The network for 'aspartate family amino acid metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

aspartate family amino acid metabolic process

The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
THR4 Thr4p 0.982
LYS20 Lys20p 0.964
ASP3-3 Asp3-3p 0.925
ASP3-4 Asp3-4p 0.907
ASP3-2 Asp3-2p 0.891
ASP3-1 Asp3-1p 0.865
MET13 Met13p 0.790
ALD5 Ald5p 0.772
LYS21 Lys21p 0.668
MET6 Met6p 0.651
MET14 Met14p 0.621
ASN1 Asn1p 0.616
MET12 Met12p 0.582
ARO9 Aro9p 0.541
MMP1 Mmp1p 0.507
ERG13 Erg13p 0.469
MET28 Met28p 0.439
MET16 Met16p 0.409
MET3 Met3p 0.375
LYS4 Lys4p 0.356
LEU9 Leu9p 0.351
KRS1 Krs1p 0.328
LYS9 Lys9p 0.308
ARO2 Aro2p 0.301
HOM3 Hom3p 0.256
ASN2 Asn2p 0.250
ARO8 Aro8p 0.216
MDE1 Mde1p 0.187
REE1 Ree1p 0.181
MET10 Met10p 0.176
SAM2 Sam2p 0.170
ERV46 Erv46p 0.155
YCR051W hypothetical protein 0.142
GGC1 Ggc1p 0.141
GND1 Gnd1p 0.139
ZRC1 Zrc1p 0.139
ARO4 Aro4p 0.139
RIB3 Rib3p 0.111
SAM4 Sam4p 0.110
RMD6 Rmd6p 0.108
AIM27 Aim27p 0.108
FOL2 Fol2p 0.104
MUP3 Mup3p 0.103
CCT8 Cct8p 0.103
PHO11 Pho11p 0.103
ADH6 Adh6p 0.096
SUL2 Sul2p 0.096
PYC1 Pyc1p 0.095
IMD2 Imd2p 0.093
YMR321C hypothetical protein 0.087
YMR130W hypothetical protein 0.086
SER33 Ser33p 0.085
STR3 Str3p 0.080
ARG5,6 Arg5,6p 0.079
HOM6 Hom6p 0.077
MET2 Met2p 0.077
LYS12 Lys12p 0.073
TSC3 Tsc3p 0.073
YJR111C hypothetical protein 0.072
IRC7 Irc7p 0.070
GUS1 Gus1p 0.069
CBR1 Cbr1p 0.067
YLR179C hypothetical protein 0.067
YMC1 Ymc1p 0.064
ARG8 Arg8p 0.064
SEO1 Seo1p 0.061
HOM2 Hom2p 0.060
YNG1 Yng1p 0.059
SAM3 Sam3p 0.058
MVD1 Mvd1p 0.058
FUI1 Fui1p 0.058
HOR2 Hor2p 0.058
LOT5 Lot5p 0.056
FPR1 Fpr1p 0.055
TUM1 Tum1p 0.054
BAT1 Bat1p 0.053
LYP1 Lyp1p 0.053
YLR264C-A hypothetical protein 0.053
OPT1 Opt1p 0.052
MMF1 Mmf1p 0.051
YHM2 Yhm2p 0.050
YLR162W hypothetical protein 0.050
SPE3 Spe3p 0.049
URA3 Ura3p 0.049
RPE1 Rpe1p 0.048
URA2 Ura2p 0.047
HTS1 Hts1p 0.047
YIR035C hypothetical protein 0.047
SRD1 Srd1p 0.047
SSM4 Ssm4p 0.046
TRP3 Trp3p 0.046
GPM1 Gpm1p 0.044
ADE17 Ade17p 0.043
RBG1 Rbg1p 0.043
MER1 Mer1p 0.043
SER1 Ser1p 0.043
YOL038C-A hypothetical protein 0.042
HXT3 Hxt3p 0.041
ART5 Art5p 0.041
CUP1-1 Cup1-1p 0.041
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Immt inner membrane protein, mitochondrial 0.889
Shmt2 serine hydroxymethyltransferase 2 (mitochondrial) 0.405
Mdh1 malate dehydrogenase 1, NAD (soluble) 0.379
Gjb1 gap junction protein, beta 1 0.233
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.156
Dok1 docking protein 1 0.144
Bhmt2 betaine-homocysteine methyltransferase 2 0.137
Atp5g1 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9) 0.111
Cbs cystathionine beta-synthase 0.108
Nadk NAD kinase 0.092
Got1 glutamate oxaloacetate transaminase 1, soluble 0.091
Got2 glutamate oxaloacetate transaminase 2, mitochondrial 0.087
Gsta2 glutathione S-transferase, alpha 2 (Yc2) 0.082
Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit 0.080
Fga fibrinogen alpha chain 0.071
Tdo2 tryptophan 2,3-dioxygenase 0.071
Apom apolipoprotein M 0.070
Gldc glycine decarboxylase 0.058
Tmem30b transmembrane protein 30B 0.057
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.056
Vdac1 voltage-dependent anion channel 1 0.054
Mif macrophage migration inhibitory factor 0.053
Ppara peroxisome proliferator activated receptor alpha 0.053
Hpd 4-hydroxyphenylpyruvic acid dioxygenase 0.052
Eif5a eukaryotic translation initiation factor 5A 0.052
Rgn regucalcin 0.051
Serpina1a serine (or cysteine) peptidase inhibitor, clade A, member 1A 0.049
Apoc1 apolipoprotein C-I 0.045
Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 0.044
Esrp2 epithelial splicing regulatory protein 2 0.043
Nudc nuclear distribution gene C homolog (Aspergillus) 0.040
Tuba4a tubulin, alpha 4A 0.038
Smyd5 SET and MYND domain containing 5 0.037
Slc35a4 solute carrier family 35, member A4 0.037
Gsta3 glutathione S-transferase, alpha 3 0.036
Apoa2 apolipoprotein A-II 0.036
Slc13a3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 0.036
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 0.036
Gc group specific component 0.034
Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 0.034
Ttr transthyretin 0.033
Hpn hepsin 0.033
Klf15 Kruppel-like factor 15 0.032
Slc47a1 solute carrier family 47, member 1 0.031
Slc6a13 solute carrier family 6 (neurotransmitter transporter, GABA), member 13 0.031
Ciapin1 cytokine induced apoptosis inhibitor 1 0.030
Aldh1l1 aldehyde dehydrogenase 1 family, member L1 0.029
Gnmt glycine N-methyltransferase 0.029
Mettl7a1 methyltransferase like 7A1 0.028
Car14 carbonic anhydrase 14 0.028
Mpzl2 myelin protein zero-like 2 0.028
Mat1a methionine adenosyltransferase I, alpha 0.028
Sardh sarcosine dehydrogenase 0.027
Shmt1 serine hydroxymethyltransferase 1 (soluble) 0.027
Slc7a2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.026
Proc protein C 0.025
Cdk18 cyclin-dependent kinase 18 0.025
Csnk2b casein kinase 2, beta polypeptide 0.024
Elovl2 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 0.024
F13b coagulation factor XIII, beta subunit 0.024
C8g complement component 8, gamma polypeptide 0.023
Galm galactose mutarotase 0.023
Dynlt1f dynein light chain Tctex-type 1F 0.023
Rbp4 retinol binding protein 4, plasma 0.022
Qprt quinolinate phosphoribosyltransferase 0.022
Il1f10 interleukin 1 family, member 10 0.022
Pah phenylalanine hydroxylase 0.021
Rpl12 ribosomal protein L12 0.021
Acy1 aminoacylase 1 0.021
Bcat1 branched chain aminotransferase 1, cytosolic 0.021
Alg3 asparagine-linked glycosylation 3 homolog (yeast, alpha-1,3-mannosyltransferase) 0.021
Cyp2c50 cytochrome P450, family 2, subfamily c, polypeptide 50 0.021
Sars2 seryl-aminoacyl-tRNA synthetase 2 0.020
Prodh proline dehydrogenase 0.020
Srd5a2 steroid 5 alpha-reductase 2 0.019
Tchh trichohyalin 0.019
Aadat aminoadipate aminotransferase 0.019
Igfals insulin-like growth factor binding protein, acid labile subunit 0.019
Kng1 kininogen 1 0.019
Rdh7 retinol dehydrogenase 7 0.019
Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 0.019
Ahsg alpha-2-HS-glycoprotein 0.018
Nudcd3 NudC domain containing 3 0.018
Ak4 adenylate kinase 4 0.018
Cd70 CD70 antigen 0.017
Mlxipl MLX interacting protein-like 0.017
Thrsp thyroid hormone responsive SPOT14 homolog (Rattus) 0.017
Adhfe1 alcohol dehydrogenase, iron containing, 1 0.016
Eaf2 ELL associated factor 2 0.016
Pcsk6 proprotein convertase subtilisin/kexin type 6 0.016
Golt1a golgi transport 1 homolog A (S. cerevisiae) 0.016
Fdxr ferredoxin reductase 0.016
Mkrn2 makorin, ring finger protein, 2 0.016
Arhgap8 Rho GTPase activating protein 8 0.016
Bhmt betaine-homocysteine methyltransferase 0.016
Aass aminoadipate-semialdehyde synthase 0.016
Agxt2l1 alanine-glyoxylate aminotransferase 2-like 1 0.015
Ggt1 gamma-glutamyltransferase 1 0.015
Haao 3-hydroxyanthranilate 3,4-dioxygenase 0.015
Dgat2 diacylglycerol O-acyltransferase 2 0.015
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Rattus norvegicus
Name Description Probability Func Analog Organism
Vdac1 voltage-dependent anion channel 1 0.303
Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.236
Auh AU RNA binding protein/enoyl-coenzyme A hydratase 0.035
Nenf neuron derived neurotrophic factor 0.030
Yars tyrosyl-tRNA synthetase 0.030
Gars glycyl-tRNA synthetase 0.023
Hpd 4-hydroxyphenylpyruvate dioxygenase 0.021
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.019
Acot12 acyl-CoA thioesterase 12 0.019
Phgdh phosphoglycerate dehydrogenase 0.016
Dlst dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.015
Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 0.015
Pfkm phosphofructokinase, muscle 0.014
Psat1 phosphoserine aminotransferase 1 0.013
Trmt61a tRNA methyltransferase 61 homolog A (S. cerevisiae) 0.013
Anxa7 annexin A7 0.013
Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 0.013
Cars cysteinyl-tRNA synthetase 0.012
Rup2 urinary protein 2 0.012
Akr1c12 aldo-keto reductase family 1, member C12 0.012
Mfn2 mitofusin 2 0.012
Aldh18a1 aldehyde dehydrogenase 18 family, member A1 0.012
RGD1310348 similar to Ser/Thr-rich protein T10 in DGCR region 0.011
Alas1 aminolevulinate, delta-, synthase 1 0.011
Fabp1 fatty acid binding protein 1, liver 0.011
Dio1 deiodinase, iodothyronine, type I 0.011
Pycr1 pyrroline-5-carboxylate reductase 1 0.011
Guca2a guanylate cyclase activator 2a (guanylin) 0.011
Gchfr GTP cyclohydrolase I feedback regulator 0.010
Alg5 asparagine-linked glycosylation 5, dolichyl-phosphate beta-glucosyltransferase homolog (S. cerevisiae) 0.010