The network for 'phosphatidylcholine biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

phosphatidylcholine biosynthetic process

The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
CDS1 Cds1p 0.122
MDM35 Mdm35p 0.114
EHT1 Eht1p 0.099
CPT1 Cpt1p 0.081
KES1 Kes1p 0.073
EPT1 Ept1p 0.057
SAM2 Sam2p 0.047
TGL1 Tgl1p 0.037
FAA1 Faa1p 0.037
PSD1 Psd1p 0.034
UPS3 Ups3p 0.030
IMD2 Imd2p 0.028
OPI3 Opi3p 0.027
INO1 Ino1p 0.026
SDS3 Sds3p 0.025
IZH4 Izh4p 0.025
OLE1 Ole1p 0.024
PLB2 Plb2p 0.024
CHO1 Cho1p 0.024
YGR205W hypothetical protein 0.023
CTI6 Cti6p 0.023
CSF1 Csf1p 0.023
YLR132C hypothetical protein 0.023
CHO2 Cho2p 0.022
OPI1 Opi1p 0.022
URA8 Ura8p 0.021
CKI1 Cki1p 0.020
SLC1 Slc1p 0.020
YOL107W hypothetical protein 0.019
NUP49 Nup49p 0.018
AYR1 Ayr1p 0.017
YHB1 Yhb1p 0.017
YLR264C-A hypothetical protein 0.017
PBP4 Pbp4p 0.016
ARE2 Are2p 0.016
UPS1 Ups1p 0.016
HLR1 Hlr1p 0.016
YJU3 Yju3p 0.016
IME1 Ime1p 0.016
CRN1 Crn1p 0.016
MOG1 Mog1p 0.016
SRD1 Srd1p 0.015
YIP3 Yip3p 0.015
YJL107C hypothetical protein 0.015
VPS75 Vps75p 0.015
DNM1 Dnm1p 0.015
SPE3 Spe3p 0.015
YPC1 Ypc1p 0.015
HTD2 Htd2p 0.015
ARP10 Arp10p 0.015
FRK1 Frk1p 0.015
GDS1 Gds1p 0.014
LAT1 Lat1p 0.014
CAR1 Car1p 0.014
LEU2 Leu2p 0.014
YIR035C hypothetical protein 0.014
SPT16 Spt16p 0.014
YOL038C-A hypothetical protein 0.014
FAA2 Faa2p 0.014
GLN1 Gln1p 0.014
CRP1 Crp1p 0.014
YAR068W hypothetical protein 0.013
YPR157W hypothetical protein 0.013
URA3 Ura3p 0.013
TPS3 Tps3p 0.013
YJL218W hypothetical protein 0.013
MDM34 Mdm34p 0.013
FMT1 Fmt1p 0.013
MER1 Mer1p 0.013
YJR116W hypothetical protein 0.013
YLR162W hypothetical protein 0.013
CHA1 Cha1p 0.013
SCM4 Scm4p 0.013
OYE2 Oye2p 0.013
YTA12 Yta12p 0.013
SPL2 Spl2p 0.013
YKR011C hypothetical protein 0.013
PBP2 Pbp2p 0.013
HO Hop 0.012
FCY21 Fcy21p 0.012
SAM3 Sam3p 0.012
HDA2 Hda2p 0.012
TRR1 Trr1p 0.012
LCB1 Lcb1p 0.012
LSB6 Lsb6p 0.012
YEL073C hypothetical protein 0.012
CUP1-1 Cup1-1p 0.012
ITR1 Itr1p 0.012
MDH2 Mdh2p 0.012
HXT3 Hxt3p 0.012
ZPS1 Zps1p 0.012
LAP4 Lap4p 0.012
LRO1 Lro1p 0.012
CPD1 Cpd1p 0.012
YAR066W hypothetical protein 0.012
OPT2 Opt2p 0.012
REE1 Ree1p 0.012
SCT1 Sct1p 0.012
RGT1 Rgt1p 0.012
DIF1 Dif1p 0.012
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
APOA1 apolipoprotein A-I 0.998
ALB albumin 0.914
HP haptoglobin 0.783
APOC1 apolipoprotein C-I 0.507
APOC3 apolipoprotein C-III 0.246
LCAT lecithin-cholesterol acyltransferase 0.246
FGFR2 fibroblast growth factor receptor 2 0.234
APOA2 apolipoprotein A-II 0.107
IPO7 importin 7 0.045
APOC2 apolipoprotein C-II 0.045
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.044
FGA fibrinogen alpha chain 0.042
MESDC2 mesoderm development candidate 2 0.041
XPOT exportin, tRNA (nuclear export receptor for tRNAs) 0.036
NUP153 nucleoporin 153kDa 0.022
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 0.022
TTR transthyretin 0.018
EIF1AX eukaryotic translation initiation factor 1A, X-linked 0.017
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.017
TNPO1 transportin 1 0.016
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) 0.014
AHSG alpha-2-HS-glycoprotein 0.013
PLTP phospholipid transfer protein 0.010
HN1 hematological and neurological expressed 1 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Tmem38b transmembrane protein 38B 0.018
Fgb fibrinogen beta chain 0.018
Apob apolipoprotein B 0.017
Ttr transthyretin 0.016
Aldob aldolase B, fructose-bisphosphate 0.016
Dram2 VDNA-damage regulated autophagy modulator 2 0.012
Mdk midkine 0.011
Stra6 stimulated by retinoic acid gene 6 0.011
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Rattus norvegicus
Name Description Probability Func Analog Organism
Lmbrd1 LMBR1 domain containing 1 0.097
Prap1 proline-rich acidic protein 1 0.054
Engase endo-beta-N-acetylglucosaminidase 0.047
Pgrmc1 progesterone receptor membrane component 1 0.045
Kcnh5 potassium voltage-gated channel, subfamily H (eag-related), member 5 0.039
Gtf2a1 general transcription factor IIA, 1 0.038
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.030
Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.029
Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 0.028
Cltc clathrin, heavy chain (Hc) 0.027
RGD1309821 similar to KIAA1161 protein 0.026
Pnpla2 patatin-like phospholipase domain containing 2 0.026
Fam108b1 family with sequence similarity 108, member B1 0.025
Cacng4 calcium channel, voltage-dependent, gamma subunit 4 0.023
Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase 0.023
Slurp1 secreted Ly6/Plaur domain containing 1 0.023
Esr2 estrogen receptor 2 (ER beta) 0.021
Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 0.020
Rabep1 rabaptin, RAB GTPase binding effector protein 1 0.019
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.019
Slc20a1 solute carrier family 20 (phosphate transporter), member 1 0.018
Acsl4 acyl-CoA synthetase long-chain family member 4 0.018
Synpo synaptopodin 0.017
Tbce tubulin folding cofactor E 0.017
RGD1309102 similar to TRS85 homolog 0.017
Fgf10 fibroblast growth factor 10 0.016
Il11 interleukin 11 0.016
Ica1l islet cell autoantigen 1-like 0.016
Tbr1 T-box, brain, 1 0.016
Pga5 pepsinogen 5, group I 0.015
Gja3 gap junction protein, alpha 3 0.015
Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 0.015
Ddx17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 0.015
Pde7b phosphodiesterase 7B 0.015
Impa1 Inositol (myo)-1(or 4)-monophosphatase 1 0.015
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.013
Adam23 ADAM metallopeptidase domain 23 0.013
St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 0.013
Dmd dystrophin 0.012
RGD1306809 similar to hypothetical protein FLJ30596 0.012
Aqp7 aquaporin 7 0.012
Slc22a7 solute carrier family 22 (organic anion transporter), member 7 0.011
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.011
LOC100362727 ubiquitin carboxyl-terminal hydrolase CYLD 0.011
Neurl3 neuralized homolog 3 (Drosophila) 0.011
Gdf9 growth differentiation factor 9 0.011
Mapk15 mitogen-activated protein kinase 15 0.011
Kcnn1 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 0.011
Nxf1 nuclear RNA export factor 1 0.011
LOC100361389 hypothetical protein LOC100361389 0.010
Itga7 integrin, alpha 7 0.010
Il17d interleukin 17D 0.010
Tex101 testis expressed 101 0.010
Fcer2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.010
Ctrc chymotrypsin C (caldecrin) 0.010
Cd36 CD36 molecule (thrombospondin receptor) 0.010
Tollip toll interacting protein 0.010