The network for 'rrna modification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

rrna modification

The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically.

Name Description Probability Func Analog Organism
CBF5 Cbf5p 0.650
PXR1 Pxr1p 0.369
MTO1 Mto1p 0.337
PUS1 Pus1p 0.329
NAF1 Naf1p 0.287
YBL081W hypothetical protein 0.286
TSR1 Tsr1p 0.284
MER1 Mer1p 0.255
GAR1 Gar1p 0.237
PRP28 Prp28p 0.190
YLR264C-A hypothetical protein 0.176
IMD4 Imd4p 0.175
YCR051W hypothetical protein 0.172
MAK16 Mak16p 0.162
SUA5 Sua5p 0.161
BCP1 Bcp1p 0.157
NHP2 Nhp2p 0.147
ENP1 Enp1p 0.147
UTP18 Utp18p 0.146
SWM2 Swm2p 0.146
URA3 Ura3p 0.145
LTV1 Ltv1p 0.143
NOP6 Nop6p 0.143
SRD1 Srd1p 0.143
DIP2 Dip2p 0.136
FYV7 Fyv7p 0.133
LEU2 Leu2p 0.129
GFD2 Gfd2p 0.128
YOL038C-A hypothetical protein 0.123
ARG8 Arg8p 0.121
YGL006W-A hypothetical protein 0.115
YLR162W hypothetical protein 0.112
YNL018C hypothetical protein 0.112
HMS2 Hms2p 0.109
FCY21 Fcy21p 0.107
NRD1 Nrd1p 0.107
ATP6 Atp6p 0.106
ARP10 Arp10p 0.104
YBR013C hypothetical protein 0.104
NOP10 Nop10p 0.101
RIO2 Rio2p 0.101
RKI1 Rki1p 0.099
RRP5 Rrp5p 0.099
PRS2 Prs2p 0.097
YOL013W-A hypothetical protein 0.097
RRP14 Rrp14p 0.096
YAL037C-A hypothetical protein 0.096
YPR157W hypothetical protein 0.096
YNL067W-B hypothetical protein 0.096
HO Hop 0.095
SCM4 Scm4p 0.095
YDR034C-A hypothetical protein 0.094
ZPS1 Zps1p 0.093
YLR042C hypothetical protein 0.092
LOT5 Lot5p 0.088
HPF1 Hpf1p 0.088
RRS1 Rrs1p 0.087
MTG2 Mtg2p 0.086
YGL235W hypothetical protein 0.086
DUS1 Dus1p 0.086
AST1 Ast1p 0.086
YNL162W-A hypothetical protein 0.085
YLR040C hypothetical protein 0.084
ALT2 Alt2p 0.082
CHA1 Cha1p 0.082
NOP8 Nop8p 0.082
RPS13 Rps13p 0.081
COS12 Cos12p 0.081
TSC3 Tsc3p 0.079
YPL067C hypothetical protein 0.079
PTR2 Ptr2p 0.079
HEM3 Hem3p 0.079
YAR068W hypothetical protein 0.079
YNL024C hypothetical protein 0.078
PPM2 Ppm2p 0.078
YOL114C hypothetical protein 0.077
YOR293C-A hypothetical protein 0.077
YML100W-A hypothetical protein 0.076
YIL151C hypothetical protein 0.076
YLR412C-A hypothetical protein 0.076
YMR001C-A hypothetical protein 0.075
ADH2 Adh2p 0.075
UPS3 Ups3p 0.075
YCL001W-B hypothetical protein 0.075
HXT3 Hxt3p 0.074
YLR342W-A hypothetical protein 0.074
YKL068W-A hypothetical protein 0.073
YAL064W hypothetical protein 0.073
YIR035C hypothetical protein 0.073
QRI7 Qri7p 0.073
BSC1 Bsc1p 0.072
AUA1 Aua1p 0.072
PUS6 Pus6p 0.072
YLR406C-A hypothetical protein 0.071
HMRA1 Hmra1p 0.071
ICS3 Ics3p 0.071
DUS3 Dus3p 0.070
YPL216W hypothetical protein 0.070
RIM2 Rim2p 0.070
YTM1 Ytm1p 0.070
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
NOP56 NOP56 ribonucleoprotein homolog (yeast) 0.997
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 0.959
NOP58 NOP58 ribonucleoprotein homolog (yeast) 0.908
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.892
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.840
DDX21 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 0.686
FBL fibrillarin 0.661
GAR1 GAR1 ribonucleoprotein homolog (yeast) 0.619
DKC1 dyskeratosis congenita 1, dyskerin 0.579
NCL nucleolin 0.326
ODC1 ornithine decarboxylase 1 0.268
PHB2 prohibitin 2 0.180
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.163
RSL1D1 ribosomal L1 domain containing 1 0.137
NAF1 nuclear assembly factor 1 homolog (S. cerevisiae) 0.127
POLR1C polymerase (RNA) I polypeptide C, 30kDa 0.124
EBNA1BP2 EBNA1 binding protein 2 0.122
MYBBP1A MYB binding protein (P160) 1a 0.114
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.114
PA2G4 proliferation-associated 2G4, 38kDa 0.094
MKI67IP MKI67 (FHA domain) interacting nucleolar phosphoprotein 0.092
PRMT1 protein arginine methyltransferase 1 0.091
FTSJ3 FtsJ homolog 3 (E. coli) 0.083
NAT10 N-acetyltransferase 10 (GCN5-related) 0.079
MAK16 MAK16 homolog (S. cerevisiae) 0.074
LYAR Ly1 antibody reactive homolog (mouse) 0.071
NOP14 NOP14 nucleolar protein homolog (yeast) 0.070
RUVBL1 RuvB-like 1 (E. coli) 0.065
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.058
PPAN peter pan homolog (Drosophila) 0.055
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 0.052
PUS7 pseudouridylate synthase 7 homolog (S. cerevisiae) 0.050
EMG1 EMG1 nucleolar protein homolog (S. cerevisiae) 0.043
EIF3D eukaryotic translation initiation factor 3, subunit D 0.041
UTP18 UTP18, small subunit (SSU) processome component, homolog (yeast) 0.038
NXT1 NTF2-like export factor 1 0.036
C10orf2 chromosome 10 open reading frame 2 0.035
EIF3G eukaryotic translation initiation factor 3, subunit G 0.035
DPCD deleted in primary ciliary dyskinesia homolog (mouse) 0.034
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 0.029
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) 0.028
BZW2 basic leucine zipper and W2 domains 2 0.028
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.028
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) 0.027
KIAA0020 KIAA0020 0.027
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 0.025
NOP16 NOP16 nucleolar protein homolog (yeast) 0.024
KARS lysyl-tRNA synthetase 0.022
LAS1L LAS1-like (S. cerevisiae) 0.021
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 0.021
PWP1 PWP1 homolog (S. cerevisiae) 0.021
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 0.021
C12orf45 chromosome 12 open reading frame 45 0.020
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.019
LYRM4 LYR motif containing 4 0.019
SF3A3 splicing factor 3a, subunit 3, 60kDa 0.018
CHCHD8 coiled-coil-helix-coiled-coil-helix domain containing 8 0.018
RUVBL2 RuvB-like 2 (E. coli) 0.018
PUS1 pseudouridylate synthase 1 0.018
RCL1 RNA terminal phosphate cyclase-like 1 0.018
SSRP1 structure specific recognition protein 1 0.017
WDR74 WD repeat domain 74 0.016
SHQ1 SHQ1 homolog (S. cerevisiae) 0.016
SLC25A38 solute carrier family 25, member 38 0.016
CBFB core-binding factor, beta subunit 0.016
EIF3B eukaryotic translation initiation factor 3, subunit B 0.016
ALKBH2 alkB, alkylation repair homolog 2 (E. coli) 0.016
WDR3 WD repeat domain 3 0.015
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.015
PITPNB phosphatidylinositol transfer protein, beta 0.015
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 0.014
RBM28 RNA binding motif protein 28 0.014
TGS1 trimethylguanosine synthase 1 0.014
WDR43 WD repeat domain 43 0.014
RRP1B ribosomal RNA processing 1 homolog B (S. cerevisiae) 0.014
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 0.013
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 0.013
SSR1 signal sequence receptor, alpha 0.013
NIP7 nuclear import 7 homolog (S. cerevisiae) 0.013
RPIA ribose 5-phosphate isomerase A 0.012
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 0.012
RPP40 ribonuclease P/MRP 40kDa subunit 0.012
PNO1 partner of NOB1 homolog (S. cerevisiae) 0.012
PTDSS1 phosphatidylserine synthase 1 0.011
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.011
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 0.011
PCID2 PCI domain containing 2 0.010
C12orf24 chromosome 12 open reading frame 24 0.010
UCK2 uridine-cytidine kinase 2 0.010
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism