The network for 'carbon catabolite activation of transcription' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

carbon catabolite activation of transcription

A transcription regulation process in which the presence of one carbon source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GAL4 Gal4p 0.944
SSN3 Ssn3p 0.903
GAL11 Gal11p 0.822
RDS2 Rds2p 0.606
YKR015C hypothetical protein 0.515
DOT6 Dot6p 0.454
GAL3 Gal3p 0.431
MIG2 Mig2p 0.421
PIP2 Pip2p 0.413
SNF1 Snf1p 0.370
MIG1 Mig1p 0.360
SWI1 Swi1p 0.353
SNF5 Snf5p 0.346
OAF1 Oaf1p 0.340
GAL1 Gal1p 0.304
MDS3 Mds3p 0.291
GLN3 Gln3p 0.280
UBA3 Uba3p 0.276
HAP3 Hap3p 0.256
GAL80 Gal80p 0.236
CAT8 Cat8p 0.227
MIG3 Mig3p 0.214
CSR2 Csr2p 0.209
GAL10 Gal10p 0.192
SNF2 Snf2p 0.172
SFL1 Sfl1p 0.169
MSN2 Msn2p 0.156
HAL5 Hal5p 0.145
HAP4 Hap4p 0.129
HAP5 Hap5p 0.126
NRG1 Nrg1p 0.121
RIM8 Rim8p 0.120
SRB8 Srb8p 0.118
HXT3 Hxt3p 0.116
AHC1 Ahc1p 0.107
GAT2 Gat2p 0.103
CUP9 Cup9p 0.102
RTG3 Rtg3p 0.101
TOS3 Tos3p 0.100
DAL81 Dal81p 0.097
MSN4 Msn4p 0.088
ERT1 Ert1p 0.087
LYS5 Lys5p 0.084
VPS27 Vps27p 0.074
SWP82 Swp82p 0.074
ECM30 Ecm30p 0.073
HDA2 Hda2p 0.072
SSK2 Ssk2p 0.070
STL1 Stl1p 0.070
AFT1 Aft1p 0.070
SSD1 Ssd1p 0.069
ASH1 Ash1p 0.069
MSN1 Msn1p 0.066
ZRG8 Zrg8p 0.065
PHO12 Pho12p 0.063
FKH1 Fkh1p 0.057
GYL1 Gyl1p 0.055
KIC1 Kic1p 0.054
YKL187C hypothetical protein 0.053
GIP2 Gip2p 0.052
TBS1 Tbs1p 0.051
SEF1 Sef1p 0.050
HBT1 Hbt1p 0.049
YPL150W hypothetical protein 0.049
ECM22 Ecm22p 0.049
YDR186C hypothetical protein 0.047
SKS1 Sks1p 0.046
YMR102C hypothetical protein 0.045
SMP1 Smp1p 0.045
YKR075C hypothetical protein 0.044
RGS2 Rgs2p 0.044
HRK1 Hrk1p 0.044
MOT3 Mot3p 0.042
HAL1 Hal1p 0.041
FAA2 Faa2p 0.041
POG1 Pog1p 0.040
ATG29 Atg29p 0.040
SSN2 Ssn2p 0.039
HAP2 Hap2p 0.039
RLM1 Rlm1p 0.039
MBR1 Mbr1p 0.038
SUC2 Suc2p 0.038
SPT20 Spt20p 0.037
PIB1 Pib1p 0.037
STP2 Stp2p 0.037
SNF6 Snf6p 0.037
ISA1 Isa1p 0.036
SIN3 Sin3p 0.036
SNF11 Snf11p 0.035
RFX1 Rfx1p 0.035
VAC7 Vac7p 0.034
ZAP1 Zap1p 0.034
RMA1 Rma1p 0.034
RPI1 Rpi1p 0.033
ITC1 Itc1p 0.032
SRD1 Srd1p 0.032
NTO1 Nto1p 0.032
SGF73 Sgf73p 0.032
YNL234W hypothetical protein 0.031
IRC8 Irc8p 0.030
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
CREBBP CREB binding protein 1.000
NCOA1 nuclear receptor coactivator 1 0.998
NCOA2 nuclear receptor coactivator 2 0.983
AR androgen receptor 0.956
DDX17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 0.956
ESR1 estrogen receptor 1 0.956
KAT2B K(lysine) acetyltransferase 2B 0.926
EP300 E1A binding protein p300 0.892
MED10 mediator complex subunit 10 0.850
RARA retinoic acid receptor, alpha 0.762
NCOA3 nuclear receptor coactivator 3 0.731
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.591
NCOA6 nuclear receptor coactivator 6 0.545
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.493
SP1 Sp1 transcription factor 0.446
MED13 mediator complex subunit 13 0.419
NFYA nuclear transcription factor Y, alpha 0.380
RXRA retinoid X receptor, alpha 0.366
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.320
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.300
MED1 mediator complex subunit 1 0.291
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.263
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.262
MED25 mediator complex subunit 25 0.248
FOXO1 forkhead box O1 0.230
NCOR2 nuclear receptor corepressor 2 0.216
NCOR1 nuclear receptor corepressor 1 0.197
RALBP1 ralA binding protein 1 0.184
DDX5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 0.169
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 0.163
CREB1 cAMP responsive element binding protein 1 0.159
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.154
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.148
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.135
MED29 mediator complex subunit 29 0.129
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.111
SMAD2 SMAD family member 2 0.104
KANK2 KN motif and ankyrin repeat domains 2 0.102
MKL1 megakaryoblastic leukemia (translocation) 1 0.100
MED13L mediator complex subunit 13-like 0.097
USF1 upstream transcription factor 1 0.096
ARID1A AT rich interactive domain 1A (SWI-like) 0.091
MED14 mediator complex subunit 14 0.088
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.086
CARM1 coactivator-associated arginine methyltransferase 1 0.073
FOXO3 forkhead box O3 0.071
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.070
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.065
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.058
CCNC cyclin C 0.055
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.054
ESR2 estrogen receptor 2 (ER beta) 0.053
RUNX1 runt-related transcription factor 1 0.048
MYOCD myocardin 0.044
MED23 mediator complex subunit 23 0.043
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.041
SMAD1 SMAD family member 1 0.041
ROD1 ROD1 regulator of differentiation 1 (S. pombe) 0.040
RALGDS ral guanine nucleotide dissociation stimulator 0.038
SREBF2 sterol regulatory element binding transcription factor 2 0.037
SPOP speckle-type POZ protein 0.036
ARID1B AT rich interactive domain 1B (SWI1-like) 0.032
CDK19 cyclin-dependent kinase 19 0.032
TMOD3 tropomodulin 3 (ubiquitous) 0.029
PDPK1 3-phosphoinositide dependent protein kinase-1 0.026
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.025
PEBP4 phosphatidylethanolamine-binding protein 4 0.025
MYOD1 myogenic differentiation 1 0.025
MED26 mediator complex subunit 26 0.025
HTT huntingtin 0.025
SREBF1 sterol regulatory element binding transcription factor 1 0.025
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.025
MKL2 MKL/myocardin-like 2 0.024
LDLR low density lipoprotein receptor 0.024
MED12 mediator complex subunit 12 0.023
MYOG myogenin (myogenic factor 4) 0.023
USF2 upstream transcription factor 2, c-fos interacting 0.023
EMP3 epithelial membrane protein 3 0.022
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.022
GRIP1 glutamate receptor interacting protein 1 0.021
PBRM1 polybromo 1 0.021
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.020
FKBP8 FK506 binding protein 8, 38kDa 0.018
RXRB retinoid X receptor, beta 0.018
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.017
MED18 mediator complex subunit 18 0.017
MYST3 MYST histone acetyltransferase (monocytic leukemia) 3 0.016
KLF13 Kruppel-like factor 13 0.016
PAWR PRKC, apoptosis, WT1, regulator 0.016
RIN1 Ras and Rab interactor 1 0.015
BAG1 BCL2-associated athanogene 0.015
NRIP1 nuclear receptor interacting protein 1 0.015
DAXX death-domain associated protein 0.015
MTA3 metastasis associated 1 family, member 3 0.015
IGSF21 immunoglobin superfamily, member 21 0.015
NFYB nuclear transcription factor Y, beta 0.015
CUX1 cut-like homeobox 1 0.015
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.014
FHL2 four and a half LIM domains 2 0.014
CNOT4 CCR4-NOT transcription complex, subunit 4 0.014
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Mus musculus
Name Description Probability Func Analog Organism
Foxc1 forkhead box C1 1.000
Shh sonic hedgehog 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Pten phosphatase and tensin homolog 1.000
Bmp4 bone morphogenetic protein 4 0.999
Ctnnb1 catenin (cadherin associated protein), beta 1 0.999
Pax2 paired box gene 2 0.999
Gli3 GLI-Kruppel family member GLI3 0.997
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.992
Sox9 SRY-box containing gene 9 0.991
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.987
Tbx1 T-box 1 0.987
Pitx2 paired-like homeodomain transcription factor 2 0.984
Eya1 eyes absent 1 homolog (Drosophila) 0.982
Pax3 paired box gene 3 0.979
Fgf8 fibroblast growth factor 8 0.975
Otx2 orthodenticle homolog 2 (Drosophila) 0.974
Rb1 retinoblastoma 1 0.969
Tgfb2 transforming growth factor, beta 2 0.966
Foxc2 forkhead box C2 0.953
Nkx2-1 NK2 homeobox 1 0.948
Foxa2 forkhead box A2 0.948
Apc adenomatosis polyposis coli 0.944
Meox2 mesenchyme homeobox 2 0.938
Tcfap2a transcription factor AP-2, alpha 0.923
Gata4 GATA binding protein 4 0.923
Lepr leptin receptor 0.920
Hmx3 H6 homeobox 3 0.915
Hoxa1 homeobox A1 0.910
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.872
Pax6 paired box gene 6 0.862
Msx1 homeobox, msh-like 1 0.846
Trp53 transformation related protein 53 0.841
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.836
Gbx2 gastrulation brain homeobox 2 0.835
Pax8 paired box gene 8 0.816
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.814
Nog noggin 0.812
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.812
Gli2 GLI-Kruppel family member GLI2 0.807
Hif1a hypoxia inducible factor 1, alpha subunit 0.801
Rxra retinoid X receptor alpha 0.799
Pbx1 pre B-cell leukemia transcription factor 1 0.788
Otx1 orthodenticle homolog 1 (Drosophila) 0.776
Esr1 estrogen receptor 1 (alpha) 0.776
Hand1 heart and neural crest derivatives expressed transcript 1 0.771
Rarb retinoic acid receptor, beta 0.766
Bcl2 B-cell leukemia/lymphoma 2 0.766
Adam17 a disintegrin and metallopeptidase domain 17 0.763
Dlx5 distal-less homeobox 5 0.762
Braf Braf transforming gene 0.733
Gsc goosecoid homeobox 0.714
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.706
Fgfr3 fibroblast growth factor receptor 3 0.696
Ptch1 patched homolog 1 0.687
Rarg retinoic acid receptor, gamma 0.678
Vegfa vascular endothelial growth factor A 0.658
Hand2 heart and neural crest derivatives expressed transcript 2 0.640
Egfr epidermal growth factor receptor 0.639
Prrx1 paired related homeobox 1 0.601
Lmx1b LIM homeobox transcription factor 1 beta 0.594
Msx2 homeobox, msh-like 2 0.590
Vangl2 vang-like 2 (van gogh, Drosophila) 0.586
Lmx1a LIM homeobox transcription factor 1 alpha 0.530
Zeb1 zinc finger E-box binding homeobox 1 0.528
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.515
Amh anti-Mullerian hormone 0.488
Runx2 runt related transcription factor 2 0.476
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.467
Isl1 ISL1 transcription factor, LIM/homeodomain 0.466
En1 engrailed 1 0.434
Efnb2 ephrin B2 0.434
Psen1 presenilin 1 0.425
Nf1 neurofibromatosis 1 0.424
Smo smoothened homolog (Drosophila) 0.407
Smad4 MAD homolog 4 (Drosophila) 0.394
Pou4f2 POU domain, class 4, transcription factor 2 0.394
Ptgs2 prostaglandin-endoperoxide synthase 2 0.389
Lhx1 LIM homeobox protein 1 0.362
Foxa1 forkhead box A1 0.345
Kit kit oncogene 0.329
Hoxa2 homeobox A2 0.329
Foxe3 forkhead box E3 0.327
Jag1 jagged 1 0.326
Hoxd3 homeobox D3 0.317
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.317
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.314
Raf1 v-raf-leukemia viral oncogene 1 0.295
Kiss1 KiSS-1 metastasis-suppressor 0.294
Hoxa3 homeobox A3 0.291
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.288
Bmp7 bone morphogenetic protein 7 0.287
Tgfbr2 transforming growth factor, beta receptor II 0.287
Pax9 paired box gene 9 0.278
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.275
Rara retinoic acid receptor, alpha 0.246
Myod1 myogenic differentiation 1 0.243
Fgfr1 fibroblast growth factor receptor 1 0.241
Smad3 MAD homolog 3 (Drosophila) 0.230
Emx2 empty spiracles homolog 2 (Drosophila) 0.228
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Rattus norvegicus
Name Description Probability Func Analog Organism
Junb jun B proto-oncogene 0.137
Ptp4a2 protein tyrosine phosphatase 4a2 0.095
Cdc34 cell division cycle 34 homolog (S. cerevisiae) 0.077
Pctk1 PCTAIRE protein kinase 1 0.069
Btg2 BTG family, member 2 0.069
Dusp1 dual specificity phosphatase 1 0.069
Atf3 activating transcription factor 3 0.056
Fos FBJ osteosarcoma oncogene 0.055
Ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.053
Thop1 thimet oligopeptidase 1 0.047
Klf6 Kruppel-like factor 6 0.044
Klf4 Kruppel-like factor 4 (gut) 0.043
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.036
Akt1 v-akt murine thymoma viral oncogene homolog 1 0.034
Clcn3 chloride channel 3 0.027
Mrpl38 mitochondrial ribosomal protein L38 0.027
Zfp91 zinc finger protein 91 0.026
Csnk1g2 casein kinase 1, gamma 2 0.024
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.023
Vegfb vascular endothelial growth factor B 0.021
Ccnd2 cyclin D2 0.020
Epn1 Epsin 1 0.019
Ubtf upstream binding transcription factor, RNA polymerase I 0.019
Gsk3b glycogen synthase kinase 3 beta 0.018
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.017
Rab14 RAB14, member RAS oncogene family 0.017
Rab1b RAB1B, member RAS oncogene family 0.017
Ube2m ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) 0.017
Safb scaffold attachment factor B 0.016
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.016
Set SET nuclear oncogene 0.015
Errfi1 ERBB receptor feedback inhibitor 1 0.015
Scaf1 SR-related CTD-associated factor 1 0.015
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform 0.015
Arf5 ADP-ribosylation factor 5 0.015
Nudt3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.014
Git1 G protein-coupled receptor kinase interacting ArfGAP 1 0.014
Rhob ras homolog gene family, member B 0.014
Dusp6 dual specificity phosphatase 6 0.014
Tor1aip1 torsin A interacting protein 1 0.013
Fkbp4 FK506 binding protein 4 0.012
Rgs19 regulator of G-protein signaling 19 0.012
Rgs12 regulator of G-protein signaling 12 0.012
Egr1 early growth response 1 0.012
Hk1 hexokinase 1 0.012
Puf60 poly-U binding splicing factor 60 0.012
Epn2 epsin 2 0.011
Gsr glutathione reductase 0.011
Ccdc124 coiled-coil domain containing 124 0.011
Tmed5 transmembrane emp24 protein transport domain containing 5 0.011
Ednrb endothelin receptor type B 0.011
Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.011
Fgfr1 Fibroblast growth factor receptor 1 0.011
Pppde1 PPPDE peptidase domain containing 1 0.010
Eif5b eukaryotic translation initiation factor 5B 0.010
Fam100a family with sequence similarity 100, member A 0.010
LOC100360174 lysM and putative peptidoglycan-binding domain-containing protein 3-like 0.010
Klf9 Kruppel-like factor 9 0.010
Hspa1a heat shock 70kD protein 1A 0.010
Sgta small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.010
Cops7a COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) 0.010
Hspbp1 HSPA binding protein, cytoplasmic cochaperone 1 0.010