The network for 'regulation of glial cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of glial cell differentiation

Any process that modulates the frequency, rate or extent of glia cell differentiation.

Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
ascl1a achaete-scute complex-like 1a (Drosophila) 0.975
cdh2 cadherin 2, neuronal 0.972
dld deltaD 0.971
bmp2b bone morphogenetic protein 2b 0.942
isl1 islet1 0.690
dla deltaA 0.687
fgf8a fibroblast growth factor 8 a 0.655
her4.2 hairy-related 4.2 0.604
notch3 notch homolog 3 0.596
lhx1a LIM homeobox 1a 0.529
nkx2.2a NK2 transcription factor related 2a 0.528
sfrp5 secreted frizzled-related protein 5 0.519
pax2a paired box gene 2a 0.519
tbx1 T-box 1 0.498
dlx4b distal-less homeobox gene 4b 0.487
nkx6.1 NK6 transcription factor related, locus 1 (Drosophila) 0.482
dlc deltaC 0.480
osr1 odd-skipped related 1 (Drosophila) 0.469
smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.465
her12 hairy-related 12 0.431
pitx3 paired-like homeodomain transcription factor 3 0.426
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.425
flh floating head 0.425
efnb2a ephrin B2a 0.425
msxc muscle segment homeobox C 0.401
rarab retinoic acid receptor, alpha b 0.385
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.385
olig2 oligodendrocyte lineage transcription factor 2 0.375
lfng lunatic fringe homolog 0.363
nf1a neurofibromin 1a 0.351
dlx2a distal-less homeobox gene 2a 0.342
neurod neurogenic differentiation 0.335
lef1 lymphocyte enhancer binding factor 1 0.311
otpb orthopedia homolog b 0.305
dlx1a distal-less homeobox gene 1a 0.299
dnmt8 DNA (cytosine-5-)-methyltransferase 8 0.299
pax6b paired box gene 6b 0.298
gli1 GLI-Kruppel family member 1 0.292
pcdh17 protocadherin 17 0.290
notch1a notch homolog 1a 0.287
rspo3 R-spondin 3 homolog (Xenopus laevis) 0.275
pax6a paired box gene 6a 0.274
foxd3 forkhead box D3 0.272
mnx1 motor neuron and pancreas homeobox 1 0.265
epha4a eph receptor A4a 0.261
ntla no tail a 0.259
shha sonic hedgehog a 0.255
ascl1b achaete-scute complex-like 1b (Drosophila) 0.249
gsc goosecoid 0.234
fabp11a fatty acid binding protein 11a 0.225
robo3 roundabout homolog 3 0.216
cdh1 cadherin 1, epithelial 0.214
cdkn1c cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.210
chd chordin 0.208
arx aristaless related homeobox 0.207
her15.1 hairy and enhancer of split-related 15.1 0.192
gli2a GLI-Kruppel family member GLI2a 0.191
snai1a snail homolog 1a (Drosophila) 0.188
tbx16 T-box gene 16 0.181
dlx4a distal-less homeobox gene 4a 0.179
sox3 SRY-box containing gene 3 0.176
foxa2 forkhead box A2 0.175
neurog1 neurogenin 1 0.170
vsx2 visual system homeobox 2 0.169
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.165
prox1 prospero-related homeobox gene 1 0.154
sox19a SRY-box containing gene 19a 0.153
barhl2 BarH-like 2 0.150
axin1 axin 1 0.150
pard6gb par-6 partitioning defective 6 homolog gamma B (C. elegans) 0.149
emx3 empty spiracles homeobox 3 0.148
sst1.1 somatostatin 1, tandem duplicate 1 0.146
plp1a proteolipid protein 1a 0.143
rfx2 regulatory factor X, 2 (influences HLA class II expression) 0.143
rbpms2 RNA binding protein with multiple splicing 2 0.141
rasl11b RAS-like, family 11, member B 0.139
insm1a insulinoma-associated 1a 0.136
dlx6a distal-less homeobox gene 6a 0.131
myh11a myosin, heavy polypeptide 11, smooth muscle a 0.129
traf4a tnf receptor-associated factor 4a 0.129
sim1a single-minded homolog 1a (Drosophila) 0.125
jag2 jagged 2 0.120
acvr1l activin A receptor, type I like 0.118
sox2 SRY-box containing gene 2 0.118
aplnrb apelin receptor b 0.117
nr2f1b nuclear receptor subfamily 2, group F, member 1b 0.114
ilf2 interleukin enhancer binding factor 2 0.109
emx2 empty spiracles homeobox 2 0.108
sox19b SRY-box containing gene 19b 0.107
zic3 zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) 0.106
axin2 axin 2 (conductin, axil) 0.105
ryk receptor-like tyrosine kinase 0.105
ndrg4 N-myc downstream regulated gene 4 0.105
prdm1a PR domain containing 1a, with ZNF domain 0.104
meis2.2 myeloid ecotropic viral integration site 2.2 0.102
gdf6a growth differentiation factor 6a 0.102
her6 hairy-related 6 0.101
slc17a6b solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b 0.101
sp8b sp8 transcription factor b 0.101
foxa3 forkhead box A3 0.100
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Drosophila melanogaster
Name Description Probability Func Analog Organism
E(spl) Enhancer of split 0.982
HLHmdelta E(spl) region transcript mdelta 0.946
HLHm7 E(spl) region transcript m7 0.939
wg wingless 0.935
N Notch 0.922
HLHmgamma E(spl) region transcript mgamma 0.890
HLHmbeta E(spl) region transcript mbeta 0.746
malpha E(spl) region transcript malpha 0.551
HLHm3 E(spl) region transcript m3 0.534
HLHm5 E(spl) region transcript m5 0.526
ed echinoid 0.467
ac achaete 0.434
tkv thickveins 0.407
klu klumpfuss 0.388
en engrailed 0.383
m2 E(spl) region transcript m2 0.323
ci cubitus interruptus 0.307
arm armadillo 0.299
Ras85D Ras oncogene at 85D 0.290
m4 E(spl) region transcript m4 0.256
Tom Twin of m4 0.251
sc scute 0.203
Egfr Epidermal growth factor receptor 0.199
gcm glial cells missing 0.178
hh hedgehog 0.155
esg escargot 0.153
stumps CG31317 gene product from transcript CG31317-RC 0.152
spi spitz 0.141
H Hairless 0.135
fng fringe 0.126
bnl branchless 0.120
noc no ocelli 0.108
tan tantalus 0.102
put punt 0.101
smo smoothened 0.101
ptc patched 0.094
dock dreadlocks 0.092
nej nejire 0.091
Su(H) Suppressor of Hairless 0.087
ase asense 0.082
CG12424 CG12424 gene product from transcript CG12424-RC 0.082
dpp decapentaplegic 0.081
Ephrin CG1862 gene product from transcript CG1862-RA 0.069
CG4699 CG4699 gene product from transcript CG4699-RJ 0.067
trx trithorax 0.063
kay kayak 0.060
salm spalt major 0.060
su(f) suppressor of forked 0.060
sd scalloped 0.060
Nrx-IV Neurexin IV 0.059
Mad Mothers against dpp 0.057
hth homothorax 0.056
Fas1 Fasciclin 1 0.055
CtBP C-terminal Binding Protein 0.055
Grip75 CG6176 gene product from transcript CG6176-RA 0.054
ato atonal 0.053
pnt pointed 0.052
BobA Brother of Bearded A 0.050
inv invected 0.047
Dl Delta 0.046
numb CG3779 gene product from transcript CG3779-RB 0.045
Smox Smad on X 0.044
ab abrupt 0.044
wun wunen 0.043
mys myospheroid 0.043
hrg hiiragi 0.042
jeb jelly belly 0.042
gro groucho 0.040
ttk tramtrack 0.040
kuz kuzbanian 0.040
aop anterior open 0.040
slp1 sloppy paired 1 0.040
tap target of Poxn 0.037
Ser Serrate 0.034
CycJ Cyclin J 0.032
ss spineless 0.031
fz2 frizzled 2 0.031
nrv2 nervana 2 0.030
eg eagle 0.030
rpr reaper 0.028
Stat92E Signal-transducer and activator of transcription protein at 92E 0.028
twi twist 0.028
CG2926 CG2926 gene product from transcript CG2926-RA 0.027
ASPP Ankyrin-repeat, SH3-domain, and Proline-rich-region containing Protein 0.027
Lac Lachesin 0.027
eya eyes absent 0.026
babo baboon 0.026
CG11347 CG11347 gene product from transcript CG11347-RE 0.026
mol moladietz 0.025
Poxn Pox neuro 0.025
Akt1 CG4006 gene product from transcript CG4006-RA 0.024
dsh dishevelled 0.024
sli slit 0.024
Wnt2 Wnt oncogene analog 2 0.024
repo reversed polarity 0.024
hiw highwire 0.023
Nrt Neurotactin 0.023
myoglianin CG1838 gene product from transcript CG1838-RD 0.023
pros prospero 0.023
ft fat 0.022
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Homo sapiens
Name Description Probability Func Analog Organism
PLAU plasminogen activator, urokinase 0.759
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.664
BMPR1A bone morphogenetic protein receptor, type IA 0.512
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.503
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.424
IL1R1 interleukin 1 receptor, type I 0.421
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.413
JAG1 jagged 1 0.306
DNM1 dynamin 1 0.301
RIN3 Ras and Rab interactor 3 0.292
SYNJ1 synaptojanin 1 0.290
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.212
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.182
KRT8 keratin 8 0.175
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.169
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.162
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.160
PSEN1 presenilin 1 0.154
NOTCH3 notch 3 0.143
BMP7 bone morphogenetic protein 7 0.138
FGF1 fibroblast growth factor 1 (acidic) 0.131
CDC14B CDC14 cell division cycle 14 homolog B (S. cerevisiae) 0.121
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.113
PLAT plasminogen activator, tissue 0.111
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.108
SIRT1 sirtuin 1 0.107
ALB albumin 0.106
BMP2 bone morphogenetic protein 2 0.105
IL1RAP interleukin 1 receptor accessory protein 0.104
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.099
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.098
JUP junction plakoglobin 0.097
EGR1 early growth response 1 0.094
MAML1 mastermind-like 1 (Drosophila) 0.093
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.089
MAX MYC associated factor X 0.089
GRB2 growth factor receptor-bound protein 2 0.086
EFTUD2 elongation factor Tu GTP binding domain containing 2 0.083
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.083
JAK1 Janus kinase 1 0.082
JAK2 Janus kinase 2 0.076
SNAP23 synaptosomal-associated protein, 23kDa 0.076
FSTL1 follistatin-like 1 0.076
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.073
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.070
TNRC6C trinucleotide repeat containing 6C 0.070
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 0.068
TCF4 transcription factor 4 0.067
AR androgen receptor 0.067
F3 coagulation factor III (thromboplastin, tissue factor) 0.066
GLIS2 GLIS family zinc finger 2 0.066
SNX9 sorting nexin 9 0.064
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.064
TP53 tumor protein p53 0.064
FGA fibrinogen alpha chain 0.063
APP amyloid beta (A4) precursor protein 0.061
REPS2 RALBP1 associated Eps domain containing 2 0.061
YAP1 Yes-associated protein 1 0.059
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.058
ZFYVE9 zinc finger, FYVE domain containing 9 0.058
FBXW7 F-box and WD repeat domain containing 7 0.056
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.053
HDAC6 histone deacetylase 6 0.052
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.052
MYOD1 myogenic differentiation 1 0.050
FGFR2 fibroblast growth factor receptor 2 0.050
APC adenomatous polyposis coli 0.048
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.048
SF3A1 splicing factor 3a, subunit 1, 120kDa 0.047
HIST1H4F histone cluster 1, H4f 0.047
BBS10 Bardet-Biedl syndrome 10 0.046
OLIG2 oligodendrocyte lineage transcription factor 2 0.045
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.045
WWOX WW domain containing oxidoreductase 0.044
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.043
ACTN1 actinin, alpha 1 0.043
TAL1 T-cell acute lymphocytic leukemia 1 0.042
LIFR leukemia inhibitory factor receptor alpha 0.042
KAT2B K(lysine) acetyltransferase 2B 0.041
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.040
TNIK TRAF2 and NCK interacting kinase 0.040
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.040
IL6R interleukin 6 receptor 0.040
NOG noggin 0.040
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.040
DLL3 delta-like 3 (Drosophila) 0.039
IL1RN interleukin 1 receptor antagonist 0.039
BDNF brain-derived neurotrophic factor 0.039
ORM1 orosomucoid 1 0.037
EP300 E1A binding protein p300 0.037
AXIN1 axin 1 0.037
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.037
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.037
ZYX zyxin 0.036
MUC1 mucin 1, cell surface associated 0.035
TGFB1 transforming growth factor, beta 1 0.035
CCR5 chemokine (C-C motif) receptor 5 0.035
FERMT2 fermitin family member 2 0.035
MAPK14 mitogen-activated protein kinase 14 0.034
CTGF connective tissue growth factor 0.034
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Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Pax3 paired box gene 3 0.999
Sox9 SRY-box containing gene 9 0.999
Msx1 homeobox, msh-like 1 0.997
Otx2 orthodenticle homolog 2 (Drosophila) 0.993
Gli3 GLI-Kruppel family member GLI3 0.993
Hand2 heart and neural crest derivatives expressed transcript 2 0.993
Foxc1 forkhead box C1 0.991
Fgfr1 fibroblast growth factor receptor 1 0.983
Ctnnb1 catenin (cadherin associated protein), beta 1 0.983
Eya1 eyes absent 1 homolog (Drosophila) 0.982
Tgfb2 transforming growth factor, beta 2 0.982
Dlx5 distal-less homeobox 5 0.978
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.976
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.966
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.964
Chrd chordin 0.963
Lef1 lymphoid enhancer binding factor 1 0.960
Fgf8 fibroblast growth factor 8 0.958
Emx1 empty spiracles homolog 1 (Drosophila) 0.957
Prrx1 paired related homeobox 1 0.954
Gli2 GLI-Kruppel family member GLI2 0.949
Ltb lymphotoxin B 0.949
Isl1 ISL1 transcription factor, LIM/homeodomain 0.946
Hand1 heart and neural crest derivatives expressed transcript 1 0.945
Efnb2 ephrin B2 0.937
Foxc2 forkhead box C2 0.932
Gsc goosecoid homeobox 0.924
Notch1 Notch gene homolog 1 (Drosophila) 0.919
Sox2 SRY-box containing gene 2 0.907
Rarb retinoic acid receptor, beta 0.903
Tbx1 T-box 1 0.903
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.896
Gata4 GATA binding protein 4 0.885
Rarg retinoic acid receptor, gamma 0.878
Id3 inhibitor of DNA binding 3 0.872
Dlx2 distal-less homeobox 2 0.847
Tcfap2a transcription factor AP-2, alpha 0.800
Meox2 mesenchyme homeobox 2 0.796
Rara retinoic acid receptor, alpha 0.795
Hoxa2 homeobox A2 0.790
Bmp4 bone morphogenetic protein 4 0.786
Ret ret proto-oncogene 0.786
Ccr2 chemokine (C-C motif) receptor 2 0.725
Smo smoothened homolog (Drosophila) 0.708
Cd44 CD44 antigen 0.705
Dlx1 distal-less homeobox 1 0.670
Nodal nodal 0.659
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.646
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.644
Pax9 paired box gene 9 0.637
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.636
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.631
Dcc deleted in colorectal carcinoma 0.629
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.606
Runx2 runt related transcription factor 2 0.601
Acvr1 activin A receptor, type 1 0.590
Oprd1 opioid receptor, delta 1 0.587
Dlx6 distal-less homeobox 6 0.578
Sox4 SRY-box containing gene 4 0.577
Ptch1 patched homolog 1 0.573
Pbx1 pre B-cell leukemia transcription factor 1 0.568
Hes1 hairy and enhancer of split 1 (Drosophila) 0.568
Vegfa vascular endothelial growth factor A 0.549
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.542
Id1 inhibitor of DNA binding 1 0.537
Pax6 paired box gene 6 0.531
Bmp7 bone morphogenetic protein 7 0.530
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.524
Fgfr3 fibroblast growth factor receptor 3 0.521
Psen1 presenilin 1 0.513
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.505
Col2a1 collagen, type II, alpha 1 0.504
Hmx1 H6 homeobox 1 0.495
Alx4 aristaless-like homeobox 4 0.493
Jag1 jagged 1 0.480
Insm1 insulinoma-associated 1 0.477
Ntf3 neurotrophin 3 0.472
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.470
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.464
Sall3 sal-like 3 (Drosophila) 0.458
Sox11 SRY-box containing gene 11 0.450
Emx2 empty spiracles homolog 2 (Drosophila) 0.450
Bmp2 bone morphogenetic protein 2 0.434
Trp53 transformation related protein 53 0.433
Zeb1 zinc finger E-box binding homeobox 1 0.429
Ednra endothelin receptor type A 0.422
Foxg1 forkhead box G1 0.420
Cckbr cholecystokinin B receptor 0.419
Id4 inhibitor of DNA binding 4 0.409
Gsx1 GS homeobox 1 0.409
Pax8 paired box gene 8 0.408
Nog noggin 0.391
Hoxa3 homeobox A3 0.388
Neurog2 neurogenin 2 0.384
Phox2b paired-like homeobox 2b 0.384
Sox10 SRY-box containing gene 10 0.380
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.379
Chl1 cell adhesion molecule with homology to L1CAM 0.373
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Rattus norvegicus
Name Description Probability Func Analog Organism
Junb jun B proto-oncogene 0.014
Fos FBJ osteosarcoma oncogene 0.011
Egr1 early growth response 1 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism