The network for 'antimicrobial peptide biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

antimicrobial peptide biosynthetic process

The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Rel Relish 0.948
AttA Attacin-A 0.889
PGRP-LC Peptidoglycan recognition protein LC 0.863
DptB Diptericin B 0.641
Irc Immune-regulated catalase 0.607
ird5 immune response deficient 5 0.594
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.554
PGRP-SA Peptidoglycan recognition protein SA 0.547
grass Gram-positive Specific Serine protease 0.363
Mtk Metchnikowin 0.313
Spn28D Serpin 28D 0.304
SPE Spatzle-Processing Enzyme 0.285
imd immune deficiency 0.250
Dredd Death related ced-3/Nedd2-like protein 0.239
Spn27A Serpin 27A 0.239
AttC Attacin-C 0.185
Spn1 Serine protease inhibitor 1 0.175
Myd88 CG2078 gene product from transcript CG2078-RA 0.156
BG4 CG12297 gene product from transcript CG12297-RA 0.153
Glt Glutactin 0.144
fon fondue 0.140
ird1 immune response deficient 1 0.135
CG32185 CG32185 gene product from transcript CG32185-RA 0.133
spz spatzle 0.131
Tl Toll 0.125
CG9184 CG9184 gene product from transcript CG9184-RB 0.114
Sp7 Serine protease 7 0.108
Drs Drosomycin 0.099
psh persephone 0.093
pirk poor Imd response upon knock-in 0.091
sc scute 0.090
hth homothorax 0.090
CG15917 CG15917 gene product from transcript CG15917-RA 0.089
GNBP3 Gram-negative bacteria binding protein 3 0.084
AGO2 Argonaute 2 0.075
eater CG6124 gene product from transcript CG6124-RB 0.074
Dpt Diptericin 0.071
CG12766 CG12766 gene product from transcript CG12766-RA 0.067
key kenny 0.065
IM18 Immune induced molecule 18 0.064
CG18594 CG18594 gene product from transcript CG18594-RA 0.060
Traf4 TNF-receptor-associated factor 4 0.059
Mpk2 CG5475 gene product from transcript CG5475-RB 0.057
CG7910 CG7910 gene product from transcript CG7910-RA 0.056
PGRP-LF Peptidoglycan recognition protein LF 0.054
TM9SF4 CG7364 gene product from transcript CG7364-RA 0.053
modSP modular serine protease 0.052
PGRP-LB Peptidoglycan recognition protein LB 0.051
Ark Apaf-1-related-killer 0.050
scny scrawny 0.048
spirit Serine Protease Immune Response Integrator 0.048
PGRP-SB1 CG9681 gene product from transcript CG9681-RA 0.047
GNBP1 Gram-negative bacteria binding protein 1 0.045
Duox Dual oxidase 0.045
CecC Cecropin C 0.044
amos absent MD neurons and olfactory sensilla 0.042
nub nubbin 0.042
HLHmbeta E(spl) region transcript mbeta 0.040
bin3 bicoid-interacting protein 3 0.039
fz2 frizzled 2 0.036
l(3)mbn lethal (3) malignant blood neoplasm 0.035
Spn77Ba Serpin 77Ba 0.034
CecA2 Cecropin A2 0.034
He Hemese 0.034
E(spl) Enhancer of split 0.031
CG8586 CG8586 gene product from transcript CG8586-RA 0.031
CG31326 CG31326 gene product from transcript CG31326-RA 0.031
pxb CG33207 gene product from transcript CG33207-RB 0.030
nimC1 nimrod C1 0.030
slp1 sloppy paired 1 0.029
PGRP-LE Peptidoglycan recognition protein LE 0.029
eg eagle 0.028
bowl brother of odd with entrails limited 0.028
Toll-7 CG8595 gene product from transcript CG8595-RA 0.028
bcd bicoid 0.027
osk oskar 0.027
B-H2 BarH2 0.027
upd2 unpaired 2 0.026
rpr reaper 0.026
nmo nemo 0.024
Med Medea 0.024
hb hunchback 0.024
HLHmgamma E(spl) region transcript mgamma 0.023
sv shaven 0.023
spheroide CG9675 gene product from transcript CG9675-RA 0.023
CG15065 CG15065 gene product from transcript CG15065-RA 0.022
Atg13 Autophagy-specific gene 13 0.022
pzg putzig 0.022
tna tonalli 0.022
TepIII Thiolester containing protein III 0.022
zen zerknullt 0.022
pum pumilio 0.022
CecA1 Cecropin A1 0.022
tld tolloid 0.021
odd odd skipped 0.021
CG13641 CG13641 gene product from transcript CG13641-RA 0.021
CG16713 CG16713 gene product from transcript CG16713-RA 0.021
nec necrotic 0.021
alphaTub67C alpha-Tubulin at 67C 0.021
tsl torso-like 0.020
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 1.000
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.998
Tnf tumor necrosis factor 0.997
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.989
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.987
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.984
Ikbkb inhibitor of kappaB kinase beta 0.984
Ikbkg inhibitor of kappaB kinase gamma 0.975
Trp53 transformation related protein 53 0.768
Lyz2 lysozyme 2 0.663
Pycard PYD and CARD domain containing 0.650
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.643
Casp1 caspase 1 0.636
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.630
Igh immunoglobulin heavy chain complex 0.581
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.558
Icam1 intercellular adhesion molecule 1 0.554
Ccl2 chemokine (C-C motif) ligand 2 0.507
Tlr4 toll-like receptor 4 0.476
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.410
Il1b interleukin 1 beta 0.392
Fas Fas (TNF receptor superfamily member 6) 0.350
Cd44 CD44 antigen 0.309
Cd40 CD40 antigen 0.292
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.290
Ccr1 chemokine (C-C motif) receptor 1 0.287
Rxra retinoid X receptor alpha 0.283
Sfpi1 SFFV proviral integration 1 0.283
Il4ra interleukin 4 receptor, alpha 0.270
Myd88 myeloid differentiation primary response gene 88 0.265
Irf1 interferon regulatory factor 1 0.249
Cyld cylindromatosis (turban tumor syndrome) 0.240
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.235
Nlrp3 NLR family, pyrin domain containing 3 0.219
Socs1 suppressor of cytokine signaling 1 0.211
Gbp5 guanylate binding protein 5 0.204
Clec4d C-type lectin domain family 4, member d 0.198
Cdx2 caudal type homeobox 2 0.195
Neurog2 neurogenin 2 0.192
Ccl4 chemokine (C-C motif) ligand 4 0.188
Ltbp2 latent transforming growth factor beta binding protein 2 0.185
Ccl7 chemokine (C-C motif) ligand 7 0.183
Bcl3 B-cell leukemia/lymphoma 3 0.180
Il18 interleukin 18 0.171
C1qtnf1 C1q and tumor necrosis factor related protein 1 0.163
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.157
Tax1bp1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.151
Tcra T-cell receptor alpha chain 0.143
Ikzf1 IKAROS family zinc finger 1 0.140
Card11 caspase recruitment domain family, member 11 0.137
Inhba inhibin beta-A 0.135
Tnip1 TNFAIP3 interacting protein 1 0.134
Tcf3 transcription factor 3 0.131
Gbp2 guanylate binding protein 2 0.130
C3ar1 complement component 3a receptor 1 0.128
Trp73 transformation related protein 73 0.123
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.120
Cxcl13 chemokine (C-X-C motif) ligand 13 0.115
Plau plasminogen activator, urokinase 0.114
Aim2 absent in melanoma 2 0.114
Gata1 GATA binding protein 1 0.113
Cxcl2 chemokine (C-X-C motif) ligand 2 0.113
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.113
Cdx1 caudal type homeobox 1 0.111
2010106G01Rik RIKEN cDNA 2010106G01 gene 0.111
Itgb2 integrin beta 2 0.110
Clec4e C-type lectin domain family 4, member e 0.101
Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) 0.099
Il6 interleukin 6 0.099
Csf1 colony stimulating factor 1 (macrophage) 0.096
S1pr2 sphingosine-1-phosphate receptor 2 0.091
Ifng interferon gamma 0.090
E2f1 E2F transcription factor 1 0.089
Sykb spleen tyrosine kinase 0.088
Nodal nodal 0.084
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.084
Fgf4 fibroblast growth factor 4 0.084
Il1rn interleukin 1 receptor antagonist 0.084
Ppard peroxisome proliferator activator receptor delta 0.083
C5ar1 complement component 5a receptor 1 0.082
Sox3 SRY-box containing gene 3 0.081
Wnt6 wingless-related MMTV integration site 6 0.081
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.078
Gbp3 guanylate binding protein 3 0.078
Msr1 macrophage scavenger receptor 1 0.076
Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 0.074
Ephb2 Eph receptor B2 0.074
Dlx1 distal-less homeobox 1 0.073
Chuk conserved helix-loop-helix ubiquitous kinase 0.072
Runx1 runt related transcription factor 1 0.072
Hmx3 H6 homeobox 3 0.071
Fcgr4 Fc receptor, IgG, low affinity IV 0.071
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.070
Pou3f1 POU domain, class 3, transcription factor 1 0.069
Mta1 metastasis associated 1 0.069
Il7 interleukin 7 0.068
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.068
Il2rg interleukin 2 receptor, gamma chain 0.067
Irg1 immunoresponsive gene 1 0.066
Gm12185 predicted gene 12185 0.065
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Rattus norvegicus
Name Description Probability Func Analog Organism