The network for 'regulation of apoptotic signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of apoptotic signaling pathway

Any process that modulates the frequency, rate or extent of apoptotic signaling pathway.

Caenorhabditis elegans
Name Description Probability Func Analog Organism
par-5 Protein PAR-5 0.098
ess-2 Protein ESS-2 0.086
crt-1 Protein CRT-1 0.078
tbb-2 Protein TBB-2 0.076
bar-1 Protein BAR-1 0.073
eef-1A.1 Protein EEF-1A.1 0.069
let-60 Protein LET-60 0.061
gdi-1 Protein GDI-1 0.059
daf-21 Protein DAF-21 0.059
egl-18 Protein EGL-18 0.056
sma-6 Protein SMA-6 0.054
itr-1 Protein ITR-1 0.053
F36D4.5 Protein F36D4.5 0.051
tag-343 Protein TAG-343 0.051
inx-13 Protein INX-13 0.051
hsp-4 Protein HSP-4 0.049
T08B2.7 Protein T08B2.7 0.049
ant-1.1 Protein ANT-1.1 0.048
eor-1 Protein EOR-1 0.047
vha-15 Protein VHA-15 0.046
icd-1 Protein ICD-1 0.045
mig-2 Protein MIG-2 0.045
eef-1G Protein EEF-1G 0.045
act-3 Protein ACT-3 0.044
imp-2 Protein IMP-2 0.044
rpl-5 Protein RPL-5 0.043
pph-6 Protein PPH-6 0.043
dnc-1 Protein DNC-1 0.043
atn-1 Protein ATN-1 0.043
CELE_W03F9.10 Protein W03F9.10 0.043
hsp-3 Protein HSP-3 0.042
F55C12.5 Protein F55C12.5 0.042
zyg-8 Protein ZYG-8 0.041
swan-2 Protein SWAN-2 0.040
pry-1 Protein PRY-1 0.040
mat-3 Protein MAT-3 0.040
rps-2 Protein RPS-2 0.040
C39D10.7 Protein C39D10.7 0.039
zyg-1 Protein ZYG-1 0.039
rpl-24.1 Protein RPL-24.1 0.039
let-756 Protein LET-756 0.039
CELE_F14E5.2 Protein F14E5.2 0.038
nhr-49 Protein NHR-49 0.038
ifg-1 Protein IFG-1 0.038
soc-2 Protein SOC-2 0.038
ztf-17 Protein ZTF-17 0.038
gei-4 Protein GEI-4 0.038
arf-3 Protein ARF-3 0.038
pat-2 Protein PAT-2 0.038
B0272.3 Protein B0272.3 0.038
pmk-1 Protein PMK-1 0.038
prdx-2 Protein PRDX-2 0.038
lin-35 Protein LIN-35 0.038
egl-30 Protein EGL-30 0.037
lig-4 Protein LIG-4 0.037
C26E1.2 Protein C26E1.2 0.037
aap-1 Protein AAP-1 0.037
C25F6.1 Protein C25F6.1 0.036
kin-3 Protein KIN-3 0.036
F22H10.3 Protein F22H10.3 0.036
fli-1 Protein FLI-1 0.036
cts-1 Protein CTS-1 0.036
dhps-1 Protein DHPS-1 0.036
calu-1 Protein CALU-1 0.035
axl-1 Protein AXL-1 0.035
rps-6 Protein RPS-6 0.035
snr-2 Protein SNR-2 0.035
prp-21 Protein PRP-21 0.035
sdpn-1 Protein SDPN-1 0.035
hil-2 Protein HIL-2 0.035
imb-2 Protein IMB-2 0.034
CELE_C12D8.1 Protein C12D8.1 0.034
dars-1 Protein DARS-1 0.034
vps-45 Protein VPS-45 0.034
tbb-1 Protein TBB-1 0.034
mac-1 Protein MAC-1 0.034
klp-12 Protein KLP-12 0.034
mdt-8 Protein MDT-8 0.034
rpl-3 Protein RPL-3 0.033
F58B3.6 Protein F58B3.6 0.033
E01A2.6 Protein E01A2.6 0.033
nucb-1 Protein NUCB-1 0.033
rpt-4 Protein RPT-4 0.033
vha-8 Protein VHA-8 0.033
unc-112 Protein UNC-112 0.033
ttm-4 Protein TTM-4 0.033
mek-2 Protein MEK-2 0.033
vha-6 Protein VHA-6 0.033
sem-5 Protein SEM-5 0.033
F40G12.5 Protein F40G12.5 0.033
gst-7 Protein GST-7 0.033
bli-4 Protein BLI-4 0.033
Y65B4BR.5 Protein Y65B4BR.5 0.033
CELE_Y48B6A.6 Protein Y48B6A.6 0.033
ZK686.3 Protein ZK686.3 0.032
flh-1 Protein FLH-1 0.032
ant-1.4 Protein ANT-1.4 0.032
F47G9.1 Protein F47G9.1 0.032
unc-73 Protein UNC-73 0.032
CELE_F54D5.5 Protein F54D5.5 0.032
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Danio rerio
Name Description Probability Func Analog Organism
baxa bcl2-associated X protein, a 0.352
cmyb transcription factor cmyb 0.292
nrp1a neuropilin 1a 0.177
nf1a neurofibromin 1a 0.154
cxcr4b chemokine (C-X-C motif), receptor 4b 0.134
bcl2l1 bcl2-like 1 0.132
fgfr1a fibroblast growth factor receptor 1a 0.130
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.119
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.113
tp53 tumor protein p53 0.111
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.100
fzd7a frizzled homolog 7a 0.085
dusp6 dual specificity phosphatase 6 0.077
mapk14a mitogen-activated protein kinase 14a 0.076
vax2 ventral anterior homeobox 2 0.074
cdkn1c cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.069
fn1 fibronectin 1 0.060
ptgs2a prostaglandin-endoperoxide synthase 2a 0.059
ntn2 netrin 2 0.055
ube2g2 ubiquitin-conjugating enzyme E2G 2 0.052
nrg1 neuregulin 1 0.050
wnt11r wingless-type MMTV integration site family, member 11, related 0.050
lef1 lymphocyte enhancer binding factor 1 0.049
myod1 myogenic differentiation 1 0.048
erbb3a v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a 0.048
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.047
kdrl kinase insert domain receptor like 0.046
tbx1 T-box 1 0.046
stc1l stanniocalcin 1, like 0.043
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.042
evx1 even-skipped homeobox 1 0.039
ryk receptor-like tyrosine kinase 0.037
psen1 presenilin 1 0.036
ptgs1 prostaglandin-endoperoxide synthase 1 0.036
igf1 insulin-like growth factor 1 0.034
pitx3 paired-like homeodomain transcription factor 3 0.033
bida BH3 interacting domain death agonist 0.032
nrarpa notch-regulated ankyrin repeat protein a 0.031
rag1 recombination activating gene 1 0.031
sox7 SRY-box containing gene 7 0.031
cdkn1a cyclin-dependent kinase inhibitor 1A 0.031
plcg1 phospholipase C, gamma 1 0.030
runx1 runt-related transcription factor 1 0.029
dct dopachrome tautomerase 0.029
gadd45aa growth arrest and DNA-damage-inducible, alpha, a 0.028
mcl1a myeloid cell leukemia sequence 1a 0.028
mpx myeloid-specific peroxidase 0.026
cnn2 calponin 2 0.025
efna5a ephrin A5a 0.025
nrg2a neuregulin 2a 0.024
aox3 aldehyde oxidase 3 0.024
LOC567131 calcitonin gene-related peptide type 1 receptor-like 0.024
gnb2l1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.023
ntn1b netrin 1b 0.023
nucks1a nuclear casein kinase and cyclin-dependent kinase substrate 1a 0.023
mapk6 mitogen-activated protein kinase 6 0.023
park7 parkinson disease (autosomal recessive, early onset) 7 0.023
mmp2 matrix metalloproteinase 2 0.023
tgif1 TGFB-induced factor homeobox 1 0.022
rp2 retinitis pigmentosa 2 (X-linked recessive) 0.022
igf1ra insulin-like growth factor 1a receptor 0.022
sgk1 serum/glucocorticoid regulated kinase 1 0.022
nkx6.1 NK6 transcription factor related, locus 1 (Drosophila) 0.022
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.022
prkci protein kinase C, iota 0.021
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.021
sox2 SRY-box containing gene 2 0.020
sh3gl3 SH3-domain GRB2-like 3 0.020
wnt10a wingless-type MMTV integration site family, member 10a 0.020
nf1b neurofibromin 1b 0.020
cp ceruloplasmin 0.020
grem2 gremlin 2, cysteine knot superfamily 0.020
igfbp1b insulin-like growth factor binding protein 1b 0.020
sox4b SRY-box containing gene 4b 0.020
ube2d2 ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) 0.019
dkk1b dickkopf 1b 0.019
egr1 early growth response 1 0.019
gja3 gap junction protein, alpha 3 0.019
hmx1 H6 homeo box 1 0.018
znf703 zinc finger protein 703 0.018
nrp2a neuropilin 2a 0.018
naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.018
cxcl12b chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) 0.018
bactin1 bactin1 0.018
zgc:101724 zgc:101724 0.018
pak2b p21 (CDKN1A)-activated kinase 2b 0.018
lrrc33 leucine rich repeat containing 33 0.018
mcl1b myeloid cell leukemia sequence 1b 0.017
dlx6a distal-less homeobox gene 6a 0.017
sulf2l sulfatase 2, like 0.017
nkx2.5 NK2 transcription factor related 5 0.017
caprin1a cell cycle associated protein 1a 0.017
gnb1a guanine nucleotide binding protein (G protein), beta polypeptide 1a 0.017
grnb granulin b 0.017
fgf10a fibroblast growth factor 10a 0.017
foxo3b forkhead box O3b 0.017
mcm4 MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) 0.016
zdhhc8b zinc finger, DHHC-type containing 8b 0.016
acvr2a activin receptor IIa 0.016
mdm2 transformed 3T3 cell double minute 2 homolog (mouse) 0.016
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Ras85D Ras oncogene at 85D 1.000
tkv thickveins 0.923
rl rolled 0.711
kibra kibra ortholog 0.689
Lam Lamin 0.661
rpr reaper 0.586
dm diminutive 0.514
th thread 0.439
babo baboon 0.310
dco discs overgrown 0.283
Egfr Epidermal growth factor receptor 0.221
emc extra macrochaetae 0.197
sd scalloped 0.185
dpp decapentaplegic 0.162
jar jaguar 0.152
dsh dishevelled 0.138
Dcp-1 Death caspase-1 0.133
aop anterior open 0.128
NetB Netrin-B 0.123
Pp2B-14D Protein phosphatase 2B at 14D 0.123
p53 CG33336 gene product from transcript CG33336-RB 0.119
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.113
rst roughest 0.111
stumps CG31317 gene product from transcript CG31317-RC 0.104
so sine oculis 0.098
Hsp27 Heat shock protein 27 0.096
park parkin 0.094
gig gigas 0.089
Ef1gamma CG11901 gene product from transcript CG11901-RC 0.076
Nc Nedd2-like caspase 0.076
frc fringe connection 0.076
RagA CG11968 gene product from transcript CG11968-RA 0.066
Arr1 Arrestin 1 0.065
wg wingless 0.063
CG12214 CG12214 gene product from transcript CG12214-RB 0.061
Pcaf CG4107 gene product from transcript CG4107-RA 0.058
ci cubitus interruptus 0.053
imd immune deficiency 0.051
Dcr-2 Dicer-2 0.051
bsk basket 0.050
Src42A Src oncogene at 42A 0.050
rap retina aberrant in pattern 0.050
par-1 CG8201 gene product from transcript CG8201-RA 0.048
PHGPx CG12013 gene product from transcript CG12013-RC 0.048
Gap1 GTPase-activating protein 1 0.048
cora coracle 0.047
scny scrawny 0.046
Atg1 Autophagy-specific gene 1 0.046
Sin3A CG8815 gene product from transcript CG8815-RC 0.045
MED24 Mediator complex subunit 24 0.044
msn misshapen 0.044
jing CG9397 gene product from transcript CG9397-RI 0.043
TwdlE TweedleE 0.042
numb CG3779 gene product from transcript CG3779-RB 0.040
if inflated 0.039
CG6783 CG6783 gene product from transcript CG6783-RC 0.039
Atpalpha Na pump alpha subunit 0.039
myoglianin CG1838 gene product from transcript CG1838-RD 0.039
Hsc70-4 Heat shock protein cognate 4 0.039
Moe Moesin 0.039
EcR Ecdysone receptor 0.038
noc no ocelli 0.038
Rbf Retinoblastoma-family protein 0.038
ap apterous 0.037
TBPH CG10327 gene product from transcript CG10327-RC 0.036
ex expanded 0.036
Cbl CG7037 gene product from transcript CG7037-RB 0.035
Socs36E Suppressor of cytokine signaling at 36E 0.035
W Wrinkled 0.034
nej nejire 0.034
Mkp3 Mitogen-activated protein kinase phosphatase 3 0.033
Pk61C Protein kinase 61C 0.033
Akt1 CG4006 gene product from transcript CG4006-RA 0.033
psidin phagocyte signaling impaired 0.032
hpo hippo 0.032
spi spitz 0.032
sr stripe 0.032
row relative of woc 0.031
Rac2 CG8556 gene product from transcript CG8556-RA 0.030
gbb glass bottom boat 0.030
CG8801 CG8801 gene product from transcript CG8801-RA 0.030
S6kII RPS6-protein kinase-II 0.028
Jafrac1 thioredoxin peroxidase 1 0.028
put punt 0.027
Hs6st Heparan sulfate 6-O-sulfotransferase 0.027
Rac1 CG2248 gene product from transcript CG2248-RA 0.027
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.027
Tl Toll 0.027
caz cabeza 0.026
bchs blue cheese 0.026
pnt pointed 0.026
btl breathless 0.025
CG8443 CG8443 gene product from transcript CG8443-RA 0.025
tefu telomere fusion 0.025
CG5794 CG5794 gene product from transcript CG5794-RB 0.025
HtrA2 CG8464 gene product from transcript CG8464-RA 0.024
Mad Mothers against dpp 0.023
Sir2 CG5216 gene product from transcript CG5216-RA 0.023
Adar Adenosine deaminase acting on RNA 0.023
Sra-1 specifically Rac1-associated protein 1 0.023
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Homo sapiens
Name Description Probability Func Analog Organism
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.000
UBC ubiquitin C 1.000
BCL2 B-cell CLL/lymphoma 2 1.000
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.000
PML promyelocytic leukemia 1.000
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 1.000
MDM2 Mdm2 p53 binding protein homolog (mouse) 1.000
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.000
TP53 tumor protein p53 0.999
BCL2L1 BCL2-like 1 0.999
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.999
MAPK8 mitogen-activated protein kinase 8 0.998
SQSTM1 sequestosome 1 0.997
XIAP X-linked inhibitor of apoptosis 0.997
BIRC3 baculoviral IAP repeat containing 3 0.996
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.996
TRAF2 TNF receptor-associated factor 2 0.996
DAXX death-domain associated protein 0.991
EGFR epidermal growth factor receptor 0.991
BAX BCL2-associated X protein 0.990
CFLAR CASP8 and FADD-like apoptosis regulator 0.987
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.987
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.984
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.978
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.968
TRAF6 TNF receptor-associated factor 6 0.964
FAS Fas (TNF receptor superfamily, member 6) 0.963
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.944
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.940
FN1 fibronectin 1 0.938
IL8 interleukin 8 0.937
PSEN1 presenilin 1 0.935
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.931
FADD Fas (TNFRSF6)-associated via death domain 0.930
TRADD TNFRSF1A-associated via death domain 0.926
RNF11 ring finger protein 11 0.913
TP53BP2 tumor protein p53 binding protein, 2 0.913
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.909
BAD BCL2-associated agonist of cell death 0.909
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.907
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.896
APP amyloid beta (A4) precursor protein 0.893
BIRC2 baculoviral IAP repeat containing 2 0.888
FHL2 four and a half LIM domains 2 0.885
TRAF3 TNF receptor-associated factor 3 0.874
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.872
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.870
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.867
TRAF1 TNF receptor-associated factor 1 0.865
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.838
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.836
CAV1 caveolin 1, caveolae protein, 22kDa 0.824
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.824
FGB fibrinogen beta chain 0.823
HDAC1 histone deacetylase 1 0.820
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.816
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.815
FLNA filamin A, alpha 0.811
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.801
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.795
ANXA1 annexin A1 0.783
JUN jun proto-oncogene 0.777
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.769
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.768
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.756
LGALS1 lectin, galactoside-binding, soluble, 1 0.755
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.737
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.728
TEK TEK tyrosine kinase, endothelial 0.728
S100A8 S100 calcium binding protein A8 0.727
GSK3B glycogen synthase kinase 3 beta 0.719
VEGFA vascular endothelial growth factor A 0.717
HDAC6 histone deacetylase 6 0.717
ANXA2 annexin A2 0.716
SOCS3 suppressor of cytokine signaling 3 0.713
MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) 0.711
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.707
PTEN phosphatase and tensin homolog 0.706
VIM vimentin 0.699
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.695
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.667
S100A9 S100 calcium binding protein A9 0.666
BID BH3 interacting domain death agonist 0.654
IFITM3 interferon induced transmembrane protein 3 (1-8U) 0.651
S100B S100 calcium binding protein B 0.651
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.645
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.632
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.629
PLAUR plasminogen activator, urokinase receptor 0.619
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.615
S100A4 S100 calcium binding protein A4 0.613
AR androgen receptor 0.609
BTRC beta-transducin repeat containing 0.599
PRKCA protein kinase C, alpha 0.598
MAPK1 mitogen-activated protein kinase 1 0.597
TGIF1 TGFB-induced factor homeobox 1 0.596
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.587
SYK spleen tyrosine kinase 0.583
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.576
S100A6 S100 calcium binding protein A6 0.571
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Mus musculus
Name Description Probability Func Analog Organism
Pten phosphatase and tensin homolog 0.997
Vegfa vascular endothelial growth factor A 0.996
Trp53 transformation related protein 53 0.995
Bcl2 B-cell leukemia/lymphoma 2 0.992
Runx1 runt related transcription factor 1 0.992
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.990
Cd44 CD44 antigen 0.982
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.978
Tnf tumor necrosis factor 0.976
Ptgs2 prostaglandin-endoperoxide synthase 2 0.972
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.967
Pax2 paired box gene 2 0.966
Gli3 GLI-Kruppel family member GLI3 0.958
Igh immunoglobulin heavy chain complex 0.956
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.953
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.953
Rarg retinoic acid receptor, gamma 0.952
Skil SKI-like 0.951
Thbs1 thrombospondin 1 0.945
Nos1 nitric oxide synthase 1, neuronal 0.935
Mmp9 matrix metallopeptidase 9 0.933
Psen1 presenilin 1 0.931
Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform 0.926
Fgfr1 fibroblast growth factor receptor 1 0.921
Tgfbr2 transforming growth factor, beta receptor II 0.919
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.918
Casp8 caspase 8 0.897
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.895
Ikzf1 IKAROS family zinc finger 1 0.893
Col1a1 collagen, type I, alpha 1 0.890
Ctnnb1 catenin (cadherin associated protein), beta 1 0.889
Mdm2 transformed mouse 3T3 cell double minute 2 0.880
Rxra retinoid X receptor alpha 0.874
Hdac2 histone deacetylase 2 0.870
Hoxa11 homeobox A11 0.865
Shh sonic hedgehog 0.865
Fgfr2 fibroblast growth factor receptor 2 0.861
Sfrp2 secreted frizzled-related protein 2 0.852
Rbl1 retinoblastoma-like 1 (p107) 0.851
Ncoa3 nuclear receptor coactivator 3 0.851
Prrx2 paired related homeobox 2 0.848
Nos3 nitric oxide synthase 3, endothelial cell 0.843
Lhx1 LIM homeobox protein 1 0.843
Lyz2 lysozyme 2 0.838
Wt1 Wilms tumor 1 homolog 0.835
Apc adenomatosis polyposis coli 0.835
Tgfb1 transforming growth factor, beta 1 0.834
Acvr1 activin A receptor, type 1 0.824
Gdnf glial cell line derived neurotrophic factor 0.824
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.815
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.810
Mapk8 mitogen-activated protein kinase 8 0.798
Rybp RING1 and YY1 binding protein 0.787
Pax3 paired box gene 3 0.770
Rara retinoic acid receptor, alpha 0.768
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.765
Bcl3 B-cell leukemia/lymphoma 3 0.763
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.757
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.741
Tgfbr1 transforming growth factor, beta receptor I 0.735
Fst follistatin 0.734
Stk4 serine/threonine kinase 4 0.731
Foxp3 forkhead box P3 0.725
Traf6 TNF receptor-associated factor 6 0.721
Nog noggin 0.719
Hoxa13 homeobox A13 0.716
Wnt5a wingless-related MMTV integration site 5A 0.711
Ren1 renin 1 structural 0.702
Meox2 mesenchyme homeobox 2 0.701
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.700
Mcl1 myeloid cell leukemia sequence 1 0.695
S100a9 S100 calcium binding protein A9 (calgranulin B) 0.693
Nos2 nitric oxide synthase 2, inducible 0.690
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.684
Myc myelocytomatosis oncogene 0.683
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.680
Ikbkb inhibitor of kappaB kinase beta 0.679
Pax8 paired box gene 8 0.678
Insr insulin receptor 0.670
Agtr1a angiotensin II receptor, type 1a 0.669
Tlr4 toll-like receptor 4 0.669
Fbn1 fibrillin 1 0.664
Ret ret proto-oncogene 0.661
Ptk2 PTK2 protein tyrosine kinase 2 0.655
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.652
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.645
Ccr1 chemokine (C-C motif) receptor 1 0.644
Cdkn2d cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.636
Hoxd13 homeobox D13 0.634
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.629
Ptch1 patched homolog 1 0.627
Csf1 colony stimulating factor 1 (macrophage) 0.624
Casp1 caspase 1 0.606
Mapk14 mitogen-activated protein kinase 14 0.605
Kitl kit ligand 0.604
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.601
Cd40 CD40 antigen 0.600
Ednra endothelin receptor type A 0.599
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.598
Lmna lamin A 0.583
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Rattus norvegicus
Name Description Probability Func Analog Organism
S100a9 S100 calcium binding protein A9 0.438
S100a8 S100 calcium binding protein A8 0.180
Arpc1b actin related protein 2/3 complex, subunit 1B 0.169
Hck hemopoietic cell kinase 0.141
Icam1 intercellular adhesion molecule 1 0.102
Cp ceruloplasmin 0.100
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.099
Sirpa signal-regulatory protein alpha 0.091
Casp3 caspase 3 0.090
Smad1 SMAD family member 1 0.087
Vat1 vesicle amine transport protein 1 homolog (T californica) 0.085
RT1-Ba RT1 class II, locus Ba 0.085
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.081
Epn1 Epsin 1 0.080
Rara retinoic acid receptor, alpha 0.077
Adrbk1 adrenergic, beta, receptor kinase 1 0.076
Il1b interleukin 1 beta 0.076
Arrdc1 arrestin domain containing 1 0.071
Cd14 CD14 molecule 0.071
Jag2 jagged 2 0.068
Vcp valosin-containing protein 0.065
Dctn4 dynactin 4 0.065
Tgfb1 transforming growth factor, beta 1 0.064
RGD1562618 similar to RIKEN cDNA 6030419C18 gene 0.060
Tmod3 tropomodulin 3 0.060
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.059
Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.056
Ptprc protein tyrosine phosphatase, receptor type, C 0.056
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.055
Anxa2 annexin A2 0.051
Jak1 Janus kinase 1 0.050
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.049
Cdk4 cyclin-dependent kinase 4 0.046
RT1-Bb RT1 class II, locus Bb 0.046
Fgfr2 fibroblast growth factor receptor 2 0.046
Oaz1 ornithine decarboxylase antizyme 1 0.044
Ralgds ral guanine nucleotide dissociation stimulator 0.043
Exoc5 exocyst complex component 5 0.043
Impdh2 IMP (inosine monophosphate) dehydrogenase 2 0.041
Zyx zyxin 0.038
Map3k1 mitogen activated protein kinase kinase kinase 1 0.037
Mprip myosin phosphatase Rho interacting protein 0.037
Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.036
Cd86 CD86 molecule 0.036
Socs3 suppressor of cytokine signaling 3 0.036
Orai1 ORAI calcium release-activated calcium modulator 1 0.035
RT1-Da RT1 class II, locus Da 0.035
Sdc3 syndecan 3 0.035
Ccnd3 cyclin D3 0.034
Aprt adenine phosphoribosyl transferase 0.033
Cxcl10 chemokine (C-X-C motif) ligand 10 0.033
Jak2 Janus kinase 2 0.033
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.033
Usp3 ubiquitin specific peptidase 3 0.032
Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 0.032
Ddr1 discoidin domain receptor tyrosine kinase 1 0.031
Flt1 FMS-related tyrosine kinase 1 0.031
Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.030
Map2k2 mitogen activated protein kinase kinase 2 0.029
Birc2 baculoviral IAP repeat-containing 2 0.029
Mcm6 minichromosome maintenance complex component 6 0.029
St13 suppression of tumorigenicity 13 0.029
Ube2i ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.028
Prdm2 PR domain containing 2, with ZNF domain 0.028
Slc25a4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.028
Creb1 cAMP responsive element binding protein 1 0.027
Pawr PRKC, apoptosis, WT1, regulator 0.027
Mobkl2a MOB1, Mps One Binder kinase activator-like 2A (yeast) 0.027
Reg3a regenerating islet-derived 3 alpha 0.027
Cd53 Cd53 molecule 0.027
Stat3 signal transducer and activator of transcription 3 0.026
Ptafr platelet-activating factor receptor 0.026
Acpp acid phosphatase, prostate 0.026
Ptpn7 protein tyrosine phosphatase, non-receptor type 7 0.025
Hnrnpf heterogeneous nuclear ribonucleoprotein F 0.025
Cyc1 cytochrome c-1 0.025
Anxa4 annexin A4 0.024
Anxa1 annexin A1 0.024
Nras neuroblastoma ras oncogene 0.024
Cast calpastatin 0.023
Smad7 SMAD family member 7 0.023
Pdp1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.023
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.023
Cd9 CD9 molecule 0.023
Cr1l complement component (3b/4b) receptor 1-like 0.022
Mtch1 mitochondrial carrier homolog 1 (C. elegans) 0.022
Timp2 TIMP metallopeptidase inhibitor 2 0.022
Marcks myristoylated alanine rich protein kinase C substrate 0.022
Myh9 myosin, heavy chain 9, non-muscle 0.022
Trim23 tripartite motif-containing 23 0.022
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.022
Batf basic leucine zipper transcription factor, ATF-like 0.021
Fkbp1a FK506 binding protein 1a 0.021
Pdia4 protein disulfide isomerase family A, member 4 0.021
Cdc42bpb CDC42 binding protein kinase beta (DMPK-like) 0.020
Il1a interleukin 1 alpha 0.020
Pim1 pim-1 oncogene 0.020
Fut4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.020
Cdc34 cell division cycle 34 homolog (S. cerevisiae) 0.020
Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) 0.020
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism