The network for 'regulation of response to drug' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of response to drug

Any process that modulates the frequency, rate or extent of response to drug.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
SWI1 Swi1p 0.099
VID24 Vid24p 0.097
TRA1 Tra1p 0.087
GLN3 Gln3p 0.083
HXT3 Hxt3p 0.082
VAC7 Vac7p 0.061
NRG1 Nrg1p 0.056
TPO2 Tpo2p 0.056
MDH2 Mdh2p 0.054
KOG1 Kog1p 0.053
CSR2 Csr2p 0.051
STE5 Ste5p 0.050
MIG1 Mig1p 0.048
GAL11 Gal11p 0.048
BSD2 Bsd2p 0.047
MBR1 Mbr1p 0.046
YPL014W hypothetical protein 0.043
GND2 Gnd2p 0.042
YPR157W hypothetical protein 0.042
RGS2 Rgs2p 0.042
HOR2 Hor2p 0.041
LYS5 Lys5p 0.041
GAL4 Gal4p 0.040
YOR385W hypothetical protein 0.039
PSK2 Psk2p 0.038
ADR1 Adr1p 0.037
MOT3 Mot3p 0.036
TOF2 Tof2p 0.035
ATG29 Atg29p 0.035
HAL5 Hal5p 0.035
PHO80 Pho80p 0.034
PNS1 Pns1p 0.034
SSK2 Ssk2p 0.034
MTC4 Mtc4p 0.034
RPI1 Rpi1p 0.034
SMP1 Smp1p 0.034
RTG3 Rtg3p 0.033
ZAP1 Zap1p 0.033
SFL1 Sfl1p 0.033
YNL234W hypothetical protein 0.032
DCS2 Dcs2p 0.032
PDR5 Pdr5p 0.032
YPL150W hypothetical protein 0.031
AGC1 Agc1p 0.031
GAT2 Gat2p 0.031
SIP2 Sip2p 0.030
YNR014W hypothetical protein 0.030
GPD1 Gpd1p 0.030
YKR075C hypothetical protein 0.030
SRD1 Srd1p 0.029
PHO12 Pho12p 0.029
DAL81 Dal81p 0.029
HAL1 Hal1p 0.029
MNN4 Mnn4p 0.029
POG1 Pog1p 0.029
GUT2 Gut2p 0.029
ZWF1 Zwf1p 0.028
DBF2 Dbf2p 0.028
YAP5 Yap5p 0.028
MIG2 Mig2p 0.028
ECM30 Ecm30p 0.028
AFT1 Aft1p 0.028
LEU2 Leu2p 0.028
DIA1 Dia1p 0.027
YIR035C hypothetical protein 0.027
PUT4 Put4p 0.027
KDX1 Kdx1p 0.027
TYE7 Tye7p 0.027
YOL038C-A hypothetical protein 0.027
WAR1 War1p 0.027
FPK1 Fpk1p 0.027
AVO1 Avo1p 0.027
SBE22 Sbe22p 0.027
CHS2 Chs2p 0.026
ACS1 Acs1p 0.026
GAD1 Gad1p 0.026
TSC11 Tsc11p 0.026
BSC1 Bsc1p 0.026
YER130C hypothetical protein 0.026
YLR162W hypothetical protein 0.026
FMP48 Fmp48p 0.026
KIC1 Kic1p 0.026
HXT7 Hxt7p 0.026
YLR264C-A hypothetical protein 0.026
SAK1 Sak1p 0.026
RTG1 Rtg1p 0.026
GPH1 Gph1p 0.026
STL1 Stl1p 0.025
YIR042C hypothetical protein 0.025
CHA1 Cha1p 0.025
RIM13 Rim13p 0.025
ICY1 Icy1p 0.025
YPL066W hypothetical protein 0.025
YAR068W hypothetical protein 0.025
TIP1 Tip1p 0.025
YKL187C hypothetical protein 0.025
ACH1 Ach1p 0.025
WSC4 Wsc4p 0.025
FAA2 Faa2p 0.025
HOR7 Hor7p 0.025
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
msxe muscle segment homeobox E 0.037
LOC565632 BTB/POZ domain-containing protein 16-like 0.033
si:ch1073-268b21.1 si:ch1073-268b21.1 0.031
nkx2.1a NK2 homeobox 1a 0.021
ephb4a eph receptor B4a 0.021
dyx1c1 dyslexia susceptibility 1 candidate 1 0.018
LOC793222 cAMP-dependent protein kinase inhibitor alpha-like 0.013
ccdc73 coiled-coil domain containing 73 0.013
si:dkey-183g16.1 si:dkey-183g16.1 0.013
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.011
LOC558198 probable endonuclease 4-like 0.011
wu:fi34b01 wu:fi34b01 0.010
wu:fk73b01 wu:fk73b01 0.010
zgc:171747 zgc:171747 0.010
si:ch211-198o12.4 si:ch211-198o12.4 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
MED25 mediator complex subunit 25 0.279
MAPK1 mitogen-activated protein kinase 1 0.279
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.187
RPTOR regulatory associated protein of MTOR, complex 1 0.128
MAPK3 mitogen-activated protein kinase 3 0.125
KANK2 KN motif and ankyrin repeat domains 2 0.074
DUSP1 dual specificity phosphatase 1 0.069
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 0.063
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.056
RICTOR RPTOR independent companion of MTOR, complex 2 0.056
RXRA retinoid X receptor, alpha 0.056
AFF1 AF4/FMR2 family, member 1 0.044
MYST3 MYST histone acetyltransferase (monocytic leukemia) 3 0.042
COASY CoA synthase 0.041
RARA retinoic acid receptor, alpha 0.040
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.038
DUSP3 dual specificity phosphatase 3 0.037
PRKCA protein kinase C, alpha 0.036
AFF4 AF4/FMR2 family, member 4 0.034
DEPTOR DEP domain containing MTOR-interacting protein 0.033
NCOA3 nuclear receptor coactivator 3 0.033
C16orf53 chromosome 16 open reading frame 53 0.029
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.028
EP300 E1A binding protein p300 0.027
MAP2K1 mitogen-activated protein kinase kinase 1 0.023
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.022
MAPK14 mitogen-activated protein kinase 14 0.021
AKT1S1 AKT1 substrate 1 (proline-rich) 0.021
CCNT1 cyclin T1 0.021
NCOA6 nuclear receptor coactivator 6 0.019
HTT huntingtin 0.018
PTPRJ protein tyrosine phosphatase, receptor type, J 0.018
PTPRR protein tyrosine phosphatase, receptor type, R 0.017
NCOA2 nuclear receptor coactivator 2 0.017
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 0.016
PDK1 pyruvate dehydrogenase kinase, isozyme 1 0.016
MAPT microtubule-associated protein tau 0.016
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.016
DUSP7 dual specificity phosphatase 7 0.014
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.012
PEA15 phosphoprotein enriched in astrocytes 15 0.012
PDPK1 3-phosphoinositide dependent protein kinase-1 0.012
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.011
BRAF v-raf murine sarcoma viral oncogene homolog B1 0.011
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.010
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Gabrb2 gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 1.000
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.986
Grid1 glutamate receptor, ionotropic, delta 1 0.934
Gabra1 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 0.918
Gabra5 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5 0.916
Gabrg2 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 0.884
Rictor RPTOR independent companion of MTOR, complex 2 0.724
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.716
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1 0.658
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.613
Braf Braf transforming gene 0.577
Ep300 E1A binding protein p300 0.536
Gad2 glutamic acid decarboxylase 2 0.498
Mapkap1 mitogen-activated protein kinase associated protein 1 0.400
Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) 0.393
B3galt1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 0.379
Nxph1 neurexophilin 1 0.370
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.341
Ncoa1 nuclear receptor coactivator 1 0.324
Thrb thyroid hormone receptor beta 0.322
Rptor regulatory associated protein of MTOR, complex 1 0.308
Rit2 Ras-like without CAAX 2 0.290
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.268
Cnr1 cannabinoid receptor 1 (brain) 0.262
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.255
Scn1a sodium channel, voltage-gated, type I, alpha 0.251
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.230
Cdh9 cadherin 9 0.227
Setdb1 SET domain, bifurcated 1 0.224
Ptprr protein tyrosine phosphatase, receptor type, R 0.222
Bcl2 B-cell leukemia/lymphoma 2 0.204
Dlg4 discs, large homolog 4 (Drosophila) 0.199
Hcn1 hyperpolarization-activated, cyclic nucleotide-gated K+ 1 0.194
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.184
Nrsn1 neurensin 1 0.182
Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) 0.179
Cdh10 cadherin 10 0.174
Kif5c kinesin family member 5C 0.172
Tnrc6c trinucleotide repeat containing 6C 0.171
Pias1 protein inhibitor of activated STAT 1 0.171
Cntn4 contactin 4 0.168
Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) 0.165
Mlst8 MTOR associated protein, LST8 homolog (S. cerevisiae) 0.150
Syt1 synaptotagmin I 0.148
Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.145
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.139
Src Rous sarcoma oncogene 0.127
Gabrg3 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3 0.125
Gabrb1 gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 0.123
Mdm2 transformed mouse 3T3 cell double minute 2 0.118
Cntn3 contactin 3 0.117
Rasgrp1 RAS guanyl releasing protein 1 0.116
Gabra2 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 0.114
Trhr thyrotropin releasing hormone receptor 0.114
Mapk14 mitogen-activated protein kinase 14 0.112
Cbl Casitas B-lineage lymphoma 0.112
Crebbp CREB binding protein 0.109
Cdh8 cadherin 8 0.109
Mid1 midline 1 0.109
Rere arginine glutamic acid dipeptide (RE) repeats 0.109
Adcyap1 adenylate cyclase activating polypeptide 1 0.106
Nap1l2 nucleosome assembly protein 1-like 2 0.104
En2 engrailed 2 0.102
Ncor1 nuclear receptor co-repressor 1 0.100
Grm8 glutamate receptor, metabotropic 8 0.100
Mapk3 mitogen-activated protein kinase 3 0.097
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 0.097
Camk4 calcium/calmodulin-dependent protein kinase IV 0.092
Nf1 neurofibromatosis 1 0.091
Neurod1 neurogenic differentiation 1 0.089
Resp18 regulated endocrine-specific protein 18 0.088
Syn2 synapsin II 0.087
Mapk8 mitogen-activated protein kinase 8 0.087
Pikfyve phosphoinositide kinase, FYVE finger containing 0.086
Macf1 microtubule-actin crosslinking factor 1 0.086
Gjd2 gap junction protein, delta 2 0.085
Mll3 myeloid/lymphoid or mixed-lineage leukemia 3 0.083
Napb N-ethylmaleimide sensitive fusion protein attachment protein beta 0.081
Dync1i1 dynein cytoplasmic 1 intermediate chain 1 0.080
En1 engrailed 1 0.080
Pea15a phosphoprotein enriched in astrocytes 15A 0.079
Slc12a5 solute carrier family 12, member 5 0.077
Mgat4c mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative) 0.076
Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit 0.076
Glg1 golgi apparatus protein 1 0.076
Prkcc protein kinase C, gamma 0.074
Plcb1 phospholipase C, beta 1 0.074
Oprk1 opioid receptor, kappa 1 0.067
Npy1r neuropeptide Y receptor Y1 0.067
Cadps Ca2+-dependent secretion activator 0.067
Fbxw7 F-box and WD-40 domain protein 7 0.065
Dlg2 discs, large homolog 2 (Drosophila) 0.064
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.064
Ash1l ash1 (absent, small, or homeotic)-like (Drosophila) 0.063
Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) 0.061
Map3k5 mitogen-activated protein kinase kinase kinase 5 0.061
Gpatch2 G patch domain containing 2 0.061
Tsc1 tuberous sclerosis 1 0.060
Mapk1 mitogen-activated protein kinase 1 0.059
Bsn bassoon 0.058
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Rattus norvegicus
Name Description Probability Func Analog Organism
Dnm1l dynamin 1-like 0.013