The network for 'keratinocyte migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

keratinocyte migration

The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another.

Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
FGFR2 fibroblast growth factor receptor 2 1.000
FGF1 fibroblast growth factor 1 (acidic) 0.987
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.925
TP63 tumor protein p63 0.922
KRT17 keratin 17 0.855
ABI2 abl-interactor 2 0.843
KRT15 keratin 15 0.813
THBS1 thrombospondin 1 0.607
PLAU plasminogen activator, urokinase 0.430
FGF10 fibroblast growth factor 10 0.400
KRT14 keratin 14 0.398
FGFR1 fibroblast growth factor receptor 1 0.354
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.306
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.283
PKP1 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) 0.245
DLG1 discs, large homolog 1 (Drosophila) 0.213
KRT19 keratin 19 0.212
ITGAV integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) 0.205
KRT6C keratin 6C 0.192
KRT5 keratin 5 0.165
PLAT plasminogen activator, tissue 0.164
KRT6A keratin 6A 0.150
TCF4 transcription factor 4 0.116
TGFB1 transforming growth factor, beta 1 0.106
PLAUR plasminogen activator, urokinase receptor 0.100
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.094
SH3D19 SH3 domain containing 19 0.090
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.083
KRT34 keratin 34 0.077
MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase) 0.071
KRT18 keratin 18 0.068
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.059
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.058
FGF7 fibroblast growth factor 7 0.056
FN1 fibronectin 1 0.054
GJB3 gap junction protein, beta 3, 31kDa 0.051
C19orf50 chromosome 19 open reading frame 50 0.046
KRT2 keratin 2 0.046
PTHLH parathyroid hormone-like hormone 0.043
FGFBP1 fibroblast growth factor binding protein 1 0.043
INHBA inhibin, beta A 0.041
ALOX12 arachidonate 12-lipoxygenase 0.038
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.037
SPRR1B small proline-rich protein 1B 0.037
SPRR1A small proline-rich protein 1A 0.036
PPL periplakin 0.035
TIMP2 TIMP metallopeptidase inhibitor 2 0.033
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.031
KRT4 keratin 4 0.030
KRT1 keratin 1 0.030
KRT75 keratin 75 0.028
TRIM29 tripartite motif containing 29 0.027
ENG endoglin 0.026
S100A2 S100 calcium binding protein A2 0.026
KRT16 keratin 16 0.024
IGFBP3 insulin-like growth factor binding protein 3 0.024
FGFR3 fibroblast growth factor receptor 3 0.024
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.023
THBS2 thrombospondin 2 0.020
PDIA3 protein disulfide isomerase family A, member 3 0.020
FGF2 fibroblast growth factor 2 (basic) 0.018
IVL involucrin 0.016
VCL vinculin 0.014
PDPN podoplanin 0.014
COL10A1 collagen, type X, alpha 1 0.013
KRT85 keratin 85 0.013
LY6D lymphocyte antigen 6 complex, locus D 0.013
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.013
KRT9 keratin 9 0.012
NRP2 neuropilin 2 0.012
DSG3 desmoglein 3 0.012
SPRR3 small proline-rich protein 3 0.012
BMP1 bone morphogenetic protein 1 0.011
FRS2 fibroblast growth factor receptor substrate 2 0.011
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.011
CCL7 chemokine (C-C motif) ligand 7 0.011
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.010
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.010
CYR61 cysteine-rich, angiogenic inducer, 61 0.010
MMP13 matrix metallopeptidase 13 (collagenase 3) 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Nos2 nitric oxide synthase 2, inducible 0.957
Il10 interleukin 10 0.882
Msr1 macrophage scavenger receptor 1 0.871
Ptgs2 prostaglandin-endoperoxide synthase 2 0.870
Lep leptin 0.816
Lepr leptin receptor 0.813
Mmp8 matrix metallopeptidase 8 0.812
Plau plasminogen activator, urokinase 0.808
Cd44 CD44 antigen 0.793
Csf1 colony stimulating factor 1 (macrophage) 0.761
Fpr1 formyl peptide receptor 1 0.731
C5ar1 complement component 5a receptor 1 0.720
Clec4e C-type lectin domain family 4, member e 0.691
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.676
Clec4d C-type lectin domain family 4, member d 0.672
Insr insulin receptor 0.669
Cav1 caveolin 1, caveolae protein 0.667
Tlr4 toll-like receptor 4 0.632
Klra2 killer cell lectin-like receptor, subfamily A, member 2 0.624
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.581
Slfn4 schlafen 4 0.551
Fpr2 formyl peptide receptor 2 0.548
Tgfb1 transforming growth factor, beta 1 0.472
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.471
Nos3 nitric oxide synthase 3, endothelial cell 0.467
Selp selectin, platelet 0.457
Ccr2 chemokine (C-C motif) receptor 2 0.433
Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) 0.390
Smad3 MAD homolog 3 (Drosophila) 0.387
Cxcl2 chemokine (C-X-C motif) ligand 2 0.379
Hr hairless 0.378
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.372
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.359
Ccr1 chemokine (C-C motif) receptor 1 0.330
Il1a interleukin 1 alpha 0.326
Il1b interleukin 1 beta 0.314
Plaur plasminogen activator, urokinase receptor 0.287
Rxra retinoid X receptor alpha 0.278
Egfr epidermal growth factor receptor 0.252
C78513 EST C78513 0.251
Adam17 a disintegrin and metallopeptidase domain 17 0.242
Cxcr2 chemokine (C-X-C motif) receptor 2 0.226
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.221
Il6st interleukin 6 signal transducer 0.215
Hif1a hypoxia inducible factor 1, alpha subunit 0.212
Has1 hyaluronan synthase1 0.210
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.209
Aoah acyloxyacyl hydrolase 0.206
Plin1 perilipin 1 0.205
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.202
Nos1 nitric oxide synthase 1, neuronal 0.187
Itga5 integrin alpha 5 (fibronectin receptor alpha) 0.185
Il1rn interleukin 1 receptor antagonist 0.184
Apoe apolipoprotein E 0.183
Chi3l3 chitinase 3-like 3 0.183
Spry4 sprouty homolog 4 (Drosophila) 0.173
Il6 interleukin 6 0.163
Pnpla2 patatin-like phospholipase domain containing 2 0.163
Itgb2l integrin beta 2-like 0.152
Fpr3 formyl peptide receptor 3 0.149
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.148
Fcgr1 Fc receptor, IgG, high affinity I 0.146
Dmbt1 deleted in malignant brain tumors 1 0.145
Pvr poliovirus receptor 0.142
Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.141
Irg1 immunoresponsive gene 1 0.139
F10 coagulation factor X 0.133
Fpr-rs4 formyl peptide receptor, related sequence 4 0.119
Slfn1 schlafen 1 0.118
Ccl2 chemokine (C-C motif) ligand 2 0.117
Slc10a6 solute carrier family 10 (sodium/bile acid cotransporter family), member 6 0.112
Phex phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) 0.111
Siglece sialic acid binding Ig-like lectin E 0.110
Saa4 serum amyloid A 4 0.107
Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 0.106
Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 0.104
Gata4 GATA binding protein 4 0.102
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.101
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.101
Fosl1 fos-like antigen 1 0.101
Nr1i3 nuclear receptor subfamily 1, group I, member 3 0.099
Trp53 transformation related protein 53 0.099
Clock circadian locomotor output cycles kaput 0.097
Mc3r melanocortin 3 receptor 0.096
Ier3 immediate early response 3 0.095
Tlr8 toll-like receptor 8 0.095
Saa3 serum amyloid A 3 0.094
Cidec cell death-inducing DFFA-like effector c 0.089
Ccl4 chemokine (C-C motif) ligand 4 0.089
Slc34a2 solute carrier family 34 (sodium phosphate), member 2 0.087
Itgam integrin alpha M 0.085
Il1r2 interleukin 1 receptor, type II 0.085
F7 coagulation factor VII 0.084
Nr1i2 nuclear receptor subfamily 1, group I, member 2 0.082
1100001G20Rik RIKEN cDNA 1100001G20 gene 0.079
Mmp13 matrix metallopeptidase 13 0.077
Rag1 recombination activating gene 1 0.076
Col1a1 collagen, type I, alpha 1 0.076
Thbs1 thrombospondin 1 0.075
Bst1 bone marrow stromal cell antigen 1 0.074
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Rattus norvegicus
Name Description Probability Func Analog Organism
Cxcl2 chemokine (C-X-C motif) ligand 2 0.053
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.052
Plaur plasminogen activator, urokinase receptor 0.044
Il6 interleukin 6 0.029
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.026
Tnfaip6 tumor necrosis factor alpha induced protein 6 0.023
Fosl1 fos-like antigen 1 0.022
PVR poliovirus receptor 0.022
A3galt2 alpha 1,3-galactosyltransferase 2 0.021
Ankrd1 ankyrin repeat domain 1 (cardiac muscle) 0.020
Gja1 gap junction protein, alpha 1 0.018
Ccl2 chemokine (C-C motif) ligand 2 0.018
Plau plasminogen activator, urokinase 0.017
Ccl4 chemokine (C-C motif) ligand 4 0.016
Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a 0.016
Trib1 tribbles homolog 1 (Drosophila) 0.015
Marcksl1 MARCKS-like 1 0.014
Mmp9 matrix metallopeptidase 9 0.014
Ier5 immediate early response 5 0.014
Ccl11 chemokine (C-C motif) ligand 11 0.013
Pgf placental growth factor 0.012
Csrp3 cysteine and glycine-rich protein 3 0.012
Foxo3 forkhead box O3 0.011
Otp orthopedia homeobox 0.011
F2rl1 coagulation factor II (thrombin) receptor-like 1 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism