The network for 'regulation of response to stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.994
vab-3 Protein VAB-3 0.949
unc-9 Protein UNC-9 0.834
par-5 Protein PAR-5 0.818
sax-3 Protein SAX-3 0.785
lit-1 Protein LIT-1 0.774
pha-4 Protein PHA-4 0.753
eps-8 Protein EPS-8 0.752
unc-40 Protein UNC-40 0.722
ida-1 Protein IDA-1 0.719
unc-43 Protein UNC-43 0.620
dim-1 Protein DIM-1 0.593
teg-4 Protein TEG-4 0.578
K10D6.4 Protein K10D6.4 0.563
unc-62 Protein UNC-62 0.559
sgn-1 Protein SGN-1 0.553
che-3 Protein CHE-3 0.533
bar-1 Protein BAR-1 0.522
atn-1 Protein ATN-1 0.518
nlg-1 Protein NLG-1 0.517
acs-4 Protein ACS-4 0.511
soc-2 Protein SOC-2 0.509
daf-14 Protein DAF-14 0.501
lin-25 Protein LIN-25 0.499
pes-7 Protein PES-7 0.489
itr-1 Protein ITR-1 0.489
csn-5 Protein CSN-5 0.477
plc-1 Protein PLC-1 0.471
pkg-1 Protein PKG-1 0.464
pry-1 Protein PRY-1 0.435
sng-1 Protein SNG-1 0.424
bir-1 Protein BIR-1 0.423
ten-1 Protein TEN-1 0.423
eor-2 Protein EOR-2 0.415
lev-8 Protein LEV-8 0.409
alp-1 Protein ALP-1 0.406
swan-2 Protein SWAN-2 0.404
mpz-2 Protein MPZ-2 0.400
ifd-1 Protein IFD-1 0.399
let-60 Protein LET-60 0.399
egl-27 Protein EGL-27 0.396
mig-5 Protein MIG-5 0.391
mat-3 Protein MAT-3 0.390
alx-1 Protein ALX-1 0.376
odr-3 Protein ODR-3 0.376
sma-1 Protein SMA-1 0.374
let-607 Protein LET-607 0.373
hmp-2 Protein HMP-2 0.372
daf-12 Protein DAF-12 0.366
F45E4.3 Protein F45E4.3 0.363
dpy-31 Protein DPY-31 0.361
akt-1 Protein AKT-1 0.357
unc-32 Protein UNC-32 0.357
lag-1 Protein LAG-1 0.356
gar-3 Protein GAR-3 0.352
inx-13 Protein INX-13 0.350
mig-2 Protein MIG-2 0.348
frm-7 Protein FRM-7 0.341
osm-5 Protein OSM-5 0.337
msp-55 Protein MSP-55 0.336
skn-1 Protein SKN-1 0.335
unc-52 Protein UNC-52 0.335
nipi-3 Protein NIPI-3 0.334
C14B9.2 Protein C14B9.2 0.333
daf-6 Protein DAF-6 0.332
daf-19 Protein DAF-19 0.331
apr-1 Protein APR-1 0.330
sup-12 Protein SUP-12 0.330
ehbp-1 Protein EHBP-1 0.328
sad-1 Protein SAD-1 0.323
C05D10.4 Protein C05D10.4 0.323
CELE_F14E5.2 Protein F14E5.2 0.322
che-2 Protein CHE-2 0.322
T28F4.1 Protein T28F4.1 0.320
F59A3.4 Protein F59A3.4 0.317
mom-2 Protein MOM-2 0.316
C54E4.2 Protein C54E4.2 0.315
ubr-1 Protein UBR-1 0.315
goa-1 Protein GOA-1 0.314
let-418 Protein LET-418 0.314
eor-1 Protein EOR-1 0.312
mec-2 Protein MEC-2 0.310
npp-7 Protein NPP-7 0.308
egl-13 Protein EGL-13 0.308
daf-11 Protein DAF-11 0.306
mig-38 Protein MIG-38 0.306
scd-1 Protein SCD-1 0.300
C13F10.4 Protein C13F10.4 0.300
K06A9.1 Protein K06A9.1 0.300
pal-1 Protein PAL-1 0.299
ceh-44 Protein CEH-44 0.295
gld-1 Protein GLD-1 0.295
smp-1 Protein SMP-1 0.292
lin-17 Protein LIN-17 0.291
kin-4 Protein KIN-4 0.290
sea-2 Protein SEA-2 0.289
lev-11 Protein LEV-11 0.287
flt-1 Protein FLT-1 0.285
nhr-45 Protein NHR-45 0.284
unc-7 Protein UNC-7 0.283
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Danio rerio
Name Description Probability Func Analog Organism
chd chordin 0.999
ntla no tail a 0.998
gli2a GLI-Kruppel family member GLI2a 0.994
dld deltaD 0.994
ndr2 nodal-related 2 0.988
gli1 GLI-Kruppel family member 1 0.987
crabp2a cellular retinoic acid binding protein 2, a 0.982
efnb2a ephrin B2a 0.966
tbx6 T-box gene 6 0.966
irx3a iroquois homeobox protein 3a 0.961
pkd2 polycystic kidney disease 2 0.952
bmp2b bone morphogenetic protein 2b 0.945
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.944
flh floating head 0.944
wnt11 wingless-type MMTV integration site family, member 11 0.937
tll1 tolloid-like 1 0.922
wnt5b wingless-type MMTV integration site family, member 5b 0.920
twist1a twist1a 0.912
eomesa eomesodermin homolog a 0.907
fgf3 fibroblast growth factor 3 0.901
bmp4 bone morphogenetic protein 4 0.900
fn1 fibronectin 1 0.899
pax8 paired box gene 8 0.899
ascl1a achaete-scute complex-like 1a (Drosophila) 0.898
ntn1b netrin 1b 0.896
fgf8a fibroblast growth factor 8 a 0.892
shha sonic hedgehog a 0.879
dharma dharma 0.878
cyp26a1 cytochrome P450, subfamily XXVIA, polypeptide 1 0.876
lhx1a LIM homeobox 1a 0.874
tcf7l1a transcription factor 7-like 1a (T-cell specific, HMG-box) 0.863
dab1a disabled homolog 1a (Drosophila) 0.862
brd4 bromodomain containing 4 0.860
gpc4 glypican 4 0.858
dusp6 dual specificity phosphatase 6 0.858
id1 inhibitor of DNA binding 1 0.856
pea3 ETS-domain transcription factor pea3 0.855
pax2a paired box gene 2a 0.848
bmp2a bone morphogenetic protein 2a 0.844
bmp7a bone morphogenetic protein 7a 0.843
adra2a adrenergic, alpha-2A-, receptor 0.841
gro1 groucho 1 0.840
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.837
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.829
foxh1 forkhead box H1 0.822
pard6gb par-6 partitioning defective 6 homolog gamma B (C. elegans) 0.821
foxd3 forkhead box D3 0.819
epha4a eph receptor A4a 0.819
gata4 GATA-binding protein 4 0.817
cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.813
hmx1 H6 homeo box 1 0.811
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.786
spns2 spinster homolog 2 (Drosophila) 0.786
fli1a friend leukemia integration 1a 0.784
twist3 twist3 0.781
pou5f1 POU domain, class 5, transcription factor 1 0.777
dlc deltaC 0.771
ephb3a eph receptor B3a 0.768
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.768
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.759
ift88 intraflagellar transport 88 homolog 0.758
oep one-eyed pinhead 0.756
pcdh18b protocadherin 18b 0.755
sf3b1 splicing factor 3b, subunit 1 0.750
mc2r melanocortin 2 receptor 0.749
myog myogenin 0.747
axin1 axin 1 0.744
six3b sine oculis homeobox homolog 3b 0.743
amotl2a angiomotin like 2a 0.735
snai1b snail homolog 1b (Drosophila) 0.728
mt2 metallothionein 2 0.721
myf5 myogenic factor 5 0.721
dzip1 DAZ interacting protein 1 0.720
tp53 tumor protein p53 0.718
notch2 notch homolog 2 0.718
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.718
mapk1 mitogen-activated protein kinase 1 0.712
hes6 hairy and enhancer of split 6 (Drosophila) 0.708
fzd7a frizzled homolog 7a 0.705
lfng lunatic fringe homolog 0.698
gsc goosecoid 0.686
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.680
foxa2 forkhead box A2 0.674
wnt11r wingless-type MMTV integration site family, member 11, related 0.672
tgfb3 transforming growth factor, beta 3 0.672
disp1 dispatched homolog 1 (Drosophila) 0.668
fzd10 frizzled homolog 10 0.667
fras1 Fraser syndrome 1 0.667
dkk1b dickkopf 1b 0.666
bambia BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a 0.664
egr2b early growth response 2b 0.659
phox2b paired-like homeobox 2b 0.657
cdx4 caudal type homeo box transcription factor 4 0.656
supt5h suppressor of Ty 5 homolog (S. cerevisiae) 0.652
gata5 GATA-binding protein 5 0.646
tbx16 T-box gene 16 0.644
dcc deleted in colorectal carcinoma 0.638
rest RE1-silencing transcription factor 0.636
gro2 groucho 2 0.635
otpa orthopedia homolog a 0.634
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
SLT2 Slt2p 0.948
SHO1 Sho1p 0.778
FAR11 Far11p 0.771
FAR1 Far1p 0.729
TPK2 Tpk2p 0.726
VPS64 Vps64p 0.726
CLA4 Cla4p 0.660
TPK1 Tpk1p 0.627
RRI1 Rri1p 0.604
PSY2 Psy2p 0.603
SPT16 Spt16p 0.586
TOR1 Tor1p 0.556
SLG1 Slg1p 0.549
HOG1 Hog1p 0.545
PIL1 Pil1p 0.537
KSP1 Ksp1p 0.535
MYO5 Myo5p 0.529
RHO1 Rho1p 0.524
BCK1 Bck1p 0.519
YAK1 Yak1p 0.518
CDC55 Cdc55p 0.511
MKK1 Mkk1p 0.507
CTR9 Ctr9p 0.503
ERP4 Erp4p 0.499
AKL1 Akl1p 0.479
FAR8 Far8p 0.465
CKA1 Cka1p 0.444
MSN2 Msn2p 0.438
RIM101 Rim101p 0.433
MIG1 Mig1p 0.426
PTC1 Ptc1p 0.413
FAR3 Far3p 0.408
UBP15 Ubp15p 0.406
MYO3 Myo3p 0.378
KOG1 Kog1p 0.378
PRB1 Prb1p 0.365
CDC28 Cdc28p 0.363
FUS1 Fus1p 0.360
BBC1 Bbc1p 0.355
ATG4 Atg4p 0.349
BEM1 Bem1p 0.348
CRZ1 Crz1p 0.338
HSE1 Hse1p 0.338
ATG13 Atg13p 0.338
YOL087C hypothetical protein 0.338
VPS27 Vps27p 0.331
ALO1 Alo1p 0.325
YDJ1 Ydj1p 0.318
END3 End3p 0.314
RPN4 Rpn4p 0.302
SLA2 Sla2p 0.298
MKS1 Mks1p 0.296
STE5 Ste5p 0.293
NET1 Net1p 0.290
CDC25 Cdc25p 0.289
CHC1 Chc1p 0.275
STE11 Ste11p 0.270
PPZ1 Ppz1p 0.268
CDC24 Cdc24p 0.261
YOR1 Yor1p 0.256
MON1 Mon1p 0.255
RAD51 Rad51p 0.244
SSK1 Ssk1p 0.242
MBR1 Mbr1p 0.241
PBS2 Pbs2p 0.241
POL30 Pol30p 0.231
CDC34 Cdc34p 0.231
VAM7 Vam7p 0.230
MDS3 Mds3p 0.229
VAC8 Vac8p 0.229
RLM1 Rlm1p 0.228
EBS1 Ebs1p 0.227
STE18 Ste18p 0.222
ADR1 Adr1p 0.214
FUS3 Fus3p 0.214
SNT1 Snt1p 0.210
SET2 Set2p 0.208
SPA2 Spa2p 0.208
SSK2 Ssk2p 0.207
SSE1 Sse1p 0.204
TRS65 Trs65p 0.204
VPS4 Vps4p 0.202
EAF5 Eaf5p 0.202
SCP1 Scp1p 0.200
PAF1 Paf1p 0.195
PTP2 Ptp2p 0.195
HSV2 Hsv2p 0.195
HAL5 Hal5p 0.193
STE20 Ste20p 0.193
SIR4 Sir4p 0.193
ROM2 Rom2p 0.193
CNB1 Cnb1p 0.190
STE12 Ste12p 0.190
ENA5 Ena5p 0.187
SLX5 Slx5p 0.186
VPS20 Vps20p 0.181
SLZ1 Slz1p 0.181
STI1 Sti1p 0.178
RAD23 Rad23p 0.178
YPT1 Ypt1p 0.177