The network for 'regulation of vitamin metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of vitamin metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.

Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
lef1 lymphocyte enhancer binding factor 1 0.589
six1b sine oculis homeobox homolog 1b 0.399
gro1 groucho 1 0.273
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.183
axin1 axin 1 0.178
gro2 groucho 2 0.144
wnt3 wingless-type MMTV integration site family, member 3 0.132
smad5 MAD homolog 5 (Drosophila) 0.078
tcf7l1a transcription factor 7-like 1a (T-cell specific, HMG-box) 0.077
pcsk5a proprotein convertase subtilisin/kexin type 5a 0.075
hmx2 H6 family homeobox 2 0.072
ush1c Usher syndrome 1C (autosomal recessive, severe) 0.068
tbx1 T-box 1 0.064
lmo4a LIM domain only 4a 0.059
kitb kit receptor b 0.057
fzd7b frizzled homolog 7b 0.057
acvr1b activin A receptor, type IB 0.050
LOC566708 FL cytokine receptor-like 0.045
gdf6a growth differentiation factor 6a 0.043
med25 mediator of RNA polymerase II transcription, subunit 25 homolog (yeast) 0.042
ephb4b eph receptor B4b 0.039
eya1 eyes absent homolog 1 0.037
klf4 Kruppel-like factor 4 0.032
smad2 MAD homolog 2 (Drosophila) 0.029
rorb RAR-related orphan receptor B 0.029
smo smoothened homolog (Drosophila) 0.028
hoxb6a homeo box B6a 0.026
sox11b SRY-box containing gene 11b 0.025
irx2a iroquois homeobox protein 2, a 0.025
sec31a sec31 homolog A (S. cerevisiae) 0.024
supt6h suppressor of Ty 6 homolog 0.024
lmna lamin A 0.024
si:dkeyp-7c9.1 si:dkeyp-7c9.1 0.023
ahctf1 AT hook containing transcription factor 1 0.023
il17rd interleukin 17 receptor D 0.023
wu:fv91b12 wu:fv91b12 0.022
myh11a myosin, heavy polypeptide 11, smooth muscle a 0.022
cdh23 cadherin-like 23 0.022
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.021
celf1 cugbp, Elav-like family member 1 0.021
frem1a Fras1 related extracellular matrix 1a 0.021
rac1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.020
bcl2 B-cell leukemia/lymphoma 2 0.019
bmpr1aa bone morphogenetic protein receptor, type 1aa 0.019
LOC100151531 zinc finger protein Gfi-1b-like 0.019
notch3 notch homolog 3 0.018
wnt5b wingless-type MMTV integration site family, member 5b 0.018
axin2 axin 2 (conductin, axil) 0.018
spsb4a splA/ryanodine receptor domain and SOCS box containing 4a 0.017
ptprk protein tyrosine phosphatase, receptor type, K 0.017
cldn7b claudin 7b 0.016
ddx46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.016
msxc muscle segment homeobox C 0.016
tfr1a transferrin receptor 1a 0.015
ryk receptor-like tyrosine kinase 0.015
si:ch211-198a12.6 si:ch211-198a12.6 0.015
dacha dachshund a 0.015
sufu suppressor of fused homolog (Drosophila) 0.015
zgc:65979 zgc:65979 0.015
si:ch1073-351m12.1 si:ch1073-351m12.1 0.015
kdrl kinase insert domain receptor like 0.014
hsp47 heat shock protein 47 0.014
hmx3 homeo box (H6 family) 3 0.014
acvr1l activin A receptor, type I like 0.013
slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 0.013
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.013
zgc:66479 zgc:66479 0.013
brd8 bromodomain containing 8 0.013
fbn2b fibrillin 2b 0.013
flr fleer 0.012
nrg1 neuregulin 1 0.012
zgc:171553 zgc:171553 0.011
jub jub, ajuba homolog (Xenopus laevis) 0.011
bmp2b bone morphogenetic protein 2b 0.011
hmcn1 hemicentin 1 0.011
fgfr1a fibroblast growth factor receptor 1a 0.011
fgf3 fibroblast growth factor 3 0.011
fras1 Fraser syndrome 1 0.011
prrx1a paired related homeobox 1a 0.011
wu:fa07b03 wu:fa07b03 0.010
pbx4 pre-B-cell leukemia transcription factor 4 0.010
frem2a Fras1 related extracellular matrix protein 2a 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.000
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.000
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 1.000
RELB v-rel reticuloendotheliosis viral oncogene homolog B 1.000
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.990
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.963
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.929
BCL3 B-cell CLL/lymphoma 3 0.924
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.744
IL1R1 interleukin 1 receptor, type I 0.693
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.637
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) 0.419
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.249
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.154
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.135
TNIP1 TNFAIP3 interacting protein 1 0.080
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.049
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.046
TNIP2 TNFAIP3 interacting protein 2 0.044
IL1RN interleukin 1 receptor antagonist 0.038
JUB jub, ajuba homolog (Xenopus laevis) 0.035
IL1RAP interleukin 1 receptor accessory protein 0.035
ZC3H12A zinc finger CCCH-type containing 12A 0.033
IL1R2 interleukin 1 receptor, type II 0.030
PLAUR plasminogen activator, urokinase receptor 0.029
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.025
PRDX2 peroxiredoxin 2 0.018
ICAM1 intercellular adhesion molecule 1 0.016
IL1B interleukin 1, beta 0.014
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.014
RXRA retinoid X receptor, alpha 0.014
TMEM161A transmembrane protein 161A 0.012
CCL20 chemokine (C-C motif) ligand 20 0.012
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.011
RARA retinoic acid receptor, alpha 0.011
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.851
Cav1 caveolin 1, caveolae protein 0.676
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.539
Csf1 colony stimulating factor 1 (macrophage) 0.514
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.436
Tgfb1 transforming growth factor, beta 1 0.431
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.377
Esr1 estrogen receptor 1 (alpha) 0.376
Lep leptin 0.209
Il10 interleukin 10 0.195
Lhx3 LIM homeobox protein 3 0.166
Rxra retinoid X receptor alpha 0.163
Tcf7 transcription factor 7, T-cell specific 0.150
Nos3 nitric oxide synthase 3, endothelial cell 0.133
Col1a1 collagen, type I, alpha 1 0.130
Tbx3 T-box 3 0.121
Lepr leptin receptor 0.120
Rag2 recombination activating gene 2 0.112
Foxn1 forkhead box N1 0.104
Insr insulin receptor 0.103
Bcl3 B-cell leukemia/lymphoma 3 0.101
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.093
Hils1 histone H1-like protein in spermatids 1 0.089
Nos2 nitric oxide synthase 2, inducible 0.084
Ctnnb1 catenin (cadherin associated protein), beta 1 0.076
Gcgr glucagon receptor 0.065
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.063
Hoxd11 homeobox D11 0.057
Il1a interleukin 1 alpha 0.056
Rgr retinal G protein coupled receptor 0.055
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.055
Msx2 homeobox, msh-like 2 0.050
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.048
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.046
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.045
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.042
Slc26a1 solute carrier family 26 (sulfate transporter), member 1 0.041
Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) 0.039
Abcc6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.038
Phlda2 pleckstrin homology-like domain, family A, member 2 0.038
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.037
Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 0.034
Klk1b4 kallikrein 1-related pepidase b4 0.034
D930020E02Rik RIKEN cDNA D930020E02 gene 0.034
Socs1 suppressor of cytokine signaling 1 0.034
Smad3 MAD homolog 3 (Drosophila) 0.034
Stk4 serine/threonine kinase 4 0.033
Kitl kit ligand 0.033
Sult1b1 sulfotransferase family 1B, member 1 0.033
Omp olfactory marker protein 0.032
Klk1b1 kallikrein 1-related peptidase b1 0.032
Rhox6 reproductive homeobox 6 0.032
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.032
Clcnka chloride channel Ka 0.032
Tlr2 toll-like receptor 2 0.031
Prph2 peripherin 2 0.031
Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 0.031
Pde6g phosphodiesterase 6G, cGMP-specific, rod, gamma 0.030
Vax1 ventral anterior homeobox containing gene 1 0.030
Rdh16 retinol dehydrogenase 16 0.030
Gata6 GATA binding protein 6 0.029
Rs1 retinoschisis (X-linked, juvenile) 1 (human) 0.029
Irs2 insulin receptor substrate 2 0.029
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.029
Thrb thyroid hormone receptor beta 0.029
Gcm1 glial cells missing homolog 1 (Drosophila) 0.028
Rxrg retinoid X receptor gamma 0.028
Hpd 4-hydroxyphenylpyruvic acid dioxygenase 0.027
Pou1f1 POU domain, class 1, transcription factor 1 0.026
Vav2 vav 2 oncogene 0.026
Pcsk4 proprotein convertase subtilisin/kexin type 4 0.026
Traf6 TNF receptor-associated factor 6 0.025
Tg thyroglobulin 0.024
Apoe apolipoprotein E 0.024
Ybx2 Y box protein 2 0.024
Tnp2 transition protein 2 0.024
Ghr growth hormone receptor 0.024
Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 0.023
Fam83f family with sequence similarity 83, member F 0.023
Slc5a11 solute carrier family 5 (sodium/glucose cotransporter), member 11 0.023
Adrb3 adrenergic receptor, beta 3 0.023
Tulp1 tubby like protein 1 0.023
Dvl3 dishevelled 3, dsh homolog (Drosophila) 0.022
Tnf tumor necrosis factor 0.022
Orm2 orosomucoid 2 0.022
Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.022
Igf1 insulin-like growth factor 1 0.022
Pla2g10 phospholipase A2, group X 0.021
Ang2 angiogenin, ribonuclease A family, member 2 0.021
Foxd2 forkhead box D2 0.021
Slc34a3 solute carrier family 34 (sodium phosphate), member 3 0.021
Psca prostate stem cell antigen 0.021
Prlr prolactin receptor 0.021
Amh anti-Mullerian hormone 0.021
Lrp5 low density lipoprotein receptor-related protein 5 0.021
Fam20c family with sequence similarity 20, member C 0.020
Wisp1 WNT1 inducible signaling pathway protein 1 0.020
Dmgdh dimethylglycine dehydrogenase precursor 0.020
Mep1b meprin 1 beta 0.020
Otp orthopedia homolog (Drosophila) 0.020
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism