The network for 'positive regulation of multicellular organism growth' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of multicellular organism growth

Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.

Caenorhabditis elegans
Name Description Probability Func Analog Organism
col-157 Protein COL-157 0.488
atn-1 Protein ATN-1 0.407
hlh-2 Protein HLH-2 0.370
nhr-2 Protein NHR-2 0.349
egl-18 Protein EGL-18 0.326
swsn-2.1 Protein SWSN-2.1 0.310
inx-12 Protein INX-12 0.298
ZK84.1 Protein ZK84.1 0.290
lrp-1 Protein LRP-1 0.282
sams-1 Protein SAMS-1 0.277
daf-4 Protein DAF-4 0.277
mes-3 Protein MES-3 0.269
anc-1 Protein ANC-1 0.261
wrt-6 Protein WRT-6 0.251
itx-1 Protein ITX-1 0.249
col-34 Protein COL-34 0.247
vha-10 Protein VHA-10 0.245
dpyd-1 Protein DPYD-1 0.241
rol-6 Protein ROL-6 0.239
C34E7.4 Protein C34E7.4 0.238
kgb-1 Protein KGB-1 0.223
plc-1 Protein PLC-1 0.222
rol-8 Protein ROL-8 0.217
hum-5 Protein HUM-5 0.212
ifb-2 Protein IFB-2 0.211
twk-25 Protein TWK-25 0.211
set-2 Protein SET-2 0.207
rpm-1 Protein RPM-1 0.207
glp-1 Protein GLP-1 0.205
spe-5 Protein SPE-5 0.202
D2085.3 Protein D2085.3 0.201
sdz-28 Protein SDZ-28 0.200
CELE_W09C5.1 Protein W09C5.1 0.200
Y17G7B.18 Protein Y17G7B.18 0.199
T20H4.5 Protein T20H4.5 0.197
col-98 Protein COL-98 0.197
pha-4 Protein PHA-4 0.197
daf-14 Protein DAF-14 0.192
col-103 Protein COL-103 0.192
edc-3 Protein EDC-3 0.192
msp-36 Protein MSP-36 0.190
T01C8.2 Protein T01C8.2 0.189
lin-66 Protein LIN-66 0.189
fasn-1 Protein FASN-1 0.189
sams-3 Protein SAMS-3 0.187
dcn-1 Protein DCN-1 0.186
tiar-1 Protein TIAR-1 0.186
col-119 Protein COL-119 0.186
bec-1 Protein BEC-1 0.185
K10D2.5 Protein K10D2.5 0.185
col-73 Protein COL-73 0.183
dpy-13 Protein DPY-13 0.182
skr-14 Protein SKR-14 0.181
cct-2 Protein CCT-2 0.180
col-166 Protein COL-166 0.180
dpy-6 Protein DPY-6 0.180
col-133 Protein COL-133 0.178
Y59H11AM.1 Protein Y59H11AM.1 0.178
vha-8 Protein VHA-8 0.175
inx-5 Protein INX-5 0.174
saps-1 Protein SAPS-1 0.174
mlc-2 Protein MLC-2 0.174
ttm-4 Protein TTM-4 0.172
npp-7 Protein NPP-7 0.171
F35C12.3 Protein F35C12.3 0.171
lbp-6 Protein LBP-6 0.170
col-154 Protein COL-154 0.170
apl-1 Protein APL-1 0.170
swsn-1 Protein SWSN-1 0.170
unc-62 Protein UNC-62 0.170
col-140 Protein COL-140 0.170
bah-1 Protein BAH-1 0.170
col-17 Protein COL-17 0.169
unc-29 Protein UNC-29 0.168
pac-1 Protein PAC-1 0.168
abl-1 Protein ABL-1 0.168
col-181 Protein COL-181 0.167
acs-4 Protein ACS-4 0.167
msp-10 Protein MSP-10 0.166
dnj-9 Protein DNJ-9 0.165
pqn-53 Protein PQN-53 0.164
col-101 Protein COL-101 0.164
cpsf-1 Protein CPSF-1 0.163
noah-1 Protein NOAH-1 0.163
msp-64 Protein MSP-64 0.162
top-1 Protein TOP-1 0.162
sma-9 Protein SMA-9 0.161
col-159 Protein COL-159 0.160
pyr-1 Protein PYR-1 0.160
vps-16 Protein VPS-16 0.160
W03D8.9 Protein W03D8.9 0.159
col-8 Protein COL-8 0.159
unc-73 Protein UNC-73 0.158
col-65 Protein COL-65 0.158
col-93 Protein COL-93 0.158
dlk-1 Protein DLK-1 0.158
eif-3.C Protein EIF-3.C 0.157
col-84 Protein COL-84 0.156
aqp-2 Protein AQP-2 0.155
cacn-1 Protein CACN-1 0.155
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Ras85D Ras oncogene at 85D 0.970
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.892
Rheb CG1081 gene product from transcript CG1081-RA 0.864
SNF1A SNF1A/AMP-activated protein kinase 0.864
Lnk CG17367 gene product from transcript CG17367-RC 0.839
Stat92E Signal-transducer and activator of transcription protein at 92E 0.637
egl egalitarian 0.626
gig gigas 0.624
Tor Target of rapamycin 0.617
Ilp2 Insulin-like peptide 2 0.606
ebi CG4063 gene product from transcript CG4063-RA 0.474
chico CG5686 gene product from transcript CG5686-RB 0.459
Ide Insulin degrading metalloproteinase 0.409
Ilp5 Insulin-like peptide 5 0.398
sax saxophone 0.386
Pk61C Protein kinase 61C 0.337
sxc super sex combs 0.317
fkh fork head 0.289
phl pole hole 0.282
Smox Smad on X 0.281
Pten CG5671 gene product from transcript CG5671-RB 0.274
eIF-4E Eukaryotic initiation factor 4E 0.270
Tip60 CG6121 gene product from transcript CG6121-RA 0.258
arm armadillo 0.247
grim CG4345 gene product from transcript CG4345-RA 0.242
Ilp3 Insulin-like peptide 3 0.230
ctp cut up 0.229
Cg25C Collagen type IV 0.218
drk downstream of receptor kinase 0.212
Hcf Host cell factor 0.209
foxo forkhead box, sub-group O 0.208
Ilp6 Insulin-like peptide 6 0.203
eIF-5A CG3186 gene product from transcript CG3186-RA 0.188
put punt 0.173
Hsc70-4 Heat shock protein cognate 4 0.166
FK506-bp2 FK506-binding protein 2 0.163
Hsf Heat shock factor 0.160
S6k RPS6-p70-protein kinase 0.158
Tak1 TGF-beta activated kinase 1 0.157
sNPF-R short neuropeptide F receptor 0.148
pico CG11940 gene product from transcript CG11940-RA 0.146
nos nanos 0.143
Sir2 CG5216 gene product from transcript CG5216-RA 0.138
lap like-AP180 0.130
Vmat Vesicular monoamine transporter 0.125
rpr reaper 0.122
tkv thickveins 0.112
Ulp1 CG12359 gene product from transcript CG12359-RA 0.111
cher cheerio 0.111
CycE Cyclin E 0.107
Egfr Epidermal growth factor receptor 0.105
Su(z)12 CG8013 gene product from transcript CG8013-RA 0.104
Pka-R1 cAMP-dependent protein kinase R1 0.099
ras raspberry 0.095
Mad Mothers against dpp 0.092
RanGap Ran GTPase activating protein 0.091
cdm cadmus 0.089
stan starry night 0.082
CG14482 CG14482 gene product from transcript CG14482-RA 0.079
Top2 Topoisomerase 2 0.076
sNPF short neuropeptide F precursor 0.075
Akt1 CG4006 gene product from transcript CG4006-RA 0.073
Stim Stromal interaction molecule 0.070
krz kurtz 0.070
Vha36 CG8186 gene product from transcript CG8186-RA 0.070
rl rolled 0.070
slik Sterile20-like kinase 0.068
myoglianin CG1838 gene product from transcript CG1838-RD 0.066
CG1970 CG1970 gene product from transcript CG1970-RA 0.065
dm diminutive 0.065
Eip63E Ecdysone-induced protein 63E 0.065
CG15881 CG15881 gene product from transcript CG15881-RB 0.065
CG9139 CG9139 gene product from transcript CG9139-RA 0.061
Atg18 Autophagy-specific gene 18 0.057
dia diaphanous 0.057
Lis-1 Lissencephaly-1 0.057
CG14270 CG14270 gene product from transcript CG14270-RA 0.056
ci cubitus interruptus 0.056
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.056
pelo pelota 0.055
uif uninflatable 0.054
Btk29A Btk family kinase at 29A 0.054
btl breathless 0.053
asf1 anti-silencing factor 1 0.052
dib disembodied 0.052
dpp decapentaplegic 0.052
Gr28b Gustatory receptor 28b 0.049
Atg8a Autophagy-specific gene 8a 0.049
Vha13 Vacuolar H[+] ATPase G-subunit 0.049
Pde1c Phosphodiesterase 1c 0.048
Nf1 Neurofibromin 1 0.048
BM-40-SPARC CG6378 gene product from transcript CG6378-RA 0.048
mtTFB2 mitochondrial transcription factor B2 0.048
EcR Ecdysone receptor 0.048
ari-1 ariadne 0.047
Prp8 pre-mRNA processing factor 8 0.047
smo smoothened 0.047
svp seven up 0.046
mtt mangetout 0.046
Pkn Protein kinase related to protein kinase N 0.045
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Homo sapiens
Name Description Probability Func Analog Organism
SMAD3 SMAD family member 3 0.746
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.628
INSR insulin receptor 0.441
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.275
CDC6 cell division cycle 6 homolog (S. cerevisiae) 0.211
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.198
CBX3 chromobox homolog 3 0.172
H2AFX H2A histone family, member X 0.172
TNRC6A trinucleotide repeat containing 6A 0.170
TRIM28 tripartite motif containing 28 0.148
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.141
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.136
IGF1R insulin-like growth factor 1 receptor 0.105
IRS1 insulin receptor substrate 1 0.104
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.102
PDIA3 protein disulfide isomerase family A, member 3 0.092
RPL27 ribosomal protein L27 0.090
CREB1 cAMP responsive element binding protein 1 0.085
MBNL1 muscleblind-like (Drosophila) 0.083
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.080
CREBBP CREB binding protein 0.079
GH1 growth hormone 1 0.078
EGFR epidermal growth factor receptor 0.075
RPL37A ribosomal protein L37a 0.073
FKBP1A FK506 binding protein 1A, 12kDa 0.062
SMAD2 SMAD family member 2 0.060
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.056
TUFM Tu translation elongation factor, mitochondrial 0.054
RPL36A ribosomal protein L36a 0.048
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.046
EP300 E1A binding protein p300 0.045
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.043
SP1 Sp1 transcription factor 0.043
MCM5 minichromosome maintenance complex component 5 0.043
RPL32 ribosomal protein L32 0.042
RPL34 ribosomal protein L34 0.041
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.041
MTA1 metastasis associated 1 0.039
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.039
PDIA4 protein disulfide isomerase family A, member 4 0.039
EIF3H eukaryotic translation initiation factor 3, subunit H 0.036
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.035
ZFX zinc finger protein, X-linked 0.035
ADNP activity-dependent neuroprotector homeobox 0.035
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.034
EIF2C2 eukaryotic translation initiation factor 2C, 2 0.034
RPL41 ribosomal protein L41 0.033
BAD BCL2-associated agonist of cell death 0.033
PRDX4 peroxiredoxin 4 0.032
AR androgen receptor 0.032
PRDX1 peroxiredoxin 1 0.031
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.031
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.028
NOP58 NOP58 ribonucleoprotein homolog (yeast) 0.028
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.028
ELP3 elongation protein 3 homolog (S. cerevisiae) 0.027
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 0.026
NCOA6 nuclear receptor coactivator 6 0.026
RAN RAN, member RAS oncogene family 0.026
HIPK2 homeodomain interacting protein kinase 2 0.026
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.025
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.025
TP53 tumor protein p53 0.024
MAPK1 mitogen-activated protein kinase 1 0.024
SMAD7 SMAD family member 7 0.024
RPS25 ribosomal protein S25 0.023
EIF4B eukaryotic translation initiation factor 4B 0.022
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.022
SMAD4 SMAD family member 4 0.022
CTR9 Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.022
RPL30 ribosomal protein L30 0.021
SNTA1 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) 0.020
EEF1B2 eukaryotic translation elongation factor 1 beta 2 0.020
PABPC1 poly(A) binding protein, cytoplasmic 1 0.020
PEX14 peroxisomal biogenesis factor 14 0.019
BCL2L1 BCL2-like 1 0.019
GRB10 growth factor receptor-bound protein 10 0.019
CNOT1 CCR4-NOT transcription complex, subunit 1 0.018
PAPOLA poly(A) polymerase alpha 0.018
PAX3 paired box 3 0.018
DDX5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 0.018
NME1 non-metastatic cells 1, protein (NM23A) expressed in 0.017
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.017
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.017
SKIL SKI-like oncogene 0.016
MCM2 minichromosome maintenance complex component 2 0.016
SNIP1 Smad nuclear interacting protein 1 0.016
MANF mesencephalic astrocyte-derived neurotrophic factor 0.016
SF1 splicing factor 1 0.016
CRH corticotropin releasing hormone 0.015
ILF3 interleukin enhancer binding factor 3, 90kDa 0.015
TXN thioredoxin 0.015
PGK1 phosphoglycerate kinase 1 0.015
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.015
MED15 mediator complex subunit 15 0.015
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.015
EIF2C1 eukaryotic translation initiation factor 2C, 1 0.015
PTPRN protein tyrosine phosphatase, receptor type, N 0.015
CARM1 coactivator-associated arginine methyltransferase 1 0.014
ADAM10 ADAM metallopeptidase domain 10 0.014
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism