The network for 'positive regulation of glial cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of glial cell differentiation

Any process that activates or increases the frequency, rate or extent of glia cell differentiation.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
bmp2b bone morphogenetic protein 2b 0.696
ascl1a achaete-scute complex-like 1a (Drosophila) 0.615
fgf8a fibroblast growth factor 8 a 0.545
nkx6.1 NK6 transcription factor related, locus 1 (Drosophila) 0.424
pax6a paired box gene 6a 0.404
gdf6a growth differentiation factor 6a 0.377
tbx1 T-box 1 0.368
cdh2 cadherin 2, neuronal 0.363
shha sonic hedgehog a 0.358
ins preproinsulin 0.352
dla deltaA 0.285
nkx2.2a NK2 transcription factor related 2a 0.268
mnx1 motor neuron and pancreas homeobox 1 0.265
ptch2 patched 2 0.239
bmp4 bone morphogenetic protein 4 0.199
chd chordin 0.188
neurog1 neurogenin 1 0.147
neurod neurogenic differentiation 0.128
met met proto-oncogene (hepatocyte growth factor receptor) 0.126
fzd8a frizzled homolog 8a 0.111
cxcr4b chemokine (C-X-C motif), receptor 4b 0.111
dlc deltaC 0.107
lhx1a LIM homeobox 1a 0.107
prox1 prospero-related homeobox gene 1 0.104
pax2a paired box gene 2a 0.095
fabp11a fatty acid binding protein 11a 0.093
tbx2b T-box 2b 0.075
cyp26a1 cytochrome P450, subfamily XXVIA, polypeptide 1 0.074
robo3 roundabout homolog 3 0.074
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.074
isl1 islet1 0.073
hnf1ba HNF1 homeobox Ba 0.073
sfrp5 secreted frizzled-related protein 5 0.071
dld deltaD 0.070
fgf3 fibroblast growth factor 3 0.067
rarab retinoic acid receptor, alpha b 0.064
cx43 connexin 43 0.064
tbx5a T-box 5a 0.062
cdh1 cadherin 1, epithelial 0.061
tal1 T-cell acute lymphocytic leukemia 1 0.061
pax6b paired box gene 6b 0.059
foxa2 forkhead box A2 0.059
ascl1b achaete-scute complex-like 1b (Drosophila) 0.057
gsc goosecoid 0.056
mib mind bomb 0.056
smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.051
dlb deltaB 0.051
cdx4 caudal type homeo box transcription factor 4 0.050
zgc:171553 zgc:171553 0.049
tbx20 T-box 20 0.049
gli2a GLI-Kruppel family member GLI2a 0.048
pea3 ETS-domain transcription factor pea3 0.048
myca myelocytomatosis oncogene a 0.048
her6 hairy-related 6 0.048
osr1 odd-skipped related 1 (Drosophila) 0.046
ntla no tail a 0.046
mych myelocytomatosis oncogene homolog 0.046
ddx39aa DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa 0.046
col2a1a collagen type II, alpha-1a 0.045
crb2a crumbs homolog 2a 0.044
crabp2a cellular retinoic acid binding protein 2, a 0.043
rad21 RAD21 homolog (S. pombe) 0.043
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.043
rtf1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.042
vsx2 visual system homeobox 2 0.041
sox9b SRY-box containing gene 9b 0.040
tgfb3 transforming growth factor, beta 3 0.038
cdh5 cadherin 5 0.038
zgc:64114 zgc:64114 0.038
lef1 lymphocyte enhancer binding factor 1 0.037
sox3 SRY-box containing gene 3 0.036
cxcr4a chemokine (C-X-C motif) receptor 4a 0.036
msxc muscle segment homeobox C 0.035
ilf2 interleukin enhancer binding factor 2 0.034
gata6 GATA-binding protein 6 0.034
th tyrosine hydroxylase 0.033
mpped2 metallophosphoesterase domain containing 2 0.033
myod1 myogenic differentiation 1 0.032
prkci protein kinase C, iota 0.032
pacsin3 protein kinase C and casein kinase substrate in neurons 3 0.032
krml2.2 Kreisler (mouse) maf-related leucine zipper homolog 2.2 0.032
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.031
apc adenomatosis polyposis coli 0.031
gata3 GATA-binding protein 3 0.031
hoxb5a homeo box B5a 0.031
jag2 jagged 2 0.030
gli1 GLI-Kruppel family member 1 0.030
efna5b ephrin A5b 0.030
unc5b unc-5 homolog B (C. elegans) 0.029
dlx3b distal-less homeobox gene 3b 0.029
sox2 SRY-box containing gene 2 0.029
dlx5a distal-less homeobox gene 5a 0.028
kita kit receptor a 0.028
s1pr2 sphingosine-1-phosphate receptor 2 0.028
meis2.2 myeloid ecotropic viral integration site 2.2 0.028
nkx6.2 NK6 transcription factor related, locus 2 0.027
tp53 tumor protein p53 0.027
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.027
tmprss4a transmembrane protease, serine 4a 0.026
dbx1a developing brain homeobox 1a 0.026
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
HDAC1 histone deacetylase 1 0.989
HDAC2 histone deacetylase 2 0.857
PLAU plasminogen activator, urokinase 0.224
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.102
DNM1 dynamin 1 0.089
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.071
BMPR1A bone morphogenetic protein receptor, type IA 0.067
JAG1 jagged 1 0.059
RIN3 Ras and Rab interactor 3 0.055
IL1R1 interleukin 1 receptor, type I 0.050
TP53 tumor protein p53 0.046
SYNJ1 synaptojanin 1 0.032
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.027
NOTCH3 notch 3 0.027
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.025
SNX9 sorting nexin 9 0.023
IL1RAP interleukin 1 receptor accessory protein 0.022
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.022
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.022
YAP1 Yes-associated protein 1 0.019
IL1RN interleukin 1 receptor antagonist 0.019
RBBP4 retinoblastoma binding protein 4 0.019
WWOX WW domain containing oxidoreductase 0.018
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.018
SF3A1 splicing factor 3a, subunit 1, 120kDa 0.017
JAK1 Janus kinase 1 0.016
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.016
DNM2 dynamin 2 0.016
PLAT plasminogen activator, tissue 0.016
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.016
LIFR leukemia inhibitory factor receptor alpha 0.015
RCOR1 REST corepressor 1 0.015
IL6R interleukin 6 receptor 0.015
YY1 YY1 transcription factor 0.014
CDC5L CDC5 cell division cycle 5-like (S. pombe) 0.014
XIAP X-linked inhibitor of apoptosis 0.013
KAT2B K(lysine) acetyltransferase 2B 0.013
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.013
FSTL1 follistatin-like 1 0.013
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.012
CCR5 chemokine (C-C motif) receptor 5 0.012
EP300 E1A binding protein p300 0.012
REPS2 RALBP1 associated Eps domain containing 2 0.012
CUX1 cut-like homeobox 1 0.011
AHR aryl hydrocarbon receptor 0.011
CHD4 chromodomain helicase DNA binding protein 4 0.011
IL6 interleukin 6 (interferon, beta 2) 0.011
TOP1 topoisomerase (DNA) I 0.011
ESRRG estrogen-related receptor gamma 0.011
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.011
CCL20 chemokine (C-C motif) ligand 20 0.011
OSMR oncostatin M receptor 0.010
SMAD7 SMAD family member 7 0.010
PTK2 PTK2 protein tyrosine kinase 2 0.010
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.010
IL8 interleukin 8 0.010
TARBP2 TAR (HIV-1) RNA binding protein 2 0.010
GAB1 GRB2-associated binding protein 1 0.010
NOG noggin 0.010
CCL2 chemokine (C-C motif) ligand 2 0.010
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.010
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Foxc1 forkhead box C1 1.000
Gli3 GLI-Kruppel family member GLI3 0.999
Otx2 orthodenticle homolog 2 (Drosophila) 0.999
Pax3 paired box gene 3 0.997
Sox9 SRY-box containing gene 9 0.997
Fgfr2 fibroblast growth factor receptor 2 0.993
Eya1 eyes absent 1 homolog (Drosophila) 0.988
Emx1 empty spiracles homolog 1 (Drosophila) 0.988
Ctnnb1 catenin (cadherin associated protein), beta 1 0.988
Tgfb2 transforming growth factor, beta 2 0.983
Hand2 heart and neural crest derivatives expressed transcript 2 0.983
Sox2 SRY-box containing gene 2 0.979
Msx1 homeobox, msh-like 1 0.977
Foxc2 forkhead box C2 0.973
Fgf8 fibroblast growth factor 8 0.973
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.972
Tcfap2a transcription factor AP-2, alpha 0.967
Fgfr1 fibroblast growth factor receptor 1 0.965
Chrd chordin 0.962
Hand1 heart and neural crest derivatives expressed transcript 1 0.962
Tbx1 T-box 1 0.957
Isl1 ISL1 transcription factor, LIM/homeodomain 0.941
Gli2 GLI-Kruppel family member GLI2 0.933
Pten phosphatase and tensin homolog 0.932
Smo smoothened homolog (Drosophila) 0.924
Foxg1 forkhead box G1 0.918
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.911
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.904
Pax6 paired box gene 6 0.902
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.861
Pax2 paired box gene 2 0.860
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.851
Hoxd3 homeobox D3 0.841
Id3 inhibitor of DNA binding 3 0.810
Hes1 hairy and enhancer of split 1 (Drosophila) 0.805
Bmp4 bone morphogenetic protein 4 0.799
Dlx5 distal-less homeobox 5 0.796
Jag1 jagged 1 0.765
Gsc goosecoid homeobox 0.757
Rarb retinoic acid receptor, beta 0.745
Rarg retinoic acid receptor, gamma 0.737
Nkx3-2 NK3 homeobox 2 0.716
Pax8 paired box gene 8 0.712
Nog noggin 0.705
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.636
Hoxa1 homeobox A1 0.624
Hes5 hairy and enhancer of split 5 (Drosophila) 0.608
Prrx1 paired related homeobox 1 0.600
Chd7 chromodomain helicase DNA binding protein 7 0.580
Bmp7 bone morphogenetic protein 7 0.548
Insm1 insulinoma-associated 1 0.516
Id1 inhibitor of DNA binding 1 0.508
Pitx2 paired-like homeodomain transcription factor 2 0.505
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.499
Sox11 SRY-box containing gene 11 0.497
Tgfbr2 transforming growth factor, beta receptor II 0.489
Hoxa2 homeobox A2 0.477
Emx2 empty spiracles homolog 2 (Drosophila) 0.476
Notch1 Notch gene homolog 1 (Drosophila) 0.449
Rxra retinoid X receptor alpha 0.440
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.436
Fgf10 fibroblast growth factor 10 0.434
Gbx2 gastrulation brain homeobox 2 0.421
Vangl2 vang-like 2 (van gogh, Drosophila) 0.416
Runx2 runt related transcription factor 2 0.403
Rb1 retinoblastoma 1 0.403
Psen1 presenilin 1 0.395
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.379
Zeb1 zinc finger E-box binding homeobox 1 0.370
Ntf3 neurotrophin 3 0.368
Sox4 SRY-box containing gene 4 0.365
Lhx3 LIM homeobox protein 3 0.360
Ccr2 chemokine (C-C motif) receptor 2 0.356
Adam17 a disintegrin and metallopeptidase domain 17 0.346
Cd44 CD44 antigen 0.345
Sall3 sal-like 3 (Drosophila) 0.344
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.336
Gja1 gap junction protein, alpha 1 0.325
Fgfr3 fibroblast growth factor receptor 3 0.311
Meox2 mesenchyme homeobox 2 0.308
Nodal nodal 0.295
Gsx1 GS homeobox 1 0.292
Tcf21 transcription factor 21 0.292
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.290
Ptf1a pancreas specific transcription factor, 1a 0.283
Ccl2 chemokine (C-C motif) ligand 2 0.278
Trp53 transformation related protein 53 0.273
Nfatc2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.268
Efnb2 ephrin B2 0.255
Foxp3 forkhead box P3 0.254
Pax9 paired box gene 9 0.252
Hoxd1 homeobox D1 0.250
Ikzf1 IKAROS family zinc finger 1 0.249
Hoxa3 homeobox A3 0.227
Phox2b paired-like homeobox 2b 0.220
Neurog2 neurogenin 2 0.219
Pdx1 pancreatic and duodenal homeobox 1 0.219
Ifng interferon gamma 0.214
Bmp2 bone morphogenetic protein 2 0.209
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism