The network for 'regulation of glucose metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of glucose metabolic process

Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
FYV10 Fyv10p 0.990
VID30 Vid30p 0.907
GID8 Gid8p 0.860
GID7 Gid7p 0.857
RMD5 Rmd5p 0.803
GSY2 Gsy2p 0.789
GSY1 Gsy1p 0.569
VID28 Vid28p 0.381
TMA10 Tma10p 0.330
PIG2 Pig2p 0.237
GLC7 Glc7p 0.196
HXK1 Hxk1p 0.161
YIL077C hypothetical protein 0.142
YAP6 Yap6p 0.114
GIP2 Gip2p 0.113
YLR345W hypothetical protein 0.110
GAC1 Gac1p 0.096
MOH1 Moh1p 0.090
GLG2 Glg2p 0.088
SAK1 Sak1p 0.074
PSK1 Psk1p 0.065
GPH1 Gph1p 0.064
BDH1 Bdh1p 0.064
PFK1 Pfk1p 0.060
CAK1 Cak1p 0.059
GBP2 Gbp2p 0.057
THI3 Thi3p 0.057
REG1 Reg1p 0.056
UGP1 Ugp1p 0.054
YNL194C hypothetical protein 0.054
PCL10 Pcl10p 0.054
OSH2 Osh2p 0.054
PHO85 Pho85p 0.053
SUR1 Sur1p 0.051
AZF1 Azf1p 0.050
SNF1 Snf1p 0.049
BCK2 Bck2p 0.049
PKH2 Pkh2p 0.046
PPE1 Ppe1p 0.046
UBP11 Ubp11p 0.045
HXK2 Hxk2p 0.045
EMI2 Emi2p 0.042
SSA4 Ssa4p 0.042
KIN1 Kin1p 0.041
VID24 Vid24p 0.039
DBF2 Dbf2p 0.037
BPH1 Bph1p 0.036
YPL229W hypothetical protein 0.035
GIS1 Gis1p 0.035
SPR6 Spr6p 0.034
MBR1 Mbr1p 0.034
GLG1 Glg1p 0.034
PHO81 Pho81p 0.034
YLR264C-A hypothetical protein 0.032
MIG1 Mig1p 0.032
RRF1 Rrf1p 0.032
ATG20 Atg20p 0.031
PET494 Pet494p 0.031
CCP1 Ccp1p 0.031
LEE1 Lee1p 0.031
MMR1 Mmr1p 0.030
NGG1 Ngg1p 0.030
MRK1 Mrk1p 0.030
SIP1 Sip1p 0.030
RIM4 Rim4p 0.030
HER1 Her1p 0.030
ACF4 Acf4p 0.029
PCL2 Pcl2p 0.029
YDR319C hypothetical protein 0.029
IRC15 Irc15p 0.029
AGP2 Agp2p 0.028
GDS1 Gds1p 0.028
NCE103 Nce103p 0.028
GLN1 Gln1p 0.028
AUS1 Aus1p 0.028
VMA3 Vma3p 0.027
YLR177W hypothetical protein 0.027
YMR210W hypothetical protein 0.027
GYL1 Gyl1p 0.026
YAP1801 hypothetical protein 0.026
YOL014W hypothetical protein 0.026
IMD2 Imd2p 0.026
PCL9 Pcl9p 0.026
LEU2 Leu2p 0.026
PAM1 Pam1p 0.026
MMF1 Mmf1p 0.026
SRD1 Srd1p 0.026
AST2 Ast2p 0.025
URN1 Urn1p 0.025
RCN2 Rcn2p 0.025
SPO12 Spo12p 0.025
CUP1-1 Cup1-1p 0.025
KIN28 Kin28p 0.024
JHD2 Jhd2p 0.024
YJR115W hypothetical protein 0.024
CKS1 Cks1p 0.023
ADR1 Adr1p 0.023
PCD1 Pcd1p 0.023
NUT2 Nut2p 0.023
GAL83 Gal83p 0.023
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
INSR insulin receptor 0.999
C1QA complement component 1, q subcomponent, A chain 0.966
NCOA1 nuclear receptor coactivator 1 0.946
AR androgen receptor 0.873
IRS2 insulin receptor substrate 2 0.859
PGK1 phosphoglycerate kinase 1 0.856
GRB10 growth factor receptor-bound protein 10 0.856
IRS1 insulin receptor substrate 1 0.819
CREBBP CREB binding protein 0.736
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 0.725
ESR1 estrogen receptor 1 0.704
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.668
IGF1R insulin-like growth factor 1 receptor 0.659
TADA3 transcriptional adaptor 3 0.633
GHR growth hormone receptor 0.589
RXRA retinoid X receptor, alpha 0.538
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.517
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.438
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.395
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.353
ZNF746 zinc finger protein 746 0.331
NOXA1 NADPH oxidase activator 1 0.329
HNF4A hepatocyte nuclear factor 4, alpha 0.276
ALDOA aldolase A, fructose-bisphosphate 0.247
TPI1 triosephosphate isomerase 1 0.243
RARA retinoic acid receptor, alpha 0.203
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.198
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.196
SQSTM1 sequestosome 1 0.190
ENO1 enolase 1, (alpha) 0.166
LDHA lactate dehydrogenase A 0.159
FHL2 four and a half LIM domains 2 0.152
EP300 E1A binding protein p300 0.146
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.137
SH2B1 SH2B adaptor protein 1 0.136
C1QC complement component 1, q subcomponent, C chain 0.132
GSK3B glycogen synthase kinase 3 beta 0.123
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.111
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.108
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.098
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 0.096
USP22 ubiquitin specific peptidase 22 0.096
ACACA acetyl-CoA carboxylase alpha 0.091
PDPK1 3-phosphoinositide dependent protein kinase-1 0.088
C1QB complement component 1, q subcomponent, B chain 0.086
KAT2B K(lysine) acetyltransferase 2B 0.085
LZTS2 leucine zipper, putative tumor suppressor 2 0.084
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.083
NCOA6 nuclear receptor coactivator 6 0.082
STAT5B signal transducer and activator of transcription 5B 0.079
RAB6A RAB6A, member RAS oncogene family 0.079
ITGB1BP3 integrin beta 1 binding protein 3 0.078
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.066
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.065
SIRT1 sirtuin 1 0.065
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.060
TADA2A transcriptional adaptor 2A 0.059
HR hairless homolog (mouse) 0.059
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.058
FOXO3 forkhead box O3 0.056
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 0.052
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.052
TRRAP transformation/transcription domain-associated protein 0.051
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 0.051
PRKCZ protein kinase C, zeta 0.050
FUNDC2 FUN14 domain containing 2 0.049
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.047
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.045
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 0.045
SORBS3 sorbin and SH3 domain containing 3 0.043
GCK glucokinase (hexokinase 4) 0.041
PRKCA protein kinase C, alpha 0.038
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 0.038
TP53 tumor protein p53 0.037
NCOA3 nuclear receptor coactivator 3 0.036
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 0.035
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.035
PKM2 pyruvate kinase, muscle 0.035
MED25 mediator complex subunit 25 0.034
PROX1 prospero homeobox 1 0.034
OSBP oxysterol binding protein 0.034
GPI glucose-6-phosphate isomerase 0.033
PARD6B par-6 partitioning defective 6 homolog beta (C. elegans) 0.033
CCDC101 coiled-coil domain containing 101 0.033
HIPK2 homeodomain interacting protein kinase 2 0.033
CREB1 cAMP responsive element binding protein 1 0.033
SMAD3 SMAD family member 3 0.031
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.030
PECAM1 platelet/endothelial cell adhesion molecule 0.030
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.030
ULK1 unc-51-like kinase 1 (C. elegans) 0.030
GABARAPL1 GABA(A) receptor-associated protein like 1 0.030
APC adenomatous polyposis coli 0.030
NCF1 neutrophil cytosolic factor 1 0.029
C5orf41 chromosome 5 open reading frame 41 0.028
PINK1 PTEN induced putative kinase 1 0.027
PRKCB protein kinase C, beta 0.027
CDCP1 CUB domain containing protein 1 0.027
ARIH1 ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) 0.026
ARF4 ADP-ribosylation factor 4 0.025
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Mus musculus
Name Description Probability Func Analog Organism
Insr insulin receptor 0.999
Lepr leptin receptor 0.995
Esr1 estrogen receptor 1 (alpha) 0.976
Lep leptin 0.961
Irs2 insulin receptor substrate 2 0.919
Prlr prolactin receptor 0.888
Nos1 nitric oxide synthase 1, neuronal 0.866
Ghr growth hormone receptor 0.832
Egfr epidermal growth factor receptor 0.759
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.746
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.722
Igf1 insulin-like growth factor 1 0.604
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.581
Thrb thyroid hormone receptor beta 0.572
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.542
Pim3 proviral integration site 3 0.524
Igf1r insulin-like growth factor I receptor 0.510
Pnpla2 patatin-like phospholipase domain containing 2 0.493
Stat5a signal transducer and activator of transcription 5A 0.491
Drd2 dopamine receptor D2 0.477
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.476
Akt1 thymoma viral proto-oncogene 1 0.474
Pparg peroxisome proliferator activated receptor gamma 0.470
Ar androgen receptor 0.443
Hnf4a hepatic nuclear factor 4, alpha 0.429
Mup19 major urinary protein 19 0.394
Thra thyroid hormone receptor alpha 0.389
Cav1 caveolin 1, caveolae protein 0.385
Ins2 insulin II 0.365
Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.360
Ctnnb1 catenin (cadherin associated protein), beta 1 0.353
Onecut1 one cut domain, family member 1 0.352
LOC100048884 novel member of the major urinary protein (Mup) gene family 0.329
Foxa2 forkhead box A2 0.327
Lmx1b LIM homeobox transcription factor 1 beta 0.326
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.310
Plin4 perilipin 4 0.310
Lipe lipase, hormone sensitive 0.301
Fgg fibrinogen gamma chain 0.295
Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C 0.293
Npy1r neuropeptide Y receptor Y1 0.272
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.269
Ren1 renin 1 structural 0.262
Ccnl2 cyclin L2 0.261
Mup4 major urinary protein 4 0.257
Ambp alpha 1 microglobulin/bikunin 0.254
Gli3 GLI-Kruppel family member GLI3 0.248
Fgfr1 fibroblast growth factor receptor 1 0.244
Pdx1 pancreatic and duodenal homeobox 1 0.240
Apoe apolipoprotein E 0.239
Mup10 major urinary protein 10 0.237
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.231
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.226
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.220
Mecom MDS1 and EVI1 complex locus 0.220
Mup1 major urinary protein 1 0.215
Clk4 CDC like kinase 4 0.214
Fga fibrinogen alpha chain 0.214
Ep300 E1A binding protein p300 0.209
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.208
Fabp1 fatty acid binding protein 1, liver 0.204
Bmp4 bone morphogenetic protein 4 0.188
Foxc1 forkhead box C1 0.182
Mup7 major urinary protein 7 0.178
Inhbc inhibin beta-C 0.177
F2 coagulation factor II 0.175
Rpgrip1l Rpgrip1-like 0.174
Kl klotho 0.174
Apof apolipoprotein F 0.170
Esr2 estrogen receptor 2 (beta) 0.170
Clk1 CDC-like kinase 1 0.168
Fgf21 fibroblast growth factor 21 0.163
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.161
Stat5b signal transducer and activator of transcription 5B 0.154
Rad21 RAD21 homolog (S. pombe) 0.153
Grb10 growth factor receptor bound protein 10 0.152
Mup12 major urinary protein 12 0.144
Mup8 major urinary protein 8 0.143
Mup13 major urinary protein 13 0.142
Foxo1 forkhead box O1 0.141
Stat3 signal transducer and activator of transcription 3 0.140
Atxn1 ataxin 1 0.140
Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 0.140
Rbl2 retinoblastoma-like 2 0.140
Mup17 major urinary protein 17 0.137
Agrp agouti related protein 0.136
Adra2a adrenergic receptor, alpha 2a 0.136
Aebp1 AE binding protein 1 0.135
Chrna6 cholinergic receptor, nicotinic, alpha polypeptide 6 0.133
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.132
Hrg histidine-rich glycoprotein 0.131
Serpina3c serine (or cysteine) peptidase inhibitor, clade A, member 3C 0.130
Wnt1 wingless-related MMTV integration site 1 0.129
Adra1b adrenergic receptor, alpha 1b 0.128
Mup11 major urinary protein 11 0.126
Otp orthopedia homolog (Drosophila) 0.123
Foxf2 forkhead box F2 0.123
Mcl1 myeloid cell leukemia sequence 1 0.123
Mup9 major urinary protein 9 0.119
Sim1 single-minded homolog 1 (Drosophila) 0.118
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Rattus norvegicus
Name Description Probability Func Analog Organism
Rab1b RAB1B, member RAS oncogene family 0.018
Dbp D site of albumin promoter (albumin D-box) binding protein 0.018
Smad3 SMAD family member 3 0.018
A1cf APOBEC1 complementation factor 0.017
Snrpb small nuclear ribonucleoprotein polypeptides B and B1 0.013
Eef2 eukaryotic translation elongation factor 2 0.013
B4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.011
Acsl1 acyl-CoA synthetase long-chain family member 1 0.011
Nacc1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 0.011
Mgat3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 0.010