The network for 'pyruvate metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

pyruvate metabolic process

The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
FBA1 Fba1p 0.996
ADH1 Adh1p 0.996
ENO2 Eno2p 0.992
PGI1 Pgi1p 0.980
PDC1 Pdc1p 0.962
PFK1 Pfk1p 0.961
ENO1 Eno1p 0.953
PGK1 Pgk1p 0.931
TDH2 Tdh2p 0.918
LAT1 Lat1p 0.917
GPM1 Gpm1p 0.911
TPI1 Tpi1p 0.837
TDH3 Tdh3p 0.792
PDB1 Pdb1p 0.740
PFK2 Pfk2p 0.595
CDC19 Cdc19p 0.581
ADH3 Adh3p 0.522
PYC1 Pyc1p 0.502
TDH1 Tdh1p 0.392
ERR2 Err2p 0.380
ERR3 Err3p 0.348
GND1 Gnd1p 0.222
PYC2 Pyc2p 0.220
PDA1 Pda1p 0.217
ADH2 Adh2p 0.200
LPD1 Lpd1p 0.186
CYM1 Cym1p 0.163
ECM4 Ecm4p 0.151
TRR1 Trr1p 0.133
BNA5 Bna5p 0.131
HXK1 Hxk1p 0.128
DCS2 Dcs2p 0.126
SBP1 Sbp1p 0.126
GLN1 Gln1p 0.126
HRK1 Hrk1p 0.117
SAM2 Sam2p 0.113
PTC6 Ptc6p 0.103
AQR1 Aqr1p 0.101
PDC5 Pdc5p 0.099
ALD2 Ald2p 0.095
FAA1 Faa1p 0.087
SSM4 Ssm4p 0.083
GSF2 Gsf2p 0.079
HXK2 Hxk2p 0.077
ALD6 Ald6p 0.072
EMI2 Emi2p 0.072
IDH2 Idh2p 0.068
SWT21 Swt21p 0.067
ABM1 Abm1p 0.065
HOR2 Hor2p 0.064
GAL83 Gal83p 0.063
YIL108W hypothetical protein 0.063
PHO11 Pho11p 0.059
TIP1 Tip1p 0.058
ERR1 Err1p 0.058
SSA4 Ssa4p 0.058
CIT2 Cit2p 0.057
SUC2 Suc2p 0.055
SSA1 Ssa1p 0.054
NPT1 Npt1p 0.054
HUG1 Hug1p 0.053
GPD2 Gpd2p 0.053
RHR2 Rhr2p 0.052
GCN4 Gcn4p 0.052
YIL077C hypothetical protein 0.050
SAK1 Sak1p 0.049
OYE2 Oye2p 0.049
YDL124W hypothetical protein 0.048
ACT1 Act1p 0.048
FMP40 Fmp40p 0.047
SCT1 Sct1p 0.047
PIG1 Pig1p 0.047
SSA2 Ssa2p 0.046
AAC1 Aac1p 0.045
COX5B Cox5bp 0.044
SPG1 Spg1p 0.044
FET4 Fet4p 0.044
FMO1 Fmo1p 0.043
LEU2 Leu2p 0.043
LAP2 Lap2p 0.042
SAM1 Sam1p 0.042
GCR1 Gcr1p 0.042
YOR390W hypothetical protein 0.040
ECM13 Ecm13p 0.040
YHR009C hypothetical protein 0.040
IDP2 Idp2p 0.040
YBR296C-A hypothetical protein 0.039
GAD1 Gad1p 0.039
YML053C hypothetical protein 0.039
DDR48 Ddr48p 0.039
APA1 Apa1p 0.039
YOL013W-A hypothetical protein 0.038
GYL1 Gyl1p 0.038
NCE103 Nce103p 0.037
YAR023C hypothetical protein 0.037
YNL115C hypothetical protein 0.036
RIF2 Rif2p 0.036
IKS1 Iks1p 0.035
PCL6 Pcl6p 0.034
APE3 Ape3p 0.034
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
aldocb aldolase C, fructose-bisphosphate, b 0.984
eno1 enolase 1, (alpha) 0.826
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.773
pkm2a pyruvate kinase, muscle, a 0.723
ldha lactate dehydrogenase A4 0.715
sucla2 succinate-CoA ligase, ADP-forming, beta subunit 0.695
got2b glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2) 0.684
gpia glucose phosphate isomerase a 0.674
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.628
sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.592
tpi1b triosephosphate isomerase 1b 0.571
dlst dihydrolipoamide S-succinyltransferase 0.466
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.442
aldoaa aldolase a, fructose-bisphosphate, a 0.436
hif1ab hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b 0.413
pdha1a pyruvate dehydrogenase (lipoamide) alpha 1a 0.387
ndufa4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 0.346
pgk1 phosphoglycerate kinase 1 0.312
mxi1 max interacting protein 0.307
slc25a4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.301
brd2a bromodomain-containing 2a 0.286
ndufv1 NADH dehydrogenase (ubiquinone) flavoprotein 1 0.277
LOC560944 6-phosphofructokinase type C-like 0.227
eef2l2 eukaryotic translation elongation factor 2, like 2 0.213
irf2bp2a interferon regulatory factor 2 binding protein 2a 0.205
mt2 metallothionein 2 0.203
sox9b SRY-box containing gene 9b 0.199
dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) 0.172
rc3 rabconnectin 3 0.171
cnp 2',3'-cyclic nucleotide 3' phosphodiesterase 0.164
trim13 tripartite motif-containing 13 0.160
hspb1 heat shock protein, alpha-crystallin-related, 1 0.152
pygmb phosphorylase, glycogen (muscle) b 0.143
c1qtnf4 C1q and tumor necrosis factor related protein 4 0.142
hsp90a.2 heat shock protein 90-alpha 2 0.137
mdh1b malate dehydrogenase 1b, NAD (soluble) 0.135
shmt2 serine hydroxymethyltransferase 2 (mitochondrial) 0.130
pafah1b1a platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a 0.130
zgc:66097 zgc:66097 0.130
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.125
aco2 aconitase 2, mitochondrial 0.124
atp1b3a ATPase, Na+/K+ transporting, beta 3a polypeptide 0.123
arl4ab ADP-ribosylation factor-like 4ab 0.122
pah phenylalanine hydroxylase 0.119
ivns1abpa influenza virus NS1A binding protein a 0.117
slc9a7 solute carrier family 9 (sodium/hydrogen exchanger), member 7 0.115
ttnb titin b 0.115
slc16a3 solute carrier family 16 (monocarboxylic acid transporters), member 3 0.109
bmp15 bone morphogenetic protein 15 0.108
ptpra protein tyrosine phosphatase, receptor type, A 0.107
furina furin (paired basic amino acid cleaving enzyme) a 0.107
socs1 suppressor of cytokine signaling 1 0.107
atp6v0d1 ATPase, H+ transporting, V0 subunit D isoform 1 0.105
zgc:171802 zgc:171802 0.102
ncoa2 nuclear receptor coactivator 2 0.101
ppdpfa pancreatic progenitor cell differentiation and proliferation factor a 0.101
cfl2l cofilin 2, like 0.099
vdra vitamin D receptor a 0.093
ldb3a LIM-domain binding factor 3a 0.093
zgc:64133 zgc:64133 0.093
mdh1a malate dehydrogenase 1a, NAD (soluble) 0.093
slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 0.091
cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) 0.090
si:dkey-24l11.7 si:dkey-24l11.7 0.088
rorb RAR-related orphan receptor B 0.087
ldb3b LIM domain binding 3b 0.084
idh3a isocitrate dehydrogenase 3 (NAD+) alpha 0.082
ache acetylcholinesterase 0.080
pccb propionyl Coenzyme A carboxylase, beta polypeptide 0.080
casq2 calsequestrin 2 0.078
zgc:77655 zgc:77655 0.072
insrb insulin receptor b 0.071
ppm1aa protein phosphatase, Mg2+/Mn2+ dependent, 1Aa 0.070
pgm1 phosphoglucomutase 1 0.068
tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.068
zgc:63663 zgc:63663 0.067
myoz1b myozenin 1b 0.067
plxnb2a plexin b2a 0.066
etfa electron-transfer-flavoprotein, alpha polypeptide 0.065
aldh2a aldehyde dehydrogenase 2 family (mitochondrial)a 0.065
por P450 (cytochrome) oxidoreductase 0.065
si:dkey-12o15.1 si:dkey-12o15.1 0.065
ptprf protein tyrosine phosphatase, receptor type, F 0.065
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.062
gnb1a guanine nucleotide binding protein (G protein), beta polypeptide 1a 0.062
psen1 presenilin 1 0.062
atp5g ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9) 0.061
pdhb pyruvate dehydrogenase (lipoamide) beta 0.061
cdc42 cell division cycle 42 0.060
hk1 hexokinase 1 0.060
sec24c SEC24 family, member C (S. cerevisiae) 0.059
furinb furin (paired basic amino acid cleaving enzyme) b 0.059
myca myelocytomatosis oncogene a 0.058
fam20b family with sequence similarity 20, member B (H. sapiens) 0.058
zgc:56376 zgc:56376 0.057
capzb capping protein (actin filament) muscle Z-line, beta 0.057
appa amyloid beta (A4) precursor protein a 0.056
rarga retinoic acid receptor gamma a 0.055
rp42-pen rp42 homolog (pending) and rp42 homolog 0.055
zgc:91930 zgc:91930 0.055
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Pgi Phosphoglucose isomerase 0.610
Eno Enolase 0.590
Pgk Phosphoglycerate kinase 0.452
GlyP Glycogen phosphorylase 0.413
Got2 Glutamate oxaloacetate transaminase 2 0.359
Tpi Triose phosphate isomerase 0.353
Men Malic enzyme 0.303
Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1 0.300
Pgm Phosphogluconate mutase 0.296
CG8036 CG8036 gene product from transcript CG8036-RB 0.239
PyK Pyruvate kinase 0.226
CG7998 CG7998 gene product from transcript CG7998-RA 0.132
Argk Arginine kinase 0.110
CG5028 CG5028 gene product from transcript CG5028-RB 0.103
Pglym78 Phosphoglyceromutase 0.101
CG5214 CG5214 gene product from transcript CG5214-RA 0.083
sea scheggia 0.075
Adh Alcohol dehydrogenase 0.069
ATPsyn-gamma ATP synthase-gamma chain 0.061
Thor CG8846 gene product from transcript CG8846-RA 0.044
CG7920 CG7920 gene product from transcript CG7920-RA 0.038
Mnt CG13316 gene product from transcript CG13316-RD 0.037
CG33138 CG33138 gene product from transcript CG33138-RA 0.030
CG11876 CG11876 gene product from transcript CG11876-RA 0.030
S6k RPS6-p70-protein kinase 0.028
CG11198 CG11198 gene product from transcript CG11198-RB 0.025
Idh Isocitrate dehydrogenase 0.025
Gpdh Glycerol 3 phosphate dehydrogenase 0.025
CG6439 CG6439 gene product from transcript CG6439-RA 0.019
scyl scylla 0.019
Zw Zwischenferment 0.017
Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2 0.016
blw bellwether 0.015
CG3731 CG3731 gene product from transcript CG3731-RA 0.014
CG5362 CG5362 gene product from transcript CG5362-RA 0.014
ND75 NADH:ubiquinone reductase 75kD subunit precursor 0.013
CG10750 CG10750 gene product from transcript CG10750-RA 0.012
l(1)G0156 lethal (1) G0156 0.012
ade5 CG3989 gene product from transcript CG3989-RA 0.012
Hex-A Hexokinase A 0.011
slmo slowmo 0.011
CG6904 CG6904 gene product from transcript CG6904-RC 0.010
Mlp84B Muscle LIM protein at 84B 0.010
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
ALDOA aldolase A, fructose-bisphosphate 0.999
LDHA lactate dehydrogenase A 0.993
TPI1 triosephosphate isomerase 1 0.975
GPI glucose-6-phosphate isomerase 0.969
ENO1 enolase 1, (alpha) 0.966
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.964
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 0.859
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.856
NCOR2 nuclear receptor corepressor 2 0.832
PKM2 pyruvate kinase, muscle 0.802
PGK1 phosphoglycerate kinase 1 0.794
HNF4A hepatocyte nuclear factor 4, alpha 0.790
PDHX pyruvate dehydrogenase complex, component X 0.749
NCOR1 nuclear receptor corepressor 1 0.714
PPARA peroxisome proliferator-activated receptor alpha 0.582
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.368
TUBGCP4 tubulin, gamma complex associated protein 4 0.340
INSR insulin receptor 0.268
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.229
IRS1 insulin receptor substrate 1 0.224
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.200
IGF1R insulin-like growth factor 1 receptor 0.180
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.179
ITGB1BP3 integrin beta 1 binding protein 3 0.157
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 0.152
PGAM1 phosphoglycerate mutase 1 (brain) 0.152
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 0.124
VDAC1 voltage-dependent anion channel 1 0.112
GRB10 growth factor receptor-bound protein 10 0.104
GYS1 glycogen synthase 1 (muscle) 0.099
BBS1 Bardet-Biedl syndrome 1 0.095
RXRA retinoid X receptor, alpha 0.086
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.086
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 0.080
PFKP phosphofructokinase, platelet 0.077
EGLN1 egl nine homolog 1 (C. elegans) 0.074
HK1 hexokinase 1 0.074
EGFR epidermal growth factor receptor 0.072
ALDOC aldolase C, fructose-bisphosphate 0.070
AGXT2 alanine--glyoxylate aminotransferase 2 0.068
GHR growth hormone receptor 0.066
BCL6 B-cell CLL/lymphoma 6 0.066
TKT transketolase 0.065
FAF1 Fas (TNFRSF6) associated factor 1 0.060
HDAC4 histone deacetylase 4 0.060
HDAC3 histone deacetylase 3 0.058
VEGFA vascular endothelial growth factor A 0.057
PDHB pyruvate dehydrogenase (lipoamide) beta 0.054
IRS2 insulin receptor substrate 2 0.053
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.052
MEF2A myocyte enhancer factor 2A 0.050
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.048
ESR1 estrogen receptor 1 0.044
PTN pleiotrophin 0.041
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 0.040
HR hairless homolog (mouse) 0.040
PGR progesterone receptor 0.037
BTRC beta-transducin repeat containing 0.037
IGF2R insulin-like growth factor 2 receptor 0.037
BCKDK branched chain ketoacid dehydrogenase kinase 0.037
SLC16A3 solute carrier family 16, member 3 (monocarboxylic acid transporter 4) 0.036
FBP2 fructose-1,6-bisphosphatase 2 0.036
TXNIP thioredoxin interacting protein 0.036
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.035
ING2 inhibitor of growth family, member 2 0.034
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.034
ESRRG estrogen-related receptor gamma 0.032
ILVBL ilvB (bacterial acetolactate synthase)-like 0.031
TUBA4A tubulin, alpha 4a 0.031
MARS methionyl-tRNA synthetase 0.031
NCOA1 nuclear receptor coactivator 1 0.029
PGM1 phosphoglucomutase 1 0.029
MAP4 microtubule-associated protein 4 0.028
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 0.028
NR2E3 nuclear receptor subfamily 2, group E, member 3 0.028
EGLN3 egl nine homolog 3 (C. elegans) 0.028
SGK3 serum/glucocorticoid regulated kinase family, member 3 0.028
PFDN1 prefoldin subunit 1 0.027
MEF2C myocyte enhancer factor 2C 0.027
PDK1 pyruvate dehydrogenase kinase, isozyme 1 0.027
ENO2 enolase 2 (gamma, neuronal) 0.027
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.027
GOT1 glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) 0.026
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.026
STAT5A signal transducer and activator of transcription 5A 0.026
GCKR glucokinase (hexokinase 4) regulator 0.024
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.024
CARS cysteinyl-tRNA synthetase 0.023
STAT5B signal transducer and activator of transcription 5B 0.023
ALDOB aldolase B, fructose-bisphosphate 0.022
JAK2 Janus kinase 2 0.022
MLX MAX-like protein X 0.022
EPAS1 endothelial PAS domain protein 1 0.022
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.020
DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.020
PGAM2 phosphoglycerate mutase 2 (muscle) 0.020
PFKL phosphofructokinase, liver 0.019
SRSF5 serine/arginine-rich splicing factor 5 0.019
HDAC5 histone deacetylase 5 0.018
EPOR erythropoietin receptor 0.018
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Aldoa aldolase A, fructose-bisphosphate 1.000
Tpi1 triosephosphate isomerase 1 0.999
Pkm2 pyruvate kinase, muscle 0.999
Ldha lactate dehydrogenase A 0.997
Gpi1 glucose phosphate isomerase 1 0.995
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.995
Gm5506 predicted gene 5506 0.982
Pparg peroxisome proliferator activated receptor gamma 0.968
Pgk1 phosphoglycerate kinase 1 0.936
Pnpla2 patatin-like phospholipase domain containing 2 0.895
Mef2d myocyte enhancer factor 2D 0.895
Lepr leptin receptor 0.833
Pfkl phosphofructokinase, liver, B-type 0.785
Stat5b signal transducer and activator of transcription 5B 0.766
Irf9 interferon regulatory factor 9 0.729
Pgam1 phosphoglycerate mutase 1 0.701
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.555
Ghr growth hormone receptor 0.550
Stat5a signal transducer and activator of transcription 5A 0.520
Drd2 dopamine receptor D2 0.472
Hnf4a hepatic nuclear factor 4, alpha 0.455
Cav1 caveolin 1, caveolae protein 0.415
Hbb-b1 hemoglobin, beta adult major chain 0.323
Mef2c myocyte enhancer factor 2C 0.304
Prlr prolactin receptor 0.274
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.265
Cyp2d26 cytochrome P450, family 2, subfamily d, polypeptide 26 0.257
Egln1 EGL nine homolog 1 (C. elegans) 0.229
Npy1r neuropeptide Y receptor Y1 0.205
Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 0.203
Kl klotho 0.200
Adrb1 adrenergic receptor, beta 1 0.199
Insr insulin receptor 0.183
Lep leptin 0.181
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.175
Ndufs1 NADH dehydrogenase (ubiquinone) Fe-S protein 1 0.148
Ncoa3 nuclear receptor coactivator 3 0.138
Thrsp thyroid hormone responsive SPOT14 homolog (Rattus) 0.119
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.103
Gck glucokinase 0.100
Il4ra interleukin 4 receptor, alpha 0.100
Adrb2 adrenergic receptor, beta 2 0.096
Clcnka chloride channel Ka 0.095
Pgm2 phosphoglucomutase 2 0.083
Adrb3 adrenergic receptor, beta 3 0.082
Thra thyroid hormone receptor alpha 0.080
Ppara peroxisome proliferator activated receptor alpha 0.076
Hsd3b4 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 0.075
Bsg basigin 0.072
Gys1 glycogen synthase 1, muscle 0.071
Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.068
Max Max protein 0.068
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.068
Plin4 perilipin 4 0.067
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.063
Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) 0.062
Vegfb vascular endothelial growth factor B 0.062
Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 0.061
Pfkm phosphofructokinase, muscle 0.059
Csf1 colony stimulating factor 1 (macrophage) 0.058
Bhlhe40 basic helix-loop-helix family, member e40 0.058
Nos1 nitric oxide synthase 1, neuronal 0.057
Otp orthopedia homolog (Drosophila) 0.057
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.056
Pcx pyruvate carboxylase 0.056
Npy2r neuropeptide Y receptor Y2 0.056
Sstr3 somatostatin receptor 3 0.055
Ckmt2 creatine kinase, mitochondrial 2 0.055
Kcnab3 potassium voltage-gated channel, shaker-related subfamily, beta member 3 0.055
Isca1 iron-sulfur cluster assembly 1 homolog (S. cerevisiae) 0.054
Foxo1 forkhead box O1 0.051
Ndrg2 N-myc downstream regulated gene 2 0.051
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 0.050
Gpr27 G protein-coupled receptor 27 0.050
Il1r1 interleukin 1 receptor, type I 0.050
Gcgr glucagon receptor 0.050
Zfr2 zinc finger RNA binding protein 2 0.049
Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 0.049
Grm2 glutamate receptor, metabotropic 2 0.049
Chpt1 choline phosphotransferase 1 0.048
Thrb thyroid hormone receptor beta 0.048
Lhx6 LIM homeobox protein 6 0.046
Atp4a ATPase, H+/K+ exchanging, gastric, alpha polypeptide 0.046
G6pc glucose-6-phosphatase, catalytic 0.046
Mas1 MAS1 oncogene 0.045
Cltc clathrin, heavy polypeptide (Hc) 0.045
Grid1 glutamate receptor, ionotropic, delta 1 0.044
Sim1 single-minded homolog 1 (Drosophila) 0.044
Sstr4 somatostatin receptor 4 0.044
Esr1 estrogen receptor 1 (alpha) 0.044
Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 0.043
Tat tyrosine aminotransferase 0.043
Pygm muscle glycogen phosphorylase 0.042
Bnip3 BCL2/adenovirus E1B interacting protein 3 0.042
Hdac5 histone deacetylase 5 0.042
Esr2 estrogen receptor 2 (beta) 0.042
Egln3 EGL nine homolog 3 (C. elegans) 0.041
Idh3a isocitrate dehydrogenase 3 (NAD+) alpha 0.041
Clk4 CDC like kinase 4 0.040
Arid1b AT rich interactive domain 1B (SWI-like) 0.039
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Gpi glucose phosphate isomerase 0.998
Aldoa aldolase A, fructose-bisphosphate 0.972
Eno1 enolase 1, (alpha) 0.972
Mif macrophage migration inhibitory factor 0.957
Pkm2 pyruvate kinase, muscle 0.931
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.928
Pgam1 phosphoglycerate mutase 1 (brain) 0.865
Ldha lactate dehydrogenase A 0.840
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.739
Rabac1 Rab acceptor 1 (prenylated) 0.484
Tecr trans-2,3-enoyl-CoA reductase 0.447
Tpi1 triosephosphate isomerase 1 0.390
Pgk1 phosphoglycerate kinase 1 0.313
Dld dihydrolipoamide dehydrogenase 0.305
Dlat dihydrolipoamide S-acetyltransferase 0.287
Pebp1 phosphatidylethanolamine binding protein 1 0.276
Capns1 calpain, small subunit 1 0.249
Pdk2 pyruvate dehydrogenase kinase, isozyme 2 0.241
Ndufs1 NADH dehydrogenase (ubiquinone) Fe-S protein 1 0.237
Vdac1 voltage-dependent anion channel 1 0.233
Pdhb pyruvate dehydrogenase (lipoamide) beta 0.189
Pfkm phosphofructokinase, muscle 0.159
Tst thiosulfate sulfurtransferase 0.149
Stxbp1 syntaxin binding protein 1 0.146
G6pc glucose-6-phosphatase, catalytic subunit 0.141
Phkg1 phosphorylase kinase, gamma 1 0.133
Pygm phosphorylase, glycogen, muscle 0.127
Gcgr glucagon receptor 0.118
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.114
Me1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.109
Bsg basigin 0.106
Bckdha branched chain ketoacid dehydrogenase E1, alpha polypeptide 0.104
Rxrg retinoid X receptor gamma 0.097
Lepr leptin receptor 0.090
Fgf1 fibroblast growth factor 1 0.087
Bcat1 branched chain aminotransferase 1, cytosolic 0.079
Sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.079
RGD1564560 similar to RCK 0.071
Rtn2 reticulon 2 0.065
Dnase1 deoxyribonuclease I 0.053
Uqcrc2 ubiquinol cytochrome c reductase core protein 2 0.053
Acox3 acyl-Coenzyme A oxidase 3, pristanoyl 0.051
Pgm1 phosphoglucomutase 1 0.051
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.050
Pdhx pyruvate dehydrogenase complex, component X 0.050
Sgk2 serum/glucocorticoid regulated kinase 2 0.050
Gstm2 glutathione S-transferase mu 2 0.049
Rpl3l ribosomal protein L3-like 0.048
Pdha1 pyruvate dehydrogenase (lipoamide) alpha 1 0.047
Ak1 adenylate kinase 1 0.046
Tkt transketolase 0.045
Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 0.043
Ap2b1 adaptor-related protein complex 2, beta 1 subunit 0.042
Mpst mercaptopyruvate sulfurtransferase 0.042
Nfib nuclear factor I/B 0.042
Cuzd1 CUB and zona pellucida-like domains 1 0.041
Pfkl phosphofructokinase, liver 0.041
Gip gastric inhibitory polypeptide 0.040
Mapk3 mitogen activated protein kinase 3 0.039
Mtx2 metaxin 2 0.037
Igfals insulin-like growth factor binding protein, acid labile subunit 0.037
Rab3a RAB3A, member RAS oncogene family 0.036
Fitm1 fat storage-inducing transmembrane protein 1 0.035
Tmem38a transmembrane protein 38a 0.034
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.034
Ptgs2 prostaglandin-endoperoxide synthase 2 0.033
Vegfa vascular endothelial growth factor A 0.033
Clip2 CAP-GLY domain containing linker protein 2 0.033
Aes amino-terminal enhancer of split 0.032
Ola1 Obg-like ATPase 1 0.031
Fxyd1 FXYD domain-containing ion transport regulator 1 0.031
Gpx4 glutathione peroxidase 4 0.030
Slc2a5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.030
Atp6v0a1 ATPase, H+ transporting, lysosomal V0 subunit A1 0.029
Gstm1 glutathione S-transferase mu 1 0.029
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.029
Ppard peroxisome proliferator-activated receptor delta 0.029
Slc16a1 solute carrier family 16, member 1 (monocarboxylic acid transporter 1) 0.029
Atp6v0c ATPase, H+ transporting, lysosomal V0 subunit C 0.029
Stard10 StAR-related lipid transfer (START) domain containing 10 0.028
Hibadh 3-hydroxyisobutyrate dehydrogenase 0.028
Cox8b cytochrome c oxidase, subunit VIIIb 0.028
Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 0.027
Tfrc transferrin receptor 0.027
Myh6 myosin, heavy chain 6, cardiac muscle, alpha 0.026
Il1r2 interleukin 1 receptor, type II 0.026
Akt1 v-akt murine thymoma viral oncogene homolog 1 0.026
Bpnt1 3'(2'), 5'-bisphosphate nucleotidase 1 0.025
Abp1 amiloride binding protein 1 (amine oxidase, copper-containing) 0.025
Ccng1 cyclin G1 0.025
Zfc3h1 zinc finger, C3H1-type containing 0.025
Aldob aldolase B, fructose-bisphosphate 0.024
Mosc2 MOCO sulphurase C-terminal domain containing 2 0.024
Pygb phosphorylase, glycogen; brain 0.024
Stk39 serine/threonine kinase 39, STE20/SPS1 homolog (yeast) 0.024
Actg1 actin, gamma 1 0.023
Akap1 A kinase (PRKA) anchor protein 1 0.023
Pde4d phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) 0.023
Rab11b RAB11B, member RAS oncogene family 0.023
Idh3a isocitrate dehydrogenase 3 (NAD+) alpha 0.022