The network for 'cellular modified amino acid biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular modified amino acid biosynthetic process

The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ADE4 Ade4p 0.024
MET6 Met6p 0.021
YBR220C hypothetical protein 0.020
CDS1 Cds1p 0.019
SDS3 Sds3p 0.018
ERG7 Erg7p 0.018
LCB2 Lcb2p 0.017
ADE5,7 Ade5,7p 0.015
TGL1 Tgl1p 0.015
TRM5 Trm5p 0.014
SPE3 Spe3p 0.014
OPT1 Opt1p 0.014
ERG8 Erg8p 0.013
YGR210C hypothetical protein 0.013
CNE1 Cne1p 0.013
URA3 Ura3p 0.013
CKB1 Ckb1p 0.012
ADH6 Adh6p 0.012
BNA7 Bna7p 0.012
YML018C hypothetical protein 0.012
YLR108C hypothetical protein 0.012
EHT1 Eht1p 0.012
AST1 Ast1p 0.012
TSC3 Tsc3p 0.012
ADE13 Ade13p 0.012
RRT2 Rrt2p 0.012
IXR1 Ixr1p 0.011
YCR015C hypothetical protein 0.011
ALT1 Alt1p 0.011
CHS1 Chs1p 0.011
ADE12 Ade12p 0.011
KAP104 Kap104p 0.011
VCX1 Vcx1p 0.011
YFR016C hypothetical protein 0.011
ADH4 Adh4p 0.011
NIF3 Nif3p 0.011
YIR035C hypothetical protein 0.011
YBL055C hypothetical protein 0.011
IPT1 Ipt1p 0.011
COT1 Cot1p 0.011
CYS3 Cys3p 0.011
APT2 Apt2p 0.011
CHO2 Cho2p 0.011
PTK1 Ptk1p 0.011
YFR006W hypothetical protein 0.011
GLN1 Gln1p 0.011
YGR017W hypothetical protein 0.011
SRD1 Srd1p 0.011
BRN1 Brn1p 0.011
ARP10 Arp10p 0.010
MRS1 Mrs1p 0.010
PBP4 Pbp4p 0.010
SSP120 Ssp120p 0.010
MCX1 Mcx1p 0.010
YLR162W hypothetical protein 0.010
ARG8 Arg8p 0.010
YLR057W hypothetical protein 0.010
YOL098C hypothetical protein 0.010
PRS2 Prs2p 0.010
FCY21 Fcy21p 0.010
TRP1 Trp1p 0.010
YKL023W hypothetical protein 0.010
YLR264C-A hypothetical protein 0.010
OYE2 Oye2p 0.010
PUS6 Pus6p 0.010
ECT1 Ect1p 0.010
YOL038C-A hypothetical protein 0.010
MET8 Met8p 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
sams-3 Protein SAMS-3 0.168
C53C9.2 Protein C53C9.2 0.042
T22D1.3 Protein T22D1.3 0.031
F55G1.5 Protein F55G1.5 0.029
F22B5.10 Protein F22B5.10 0.024
tram-1 Protein TRAM-1 0.023
nduf-2.2 Protein NDUF-2.2 0.022
sams-4 Protein SAMS-4 0.020
F42G4.2 Protein F42G4.2 0.020
mel-32 Protein MEL-32 0.020
acs-5 Protein ACS-5 0.018
asb-1 Protein ASB-1 0.017
ssp-9 Protein SSP-9 0.014
CELE_C01G12.3 Protein C01G12.3 0.014
CELE_F36A4.1 Protein F36A4.1 0.013
aagr-4 Protein AAGR-4 0.013
iglr-2 Protein IGLR-2 0.013
CELE_Y39G10AR.8 Protein Y39G10AR.8 0.012
crm-1 Protein CRM-1 0.012
arf-3 Protein ARF-3 0.012
CELE_Y50E8A.2 Protein Y50E8A.2 0.012
mthf-1 Protein MTHF-1 0.012
apg-1 Protein APG-1 0.012
cmd-1 Protein CMD-1 0.011
trap-2 Protein TRAP-2 0.011
CELE_Y57G11C.15 Protein Y57G11C.15 0.011
ZK930.7 Protein ZK930.7 0.011
CELE_Y75B8A.24 Protein Y75B8A.24 0.011
Y48A6B.3 Protein Y48A6B.3 0.011
mtrr-1 Protein MTRR-1 0.011
ncbp-2 Protein NCBP-2 0.011
CELE_F46F2.3 Protein F46F2.3 0.010
ksr-1 Protein KSR-1 0.010
CELE_F36D1.4 Protein F36D1.4 0.010
tag-267 Protein TAG-267 0.010
ahcy-1 Protein AHCY-1 0.010
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
GCLC glutamate-cysteine ligase, catalytic subunit 0.662
GCLM glutamate-cysteine ligase, modifier subunit 0.589
TFG TRK-fused gene 0.446
SOD1 superoxide dismutase 1, soluble 0.351
PRDX1 peroxiredoxin 1 0.197
NECAP2 NECAP endocytosis associated 2 0.162
PLSCR4 phospholipid scramblase 4 0.137
DLG2 discs, large homolog 2 (Drosophila) 0.125
SP100 SP100 nuclear antigen 0.075
CALCA calcitonin-related polypeptide alpha 0.061
PRDX2 peroxiredoxin 2 0.049
METRN meteorin, glial cell differentiation regulator 0.046
STT3A STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) 0.037
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 0.035
CRY1 cryptochrome 1 (photolyase-like) 0.029
TXN thioredoxin 0.028
MBNL1 muscleblind-like (Drosophila) 0.028
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 0.027
DAD1 defender against cell death 1 0.026
ACLY ATP citrate lyase 0.026
MAPK3 mitogen-activated protein kinase 3 0.025
LASP1 LIM and SH3 protein 1 0.025
NONO non-POU domain containing, octamer-binding 0.024
MAGEA11 melanoma antigen family A, 11 0.024
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.023
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.023
NDUFA4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa 0.023
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.021
NME4 non-metastatic cells 4, protein expressed in 0.021
PRDX4 peroxiredoxin 4 0.020
AK2 adenylate kinase 2 0.020
OSBPL8 oxysterol binding protein-like 8 0.019
NTN4 netrin 4 0.019
OCLN occludin 0.019
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.018
NAMPT nicotinamide phosphoribosyltransferase 0.018
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.017
RHOXF2 Rhox homeobox family, member 2 0.017
PRDX5 peroxiredoxin 5 0.017
TCTN3 tectonic family member 3 0.017
IFI16 interferon, gamma-inducible protein 16 0.017
ERBB2IP erbb2 interacting protein 0.016
DLG1 discs, large homolog 1 (Drosophila) 0.016
NEU4 sialidase 4 0.016
FAM103A1 family with sequence similarity 103, member A1 0.015
SRSF5 serine/arginine-rich splicing factor 5 0.015
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.015
ADCY7 adenylate cyclase 7 0.014
CDK17 cyclin-dependent kinase 17 0.014
RCC2 regulator of chromosome condensation 2 0.014
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.013
SOD2 superoxide dismutase 2, mitochondrial 0.013
BANP BTG3 associated nuclear protein 0.013
SDCBP syndecan binding protein (syntenin) 0.013
ADAM17 ADAM metallopeptidase domain 17 0.013
TMED5 transmembrane emp24 protein transport domain containing 5 0.013
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.012
ARL15 ADP-ribosylation factor-like 15 0.012
C10orf10 chromosome 10 open reading frame 10 0.012
TNNI2 troponin I type 2 (skeletal, fast) 0.011
PRDX6 peroxiredoxin 6 0.011
HPD 4-hydroxyphenylpyruvate dioxygenase 0.011
KIAA0090 KIAA0090 0.011
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.011
MAPK7 mitogen-activated protein kinase 7 0.010
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.010
PIR pirin (iron-binding nuclear protein) 0.010
ZFAND2B zinc finger, AN1-type domain 2B 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Gclm glutamate-cysteine ligase, modifier subunit 0.950
Gclc glutamate-cysteine ligase, catalytic subunit 0.946
Ldb3 LIM domain binding 3 0.171
Tcap titin-cap 0.149
Hrc histidine rich calcium binding protein 0.117
Sgca sarcoglycan, alpha (dystrophin-associated glycoprotein) 0.094
Gp9 glycoprotein 9 (platelet) 0.094
Casq1 calsequestrin 1 0.076
Pgam2 phosphoglycerate mutase 2 0.074
Actn2 actinin alpha 2 0.064
Alox15 arachidonate 15-lipoxygenase 0.054
Rab25 RAB25, member RAS oncogene family 0.051
Cox8b cytochrome c oxidase, subunit VIIIb 0.049
Apobec2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2 0.049
Tmem40 transmembrane protein 40 0.049
Camp cathelicidin antimicrobial peptide 0.049
Mybph myosin binding protein H 0.042
Qdpr quinoid dihydropteridine reductase 0.039
Gcsh glycine cleavage system protein H (aminomethyl carrier) 0.035
Abp1 amiloride binding protein 1 (amine oxidase, copper-containing) 0.035
Myl3 myosin, light polypeptide 3 0.034
Fbp2 fructose bisphosphatase 2 0.034
Pgls 6-phosphogluconolactonase 0.032
Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.032
Plin4 perilipin 4 0.031
Krt15 keratin 15 0.031
Fbp1 fructose bisphosphatase 1 0.031
Rexo2 REX2, RNA exonuclease 2 homolog (S. cerevisiae) 0.030
Zfp385a zinc finger protein 385A 0.030
Thoc1 THO complex 1 0.029
Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) 0.029
Adig adipogenin 0.029
Art1 ADP-ribosyltransferase 1 0.028
Xirp1 xin actin-binding repeat containing 1 0.028
Myom2 myomesin 2 0.028
Cox6a2 cytochrome c oxidase, subunit VI a, polypeptide 2 0.028
Mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase 0.027
Galnt6 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 0.027
Retn resistin 0.027
Padi1 peptidyl arginine deiminase, type I 0.026
Tnni2 troponin I, skeletal, fast 2 0.026
Ltf lactotransferrin 0.025
Kcna7 potassium voltage-gated channel, shaker-related subfamily, member 7 0.025
Pcx pyruvate carboxylase 0.024
Itgb3 integrin beta 3 0.024
Tnnt3 troponin T3, skeletal, fast 0.023
Fcgbp Fc fragment of IgG binding protein 0.023
Reep6 receptor accessory protein 6 0.022
Crat carnitine acetyltransferase 0.021
Sult2b1 sulfotransferase family, cytosolic, 2B, member 1 0.020
Sit1 suppression inducing transmembrane adaptor 1 0.020
Nrap nebulin-related anchoring protein 0.020
Dctpp1 dCTP pyrophosphatase 1 0.020
D17H6S56E-3 DNA segment, Chr 17, human D6S56E 3 0.020
S100a3 S100 calcium binding protein A3 0.019
Fbxo9 f-box protein 9 0.019
Mrps25 mitochondrial ribosomal protein S25 0.019
Dus1l dihydrouridine synthase 1-like (S. cerevisiae) 0.019
Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.019
Pnpo pyridoxine 5'-phosphate oxidase 0.019
Gsr glutathione reductase 0.018
Fam83g family with sequence similarity 83, member G 0.018
Dmpk dystrophia myotonica-protein kinase 0.018
Ggt1 gamma-glutamyltransferase 1 0.017
Tmem93 transmembrane protein 93 0.017
Alpk3 alpha-kinase 3 0.017
Myh2 myosin, heavy polypeptide 2, skeletal muscle, adult 0.017
Pebp1 phosphatidylethanolamine binding protein 1 0.017
Fam83f family with sequence similarity 83, member F 0.017
Slc25a45 solute carrier family 25, member 45 0.017
Gyk glycerol kinase 0.017
Itgb1bp2 integrin beta 1 binding protein 2 0.016
Clic3 chloride intracellular channel 3 0.016
Ei24 etoposide induced 2.4 mRNA 0.016
Rif1 Rap1 interacting factor 1 homolog (yeast) 0.016
Mdfi MyoD family inhibitor 0.016
Star steroidogenic acute regulatory protein 0.015
Zfp335 zinc finger protein 335 0.015
Ltc4s leukotriene C4 synthase 0.015
Tuba8 tubulin, alpha 8 0.014
Pnliprp2 pancreatic lipase-related protein 2 0.014
Gch1 GTP cyclohydrolase 1 0.014
Alad aminolevulinate, delta-, dehydratase 0.014
Mtch1 mitochondrial carrier homolog 1 (C. elegans) 0.014
Hspa8 heat shock protein 8 0.014
Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A 0.014
Glo1 glyoxalase 1 0.013
Lgals7 lectin, galactose binding, soluble 7 0.013
Gpr132 G protein-coupled receptor 132 0.013
Phkg1 phosphorylase kinase gamma 1 0.013
Col11a2 collagen, type XI, alpha 2 0.013
Ppara peroxisome proliferator activated receptor alpha 0.013
Ccl11 chemokine (C-C motif) ligand 11 0.013
Tbxa2r thromboxane A2 receptor 0.013
Mrpl28 mitochondrial ribosomal protein L28 0.013
Actn3 actinin alpha 3 0.013
Crct1 cysteine-rich C-terminal 1 0.013
Stc2 stanniocalcin 2 0.013
Ttn titin 0.012
Mb myoglobin 0.012
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Rattus norvegicus
Name Description Probability Func Analog Organism
Txnrd1 thioredoxin reductase 1 0.243
Ubqln1 ubiquilin 1 0.196
Gclc glutamate-cysteine ligase, catalytic subunit 0.188
Shmt1 serine hydroxymethyltransferase 1 (soluble) 0.174
Pgam2 phosphoglycerate mutase 2 (muscle) 0.152
Gclm glutamate cysteine ligase, modifier subunit 0.123
Tst thiosulfate sulfurtransferase 0.090
Alad aminolevulinate, delta-, dehydratase 0.081
Slc25a10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 0.067
Tfrc transferrin receptor 0.065
Ahcy adenosylhomocysteinase 0.060
Pecr peroxisomal trans-2-enoyl-CoA reductase 0.058
Pctp phosphatidylcholine transfer protein 0.057
Csnk2b casein kinase 2, beta polypeptide 0.057
Dph1 DPH1 homolog (S. cerevisiae) 0.056
Ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 0.054
Sh3bgr SH3 domain binding glutamic acid-rich protein 0.054
Me1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.053
Hrsp12 heat-responsive protein 12 0.052
Acy1 aminoacylase 1 0.051
Tff3 trefoil factor 3, intestinal 0.051
Nqo1 NAD(P)H dehydrogenase, quinone 1 0.048
Pygm phosphorylase, glycogen, muscle 0.046
Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 0.045
Pygb phosphorylase, glycogen; brain 0.043
Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 0.043
Sf3b3 splicing factor 3b, subunit 3 0.042
Mtpn myotrophin 0.040
Mgst3 microsomal glutathione S-transferase 3 0.040
Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 0.039
Krt34 keratin 34 0.039
Ugdh UDP-glucose dehydrogenase 0.039
LOC100363662 6-phosphogluconate dehydrogenase, decarboxylating-like 0.039
Gsta5 glutathione S-transferase Yc2 subunit 0.038
Coq10b coenzyme Q10 homolog B (S. cerevisiae) 0.037
Aldh4a1 aldehyde dehydrogenase 4 family, member A1 0.036
Tecr trans-2,3-enoyl-CoA reductase 0.035
RGD1306682 similar to RIKEN cDNA 1810046J19 0.035
Arl2 ADP-ribosylation factor-like 2 0.035
Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 0.035
Atad3a ATPase family, AAA domain containing 3A 0.034
Rnps1 ribonucleic acid binding protein S1 0.034
Hnf4a hepatocyte nuclear factor 4, alpha 0.034
Arl5a ADP-ribosylation factor-like 5A 0.034
Gss glutathione synthetase 0.032
Pigl phosphatidylinositol glycan anchor biosynthesis, class L 0.032
Mylpf myosin light chain, phosphorylatable, fast skeletal muscle 0.032
Des desmin 0.031
Srd5a1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 0.031
Mapk6 mitogen-activated protein kinase 6 0.029
Pacs1 phosphofurin acidic cluster sorting protein 1 0.029
Ung uracil-DNA glycosylase 0.029
Ahr aryl hydrocarbon receptor 0.029
Akr7a3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.029
Vtcn1 V-set domain containing T cell activation inhibitor 1 0.028
Fen1 flap structure-specific endonuclease 1 0.028
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.027
Akr7a2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.027
Rpa2 replication protein A2 0.027
Sult5a1 sulfotransferase family 5A, member 1 0.026
Odc1 ornithine decarboxylase 1 0.026
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.026
Qprt quinolinate phosphoribosyltransferase 0.025
Reep6 receptor accessory protein 6 0.025
Ube4a ubiquitination factor E4A (UFD2 homolog, yeast) 0.025
Rhd Rh blood group, D antigen 0.025
Mybbp1a MYB binding protein (P160) 1a 0.025
Aldh7a1 aldehyde dehydrogenase 7 family, member A1 0.024
Pgrmc1 progesterone receptor membrane component 1 0.024
Nmu neuromedin U 0.024
Hn1l hematological and neurological expressed 1-like 0.024
Eif4h eukaryotic translation initiation factor 4H 0.023
Ccl28 chemokine (C-C motif) ligand 28 0.023
Mef2d myocyte enhancer factor 2D 0.022
Polr1b polymerase (RNA) I polypeptide B 0.022
Hmbs hydroxymethylbilane synthase 0.022
Sfrs3 splicing factor, arginine/serine-rich 3 0.022
Myl1 myosin, light chain 1 0.022
Rnf5 ring finger protein 5 0.022
Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 0.022
Pafah1b2 platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 0.022
Atp2a3 ATPase, Ca++ transporting, ubiquitous 0.021
Polr1e polymerase (RNA) I polypeptide E 0.021
Cdcp1 CUB domain containing protein 1 0.021
Pde5a phosphodiesterase 5A, cGMP-specific 0.021
Fxyd4 FXYD domain-containing ion transport regulator 4 0.021
Aldh18a1 aldehyde dehydrogenase 18 family, member A1 0.021
Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) 0.021
Exosc5 exosome component 5 0.020
Phka1 phosphorylase kinase, alpha 1 0.020
Cat catalase 0.020
Dhrs7c dehydrogenase/reductase (SDR family) member 7C 0.020
Shmt2 serine hydroxymethyltransferase 2 (mitochondrial) 0.020
Qdpr quinoid dihydropteridine reductase 0.019
Gja5 gap junction protein, alpha 5 0.019
Josd2 Josephin domain containing 2 0.019
Stub1 STIP1 homology and U-Box containing protein 1 0.019
Asl argininosuccinate lyase 0.019
Aqp9 aquaporin 9 0.019
Stmn4 stathmin-like 4 0.019