncan neurocan 0.040
Klf6 Kruppel-like factor 6 0.039
Syt11 synaptotagmin XI 0.039
Synpo synaptopodin 0.038
Lum lumican 0.037
Vim vimentin 0.034
Ptafr platelet-activating factor receptor 0.033
LOC100360986 mCG1035404-like 0.033
Kcnab1 potassium voltage-gated channel, shaker-related subfamily, beta member 1 0.032
Rap1b RAP1B, member of RAS oncogene family 0.032
Taok1 TAO kinase 1 0.031
Atf3 activating transcription factor 3 0.030
Arpc3 actin related protein 2/3 complex, subunit 3 0.029
Gja4 gap junction protein, alpha 4 0.029
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.029
Shank2 SH3 and multiple ankyrin repeat domains 2 0.028
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.027
Sh2b3 SH2B adaptor protein 3 0.027
Rfx2 regulatory factor X, 2 (influences HLA class II expression) 0.026
Ncf4 neutrophil cytosolic factor 4 0.026
S1pr2 sphingosine-1-phosphate receptor 2 0.026
RGD1309102 similar to TRS85 homolog 0.026
Olr416 olfactory receptor 416 0.025
Ptgfrn prostaglandin F2 receptor negative regulator 0.025
Rph3a rabphilin 3A 0.025
Col12a1 collagen, type XII, alpha 1 0.024
Dgkg diacylglycerol kinase, gamma 0.024
Sept10 septin 10 0.024
Dock9 dedicator of cytokinesis 9 0.024
Postn periostin, osteoblast specific factor 0.024
Fgfr2 fibroblast growth factor receptor 2 0.024
Rims1 regulating synaptic membrane exocytosis 1 0.024
Loxl1 lysyl oxidase-like 1 0.024
Vcam1 vascular cell adhesion molecule 1 0.023
Atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.023
P2ry14 purinergic receptor P2Y, G-protein coupled, 14 0.023
Epn3 epsin 3 0.023
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.023
Gabra5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 0.023
Calu calumenin 0.023
Plat plasminogen activator, tissue 0.023
Slc24a2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 0.023
Ppp4r2 protein phosphatase 4, regulatory subunit 2 0.023
Prkcd protein kinase C, delta 0.023
Lcp2 lymphocyte cytosolic protein 2 0.023
Mfrp membrane frizzled-related protein 0.023
Accn1 amiloride-sensitive cation channel 1, neuronal 0.022
Gad2 glutamate decarboxylase 2 0.022
Capn2 calpain 2 0.022
Jak2 Janus kinase 2 0.022
Fstl1 follistatin-like 1 0.022
Acvrl1 activin A receptor type II-like 1 0.022
Gltp glycolipid transfer protein 0.022
Rhoa ras homolog gene family, member A 0.022
Fkbp1a FK506 binding protein 1a 0.022
Plxnd1 plexin D1 0.022
Dlg3 discs, large homolog 3 (Drosophila) 0.022
Anxa4 annexin A4 0.022
N5 DNA binding protein N5 0.022
Agrn agrin 0.022
Myl9 myosin, light chain 9, regulatory 0.022
Adarb2 adenosine deaminase, RNA-specific, B2 0.022
Vsnl1 visinin-like 1 0.022
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.022
Bcat1 branched chain aminotransferase 1, cytosolic 0.021
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.021
Ylpm1 YLP motif containing 1 0.021
Cnih4 cornichon homolog 4 (Drosophila) 0.021
Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.021
Asam adipocyte-specific adhesion molecule 0.021
Arf6 ADP-ribosylation factor 6 0.021
Sirpa signal-regulatory protein alpha 0.021
Ier5 immediate early response 5 0.021
Cstb cystatin B (stefin B) 0.021
Stxbp5 syntaxin binding protein 5 (tomosyn) 0.021
Gata2 GATA binding protein 2 0.021
Mmp9 matrix metallopeptidase 9 0.021
Bgn biglycan 0.021
Fgf7 fibroblast growth factor 7 0.021
Sv2b synaptic vesicle glycoprotein 2b 0.021
Olr1500 olfactory receptor 1500 0.021
Pmp22 peripheral myelin protein 22 0.020
Gfra2 GDNF family receptor alpha 2 0.020
Dlgap3 discs, large (Drosophila) homolog-associated protein 3 0.020
Spata2 spermatogenesis associated 2 0.020
Plekhg2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 0.020
Rup2 urinary protein 2 0.020
Atf2 activating transcription factor 2 0.020
Sptbn1 spectrin, beta, non-erythrocytic 1 0.020
Edn1 endothelin 1 0.020
Aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.020
Col1a2 collagen, type I, alpha 2 0.020
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.020
Uhmk1 U2AF homology motif (UHM) kinase 1 0.020
Pcolce procollagen C-endopeptidase enhancer 0.020
Rasa1 RAS p21 protein activator (GTPase activating protein) 1 0.020
Ar androgen receptor 0.020
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.020
Crispld2 cysteine-rich secretory protein LCCL domain containing 2 0.020
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
RHO1 Rho1p 0.495
CDC24 Cdc24p 0.390
PKC1 Pkc1p 0.241
ROM2 Rom2p 0.163
BEM3 Bem3p 0.121
MKK1 Mkk1p 0.075
TOR1 Tor1p 0.073
WSC3 Wsc3p 0.072
ACK1 Ack1p 0.065
KOG1 Kog1p 0.065
GIC2 Gic2p 0.060
SEC3 Sec3p 0.056
MDS3 Mds3p 0.054
SLG1 Slg1p 0.051
IRA1 Ira1p 0.049
MID2 Mid2p 0.048
TCO89 Tco89p 0.037
AVO1 Avo1p 0.037
KAP120 Kap120p 0.034
EXO84 Exo84p 0.033
OSH7 Osh7p 0.032
TSC11 Tsc11p 0.026
PEP5 Pep5p 0.026
FYV8 Fyv8p 0.025
BEM2 Bem2p 0.024
YPK1 Ypk1p 0.024
SLM1 Slm1p 0.022
CHS1 Chs1p 0.022
RSN1 Rsn1p 0.021
BIT61 Bit61p 0.021
YLR264C-A hypothetical protein 0.020
SRD1 Srd1p 0.020
RHO4 Rho4p 0.020
BOI1 Boi1p 0.020
SIA1 Sia1p 0.020
WSC2 Wsc2p 0.020
FAR1 Far1p 0.020
YLR162W hypothetical protein 0.020
KEL1 Kel1p 0.020
URA3 Ura3p 0.020
PRS2 Prs2p 0.019
BEM1 Bem1p 0.019
YOL038C-A hypothetical protein 0.019
TAO3 Tao3p 0.019
SUR7 Sur7p 0.019
VAC7 Vac7p 0.018
LEU2 Leu2p 0.018
YLR108C hypothetical protein 0.018
SAC7 Sac7p 0.018
MER1 Mer1p 0.018
GDS1 Gds1p 0.018
YLR049C hypothetical protein 0.017
ARG8 Arg8p 0.017
YDR186C hypothetical protein 0.017
BEM4 Bem4p 0.017
FIR1 Fir1p 0.017
YDR034W-B hypothetical protein 0.017
CUP1-1 Cup1-1p 0.016
GIP2 Gip2p 0.016
MBF1 Mbf1p 0.016
LRE1 Lre1p 0.016
ZPS1 Zps1p 0.016
CUR1 Cur1p 0.016
SPL2 Spl2p 0.016
FAA2 Faa2p 0.016
TRL1 Trl1p 0.016
SEC15 Sec15p 0.015
YAR068W hypothetical protein 0.015
ELP6 Elp6p 0.015
YBR013C hypothetical protein 0.015
YJL181W hypothetical protein 0.015
PRM4 Prm4p 0.015
ARP10 Arp10p 0.015
ATP6 Atp6p 0.015
CPD1 Cpd1p 0.015
VPS15 Vps15p 0.015
DAS2 Das2p 0.015
UPS3 Ups3p 0.014
OPT2 Opt2p 0.014
ICS2 Ics2p 0.014
ENA2 Ena2p 0.014
ATG13 Atg13p 0.014
YEL073C hypothetical protein 0.014
SEN54 Sen54p 0.014
TFA1 Tfa1p 0.014
HKR1 Hkr1p 0.014
MRS3 Mrs3p 0.014
PHM6 Phm6p 0.014
SUT1 Sut1p 0.014
HLJ1 Hlj1p 0.014
SSP1 Ssp1p 0.014
YLR042C hypothetical protein 0.014
AUA1 Aua1p 0.014
APT2 Apt2p 0.013
CDC55 Cdc55p 0.013
SGE1 Sge1p 0.013
YPL066W hypothetical protein 0.013
MF(ALPHA)2 Mf(alpha)2p 0.013
CDC1 Cdc1p 0.013
PTR2 Ptr2p 0.013