The network for 'purine nucleoside triphosphate biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

purine nucleoside triphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ATP4 Atp4p 1.000
ATP1 Atp1p 0.999
ATP5 Atp5p 0.985
ATP20 Atp20p 0.981
ATP18 Atp18p 0.969
ATP3 Atp3p 0.950
ATP2 Atp2p 0.948
ATP17 Atp17p 0.747
ATP16 Atp16p 0.741
ATP15 Atp15p 0.703
ATP14 Atp14p 0.448
ATP7 Atp7p 0.447
QCR2 Qcr2p 0.402
COX9 Cox9p 0.376
PET9 Pet9p 0.338
INH1 Inh1p 0.273
NDE1 Nde1p 0.212
QCR6 Qcr6p 0.179
MIR1 Mir1p 0.156
ATP6 Atp6p 0.147
LSC1 Lsc1p 0.126
TIM11 Tim11p 0.123
COX4 Cox4p 0.089
COX7 Cox7p 0.066
RPM2 Rpm2p 0.051
COX8 Cox8p 0.046
ATP8 Atp8p 0.045
HOR2 Hor2p 0.035
YPL247C hypothetical protein 0.034
SRD1 Srd1p 0.032
PRY1 Pry1p 0.032
OLI1 F0-ATP synthase subunit c (ATPase-associated proteolipid), encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP2 0.030
HEM15 Hem15p 0.029
YLR162W hypothetical protein 0.027
YLR264C-A hypothetical protein 0.026
CUP1-1 Cup1-1p 0.026
YOL038C-A hypothetical protein 0.024
LEU2 Leu2p 0.023
YAR068W hypothetical protein 0.023
ARP10 Arp10p 0.023
LEU5 Leu5p 0.022
YJR120W hypothetical protein 0.022
UPS3 Ups3p 0.022
GYL1 Gyl1p 0.022
TPO4 Tpo4p 0.021
YDL241W hypothetical protein 0.020
SPL2 Spl2p 0.020
AGC1 Agc1p 0.020
MER1 Mer1p 0.019
CAM1 Cam1p 0.019
ALD4 Ald4p 0.019
HXT7 Hxt7p 0.019
ZPS1 Zps1p 0.018
YLR042C hypothetical protein 0.018
HXT3 Hxt3p 0.018
AUA1 Aua1p 0.017
KNH1 Knh1p 0.017
CPD1 Cpd1p 0.017
YPR157W hypothetical protein 0.017
YAR066W hypothetical protein 0.016
YBR013C hypothetical protein 0.016
YCL057C-A hypothetical protein 0.016
YPL014W hypothetical protein 0.015
GDH1 Gdh1p 0.014
ARG8 Arg8p 0.014
COX6 Cox6p 0.014
ICS2 Ics2p 0.014
FMT1 Fmt1p 0.014
HPF1 Hpf1p 0.013
MF(ALPHA)2 Mf(alpha)2p 0.013
YOL014W hypothetical protein 0.013
HAP4 Hap4p 0.013
YOL013W-A hypothetical protein 0.013
PIR1 Pir1p 0.012
COX2 Cox2p 0.012
YML003W hypothetical protein 0.012
CWP1 Cwp1p 0.012
BSC1 Bsc1p 0.012
SNO3 Sno3p 0.012
OPT2 Opt2p 0.012
IZH4 Izh4p 0.012
MDH1 Mdh1p 0.012
YPL067C hypothetical protein 0.012
YIR035C hypothetical protein 0.012
YPR096C hypothetical protein 0.012
YLR040C hypothetical protein 0.011
BI4 Bi4p 0.011
SCM4 Scm4p 0.011
MDM36 Mdm36p 0.011
DIC1 Dic1p 0.011
TIR3 Tir3p 0.011
PLB1 Plb1p 0.011
YJL107C hypothetical protein 0.010
RRN5 Rrn5p 0.010
RNP1 Rnp1p 0.010
YGL006W-A hypothetical protein 0.010
YAL064W hypothetical protein 0.010
NRG2 Nrg2p 0.010
ENO2 Eno2p 0.010
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
atp-5 Protein ATP-5 0.017
atp-2 Protein ATP-2 0.016
ant-1.1 Protein ANT-1.1 0.011
isp-1 Protein ISP-1 0.011
F58F12.1 Protein F58F12.1 0.011
cyc-2.1 Protein CYC-2.1 0.010
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.525
aldocb aldolase C, fructose-bisphosphate, b 0.394
hk1 hexokinase 1 0.110
ldb3b LIM domain binding 3b 0.109
pabpc1b poly A binding protein, cytoplasmic 1 b 0.089
pgk1 phosphoglycerate kinase 1 0.077
eno1 enolase 1, (alpha) 0.073
atp5g ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9) 0.071
zgc:165344 zgc:165344 0.054
sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.053
ndufa4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 0.052
atp2a1l ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 like 0.051
got2b glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2) 0.049
gpia glucose phosphate isomerase a 0.043
pgam2 phosphoglycerate mutase 2 (muscle) 0.041
slc25a3b solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b 0.041
zgc:91930 zgc:91930 0.040
tpi1b triosephosphate isomerase 1b 0.039
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.036
tfec transcription factor EC 0.035
idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.034
zgc:92631 zgc:92631 0.034
dlst dihydrolipoamide S-succinyltransferase 0.032
zgc:152873 zgc:152873 0.031
eef2l2 eukaryotic translation elongation factor 2, like 2 0.030
atp5d ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 0.030
pvalb1 parvalbumin 1 0.030
pabpc4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.029
hccs holocytochrome c synthase 0.029
socs3b suppressor of cytokine signaling 3b 0.029
tert telomerase reverse transcriptase 0.028
pvalb4 parvalbumin 4 0.028
aco2 aconitase 2, mitochondrial 0.028
pvalb2 parvalbumin 2 0.026
mdh1b malate dehydrogenase 1b, NAD (soluble) 0.025
jun jun proto-oncogene 0.025
pvalb3 parvalbumin 3 0.024
zgc:111961 zgc:111961 0.024
anxa11a annexin A11a 0.023
zgc:63976 zgc:63976 0.022
casq2 calsequestrin 2 0.022
myl10 myosin, light chain 10, regulatory 0.022
sucla2 succinate-CoA ligase, ADP-forming, beta subunit 0.021
tmem38a transmembrane protein 38A 0.020
zgc:64133 zgc:64133 0.020
LOC560944 6-phosphofructokinase type C-like 0.020
ldb3a LIM-domain binding factor 3a 0.019
slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 0.018
pdha1a pyruvate dehydrogenase (lipoamide) alpha 1a 0.018
hspa9 heat shock protein 9 0.018
mibp2 muscle-specific beta 1 integrin binding protein 2 0.018
pdhx pyruvate dehydrogenase complex, component X 0.018
ogdh oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.017
tomm34 translocase of outer mitochondrial membrane 34 0.017
mybpc2b myosin binding protein C, fast type b 0.017
impdh1b inosine 5'-phosphate dehydrogenase 1b 0.016
tyrp1b tyrosinase-related protein 1b 0.016
cox6a1 cytochrome c oxidase subunit VIa polypeptide 1 0.016
mycl1b v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) b 0.016
myl1 myosin, light chain 1, alkali; skeletal, fast 0.015
rlbp1b retinaldehyde binding protein 1b 0.015
lhcgr luteinizing hormone/choriogonadotropin receptor 0.015
LOC555482 tachykinin receptor 3-like 0.015
mars methionine-tRNA synthetase 0.014
zgc:100919 zgc:100919 0.014
pygmb phosphorylase, glycogen (muscle) b 0.014
fxr2 fragile X mental retardation, autosomal homolog 2 0.014
prdx4 peroxiredoxin 4 0.014
cox8a cytochrome c oxidase subunit 8a 0.014
ucp3 uncoupling protein 3 0.014
vdac2 voltage-dependent anion channel 2 0.014
socs3a suppressor of cytokine signaling 3a 0.014
pgp phosphoglycolate phosphatase 0.013
metap1 methionyl aminopeptidase 1 0.013
tkt transketolase 0.013
dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) 0.013
keap1a kelch-like ECH-associated protein 1a 0.013
aox3 aldehyde oxidase 3 0.013
rars arginyl-tRNA synthetase 0.013
ldha lactate dehydrogenase A4 0.013
slc25a25a solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a 0.013
eef2k elongation factor-2 kinase 0.013
zgc:162329 zgc:162329 0.013
pcsk5a proprotein convertase subtilisin/kexin type 5a 0.013
ssb Sjogren syndrome antigen B (autoantigen La) 0.013
zfp36l1b zinc finger protein 36, C3H type-like 1b 0.013
rpl3 ribosomal protein L3 0.013
cav3 caveolin 3 0.012
mylz3 myosin, light polypeptide 3, skeletal muscle 0.012
junb jun B proto-oncogene 0.012
dhtkd1 dehydrogenase E1 and transketolase domain containing 1 0.012
zgc:101724 zgc:101724 0.012
gclc glutamate-cysteine ligase, catalytic subunit 0.012
myca myelocytomatosis oncogene a 0.012
hoxa9b homeo box A9b 0.012
srfl serum response factor like 0.012
bysl bystin-like 0.011
zgc:77235 zgc:77235 0.011
atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.011
pgam1b phosphoglycerate mutase 1b 0.011
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
blw bellwether 0.102
Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1 0.050
ATPsyn-b ATP synthase, subunit b 0.047
CG10664 CG10664 gene product from transcript CG10664-RB 0.042
l(1)G0230 lethal (1) G0230 0.039
GlyP Glycogen phosphorylase 0.022
ATPsyn-gamma ATP synthase-gamma chain 0.022
Pglym78 Phosphoglyceromutase 0.015
CG11876 CG11876 gene product from transcript CG11876-RA 0.015
Pgk Phosphoglycerate kinase 0.015
Cyt-c-p Cytochrome c proximal 0.014
porin CG6647 gene product from transcript CG6647-RA 0.014
Eno Enolase 0.014
CG3321 CG3321 gene product from transcript CG3321-RC 0.013
Scsalpha Succinyl coenzyme A synthetase alpha subunit 0.013
CG7145 CG7145 gene product from transcript CG7145-RD 0.012
CG8709 CG8709 gene product from transcript CG8709-RK 0.011
trio CG18214 gene product from transcript CG18214-RA 0.011
levy CG17280 gene product from transcript CG17280-RA 0.011
CadN Cadherin-N 0.010
Spn27A Serpin 27A 0.010
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.597
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.369
TPI1 triosephosphate isomerase 1 0.211
PHB2 prohibitin 2 0.199
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.186
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 0.109
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.103
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.084
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 0.063
UQCRC1 ubiquinol-cytochrome c reductase core protein I 0.049
ENG endoglin 0.045
CYC1 cytochrome c-1 0.044
VDAC2 voltage-dependent anion channel 2 0.042
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.040
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.034
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.031
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 0.029
PGK1 phosphoglycerate kinase 1 0.025
EIF4A1 eukaryotic translation initiation factor 4A1 0.025
GPI glucose-6-phosphate isomerase 0.024
ESRRG estrogen-related receptor gamma 0.022
PPARG peroxisome proliferator-activated receptor gamma 0.020
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.019
IMMT inner membrane protein, mitochondrial 0.019
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.017
FSTL1 follistatin-like 1 0.017
QARS glutaminyl-tRNA synthetase 0.017
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 0.016
ENO1 enolase 1, (alpha) 0.015
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 0.014
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.014
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 0.014
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 0.014
COX5A cytochrome c oxidase subunit Va 0.013
EIF3K eukaryotic translation initiation factor 3, subunit K 0.012
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.011
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 0.011
MRPL37 mitochondrial ribosomal protein L37 0.011
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.011
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.010
DDT D-dopachrome tautomerase 0.010
KIFAP3 kinesin-associated protein 3 0.010
CCDC90B coiled-coil domain containing 90B 0.010
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.540
Tpi1 triosephosphate isomerase 1 0.309
Gpi1 glucose phosphate isomerase 1 0.185
Pkm2 pyruvate kinase, muscle 0.140
Gm5506 predicted gene 5506 0.083
Pgk1 phosphoglycerate kinase 1 0.071
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 0.068
Aldoa aldolase A, fructose-bisphosphate 0.062
Ldha lactate dehydrogenase A 0.045
Pnp2 purine-nucleoside phosphorylase 2 0.044
Trp53 transformation related protein 53 0.028
Mdh2 malate dehydrogenase 2, NAD (mitochondrial) 0.025
Cs citrate synthase 0.024
Aco2 aconitase 2, mitochondrial 0.021
Il6st interleukin 6 signal transducer 0.018
Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit 0.018
Pgam1 phosphoglycerate mutase 1 0.017
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.016
Lepr leptin receptor 0.015
Pparg peroxisome proliferator activated receptor gamma 0.014
Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 0.013
Pfkl phosphofructokinase, liver, B-type 0.011
Cyc1 cytochrome c-1 0.010
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 0.412
Aldoa aldolase A, fructose-bisphosphate 0.089
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.052
Slc25a4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.051
Mdh1 malate dehydrogenase 1, NAD (soluble) 0.051
Psma7 proteasome (prosome, macropain) subunit, alpha type 7 0.042
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.035
Nhp2 NHP2 ribonucleoprotein homolog (yeast) 0.025
Mrps7 mitochondrial ribosomal protein S7 0.024
Oaz1 ornithine decarboxylase antizyme 1 0.024
Cox4i1 cytochrome c oxidase subunit IV isoform 1 0.021
Ldha lactate dehydrogenase A 0.014
Atp5g3 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) 0.014
Fabp5 fatty acid binding protein 5, epidermal 0.012
Ppia peptidylprolyl isomerase A (cyclophilin A) 0.011
Pgam1 phosphoglycerate mutase 1 (brain) 0.010