The network for 'actin filament organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

actin filament organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ABP1 Abp1p 0.982
ACT1 Act1p 0.981
RHO1 Rho1p 0.981
SLA2 Sla2p 0.981
LAS17 Las17p 0.977
BEM3 Bem3p 0.975
CAP2 Cap2p 0.973
SRV2 Srv2p 0.965
MYO5 Myo5p 0.915
ARP3 Arp3p 0.891
ARC15 Arc15p 0.890
CDC42 Cdc42p 0.889
CDC24 Cdc24p 0.875
BBC1 Bbc1p 0.868
ARC35 Arc35p 0.860
SLA1 Sla1p 0.832
LSB1 Lsb1p 0.823
YSC84 Ysc84p 0.821
ARP2 Arp2p 0.808
RVS167 Rvs167p 0.801
PRK1 Prk1p 0.729
PAN1 Pan1p 0.725
SAC6 Sac6p 0.706
RDI1 Rdi1p 0.699
TPM1 Tpm1p 0.686
ARC19 Arc19p 0.683
ENT2 Ent2p 0.641
PFY1 Pfy1p 0.606
ARC18 Arc18p 0.602
BOI1 Boi1p 0.555
ARC40 Arc40p 0.533
MKK1 Mkk1p 0.495
CYK3 Cyk3p 0.456
BEM4 Bem4p 0.450
CMD1 Cmd1p 0.443
APP1 App1p 0.407
SCP1 Scp1p 0.385
CAP1 Cap1p 0.382
PKC1 Pkc1p 0.380
PIN3 Pin3p 0.378
BSP1 Bsp1p 0.347
SPA2 Spa2p 0.325
RGD1 Rgd1p 0.319
TSC11 Tsc11p 0.317
CDC55 Cdc55p 0.277
TCO89 Tco89p 0.269
AIP1 Aip1p 0.251
MLC1 Mlc1p 0.239
END3 End3p 0.223
CLA4 Cla4p 0.220
BZZ1 Bzz1p 0.214
AQY2 Aqy2p 0.204
PPH21 Pph21p 0.196
INP52 Inp52p 0.193
VRP1 Vrp1p 0.181
COF1 Cof1p 0.160
ARK1 Ark1p 0.157
BNI1 Bni1p 0.151
AVO2 Avo2p 0.146
AIM21 Aim21p 0.143
AFI1 Afi1p 0.142
FYV8 Fyv8p 0.137
AKL1 Akl1p 0.137
STE5 Ste5p 0.136
MYO2 Myo2p 0.133
FAR1 Far1p 0.132
STE11 Ste11p 0.128
BEM2 Bem2p 0.123
STE12 Ste12p 0.117
CDC12 Cdc12p 0.116
OCA1 Oca1p 0.105
BUD14 Bud14p 0.098
SAC7 Sac7p 0.096
ROM2 Rom2p 0.096
KOG1 Kog1p 0.095
MSB4 Msb4p 0.093
ENT1 Ent1p 0.090
PEF1 Pef1p 0.088
AIM3 Aim3p 0.086
PST2 Pst2p 0.085
BUD6 Bud6p 0.084
INN1 Inn1p 0.082
PTC1 Ptc1p 0.081
SOG2 Sog2p 0.079
MYO4 Myo4p 0.078
TAO3 Tao3p 0.076
SKM1 Skm1p 0.076
LEM3 Lem3p 0.075
SSO2 Sso2p 0.075
YPR148C hypothetical protein 0.074
LSB6 Lsb6p 0.073
AIM6 Aim6p 0.072
FIR1 Fir1p 0.071
YCP4 Ycp4p 0.068
TOR2 Tor2p 0.068
MOB1 Mob1p 0.068
TWF1 Twf1p 0.067
DIG1 Dig1p 0.067
MYO1 Myo1p 0.066
ACK1 Ack1p 0.065
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
M02D8.1 Protein M02D8.1 0.201
unc-15 Protein UNC-15 0.121
unc-52 Protein UNC-52 0.107
let-60 Protein LET-60 0.095
ajm-1 Protein AJM-1 0.088
inx-13 Protein INX-13 0.087
mig-2 Protein MIG-2 0.085
mpk-1 Protein MPK-1 0.083
sorb-1 Protein SORB-1 0.082
T25F10.6 Protein T25F10.6 0.063
atn-1 Protein ATN-1 0.063
C11E4.6 Protein C11E4.6 0.056
myo-3 Protein MYO-3 0.055
T21B6.3 Protein T21B6.3 0.054
pkn-1 Protein PKN-1 0.046
let-2 Protein LET-2 0.045
unc-45 Protein UNC-45 0.045
unc-112 Protein UNC-112 0.044
unc-27 Protein UNC-27 0.042
ost-1 Protein OST-1 0.042
cdc-42 Protein CDC-42 0.040
C27H2.2 Protein C27H2.2 0.037
sem-5 Protein SEM-5 0.037
tag-163 Protein TAG-163 0.037
T03G6.3 Protein T03G6.3 0.037
CELE_C55A6.12 Protein C55A6.12 0.036
emb-9 Protein EMB-9 0.035
unc-68 Protein UNC-68 0.034
CELE_Y45F10B.13 Protein Y45F10B.13 0.034
ina-1 Protein INA-1 0.032
tni-1 Protein TNI-1 0.031
C29F5.1 Protein C29F5.1 0.030
unc-116 Protein UNC-116 0.030
unc-60 Protein UNC-60 0.030
dnj-27 Protein DNJ-27 0.029
ifb-1 Protein IFB-1 0.029
deb-1 Protein DEB-1 0.028
pat-12 Protein PAT-12 0.028
vab-10 Protein VAB-10 0.026
CELE_D1025.1 Protein D1025.1 0.025
C43H6.4 Protein C43H6.4 0.025
goa-1 Protein GOA-1 0.025
mlc-2 Protein MLC-2 0.025
act-4 Protein ACT-4 0.024
klc-2 Protein KLC-2 0.024
spr-5 Protein SPR-5 0.024
csn-5 Protein CSN-5 0.023
CELE_W05H12.1 Protein W05H12.1 0.023
cpn-1 Protein CPN-1 0.021
chc-1 Protein CHC-1 0.021
cpn-3 Protein CPN-3 0.021
pfn-3 Protein PFN-3 0.021
egl-30 Protein EGL-30 0.021
C53C9.2 Protein C53C9.2 0.021
acs-13 Protein ACS-13 0.020
tbb-4 Protein TBB-4 0.020
kgb-1 Protein KGB-1 0.020
unc-16 Protein UNC-16 0.019
csnk-1 Protein CSNK-1 0.019
zyx-1 Protein ZYX-1 0.019
jmjd-3.1 Protein JMJD-3.1 0.019
csq-1 Protein CSQ-1 0.019
T19D12.5 Protein T19D12.5 0.019
tni-3 Protein TNI-3 0.018
tnt-2 Protein TNT-2 0.018
unc-43 Protein UNC-43 0.018
ccpp-1 Protein CCPP-1 0.018
bam-2 Protein BAM-2 0.018
mig-6 Protein MIG-6 0.017
sel-8 Protein SEL-8 0.017
unc-53 Protein UNC-53 0.017
mig-5 Protein MIG-5 0.017
ifg-1 Protein IFG-1 0.017
unc-32 Protein UNC-32 0.017
myo-2 Protein MYO-2 0.017
hmp-1 Protein HMP-1 0.017
dep-1 Protein DEP-1 0.017
paa-1 Protein PAA-1 0.016
CELE_C08H9.2 Protein C08H9.2 0.016
F44B9.2 Protein F44B9.2 0.016
CELE_B0513.5 Protein B0513.5 0.016
rsbp-1 Protein RSBP-1 0.016
T26C12.1 Protein T26C12.1 0.016
F43D9.1 Protein F43D9.1 0.016
nrde-3 Protein NRDE-3 0.016
M70.1 Protein M70.1 0.016
cst-2 Protein CST-2 0.016
ced-10 Protein CED-10 0.016
lmn-1 Protein LMN-1 0.016
T13H5.6 Protein T13H5.6 0.016
ifa-1 Protein IFA-1 0.016
par-5 Protein PAR-5 0.016
rsy-1 Protein RSY-1 0.016
mec-2 Protein MEC-2 0.015
arx-5 Protein ARX-5 0.015
CELE_Y47G6A.18 Protein Y47G6A.18 0.015
CELE_F13E9.11 Protein F13E9.11 0.015
erm-1 Protein ERM-1 0.015
tag-296 Protein TAG-296 0.015
C18B2.5 Protein C18B2.5 0.015
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
kdrl kinase insert domain receptor like 0.888
myhz1.1 myosin, heavy polypeptide 1.1, skeletal muscle 0.795
smyhc2 slow myosin heavy chain 2 0.432
cotl1 coactosin-like 1 (Dictyostelium) 0.406
itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.397
bactin1 bactin1 0.390
s100a10b S100 calcium binding protein A10b 0.361
vegfc vascular endothelial growth factor c 0.360
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.356
cyt1 type I cytokeratin, enveloping layer 0.229
six1b sine oculis homeobox homolog 1b 0.213
scinla scinderin like a 0.188
msna moesin a 0.180
pacsin3 protein kinase C and casein kinase substrate in neurons 3 0.174
tnni1al troponin I, skeletal, slow like 0.169
sox4a SRY-box containing gene 4a 0.166
si:ch73-60e21.1 si:ch73-60e21.1 0.156
pdlim1 PDZ and LIM domain 1 (elfin) 0.124
fras1 Fraser syndrome 1 0.121
zgc:100942 zgc:100942 0.119
s1pr2 sphingosine-1-phosphate receptor 2 0.109
frem3 Fras1 related extracellular matrix 3 0.108
zgc:153867 zgc:153867 0.107
unc45b unc-45 homolog B (C. elegans) 0.105
ptmab prothymosin, alpha b 0.104
calm3b calmodulin 3b (phosphorylase kinase, delta) 0.103
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.103
ilk integrin linked kinase 0.102
tnnt3a troponin T3a, skeletal, fast 0.094
pdlim5 PDZ and LIM domain 5 0.091
irf6 interferon regulatory factor 6 0.089
tnnc1b troponin C type 1b (slow) 0.088
tpm3 tropomyosin 3 0.087
gng3 guanine nucleotide binding protein (G protein), gamma 3 0.086
tpm4 tropomyosin 4 0.085
tnni2a.4 troponin I, skeletal, fast 2a.4 0.085
tnnt1 troponin T1, skeletal, slow 0.084
flncb filamin C, gamma b (actin binding protein 280) 0.079
cnn2 calponin 2 0.076
gna11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.076
pdlim2 PDZ and LIM domain 2 (mystique) 0.075
itgb1b integrin, beta 1b 0.074
hspb8 heat shock protein, alpha-crystallin-related, b8 0.074
tie1 endothelium-specific receptor tyrosine kinase 1 0.068
LOC100331639 hypothetical protein LOC100331639 0.066
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.066
gna13a guanine nucleotide binding protein (G protein), alpha 13a 0.065
gapdh glyceraldehyde-3-phosphate dehydrogenase 0.063
myl9l myosin, light polypeptide 9, like 0.063
flot2a flotillin 2a 0.063
zbtb4 zinc finger and BTB domain containing 4 0.063
LOC795916 mucolipin-1-like 0.062
ptger2a prostaglandin E receptor 2a (subtype EP2) 0.061
smc1al structural maintenance of chromosomes 1A, like 0.061
arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.058
itgb3b integrin beta 3b 0.058
hspg2 heparan sulfate proteoglycan 2 0.056
fabp7a fatty acid binding protein 7, brain, a 0.056
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.054
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.053
smyhc1l slow myosin heavy chain 1, like 0.053
ryr3 ryanodine receptor 3 0.052
vangl2 vang-like 2 (van gogh, Drosophila) 0.051
smyd1b SET and MYND domain containing 1b 0.050
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.050
pikfyve phosphoinositide kinase, FYVE finger containing 0.049
pak1 p21/Cdc42/Rac1-activated kinase 1 0.049
fgfr1a fibroblast growth factor receptor 1a 0.048
myf6 myogenic factor 6 0.047
xirp2a xin actin-binding repeat containing 2a 0.047
nphs2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.047
casp3a caspase 3, apoptosis-related cysteine protease a 0.046
gfi1.1 growth factor independent 1.1 0.046
itgb1a integrin, beta 1a 0.046
me2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.046
appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.045
gng12a guanine nucleotide binding protein (G protein), gamma 12a 0.045
acta1a actin, alpha 1a, skeletal muscle 0.045
celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 and cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) 0.045
esrra estrogen-related receptor alpha 0.044
wnt10a wingless-type MMTV integration site family, member 10a 0.044
ptp4a3 protein tyrosine phosphatase type IVA, member 3 0.043
csrp1a cysteine and glycine-rich protein 1a 0.043
ckma creatine kinase, muscle a 0.042
diaph2 diaphanous homolog 2 (Drosophila) 0.041
sh3gl1b SH3-domain GRB2-like 1b 0.041
xirp1 xin actin-binding repeat containing 1 0.040
gpc4 glypican 4 0.039
tcf7l1a transcription factor 7-like 1a (T-cell specific, HMG-box) 0.039
itga2b integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B) 0.038
tnnt3b troponin T3b, skeletal, fast 0.038
igfbp3 insulin-like growth factor binding protein 3 0.037
smyhc1 slow myosin heavy chain 1 0.037
alcamb activated leukocyte cell adhesion molecule b 0.036
snx12 sorting nexin 12 0.036
si:dkey-204a24.2 si:dkey-204a24.2 0.036
ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a 0.035
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.035
sox2 SRY-box containing gene 2 0.035
ptmaa prothymosin, alpha a 0.035
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
rok Rho-kinase 0.997
chic chickadee 0.996
Rala Ras-related protein 0.987
flw flapwing 0.981
Arp66B Actin-related protein 66B 0.973
kuz kuzbanian 0.940
dsh dishevelled 0.931
WASp CG1520 gene product from transcript CG1520-RA 0.928
bsk basket 0.923
sn singed 0.921
mbc myoblast city 0.885
sls sallimus 0.880
fu fused 0.876
mys myospheroid 0.854
Rac2 CG8556 gene product from transcript CG8556-RA 0.852
katanin-60 katanin 60 0.848
hep hemipterous 0.836
cpb capping protein beta 0.831
Arp14D Actin-related protein 14D 0.793
fz frizzled 0.789
Cip4 CG15015 gene product from transcript CG15015-RA 0.785
Lis-1 Lissencephaly-1 0.785
zip zipper 0.779
Fmr1 CG6203 gene product from transcript CG6203-RC 0.760
S6k RPS6-p70-protein kinase 0.754
par-1 CG8201 gene product from transcript CG8201-RA 0.752
m miniature 0.726
Hem HEM-protein 0.711
Arc-p34 CG10954 gene product from transcript CG10954-RA 0.695
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.690
msn misshapen 0.688
Cdc42 CG12530 gene product from transcript CG12530-RA 0.681
bif bifocal 0.680
ovo CG6824 gene product from transcript CG6824-RE 0.678
Sra-1 specifically Rac1-associated protein 1 0.677
bun bunched 0.675
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.671
G-ialpha65A G protein alphai subunit 65A 0.666
Src64B Src oncogene at 64B 0.656
rst roughest 0.651
hts hu li tai shao 0.631
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.630
baz bazooka 0.612
ck crinkled 0.582
wts warts 0.581
cindr CIN85 and CD2AP orthologue 0.578
Pink1 PTEN-induced putative kinase 1 0.570
nyo nyobe 0.551
Pak PAK-kinase 0.545
mbt mushroom bodies tiny 0.542
numb CG3779 gene product from transcript CG3779-RB 0.528
ena enabled 0.527
Mhc Myosin heavy chain 0.527
trio CG18214 gene product from transcript CG18214-RA 0.497
Caps Calcium activated protein for secretion 0.497
jar jaguar 0.484
Rac1 CG2248 gene product from transcript CG2248-RA 0.473
egh egghead 0.468
neur neuralized 0.467
wupA wings up A 0.463
if inflated 0.453
Rab23 CG2108 gene product from transcript CG2108-RA 0.445
Pax Paxillin 0.432
chb chromosome bows 0.424
Arf51F ADP ribosylation factor 51F 0.423
spir spire 0.421
rl rolled 0.410
CG3563 CG3563 gene product from transcript CG3563-RA 0.408
Dcr-2 Dicer-2 0.406
rictor rapamycin-insensitive companion of Tor 0.366
nos nanos 0.362
sgg shaggy 0.358
Akt1 CG4006 gene product from transcript CG4006-RA 0.356
Jra Jun-related antigen 0.344
kel kelch 0.344
Dad Daughters against dpp 0.342
alpha-Adaptin CG4260 gene product from transcript CG4260-RA 0.341
p130CAS CG1212 gene product from transcript CG1212-RA 0.341
key kenny 0.339
Khc Kinesin heavy chain 0.336
up upheld 0.333
Pak3 CG14895 gene product from transcript CG14895-RA 0.332
Vrp1 Verprolin 1 0.329
Pvr PDGF- and VEGF-receptor related 0.326
nmo nemo 0.325
sd scalloped 0.316
wun wunen 0.294
CG13962 CG13962 gene product from transcript CG13962-RA 0.290
twf twinfilin 0.290
Act57B Actin 57B 0.285
cher cheerio 0.285
Act88F Actin 88F 0.279
bchs blue cheese 0.274
Mp20 Muscle protein 20 0.273
mi minus 0.268
Atg1 Autophagy-specific gene 1 0.265
Mrtf Myocardin-related transcription factor 0.264
Mical Molecule interacting with CasL 0.264
Mlc2 Myosin light chain 2 0.263
Act5C Actin 5C 0.262
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
GRB2 growth factor receptor-bound protein 2 1.000
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
EGFR epidermal growth factor receptor 1.000
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 1.000
FLNA filamin A, alpha 1.000
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 1.000
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
FYN FYN oncogene related to SRC, FGR, YES 1.000
ZYX zyxin 1.000
SH3KBP1 SH3-domain kinase binding protein 1 1.000
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.000
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.000
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
IQGAP1 IQ motif containing GTPase activating protein 1 1.000
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.999
ACTB actin, beta 0.999
MYH9 myosin, heavy chain 9, non-muscle 0.999
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.999
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.998
PFN1 profilin 1 0.996
FN1 fibronectin 1 0.996
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.996
RHOA ras homolog gene family, member A 0.996
GAS7 growth arrest-specific 7 0.989
CFL1 cofilin 1 (non-muscle) 0.989
ACTG1 actin, gamma 1 0.989
DNM2 dynamin 2 0.989
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.987
HCK hemopoietic cell kinase 0.983
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.974
SOS1 son of sevenless homolog 1 (Drosophila) 0.973
BCAR1 breast cancer anti-estrogen resistance 1 0.973
ABI1 abl-interactor 1 0.971
TRIM63 tripartite motif containing 63 0.966
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.961
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.960
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.955
LMNA lamin A/C 0.955
VCL vinculin 0.954
TPM4 tropomyosin 4 0.952
S100A11 S100 calcium binding protein A11 0.948
VAV1 vav 1 guanine nucleotide exchange factor 0.945
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.944
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.941
BAIAP2 BAI1-associated protein 2 0.939
ACTN1 actinin, alpha 1 0.938
WASL Wiskott-Aldrich syndrome-like 0.935
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.931
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 0.930
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.922
SPTAN1 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 0.917
SYK spleen tyrosine kinase 0.912
PLCG1 phospholipase C, gamma 1 0.912
PLEC plectin 0.897
SH3BGRL3 SH3 domain binding glutamic acid-rich protein like 3 0.896
MSN moesin 0.891
TPM1 tropomyosin 1 (alpha) 0.884
SH3BP2 SH3-domain binding protein 2 0.867
S100A6 S100 calcium binding protein A6 0.857
ESR1 estrogen receptor 1 0.855
JAG1 jagged 1 0.854
GRB7 growth factor receptor-bound protein 7 0.853
PDCD6IP programmed cell death 6 interacting protein 0.852
ATXN1 ataxin 1 0.848
SFN stratifin 0.845
ACTN4 actinin, alpha 4 0.840
TTN titin 0.838
PTK2 PTK2 protein tyrosine kinase 2 0.837
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 0.828
CLTC clathrin, heavy chain (Hc) 0.810
ILK integrin-linked kinase 0.809
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.790
CORO1C coronin, actin binding protein, 1C 0.779
HIPK3 homeodomain interacting protein kinase 3 0.768
SORBS3 sorbin and SH3 domain containing 3 0.767
ARRB2 arrestin, beta 2 0.767
PLXNB1 plexin B1 0.763
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.748
CNN2 calponin 2 0.746
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.742
LRRK2 leucine-rich repeat kinase 2 0.731
VASP vasodilator-stimulated phosphoprotein 0.724
ARHGAP1 Rho GTPase activating protein 1 0.719
TRIP10 thyroid hormone receptor interactor 10 0.714
CAPNS1 calpain, small subunit 1 0.706
ITSN1 intersectin 1 (SH3 domain protein) 0.686
CAPZB capping protein (actin filament) muscle Z-line, beta 0.685
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.685
TJP1 tight junction protein 1 (zona occludens 1) 0.679
COTL1 coactosin-like 1 (Dictyostelium) 0.664
WDR1 WD repeat domain 1 0.661
INPPL1 inositol polyphosphate phosphatase-like 1 0.657
S100B S100 calcium binding protein B 0.657
NOTCH3 notch 3 0.648
PALLD palladin, cytoskeletal associated protein 0.647
WIPF1 WAS/WASL interacting protein family, member 1 0.643
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.638
SPRR2A small proline-rich protein 2A 0.636
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.630
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.999
Vasp vasodilator-stimulated phosphoprotein 0.998
Rac1 RAS-related C3 botulinum substrate 1 0.998
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.995
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.993
Src Rous sarcoma oncogene 0.992
Wdr1 WD repeat domain 1 0.991
Efnb2 ephrin B2 0.986
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.986
Abi1 abl-interactor 1 0.964
Ush1g Usher syndrome 1G homolog (human) 0.961
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.958
Capzb capping protein (actin filament) muscle Z-line, beta 0.951
Tagln transgelin 0.950
Cttn cortactin 0.949
Actn1 actinin, alpha 1 0.942
Itga3 integrin alpha 3 0.935
Ctnnb1 catenin (cadherin associated protein), beta 1 0.933
Wipf1 WAS/WASL interacting protein family, member 1 0.930
Msn moesin 0.929
Braf Braf transforming gene 0.924
Actg1 actin, gamma, cytoplasmic 1 0.904
Prkce protein kinase C, epsilon 0.903
Apc adenomatosis polyposis coli 0.895
Vcl vinculin 0.886
Nf1 neurofibromatosis 1 0.873
Enah enabled homolog (Drosophila) 0.862
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.855
Ptrf polymerase I and transcript release factor 0.852
Ldb3 LIM domain binding 3 0.851
Arpc4 actin related protein 2/3 complex, subunit 4 0.849
Myh9 myosin, heavy polypeptide 9, non-muscle 0.842
Hif1a hypoxia inducible factor 1, alpha subunit 0.842
Lmna lamin A 0.833
Cbl Casitas B-lineage lymphoma 0.810
Pxn paxillin 0.809
Actb actin, beta 0.802
Myo7a myosin VIIA 0.799
Cdh23 cadherin 23 (otocadherin) 0.762
Itga5 integrin alpha 5 (fibronectin receptor alpha) 0.758
Was Wiskott-Aldrich syndrome homolog (human) 0.754
Cnn1 calponin 1 0.751
Wwtr1 WW domain containing transcription regulator 1 0.746
Rap1b RAS related protein 1b 0.725
Ephb2 Eph receptor B2 0.716
Cnn2 calponin 2 0.708
Wnt6 wingless-related MMTV integration site 6 0.704
Arrb2 arrestin, beta 2 0.703
Dnm1 dynamin 1 0.703
Pten phosphatase and tensin homolog 0.703
Tgfb1 transforming growth factor, beta 1 0.701
Cltc clathrin, heavy polypeptide (Hc) 0.688
Ptk2 PTK2 protein tyrosine kinase 2 0.683
Rhog ras homolog gene family, member G 0.661
Tgfb1i1 transforming growth factor beta 1 induced transcript 1 0.660
Iqgap1 IQ motif containing GTPase activating protein 1 0.639
Bcl2 B-cell leukemia/lymphoma 2 0.636
Ret ret proto-oncogene 0.636
Notch2 Notch gene homolog 2 (Drosophila) 0.629
Acta2 actin, alpha 2, smooth muscle, aorta 0.621
Bcar1 breast cancer anti-estrogen resistance 1 0.619
Cfl1 cofilin 1, non-muscle 0.619
Csrp1 cysteine and glycine-rich protein 1 0.619
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.617
Pfn1 profilin 1 0.614
Fgfr1 fibroblast growth factor receptor 1 0.605
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.601
Lama5 laminin, alpha 5 0.592
Rhoa ras homolog gene family, member A 0.582
Cryab crystallin, alpha B 0.582
Cotl1 coactosin-like 1 (Dictyostelium) 0.574
Actn2 actinin alpha 2 0.571
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.565
Myl9 myosin, light polypeptide 9, regulatory 0.561
Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha 0.560
Cd44 CD44 antigen 0.555
Vangl2 vang-like 2 (van gogh, Drosophila) 0.550
Ptk7 PTK7 protein tyrosine kinase 7 0.548
Arhgap1 Rho GTPase activating protein 1 0.548
Blnk B-cell linker 0.540
Zyx zyxin 0.532
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.531
Kit kit oncogene 0.529
Ptprq protein tyrosine phosphatase, receptor type, Q 0.525
Actc1 actin, alpha, cardiac muscle 1 0.522
Laptm5 lysosomal-associated protein transmembrane 5 0.520
Myadm myeloid-associated differentiation marker 0.517
Myo6 myosin VI 0.515
Mark4 MAP/microtubule affinity-regulating kinase 4 0.515
Efnb1 ephrin B1 0.514
Lepr leptin receptor 0.514
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.502
Vav2 vav 2 oncogene 0.500
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.498
Csf1 colony stimulating factor 1 (macrophage) 0.495
Vhl von Hippel-Lindau tumor suppressor 0.494
Flna filamin, alpha 0.491
Dlg4 discs, large homolog 4 (Drosophila) 0.491
Fyn Fyn proto-oncogene 0.487
Arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.486
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Myh9 myosin, heavy chain 9, non-muscle 0.691
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.539
Wdr1 WD repeat domain 1 0.498
Arpc2 actin related protein 2/3 complex, subunit 2 0.488
Efhd2 EF-hand domain family, member D2 0.427
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.341
Tagln transgelin 0.310
Lmna lamin A 0.280
Pfn1 profilin 1 0.183
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.171
Coro1a coronin, actin binding protein 1A 0.162
Inpp5d inositol polyphosphate-5-phosphatase D 0.160
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.113
Fam129b family with sequence similarity 129, member B 0.103
Ptbp1 polypyrimidine tract binding protein 1 0.103
Arf6 ADP-ribosylation factor 6 0.101
Csrp1 cysteine and glycine-rich protein 1 0.099
Arpc1b actin related protein 2/3 complex, subunit 1B 0.096
Col12a1 collagen, type XII, alpha 1 0.095
Cttn cortactin 0.088
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.083
Actn1 actinin, alpha 1 0.082
Tgfb1 transforming growth factor, beta 1 0.080
Timp3 TIMP metallopeptidase inhibitor 3 0.077
Hsph1 heat shock 105/110 protein 1 0.075
Cd37 CD37 molecule 0.075
Tpm3 tropomyosin 3, gamma 0.070
Tubb5 tubulin, beta 5 0.069
Map2k1 mitogen activated protein kinase kinase 1 0.069
Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.064
Lbr lamin B receptor 0.064
Laptm5 lysosomal protein transmembrane 5 0.062
Jak2 Janus kinase 2 0.061
Il1b interleukin 1 beta 0.060
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.059
Hck hemopoietic cell kinase 0.058
Mobkl2a MOB1, Mps One Binder kinase activator-like 2A (yeast) 0.058
Myl9 myosin, light chain 9, regulatory 0.058
Myo1c myosin IC 0.057
Myh7 myosin, heavy chain 7, cardiac muscle, beta 0.057
Pls3 plastin 3 (T-isoform) 0.053
Tpm1 tropomyosin 1, alpha 0.053
Hk1 hexokinase 1 0.053
Tmpo thymopoietin 0.052
Ankrd1 ankyrin repeat domain 1 (cardiac muscle) 0.052
Vav1 vav 1 guanine nucleotide exchange factor 0.051
Acta2 smooth muscle alpha-actin 0.049
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.048
Anxa2 annexin A2 0.047
RGD1306474 similar to RIKEN cDNA 9530003J23 0.047
Galnt1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) 0.047
Csnk1a1 casein kinase 1, alpha 1 0.044
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.044
Ptprc protein tyrosine phosphatase, receptor type, C 0.044
Mep1a meprin 1 alpha 0.042
Egfl7 EGF-like-domain, multiple 7 0.042
Pnoc prepronociceptin 0.041
Atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.041
Tpm4 tropomyosin 4 0.041
Exoc5 exocyst complex component 5 0.041
Gja6 gap junction protein, alpha 6 0.040
Actg2 actin, gamma 2, smooth muscle, enteric 0.040
Oprl1 opiate receptor-like 1 0.040
Flna filamin A, alpha 0.039
Cfp complement factor properdin 0.039
Chrna4 cholinergic receptor, nicotinic, alpha 4 0.039
Myo1f myosin IF 0.038
Src v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.038
Ube2d4 ubiquitin-conjugating enzyme E2D 4 0.038
Myo1g myosin IG 0.037
Akt1 v-akt murine thymoma viral oncogene homolog 1 0.037
Sf1 splicing factor 1 0.037
Plek pleckstrin 0.037
Jak1 Janus kinase 1 0.036
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.036
Cfl1 cofilin 1, non-muscle 0.036
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.036
Rac1 ras-related C3 botulinum toxin substrate 1 0.036
Arhgdib Rho, GDP dissociation inhibitor (GDI) beta 0.035
Rab2a RAB2A, member RAS oncogene family 0.035
Cd53 Cd53 molecule 0.035
Cd82 Cd82 molecule 0.035
RGD1559748 similar to Palate lung and nasal carcinoma-like protein precursor (Tongue plunc-like protein) 0.035
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.035
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.034
Mapk3 mitogen activated protein kinase 3 0.034
Lcp1 lymphocyte cytosolic protein 1 0.034
Mapk1 mitogen activated protein kinase 1 0.033
Aqp2 aquaporin 2 (collecting duct) 0.033
Cst7 cystatin F (leukocystatin) 0.033
Sirpa signal-regulatory protein alpha 0.033
Myh11 myosin, heavy chain 11, smooth muscle 0.033
Ddr1 discoidin domain receptor tyrosine kinase 1 0.032
Pak2 p21 protein (Cdc42/Rac)-activated kinase 2 0.032
Epsti1 epithelial stromal interaction 1 (breast) 0.032
Map3k3 mitogen activated protein kinase kinase kinase 3 0.032
Fgfr2 fibroblast growth factor receptor 2 0.032
Rap1b RAP1B, member of RAS oncogene family 0.031
Tcf4 transcription factor 4 0.031
Tmed2 transmembrane emp24 domain trafficking protein 2 0.031