The network for 'hexose biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

hexose biosynthetic process

The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ENO1 Eno1p 0.988
PGK1 Pgk1p 0.979
GID7 Gid7p 0.958
TDH1 Tdh1p 0.936
VID30 Vid30p 0.919
GID8 Gid8p 0.909
ENO2 Eno2p 0.855
TDH2 Tdh2p 0.818
TPI1 Tpi1p 0.801
TDH3 Tdh3p 0.760
MOH1 Moh1p 0.684
RMD5 Rmd5p 0.640
FYV10 Fyv10p 0.567
ADH1 Adh1p 0.517
MLS1 Mls1p 0.517
PYC2 Pyc2p 0.381
HXK1 Hxk1p 0.343
ERR3 Err3p 0.342
GPM1 Gpm1p 0.289
FBA1 Fba1p 0.288
CAT8 Cat8p 0.279
VID24 Vid24p 0.276
GPH1 Gph1p 0.274
PYC1 Pyc1p 0.233
GAL83 Gal83p 0.146
TMA10 Tma10p 0.145
CIT2 Cit2p 0.138
VID28 Vid28p 0.122
ERR2 Err2p 0.121
MDH2 Mdh2p 0.116
GYL1 Gyl1p 0.106
EMI2 Emi2p 0.104
FBP1 Fbp1p 0.103
PFK2 Pfk2p 0.094
RDS2 Rds2p 0.088
COX5B Cox5bp 0.077
BDH1 Bdh1p 0.077
HUG1 Hug1p 0.076
CDC19 Cdc19p 0.064
GPT2 Gpt2p 0.062
CAR1 Car1p 0.060
NMT1 Nmt1p 0.060
EMI5 Emi5p 0.058
YGR017W hypothetical protein 0.056
NCE103 Nce103p 0.055
ABM1 Abm1p 0.052
YHR009C hypothetical protein 0.052
THO2 Tho2p 0.048
GLN1 Gln1p 0.048
YDR186C hypothetical protein 0.047
GTO3 Gto3p 0.047
ICL1 Icl1p 0.047
OSH2 Osh2p 0.044
PDI1 Pdi1p 0.044
YGR205W hypothetical protein 0.043
ERT1 Ert1p 0.042
HEF3 Hef3p 0.041
ICY1 Icy1p 0.040
LEE1 Lee1p 0.040
CPD1 Cpd1p 0.038
DBP1 Dbp1p 0.038
SRD1 Srd1p 0.037
ERR1 Err1p 0.037
SAK1 Sak1p 0.036
ALD4 Ald4p 0.035
TIP1 Tip1p 0.035
OYE2 Oye2p 0.034
SUC2 Suc2p 0.034
RGI1 Rgi1p 0.034
YLR162W hypothetical protein 0.033
YLR264C-A hypothetical protein 0.033
SAP4 Sap4p 0.032
YOL013W-A hypothetical protein 0.032
FMS1 Fms1p 0.032
YKL187C hypothetical protein 0.032
STP4 Stp4p 0.031
YAT2 Yat2p 0.031
LEU2 Leu2p 0.031
SIP2 Sip2p 0.031
ADR1 Adr1p 0.031
FMP10 Fmp10p 0.031
YOL014W hypothetical protein 0.031
YAP6 Yap6p 0.030
UBP11 Ubp11p 0.030
RAS2 Ras2p 0.029
PGM2 Pgm2p 0.029
CTR3 Ctr3p 0.029
YEL023C hypothetical protein 0.028
HSP33 Hsp33p 0.028
APA1 Apa1p 0.028
YOL038C-A hypothetical protein 0.028
NUT2 Nut2p 0.028
STB2 Stb2p 0.028
AUS1 Aus1p 0.027
CRC1 Crc1p 0.026
LAT1 Lat1p 0.026
PGI1 Pgi1p 0.026
SUR1 Sur1p 0.025
ARP10 Arp10p 0.025
YMR210W hypothetical protein 0.025
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.298
NCOA1 nuclear receptor coactivator 1 0.268
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 0.193
CREBBP CREB binding protein 0.117
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.087
SIRT1 sirtuin 1 0.041
AR androgen receptor 0.040
PPP4R2 protein phosphatase 4, regulatory subunit 2 0.036
RXRA retinoid X receptor, alpha 0.031
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit 0.026
TADA3 transcriptional adaptor 3 0.025
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.021
CCDC101 coiled-coil domain containing 101 0.021
JUN jun proto-oncogene 0.021
NCOA6 nuclear receptor coactivator 6 0.019
ESR1 estrogen receptor 1 0.017
ULK1 unc-51-like kinase 1 (C. elegans) 0.016
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.016
FOS FBJ murine osteosarcoma viral oncogene homolog 0.014
TRIB3 tribbles homolog 3 (Drosophila) 0.013
DDIT3 DNA-damage-inducible transcript 3 0.013
GHR growth hormone receptor 0.012
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.011
ACACA acetyl-CoA carboxylase alpha 0.011
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.011
EP300 E1A binding protein p300 0.011
TTR transthyretin 0.011
SKP1 S-phase kinase-associated protein 1 0.010
MED25 mediator complex subunit 25 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.997
Per2 period homolog 2 (Drosophila) 0.988
Per1 period homolog 1 (Drosophila) 0.868
Lepr leptin receptor 0.867
C1qc complement component 1, q subcomponent, C chain 0.863
Cry2 cryptochrome 2 (photolyase-like) 0.826
Insr insulin receptor 0.821
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.718
Clk4 CDC like kinase 4 0.695
Irs2 insulin receptor substrate 2 0.693
Jun Jun oncogene 0.605
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.578
Lep leptin 0.573
Tgfb1 transforming growth factor, beta 1 0.563
Clock circadian locomotor output cycles kaput 0.490
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.481
Mup19 major urinary protein 19 0.473
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.466
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.449
Hif1a hypoxia inducible factor 1, alpha subunit 0.426
Mup3 major urinary protein 3 0.422
LOC100048884 novel member of the major urinary protein (Mup) gene family 0.421
C1qa complement component 1, q subcomponent, alpha polypeptide 0.412
Usp2 ubiquitin specific peptidase 2 0.411
Mup5 major urinary protein 5 0.403
Mup12 major urinary protein 12 0.377
Mup4 major urinary protein 4 0.363
Mup10 major urinary protein 10 0.351
Hnf4a hepatic nuclear factor 4, alpha 0.334
Spry4 sprouty homolog 4 (Drosophila) 0.327
Fosl2 fos-like antigen 2 0.312
Fga fibrinogen alpha chain 0.311
Trib3 tribbles homolog 3 (Drosophila) 0.309
D4Wsu53e DNA segment, Chr 4, Wayne State University 53, expressed 0.303
C1qb complement component 1, q subcomponent, beta polypeptide 0.297
Mup14 major urinary protein 14 0.282
Mup9 major urinary protein 9 0.273
Ulk1 Unc-51 like kinase 1 (C. elegans) 0.263
Mup1 major urinary protein 1 0.255
Pparg peroxisome proliferator activated receptor gamma 0.236
Serpina3c serine (or cysteine) peptidase inhibitor, clade A, member 3C 0.224
Ccnl2 cyclin L2 0.223
Prlr prolactin receptor 0.213
Ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.201
Ccnt2 cyclin T2 0.195
Thra thyroid hormone receptor alpha 0.192
Mark4 MAP/microtubule affinity-regulating kinase 4 0.191
Mup8 major urinary protein 8 0.182
Mup13 major urinary protein 13 0.181
Mup17 major urinary protein 17 0.178
Mup7 major urinary protein 7 0.170
Clk1 CDC-like kinase 1 0.160
Ppara peroxisome proliferator activated receptor alpha 0.160
Rbl2 retinoblastoma-like 2 0.155
Cidec cell death-inducing DFFA-like effector c 0.153
Csrp2bp cysteine and glycine-rich protein 2 binding protein 0.149
Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C 0.142
Csf1r colony stimulating factor 1 receptor 0.142
Tdo2 tryptophan 2,3-dioxygenase 0.138
Mup15 major urinary protein 15 0.136
Baat bile acid-Coenzyme A: amino acid N-acyltransferase 0.136
Ldha lactate dehydrogenase A 0.133
Tyrobp TYRO protein tyrosine kinase binding protein 0.131
Mup11 major urinary protein 11 0.130
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.130
Serpina1b serine (or cysteine) preptidase inhibitor, clade A, member 1B 0.125
Mup2 major urinary protein 2 0.124
Hamp hepcidin antimicrobial peptide 0.124
Dmgdh dimethylglycine dehydrogenase precursor 0.124
Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.119
C4b complement component 4B (Childo blood group) 0.118
LOC100048885 major urinary protein LOC100048885 0.116
Pgam1 phosphoglycerate mutase 1 0.115
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.115
Ren1 renin 1 structural 0.114
Agtr1a angiotensin II receptor, type 1a 0.113
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.113
Akr1c6 aldo-keto reductase family 1, member C6 0.111
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.110
Cps1 carbamoyl-phosphate synthetase 1 0.109
Uox urate oxidase 0.109
Slc7a2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.108
Sertad2 SERTA domain containing 2 0.107
Pou3f1 POU domain, class 3, transcription factor 1 0.106
Fbxl3 F-box and leucine-rich repeat protein 3 0.104
Men1 multiple endocrine neoplasia 1 0.103
Lipe lipase, hormone sensitive 0.102
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.101
Ahsg alpha-2-HS-glycoprotein 0.101
Vav2 vav 2 oncogene 0.100
Hbb-b1 hemoglobin, beta adult major chain 0.100
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.098
Ces3a carboxylesterase 3A 0.098
Cyp2c50 cytochrome P450, family 2, subfamily c, polypeptide 50 0.095
Onecut1 one cut domain, family member 1 0.095
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 0.095
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.090
Rbbp5 retinoblastoma binding protein 5 0.090
Nfil3 nuclear factor, interleukin 3, regulated 0.090
Thrsp thyroid hormone responsive SPOT14 homolog (Rattus) 0.089
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ldha lactate dehydrogenase A 0.808
Pkm2 pyruvate kinase, muscle 0.425
Aldoa aldolase A, fructose-bisphosphate 0.387
Dbp D site of albumin promoter (albumin D-box) binding protein 0.336
Tpi1 triosephosphate isomerase 1 0.325
Pgam1 phosphoglycerate mutase 1 (brain) 0.090
Gpi glucose phosphate isomerase 0.076
PVR poliovirus receptor 0.038
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.035
Eno1 enolase 1, (alpha) 0.035
Pfkm phosphofructokinase, muscle 0.033
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.033
Ak1 adenylate kinase 1 0.029
Rxrg retinoid X receptor gamma 0.029
G6pc glucose-6-phosphatase, catalytic subunit 0.028
Casp2 caspase 2 0.027
Dhrs7c dehydrogenase/reductase (SDR family) member 7C 0.024
Tecr trans-2,3-enoyl-CoA reductase 0.022
Acadl acyl-Coenzyme A dehydrogenase, long-chain 0.020
Pygm phosphorylase, glycogen, muscle 0.020
Ass1 argininosuccinate synthetase 1 0.020
LOC259246 alpha-2u globulin PGCL1 0.020
Ldhd lactate dehydrogenase D 0.019
Rad23b RAD23 homolog B (S. cerevisiae) 0.019
Foxo1 forkhead box O1 0.018
Acaa1b acetyl-Coenzyme A acyltransferase 1B 0.018
Slc37a4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.017
Mosc1 MOCO sulphurase C-terminal domain containing 1 0.017
Acsl1 acyl-CoA synthetase long-chain family member 1 0.016
Ckmt2 creatine kinase, mitochondrial 2, sarcomeric 0.016
B4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.015
Mstn myostatin 0.015
Eln elastin 0.015
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.015
Cox8b cytochrome c oxidase, subunit VIIIb 0.014
Nfix nuclear factor I/X (CCAAT-binding transcription factor) 0.014
Pxmp2 peroxisomal membrane protein 2 0.013
Tat tyrosine aminotransferase 0.013
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.013
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.013
Pdgfb platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.012
Rbbp9 retinoblastoma binding protein 9 0.012
Gstm2 glutathione S-transferase mu 2 0.012
Acot12 acyl-CoA thioesterase 12 0.012
Grinl1a glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A 0.012
Mug1 murinoglobulin 1 0.012
Nxf1 nuclear RNA export factor 1 0.012
Irf3 interferon regulatory factor 3 0.011
Tuba4a tubulin, alpha 4A 0.011
Acat1 acetyl-coenzyme A acetyltransferase 1 0.011
Ttpa tocopherol (alpha) transfer protein 0.011
Pdk2 pyruvate dehydrogenase kinase, isozyme 2 0.011
Agl amylo-1,6-glucosidase, 4-alpha-glucanotransferase 0.011
Etfdh electron-transferring-flavoprotein dehydrogenase 0.010
Fbp1 fructose-1,6-bisphosphatase 1 0.010
Azgp1 alpha-2-glycoprotein 1, zinc-binding 0.010
Tkt transketolase 0.010
Sult1c2 sulfotransferase family, cytosolic, 1C, member 2 0.010
Dio1 deiodinase, iodothyronine, type I 0.010
Myc myelocytomatosis oncogene 0.010
Mup5 major urinary protein 5 0.010