IMP
Process View
The network for 'peptidyl diphthamide biosynthetic process from peptidyl histidine' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
peptidyl diphthamide biosynthetic process from peptidyl histidine
The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| DPH2 | Dph2p | 0.608 | |
| DPH1 | Dph1p | 0.287 | |
| KTI11 | Kti11p | 0.060 | |
| SIL1 | Sil1p | 0.051 | |
| MNN1 | Mnn1p | 0.035 | |
| RCL1 | Rcl1p | 0.034 | |
| YLR264C-A | hypothetical protein | 0.029 | |
| SMM1 | Smm1p | 0.028 | |
| SRD1 | Srd1p | 0.027 | |
| MER1 | Mer1p | 0.027 | |
| ARG8 | Arg8p | 0.024 | |
| CUP1-1 | Cup1-1p | 0.024 | |
| YAR068W | hypothetical protein | 0.022 | |
| LEU2 | Leu2p | 0.022 | |
| YLR042C | hypothetical protein | 0.022 | |
| YLR162W | hypothetical protein | 0.021 | |
| YOL038C-A | hypothetical protein | 0.020 | |
| PRS2 | Prs2p | 0.020 | |
| URA3 | Ura3p | 0.020 | |
| ARP10 | Arp10p | 0.020 | |
| TAD2 | Tad2p | 0.019 | |
| HXT3 | Hxt3p | 0.018 | |
| YPL068C | hypothetical protein | 0.017 | |
| YPR157W | hypothetical protein | 0.017 | |
| YIR035C | hypothetical protein | 0.017 | |
| YAR066W | hypothetical protein | 0.017 | |
| TCA17 | Tca17p | 0.016 | |
| GYL1 | Gyl1p | 0.016 | |
| AQY2 | Aqy2p | 0.016 | |
| YJL181W | hypothetical protein | 0.016 | |
| ATP6 | Atp6p | 0.016 | |
| MF(ALPHA)2 | Mf(alpha)2p | 0.015 | |
| HO | Hop | 0.015 | |
| SPL2 | Spl2p | 0.015 | |
| AUA1 | Aua1p | 0.015 | |
| YLR419W | hypothetical protein | 0.015 | |
| YLR040C | hypothetical protein | 0.014 | |
| ZPS1 | Zps1p | 0.014 | |
| YOL013W-A | hypothetical protein | 0.014 | |
| FMT1 | Fmt1p | 0.014 | |
| HPF1 | Hpf1p | 0.014 | |
| SCM4 | Scm4p | 0.013 | |
| YBR013C | hypothetical protein | 0.013 | |
| ATO3 | Ato3p | 0.013 | |
| YLR363W-A | hypothetical protein | 0.012 | |
| AQR1 | Aqr1p | 0.012 | |
| YLR126C | hypothetical protein | 0.012 | |
| FUI1 | Fui1p | 0.012 | |
| MET8 | Met8p | 0.012 | |
| YLL053C | hypothetical protein | 0.012 | |
| KAP104 | Kap104p | 0.012 | |
| ALT2 | Alt2p | 0.012 | |
| SWC7 | Swc7p | 0.011 | |
| BIO2 | Bio2p | 0.011 | |
| YHB1 | Yhb1p | 0.011 | |
| YAL037C-A | hypothetical protein | 0.011 | |
| YPR096C | hypothetical protein | 0.011 | |
| YAL064W | hypothetical protein | 0.011 | |
| RRT5 | Rrt5p | 0.011 | |
| PTR2 | Ptr2p | 0.011 | |
| DPH5 | Dph5p | 0.011 | |
| YGR283C | hypothetical protein | 0.011 | |
| URH1 | Urh1p | 0.011 | |
| EFM1 | Efm1p | 0.011 | |
| YPL067C | hypothetical protein | 0.011 | |
| OPT2 | Opt2p | 0.011 | |
| HLR1 | Hlr1p | 0.011 | |
| RNP1 | Rnp1p | 0.011 | |
| YKR075C | hypothetical protein | 0.011 | |
| BSC1 | Bsc1p | 0.011 | |
| MMP1 | Mmp1p | 0.011 | |
| COS12 | Cos12p | 0.011 | |
| YOL014W | hypothetical protein | 0.010 | |
| ATS1 | Ats1p | 0.010 | |
| DIC1 | Dic1p | 0.010 | |
| TYE7 | Tye7p | 0.010 | |
| CPD1 | Cpd1p | 0.010 | |
| YNL067W-B | hypothetical protein | 0.010 | |
| YGL006W-A | hypothetical protein | 0.010 | |
| NRG2 | Nrg2p | 0.010 | |
| INM1 | Inm1p | 0.010 |
